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Review

TNF-α inhibitors: are they carcinogenic?

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Pages 241-247 | Published online: 06 Dec 2010

References

  • BoymanOHeftiHPConradCNickoloffBSuterMNestleFOSpontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor αJ Exp Med200419973173614981113
  • O’ByrneKJDalgleishAGChronic immune activation and inflammation as the cause of malignancyBr J Cancer20018547348311506482
  • KimREmiMTanabeKCancer immunoediting from immune surveillance to immune escapeImmunology2000121114
  • YounesAAggarwallBBClinical Implications of the tumor necrosis factor family in benign and malignant hematologic disordersCancer20039845846712879461
  • JohrerKJankeKKrugmannJFieglMGreilRTransendothelial migration of myeloma cells is increased by tumor necrosis factor (TNF)-alpha via TNF receptor 2 and autocrine upregulation of MCP-1Clin Cancer Res2004101901191015041705
  • BergeronSBeaucheminMBertrandRCamptothecin and etoposide induced apoptosis in human leukemia cells is independent of cell death receptor 4 and 4 aggregation but accelerates tumor necrosis factor related apoptosis inducing ligand mediated cell deathMol Cancer Ther200431659166915634660
  • LeeNSCheongHJKimSJEx vivo purging of leukemia cells using tumor necrosis factor related apoptosis inducing ligand in hematopoietic stem cell transplantationLeukemia2003171375138312835727
  • Beyne-RauzyORecherCDastugueNTumor necrosis factor alpha induces senescence and chromosomal instability in human leukemic cellsOncogene2004237507751615326480
  • BaudVKarinMSignal transduction by tumor necrosis factor and its relativesTrendsCell Biol200111372377
  • AshkenaziATargeting death and decoy receptors of the tumour-necrosis factor superfamilyNat Rev Cancer2002242043012189384
  • SilmanAJPetrieJHazlemanBEvansSJLymphoproliferative cancer and other malignancy in patients with rheumatoid arthritis treated with azathioprine: a 20 year follow up studyAnn Rheum Dis1988479889923207388
  • RadisCDKahlLEBakerGLEffect of cyclophosphamide on the development of malignancy and on long-term survival of patients with rheumatoid arthritis: a 20 year followup studyArthritis Rheum199538112011277639809
  • MarietteXCazals-HatemDWarszawkiJLioteFBalandraudNSibiliaJLymphomas in rheumatoid arthritis patients treated with methotraxate: a 3 year prospective study in FranceBlood2002993909391512010788
  • LipskyPEvan der HeijdeDMSt ClairEWfor the Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study GroupInfliximab and methotraxate in the treatment of rheumatoid arthritisN Engl J Med20003431594160211096166
  • TsimberidouAMGilesFJDuvicMKurzrockRPilot study of etanercept in patients with relapsed cutaneous T-cell lymphomasJ Am Acad Dermatol20045120020415280837
  • TsimberidouAMWaddelowTKantarjianHMAlbitarMGilesFJPilot study of recombinant human soluble tumor necrosis factor (TNF) receptor (p75) fusion protein (TNFR:Fc; Enbrel) in patients with refractory multiple myeloma: increase in plasma TNFα levels during treatmentLeuk Res20032737538012620287
  • KaneSAltschulerEKastRECrohn’s disease remission on bupropionGastroenterology20011211260126111706830
  • BaecklundEEkbomASparenPFelteliusNKlareskogLDisease activity and risk of lymphoma in patients with rheumatoid arthritis: a nested case – control studyBMJ19983171801819665898
  • ThomasEBrewsterDHBlackRJMacfarlaneGJRisk of malignancy among patients with rheumatic conditionsInt J Cancer20008849750211054684
  • BernsteinCNBlanchardJFKliewerEWajdaACancer risk in patients with inflammatory bowel disease: a population based studyCancer20019185486211241255
  • BrownSLGreeneMHGreshonSKEdwardsETBraunMMTumor necrosis factor antagonist therapy and lymphoma development. Twenty six cases reported to the Food and Drug AdministrationArthritis Rheum2002463151315812483718
  • OutlawWFleischerABloomfeldRLymphomatoid papulosis in a patient with Crohn’s disease treated with infliximabInflamm Bowel Dis20091596596618798565
  • WolfeFMichaudKLymphoma in rheumatoid arthritis: the effect of methotraxate and anti-tumor necrosis factor therapy in 18,572 patientsArthritis Rheum20045061740175115188349
  • BaecklundESundstromCEkbomALymphoma subtypes in patients with rheumatoid arthritis: increased proportion of diffuse large B cell lymphomaArthritis Rheum2003481543155012794821
  • GeborekPBladstromATuressonCTumour necrosis factor blockers do not increase overall tumour risk in patients with rheumatoid arthritis, but may be associated with an increased risk of lymphomasAnn Rheum Dis20056469970315695534
  • LeombrunoJPEinarsonTRKeystoneECThe safety of anti-tumour necrosis factor treatments in rheumatoid arthritis: meta and exposure-adjusted pooled analyses of serious adverse eventsAnn Rheum Dis2009681136114518753157
