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Original Research

Telmisartan is effective to ameliorate metabolic syndrome in rat model – a preclinical report

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Pages 901-911 | Published online: 07 Dec 2018

References

  • Srikanthan K Feyh A Visweshwar H Shapiro JI Sodhi K Systematic review of metabolic syndrome biomarkers: a panel for early detection, management, and risk stratification in the West Virginian population Int J Med Sci 2016 13 1 25 38 26816492
  • Misra A Singhal N Khurana L Obesity, the metabolic syndrome, and type 2 diabetes in developing countries: role of dietary fats and oils J Am Coll Nutr 2010 29 3 Suppl 289S 301S 20823489
  • Engin A The definition and prevalence of obesity and metabolic syndrome Adv Exp Med Biol 2017 960 1 17 28585193
  • Lakka HM Laaksonen DE Lakka TA The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men JAMA 2002 288 21 2709 2716 12460094
  • Hassannejad R Kazemi I Sadeghi M Longitudinal association of metabolic syndrome and dietary patterns: a 13-year prospective population-based cohort study Nutr Metab Cardiovasc Dis 2018 28 4 352 360 29458993
  • Shankar E Vykhovanets EV Vykhovanets OV High-fat diet activates pro-inflammatory response in the prostate through association of Stat-3 and NF-kappaB Prostate 2012 72 3 233 243 21604287
  • Ferrannini E Natali A Capaldo B Lehtovirta M Jacob S Yki-Jarvinen H Insulin resistance, hyperinsulinemia, and blood pressure: role of age and obesity. European Group for the Study of Insulin Resistance (EGIR) Hypertension 1997 30(5 1144 1149 9369268
  • Chen J Gu D Huang J Metabolic syndrome and salt sensitivity of blood pressure in non-diabetic people in China: a dietary intervention study Lancet 2009 373 9666 829 835 19223069
  • Zhou MS Schulman IH Zeng Q Link between the renin-angiotensin system and insulin resistance: implications for cardiovascular disease Vasc Med 2012 17 5 330 341 22814999
  • Muller-Fielitz H Hubel N Mildner M Vogt FM Barkhausen J Raasch W Chronic blockade of angiotensin AT(1) receptors improves cardinal symptoms of metabolic syndrome in diet-induced obesity in rats Br J Pharmacol 2014 171 3 746 760 24490862
  • Tyagi S Gupta P Saini AS Kaushal C Sharma S The peroxisome proliferator-activated receptor: a family of nuclear receptors role in various diseases J Adv Pharm Technol Res 2011 2 4 236 240 22247890
  • Kramer DK Al-Khalili L Guigas B Leng Y Garcia-Roves PM Krook A Role of AMP kinase and PPARdelta in the regulation of lipid and glucose metabolism in human skeletal muscle J Biol Chem 2007 282 27 19313 19320 17500064
  • Tanaka T Yamamoto J Iwasaki S Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome Proc Natl Acad Sci U S A 2003 100 26 15924 15929 14676330
  • Toral M Gomez-Guzman M Jimenez R Chronic peroxisome proliferator-activated receptorbeta/delta agonist GW0742 prevents hypertension, vascular inflammatory and oxidative status, and endothelial dysfunction in diet-induced obesity J Hypertens 2015 33 9 1831 1844 26147382
  • Kakuta H Sudoh K Sasamata M Yamagishi S Telmisartan has the strongest binding affinity to angiotensin II type 1 receptor: comparison with other angiotensin II type 1 receptor blockers Int J Clin Pharmacol Res 2005 25 1 41 46 15864875
  • Li L Luo Z Yu H Telmisartan improves insulin resistance of skeletal muscle through peroxisome proliferator-activated receptor-delta activation Diabetes 2013 62 3 762 774 23238297
  • Shinohara T Takahashi N Abe I Telmisartan effectively improves insulin sensitivity in hypertensive patients with insulin resistance Obes Res Clin Pract 2011 5(4 e267 360
  • Sanchez RA Masnatta LD Pesiney C Fischer P Ramirez AJ Telmisartan improves insulin resistance in high renin nonmodulating salt-sensitive hypertensives J Hypertens 2008 26 12 2393 2398 19008718
  • Wong SK Chin KY Suhaimi FH Fairus A Ima-Nirwana S Animal models of metabolic syndrome: a review Nutr Metab (Lond) 2016 13 65 27708685
