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Original Research

Drug-resistant colon cancer cells produce high carcinoembryonic antigen and might not be cancer-initiating cells

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Pages 491-502 | Published online: 17 Jun 2013

References

  • Trumpp A Wiestler OD Mechanisms of disease: cancer stem cells – targeting the evil twin Nat Clin Pract Oncol 2008 5 6 337 347 18431377
  • Bonnet D Dick JE Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell Nat Med 1997 3 7 730 737 9212098
  • Ferlay J Autier P Boniol M Heanue M Colombet M Boyle P Estimates of the cancer incidence and mortality in Europe in 2006 Ann Oncol 2007 18 3 581 592 17287242
  • Ricci-Vitiani L Fabrizi E Palio E De Maria R Colon cancer stem cells J Mol Med (Berl) 2009 87 11 1097 1104 19727638
  • Todaro M Francipane MG Medema JP Stassi G Colon cancer stem cells: promise of targeted therapy Gastroenterology 2010 138 6 2151 2162 20420952
  • Papailiou J Bramis KJ Gazouli M Theodoropoulos G Stem cells in colon cancer. A new era in cancer theory begins Int J Colorectal Dis 2011 26 1 1 11 20680304
  • Klonisch T Wiechec E Hombach-Klonisch S Cancer stem cell markers in common cancers – therapeutic implications Trends Mol Med 2008 14 10 450 460 18775674
  • Ricci-Vitiani L Lombardi DG Pilozzi E Identification and expansion of human colon-cancer-initiating cells Nature 2007 445 7123 111 115 17122771
  • Vermeulen L Todaro M de Sousa Mello F Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity Proc Natl Acad Sci USA 2008 105 36 13427 13432 18765800
  • O’Brien CA Pollett A Gallinger S Dick JE A human colon cancer cell capable of initiating tumour growth in immunodeficient mice Nature 2007 445 7123 106 110 17122772
  • Ferrand A Sandrin MS Shulkes A Baldwin GS Expression of gastrin precursors by CD133-positive colorectal cancer cells is crucial for tumour growth Biochim Biophys Acta 2009 1793 3 477 488 19321126
  • Singh SK Hawkins C Clarke ID Identification of human brain tumour initiating cells Nature 2004 432 7015 396 401 15549107
  • Hilbe W Dirnhofer S Oberwasserlechner F CD133 positive endothelial progenitor cells contribute to the tumour vasculature in non-small cell lung cancer J Clin Pathol 2004 57 9 965 969 15333659
  • Shmelkov SV Butler JM Hooper AT CD133 expression is not restricted to stem cells, and both CD133+ and CD133− metastatic colon cancer cells initiate tumors J Clin Invest 2008 118 6 2111 2120 18497886
  • Lugli A Iezzi G Hostettler I Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44 s, EpCAM, and ALDH1 in colorectal cancer Br J Cancer 2010 103 3 382 390 20606680
  • Horst D Kriegl L Engel J Kirchner T Jung A CD133 expression is an independent prognostic marker for low survival in colorectal cancer Br J Cancer 2008 99 8 1285 1289 18781171
  • Du L Rao G Wang H CD44-positive cancer stem cells expressing cellular prion protein contribute to metastatic capacity in colorectal cancer Cancer Res 2013 73 8 2682 2694 23418321
  • Li CY Li BX Liang Y Higher percentage of CD133+ cells is associated with poor prognosis in colon carcinoma patients with stage IIIB J Transl Med 2009 7 56 63 19583834
  • Crea F Fornaro L Masi G Falcone A Danesi R Farrar W Faithful markers of circulating cancer stem cells: is CD133 sufficient for validation in clinics? J Clin Oncol 2011 29 25 3487 3488 21788560
  • Chu P Clanton DJ Snipas TS Characterization of a subpopulation of colon cancer cells with stem cell-like properties Int J Cancer 2009 124 6 1312 1321 19072981
  • LaBarge MA Bissell MJ Is CD133 a marker of metastatic colon cancer stem cells? J Clin Invest 2008 118 6 2021 2024 18497883
  • Du L Wang H He L CD44 is of functional importance for colorectal cancer stem cells Clin Cancer Res 2008 14 21 6751 6760 18980968
  • Dalerba P Dylla SJ Park IK Phenotypic characterization of human colorectal cancer stem cells Proc Natl Acad Sci USA 2007 104 24 10158 10163 17548814
  • Todaro M Perez Alea M Scopelliti A Medema JP Stassi G IL-4-mediated drug resistance in colon cancer stem cells Cell Cycle 2008 7 3 309 313 18235245