  • NairBRavalGMehtaPTNF-alpha inhibitor etanercept and hematologic malignancies: report of a case and review of literatureAm J Hematol2007821022102417654504
  • BaklandGNossentHAcute myelogenous leukemia following etanercept therapyRheumatology20034290090112826706
  • SabaNSKosseifiSGCharafEAAdalimumab-induced acute myelogenous leukemiaSouth Med J20081011261126219005432
  • Wegener’s Granulomatosis Etanercept Trial (WGET) Research GroupEtanercept plus standard therapy for Wegener’s granulomatosisN Engl J Med200535136115673801
  • De VriesHSvan OijenMGde JongDJSerious events with infliximab in patients with inflammatory bowel disease: a 9 year cohort study in the NetherlandsDrug Saf2008311135114419026030
  • St ClairEWvan der HeijdeDMSmolenJSCombination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized controlled trialArthritis Rheum200450113432344315529377
  • KeystoneECKavanaughAFSharpJTRadiographic, clinical, and functional outcomes of treatment with adalimiumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotraxate therapy: a randomized placebo controlled 52 week trialArthritis Rheum2004501400141115146409
  • van de PutteLBAAtkinsCMalaiseMEfficacy and safety of adalimumab as monotherapy in patients with rheumatoid arthritis for whom previous disease modifying antirheumatic drug treatment has failedAnn Rheum Dis20046350851615082480
  • BongartzTSuttonASweetingMBuchanIMattesonEMontoriVAnti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies. Systematic review and meta-analysis of rare harmful effects in randomized controlled trialsJAMA20062952275228516705109
  • WolfeFMichaudKBiologic treatment of rheumatoid arthritis and the risk of malignancy. Analyses from a large US observational studyArthritis Rheum2007562886289517729297
  • BianconeLOrlandoAKohnAInfliximab and newly diagnosed neoplasia in Crohn’s disease: a multicentre matched pair studyGut20065522823316120759
  • LichtensteinGRCohenRDFeagenBGSafety of infliximab and other Crohn’s disease therapies – TREAT registry data with nearly 15,000 patient-years of follow-upGastroenterology2006130A71
  • LeesCWAliAIThompsonAIThe safety profile of anti-tumour necrosis factor therapy in inflammatory bowel disease in clinical practice: analysis of 620 patient years follow upAliment Pharmacol Ther20092928629719132970
  • ColombelJFLoftusEVJrThe safety profile on infliximab in patients with Crohn’s disease: the Mayo clinic experience in 500 patientsGastroenterology2004126193114699483
  • RennardSIFogartyCKelsenSThe safety and efficacy of infliximab in moderate to severe chronic obstructive pulmonary diseaseAm J Respir Crit Care Med200717592693417290043
  • LeesCWIronsideJWallaceWASatsangiJResolution of non small cell lung cancer after withdrawal of anti-TNF therapyN Engl J Med200853932032118635444
  • ShaoLMChenMYCaiJTMeta-analysis: the efficacy and safety of certolizumab pegol in Crohn’s diseaseAliment Pharmacol Ther20092960561419183161
  • SandbornWJFeaganBGStoinovSCertolizumab pegol for the treatment of Crohn’s diseaseN Engl J Med200735722823817634458
  • SinghJANoorbaloochiSSinghGGolimumab for rheumatoid arthritis: a systematic reviewJ Rheumatol2010371096110420436075
  • StorageSSAgrawalHFurstDEDescription of the efficacy and safety of three new biologics in the treatment of rheumatoid arthritisKorean J Internal Med20102511720195397
  • SmithKJSkeltonHGRapid onset of cutaneous squamous cell carcinoma in patients with rheumatoid arthritis after starting tumor necrosis factor alpha receptor IgG1-Fc fusion complex therapyJ Am Acad Dermatol20014595395611712048
  • EssarACArbilAFayneSDoyleJAAcute development of multiple keratoacanthomas and squamous cell carcinomas after treatment with infliximabJ Am Acad Dermatol200450Suppl 5S75S7715097933
  • BurgeDEtanercept and squamous cell carcinomaJ Am Acad Dermatol20034935835912894101
  • LebwohlMBlumRBerkowitzENo evidence of increased risk of squamous cell carcinoma in patients with rheumatoid arthritis receiving etanercept for up to 5 yearsArch Dermatol200514186186416027301
  • ChakravartyEFMichaudKWolfeFSkin cancer, rheumatoid arthritis, and tumor necrosis factor inhibitorsJ Rheumatol2005322130213516265690
  • LedinghamJDeightonCUpdate of the British Society of Rheumatology: guidelines for prescribing TNF blockers in adults with rheumatoid arthritis (update of previous guidelines of April 2001)Rheumatology20054415716315637039
  • SaagKGTengGGPatkarNMfor the American College of RheumatologyAmerican College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying anti rheumatic drugs in rheumatoid arthritisArthritis Rheum20085976278418512708