Early effects of roflumilast on insulin sensitivity in adults with prediabetes and overweight/obesity involve age-associated fat mass loss – results of an exploratory study

Ijeoma M Muo1 Laboratory of Obesity and Aging Research NHLBI, National Institutes of Health, Bethesda, MD 20892, USA, [email protected], [email protected]Correspondence[email protected]

Sandra D MacDonald2 NHLBI Pulmonary Branch, Laboratory of Chronic Airway Infections, National Institutes of Health, Bethesda, MD 20892, USA

Ritu Madan3 Diabetes Endocrinology and Obesity Branch, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA

Sung-Jun Park1 Laboratory of Obesity and Aging Research NHLBI, National Institutes of Health, Bethesda, MD 20892, USA, [email protected], [email protected]

Ahmed M Gharib4 Biomedical and Metabolic Imaging Branch NIDDK, National Institutes of Health, Bethesda, MD 20892, USA

Pedro E Martinez5 Section on Behavioral Endocrinology, NIMH, National Institutes of Health, Bethesda, MD 20892, USA

Mary F Walter3 Diabetes Endocrinology and Obesity Branch, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA

Shanna B Yang6 Clinical Center Nutrition Department, National Institutes of Health, Bethesda, MD 20892, USA

Justin A Rodante7 Laboratory of Inflammation and Cardiometabolic Diseases, NHLBI, National Institutes of Health, Bethesda, MD 20892, USA

Amber B Courville6 Clinical Center Nutrition Department, National Institutes of Health, Bethesda, MD 20892, USA

Peter J Walter8 Mass Spectrometry Clinical Core, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA

Hongyi Cai8 Mass Spectrometry Clinical Core, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA

Michael Glicksman3 Diabetes Endocrinology and Obesity Branch, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA

Gioia M Guerrieri5 Section on Behavioral Endocrinology, NIMH, National Institutes of Health, Bethesda, MD 20892, USA

Rivka R Ben-Dor9 NIMH, National Institutes of Health, Bethesda, MD 20892, USA

Ronald Ouwerkerk4 Biomedical and Metabolic Imaging Branch NIDDK, National Institutes of Health, Bethesda, MD 20892, USA

Stephanie Mao1 Laboratory of Obesity and Aging Research NHLBI, National Institutes of Health, Bethesda, MD 20892, USA, [email protected], [email protected]

Jay H Chung1 Laboratory of Obesity and Aging Research NHLBI, National Institutes of Health, Bethesda, MD 20892, USA, [email protected], [email protected]Correspondence[email protected]

References