  • Thirunavukkarasu V Anitha Nandhini AT Anuradha CV Lipoic acid attenuates hypertension and improves insulin sensitivity, kallikrein activity and nitrite levels in high fructose−fed rats J Comp Physiol B 2004 174 8 587 592 15565449
  • Ghibaudi L Cook J Farley C van Heek M Hwa JJ Fat intake affects adiposity, comorbidity factors, and energy metabolism of spraguedawley rats Obes Res 2002 10 9 956 963 12226145
  • Zhuhua Z Zhiquan W Zhen Y A novel mice model of metabolic syndrome: the high-fat-high-fructose diet-fed ICR mice Exp Anim 2015 64 4 435 442 26134356
  • Panchal SK Brown L Rodent models for metabolic syndrome research J Biomed Biotechnol 2011 2011 35 1982
  • Van den Bergh A Vanderper A Vangheluwe P Dyslipidaemia in type II diabetic mice does not aggravate contractile impairment but increases ventricular stiffness Cardiovasc Res 2008 77 2 371 379 18006491
  • Mark AL Shaffer RA Correia ML Morgan DA Sigmund CD Haynes WG Contrasting blood pressure effects of obesity in leptin-deficient ob/ob mice and agouti yellow obese mice J Hypertens 1999 17 12 Pt 2 1949 1953 10703894
  • Dong YF Liu L Kataoka K Aliskiren prevents cardiovascular complications and pancreatic injury in a mouse model of obesity and type 2 diabetes Diabetologia 2010 53 1 180 191 19894030
  • Shin SJ Lim JH Chung S Peroxisome proliferator-activated receptor-alpha activator fenofibrate prevents high-fat diet-induced renal lipotoxicity in spontaneously hypertensive rats Hypertens Res 2009 32 10 835 845 19644507
  • Geer EB Islam J Buettner C Mechanisms of glucocorticoid-induced insulin resistance: focus on adipose tissue function and lipid metabolism Endocrinol Metab Clin North Am 2014 43 1 75 102 24582093
  • Chen J Huang XF Shao R Chen C Deng C Molecular mechanisms of antipsychotic drug-induced diabetes Front Neurosci 2017 11 643 29209160
  • Dobrian AD Schriver SD Lynch T Prewitt RL Effect of salt on hypertension and oxidative stress in a rat model of diet-induced obesity Am J Physiol Renal Physiol 2003 285(4 F619 628 12799306
  • Kaur G Meena C Amelioration of obesity, glucose intolerance, and oxidative stress in high-fat diet and low-dose streptozotocin-induced diabetic rats by combination consisting of “curcumin with piperine and quercetin” ISRN Pharmacol 2012 2012 957283 22474599
  • Suman RK Ray Mohanty I Borde MK Maheshwari U Deshmukh YA Development of an experimental model of diabetes co-existing with metabolic syndrome in rats Adv Pharmacol Sci 2016 2016 9463476 26880906
  • Li YX Cheng KC Asakawa A Role of musclin in the pathogenesis of hypertension in rat PLoS One 2013 8 8 e72004 23940802
  • Bowe JE Franklin ZJ Hauge-Evans AC King AJ Persaud SJ Jones PM Metabolic phenotyping guidelines: assessing glucose homeostasis in rodent models J Endocrinol 2014 222 3 G13 25 25056117
  • Kuo SC Chung HH Huang CH Cheng JT Decrease of hyperglycemia by syringaldehyde in diabetic rats Horm Metab Res 2014 46 1 8 13 23918689
  • Araki K Masaki T Katsuragi I Tanaka K Kakuma T Yoshimatsu H Telmisartan prevents obesity and increases the expression of uncoupling protein 1 in diet-induced obese mice Hypertension 2006 48 1 51 57 16717145
  • Fujisaka S Usui I Kanatani Y Telmisartan improves insulin resistance and modulates adipose tissue macrophage polarization in high-fat-fed mice Endocrinology 2011 152 5 1789 1799 21427223
  • Choi GJ Kim HM Kang H Kim J Effects of telmisartan on fat distribution: a meta-analysis of randomized controlled trials Curr Med Res Opin 2016 32 7 1303 1309 27010868
  • He H Yang D Ma L Telmisartan prevents weight gain and obesity through activation of peroxisome proliferator-activated receptor-delta-dependent pathways Hypertension 2010 55 4 869 879 20176998
  • Khan AH Imig JD Telmisartan provides better renal protection than valsartan in a rat model of metabolic syndrome Am J Hypertens 2011 24 7 816 821 21415842
