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Diabetes, Metabolic Syndrome and Obesity Volume 12, 2019 - Issue
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Original Research

The Role Of Adiponectin, TNF-α And Glutathione In The Pathogenesis And Evolution Of Type 1 Diabetes

Csilla Enikő Szabo1 Department of Pediatrics I, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania;2 Pediatric Clinic I, Pediatric Emergency Hospital, Cluj-Napoca, RomaniaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-2568-6312
ORCID Icon,
Roxana Flavia Ilieș3 Department of Medical Genetics, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
,
Casian Simon Aioanei3 Department of Medical Genetics, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
,
Andreea Catana3 Department of Medical Genetics, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
,
Victoria Creț2 Pediatric Clinic I, Pediatric Emergency Hospital, Cluj-Napoca, RomaniaORCID Iconhttps://orcid.org/0000-0002-7873-5993
ORCID Icon,
Radu Sorin Șerban1 Department of Pediatrics I, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania;2 Pediatric Clinic I, Pediatric Emergency Hospital, Cluj-Napoca, RomaniaORCID Iconhttps://orcid.org/0000-0002-8563-0591
ORCID Icon &
Ioan Victor Pop3 Department of Medical Genetics, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj Napoca, Romania
 show all
Pages 2303-2308 | Published online: 05 Nov 2019

References

  • Bekris LM , Shephard C , Peterson M , et al. Glutathione-s-transferase M1 and T1 polymorphisms and associations with type 1 diabetes age-at-onset. Autoimmunity . 2005;38(8):567–575.16390810
  • Atkinson MA , Maclaren NK . The pathogenesis of insulin-dependent diabetes mellitus. N Engl J Med . 1994;331:1428. doi:10.1056/NEJM199411243312107 7969282
  • Imagawa A , Funahashi T , Nakamura T , et al. Elevated serum concentration of adipose-derived factor, adiponectin, in patients with type 1 diabetes. Diabetes Care . 2002;25(9):1665–1666. doi:10.2337/diacare.25.9.1665 12196453
  • Zhang D , Efendic S , Brismar K , Gu HF . Effects of MCF2L2, ADIPOQ and SOX2 genetic polymorphisms on the development of nephropathy in type 1 diabetes Mellitus. BMC Med Genet . 2010;11(1):116. doi:10.1186/1471-2350-11-116 20667095
  • Mojiminiyi OA , Abdella NA , Al Arouj M , Ben Nakhi A . Adiponectin, insulin resistance and clinical expression of the metabolic syndrome in patients with Type 2 diabetes. Int J Obes (Lond) . 2007;31(2):213–220. Epub 2006 Jun 6. doi:10.1038/sj.ijo.0803355 16755284
  • Ouedraogo R , Gong Y , Berzins B , et al. Adiponectin deficiency increases leukocyte-endothelium interactions via upregulation of endothelial cell adhesion molecules in vivo. J Clin Invest . 2007;117(6):1718–1726. doi:10.1172/JCI29623 17549259
  • Ohashi K , Ouchi N , Matsuzawa Y . Anti-inflammatory and antiatherogenic properties of adiponectin. Biochimie . 2012;94:2137–2142. doi:10.1016/j.biochi.2012.06.008 22713764
  • Lechleitner M , Koch T , Herold M , Dzien A , Hoppichler F . Tumour necrosis factor-alpha plasma level in patients with type 1 diabetes mellitus and its association with glycaemic control and cardiovascular risk factors. Journal of Internal Medicine . 2000;248(1):67–76. doi:10.1046/j.1365-2796.2000.00705.x 10947883
  • Mayer-Davis EJ , Kahkoska AR , Jefferies C , et al. ISPAD clinical practice consensus guidelines 2018: definition, epidemiology, and classification of diabetes in children and adolescents. Pediatr Diabetes . 2018;19(Suppl 27):7. doi:10.1111/pedi.2018.19.issue-S27
  • American Diabetes Association Classification and Diagnosis of Diabetes. Diabetes Care . 2017;40(Suppl1):S11–S24. doi:10.2337/dc17-S005 27979889
  • Bostrom MA , Freedman BI , Langefeld CD , et al. Association of adiponectin gene polymorphisms with type 2 diabetes in an African American population enriched for nephropathy. Diabetes . 2009;58(2):499–504. doi:10.2337/db08-0598 19056609
  • Galler A , Gelbrich G , Kratzsch J , Noack N , Kapellen T , Kiess W . Elevated serum levels of adiponectin in children, adolescents and young adults with type 1 diabetes and the impact of age, gender, body mass index and metabolic control: a longitudinal study. Eur J Endocrinol . 2007;157(4):481–489. doi:10.1530/EJE-07-0250 17893263
  • Frystyk J , Tarnow L , Krarup Hansen T , Parving -H-H , Flyvbjerg A . Increased serum adiponectin levels in type 1 diabetic patients with microvascular complications. Diabetologia . 2005;48(9):1911–1918. doi:10.1007/s00125-005-1850-z 16078018
  • Bid HK , Konwar R , Saxena M , Chaudhari P , Agrawal CG , Banerjee M . Association of glutathione S-transferase (GSTM1, T1 and P1) gene polymorphisms with type 2 diabetes mellitus in north Indian population. J Postgrad Med . 2010;56(3):176–181. doi:10.4103/0022-3859.68633 20739761
  • Vojtková J , Ďurdík P , Čiljaková M , Michnová Z , Turčan T , Babušíková E . The association between glutathione S-transferase T1 and M1 gene polymorphisms and cardiovascular autonomic neuropathy in Slovak adolescents with type 1 diabetes mellitus. J Diabetes Complications . 2013;27(1):44–48. doi:10.1016/j.jdiacomp.2012.07.002 23021798
  • Barseem N , Elsamalehy M . Gene polymorphisms of glutathione S-Transferase T1/M1 in Egyptian children and adolescents with Type 1 diabetes mellitus. J Clin Res Pediatr Endocrinol . 2017;9(2):138–143. doi:10.4274/jcrpe.3690 27908841
  • Vojtková J , Durdík P , Ciljaková M , Michnová Z , Turcan T , Babusíková E . The association between gene polymorphisms of glutathione S-transferase T1/M1 and type 1 diabetes in Slovak children and adolescents. Cent Eur J Public Health . 2013;21(2):88–91. doi:10.21101/cejph.a3807 24053064
  • Allam G , Nasr A , Talaat IM , et al. Association between cytokine genes polymorphisms and type 1 diabetes: a case-control study on Saudi population. Immunological Investigations . 2018;47(3):229–240. doi:10.1080/08820139.2017.1416398 29257900

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