  • Huang EH Hynes MJ Zhang T Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis Cancer Res 2009 69 8 3382 3389 19336570
  • Lohberger B Rinner B Stuendl N Aldehyde dehydrogenase 1, a potential marker for cancer stem cells in human sarcoma PLoS One 2012 7 8 e43664 22928012
  • Garcia VM Batlle JF Casado E Immunohistochemical analysis of tumour regression grade for rectal cancer after neoadjuvant chemoradiotherapy Colorectal Dis 2011 13 9 989 998 20718834
  • Fan LF Dong WG Jiang CQ Xia D Liao F Yu QF Expression of putative stem cell genes Musashi-1 and beta1-integrin in human colorectal adenomas and adenocarcinomas Int J Colorectal Dis 2010 25 1 17 23 19714342
  • Fan X Ouyang N Teng H Yao H Isolation and characterization of spheroid cells from the HT29 colon cancer cell line Int J Colorectal Dis 2011 26 10 1279 1285 21670985
  • Hellsten R Johansson M Dahlman A Sterner O Bjartell A Galiellalactone inhibits stem cell-like ALDH-positive prostate cancer cells PLoS One 2011 6 7 e22118 21779382
  • Singh A Settleman J EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer Oncogene 2010 29 34 4741 4751 20531305
  • Higuchi A Uchiyama S Demura M Enhanced CEA production associated with aspirin in a culture of CW-2 cells on some polymeric films Cytotechnology 1999 31 3 233 242 19003147
  • Zhang J Li H Wang X Phage-derived fully human antibody scFv fragment directed against human vascular endothelial growth factor receptor 2 blocked its interaction with VEGF Biotechnol Prog 2012 28 4 981 989 22581629
  • Alfred R Radford J Fan J Efficient suspension bioreactor expansion of murine embryonic stem cells on microcarriers in serum-free medium Biotechnol Prog 2011 27 3 811 823 21538971
  • Higuchi A Huang SC Shen PY Differentiation ability of amniotic fluid-derived stem cells cultured on extracellular matrix-immobilized surface Curr Nanosci 2011 7 6 893 901
  • Liu JY Peng HF Gopinath S Tian J Andreadis ST Derivation of functional smooth muscle cells from multipotent human hair follicle mesenchymal stem cells Tissue Eng Part A 2010 16 8 2553 2564 20236033
  • Shi B Deng L Shi X The enhancement of neural stem cell survival and growth by coculturing with expanded sertoli cells in vitro Biotechnol Prog 2012 28 1 196 205 22109810
  • Mohr JC de Pablo JJ Palecek SP Electroporation of human embryonic stem cells: small and macromolecule loading and DNA transfection Biotechnol Prog 2006 22 3 825 834 16739967
  • Malpique R Tostões R Beier AFJ Surface-based cryopreservation strategies for human embryonic stem cells: a comparative study Biotechnol Prog 2012 28 4 1079 1087 22718690
  • Aquino A Prete SP Guadagni F Effect of 5-fluorouracil on carcinoembryonic antigen expression and shedding at clonal level in colon cancer cells Anticancer Res 2000 20 5B 3475 3484 11131650
  • Prete SP Rossi L Correale PP Combined effects of protein kinase inhibitors and 5-fluorouracil on CEA expression in human colon cancer cells Pharmacol Res 2005 52 2 167 173 15967383
  • Yan H Chen X Zhang Q Drug-tolerant cancer cells show reduced tumor-initiating capacity: depletion of CD44 cells and evidence for epigenetic mechanisms PLoS One 2011 6 9 e24397 21935404
  • Staab HJ Anderer FA Brümmendorf T Stumpf E Fischer R Prognostic value of preoperative serum CEA level compared to clinical staging. I. colorectal carcinoma Br J Cancer 1981 44 5 652 662 7317270
  • Wolmark N Fisher B Wieand HS The prognostic significance of preoperative carcinoembryonic antigen levels in colorectal cancer. Results from NSABP (National Surgical Adjuvant Breast and Bowel Project) clinical trials Ann Surg 1984 199 4 375 382 6370155
  • Ailawadhi S Sunga A Rajput A Yang GY Smith J Fakih M Chemotherapy-induced carcinoembryonic antigen surge in patients with metastatic colorectal cancer Oncology 2006 70 1 49 53 16446549
  • Fakih MG Padmanabhan A CEA monitoring in colorectal cancer. What you should know Oncology (Williston Park) 2006 20 6 579 587 16773844
  • Sørbye H Dahl O Carcinoembryonic antigen surge in metastatic colorectal cancer patients responding to oxaliplatin combination chemotherapy: implications for tumor marker monitoring and guidelines J Clin Oncol 2003 21 23 4466 4467 14645446