  • Vitale C Mercuro G Castiglioni C Metabolic effect of telmisartan and losartan in hypertensive patients with metabolic syndrome Cardiovasc Diabetol 2005 4 6 15892894
  • Michel MC Bohner H Koster J Schafers R Heemann U Safety of telmisartan in patients with arterial hypertension: an open-label observational study Drug Saf 2004 27 5 335 344 15061687
  • Cooper ME Tikellis C Thomas MC Preventing diabetes in patients with hypertension: one more reason to block the renin-angiotensin system J Hypertens Suppl 2006 24 1 S57 63 16601575
  • Jandeleit-Dahm KA Tikellis C Reid CM Johnston CI Cooper ME Why blockade of the renin-angiotensin system reduces the incidence of new-onset diabetes J Hypertens 2005 23 3 463 473 15716683
  • Schuchard J Winkler M Stolting I Lack of weight gain after angiotensin AT1 receptor blockade in diet-induced obesity is partly mediated by an angiotensin-(17)/Mas-dependent pathway Br J Pharmacol 2015 172 15 3764 3778 25906670
  • Oron-Herman M Sela BA Rosenthal T Risk reduction therapy for syndrome X: comparison of several treatments Am J Hypertens 2005 18 3 372 378 15797656
  • Zorad S Dou JT Benicky J Long-term angiotensin II AT1 receptor inhibition produces adipose tissue hypotrophy accompanied by increased expression of adiponectin and PPARgamma Eur J Pharmacol 2006 552 1–3 112 122 17064684
  • Chen ZC Lee KS Chen LJ Wang LY Niu HS Cheng JT Cardiac peroxisome proliferator-activated receptor delta (PPARdelta) as a new target for increased contractility without altering heart rate PLoS One 2013 8 5 e64229 23724037
  • Angione AR Jiang C Pan D Wang YX Kuang S PPARdelta regulates satellite cell proliferation and skeletal muscle regeneration Skelet Muscle 2011 1 1 33 22040534
  • Perlstein TS Henry RR Mather KJ Effect of angiotensin receptor blockade on insulin sensitivity and endothelial function in abdominally obese hypertensive patients with impaired fasting glucose Clin Sci (Lond) 2012 122 4 193 202 21861845
  • Wei Y Sowers JR Nistala R Angiotensin II-induced NADPH oxidase activation impairs insulin signaling in skeletal muscle cells J Biol Chem 2006 281 46 35137 35146 16982630
  • Wang YX Zhang CL Yu RT Regulation of muscle fiber type and running endurance by PPARdelta PLoS Biol 2004 2 10 e294 15328533
  • Liu S Hatano B Zhao M Role of peroxisome proliferator-activated receptor {delta}/{beta} in hepatic metabolic regulation J Biol Chem 2011 286 2 1237 1247 21059653
  • Hermida RC Chayan L Ayala DE Association of metabolic syndrome and blood pressure nondipping profile in untreated hypertension Am J Hypertens 2009 22 3 307 313 19131935
  • Weinberger MH Miller JZ Luft FC Grim CE Fineberg NS Definitions and characteristics of sodium sensitivity and blood pressure resistance Hypertension 1986 8 6 Pt 2 II127 134 3522418
  • Uetake Y Ikeda H Irie R High-salt in addition to high-fat diet may enhance inflammation and fibrosis in liver steatosis induced by oxidative stress and dyslipidemia in mice Lipids Health Dis 2015 14 6 25888871
  • Lenda DM Boegehold MA Effect of a high-salt diet on oxidant enzyme activity in skeletal muscle microcirculation Am J Physiol Heart Circ Physiol 2002 282 2 H395 402 11788385
  • Nickenig G Strehlow K Roeling J Zolk O Knorr A Bohm M Salt induces vascular AT1 receptor overexpression in vitro and in vivo Hypertension 1998 31 6 1272 1277 9622141
  • Sueta D Koibuchi N Hasegawa Y Telmisartan exerts sustained blood pressure control and reduces blood pressure variability in metabolic syndrome by inhibiting sympathetic activity Am J Hypertens 2014 27 12 1464 1471 24871627
  • Peng J Zhao Y Zhang H Prevention of metabolic disorders with telmisartan and indapamide in a Chinese population with high-normal blood pressure Hypertens Res 2015 38 2 123 131 25273554
  • Yuen CY Wong WT Tian XY Telmisartan inhibits vasoconstriction via PPARgamma-dependent expression and activation of endothelial nitric oxide synthase Cardiovasc Res 2011 90 1 122 129 21156825