Evaluation of Antidiabetic Effect of Ethanolic Leaves Extract of Becium grandiflorum Lam. (Lamiaceae) in Streptozotocin-Induced Diabetic Mice

References

• Ross SA, Gulve EA, Wang M. Chemistry and biochemistry of type 2 diabetes. Chem Rev. 2004;104(3):1255–1282. doi:10.1021/cr0204653
   PubMed Web of Science ®Google Scholar
• Edwin E, Sheeja E, Dhanabal S, Suresh B. Antihyperglycemic activity of Passiflora mollissima Bailey. Indian J Pharm Sci. 2007;69(4):570. doi:10.4103/0250-474X.36947
   Google Scholar
• Oyedemi S, Yakubu M, Afolayan A. Antidiabetic activities of aqueous leaves extract of Leonotis leonurus in streptozotocin induced diabetic rats. J Med Plant Res. 2011;5(1):119–125.
   Google Scholar
• Cho N, Shaw J, Karuranga S, et al. IDF Diabetes Atlas: global estimates of diabetes prevalence for 2017 and projections for 2045. Diabetes Res Clin Pract. 2018;138:271–281. doi:10.1016/j.diabres.2018.02.023
   PubMed Web of Science ®Google Scholar
• Guariguata L, Whiting DR, Hambleton I, Beagley J, Linnenkamp U, Shaw JE. Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res Clin Pract. 2014;103(2):137–149. doi:10.1016/j.diabres.2013.11.002
   PubMed Web of Science ®Google Scholar
• Shanker K, Naradala J, Mohan GK, Kumar G, Pravallika P. A sub-acute oral toxicity analysis and comparative in vivo anti-diabetic activity of zinc oxide, cerium oxide, silver nanoparticles, and Momordica charantia in streptozotocin-induced diabetic Wistar rats. RSC Adv. 2017;7(59):37158–37167. doi:10.1039/C7RA05693A
   Web of Science ®Google Scholar
• Chávez-Silva F, Cerón-Romero L, Arias-Durán L, et al. Antidiabetic effect of Achillea millefollium through multitarget interactions: α-glucosidases inhibition, insulin sensitization and insulin secretagogue activities. J Ethnopharmacol. 2018;212:1–7. doi:10.1016/j.jep.2017.10.005
   PubMedGoogle Scholar
• Chimere U, Arome O, Affiong E, Ogechukwu A, Ike C. Anti-diabetic effect of the methanolic leaf extract of Axonopus compressus (P. Beauv) in Alloxan Induced Diabetic Rats. Int J Biochem Res Rev. 2016;12(1):1–5. doi:10.9734/IJBCRR/2016/25425
   Google Scholar
• Whiting DR, Guariguata L, Weil C, Shaw J. IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Res Clin Pract. 2011;94(3):311–321. doi:10.1016/j.diabres.2011.10.029
   PubMed Web of Science ®Google Scholar
• Atlas D. International Diabetes Federation. IDF Diabetes Atlas. 7th ed. Brussels, Belgium: International Diabetes Federation; 2015.
   Google Scholar
• Yazew KG, Walle TA, Azagew AW. Prevalence of anti-diabetic medication adherence and determinant factors in Ethiopia: a systemic review and meta-analysis, 2019. Int J Afr Nurs Sci. 2019;11:100167. doi:10.1016/j.ijans.2019.100167
   Google Scholar
• Tafesse TB, Hymete A, Mekonnen Y, Tadesse M. Antidiabetic activity and phytochemical screening of extracts of the leaves of Ajuga remota Benth on alloxan-induced diabetic mice. BMC Complement Altern Med. 2017;17(1):243. doi:10.1186/s12906-017-1757-5
   PubMed Web of Science ®Google Scholar
• Robinson MM, Zhang X. Traditional medicines: global situation, issues and challenges. World Med Situation. 2011;1–14.
   Google Scholar
• Mihailova S, Tsvetkova A, Todorova A. Pharmacological trends in the treatment of diabetes type 2-New classes of antidiabetic drugs. Int Arch Integr Med. 2015;2(4):223–228.
   Google Scholar
• Gebremeskel L, Bhoumik D, Sibhat GG, Tuem KB. In vivo wound healing and anti-inflammatory activities of leaf latex of aloe megalacantha baker (Xanthorrhoeaceae). Evid Based Complement Alternat Med. 2018;2018:1–7. doi:10.1155/2018/5037912
   Google Scholar
• Tesfaye A, Makonnen E, Gedamu S. Hypoglycemic and antihyperglycemic activity of aqueous extract of Justicia Schimperiana leaves in normal and streptozotocin-induced diabetic mice. Int J Pharma Sci Res. 2016;7(2):110–113.
   Google Scholar
• Toma A, Makonnen E, Mekonnen Y, Debella A, Adisakwattana S. Antidiabetic activities of aqueous ethanol and n-butanol fraction of Moringa stenopetala leaves in streptozotocin-induced diabetic rats. BMC Complement Altern Med. 2015;15(1):242. doi:10.1186/s12906-015-0779-0
   PubMed Web of Science ®Google Scholar
• Beshir K, Shibeshi W, Ejigu A, Engidawork E. In-vivo wound healing activity of 70% ethanol leaf extract of Beciumgrandiflorum Lam. (Lamiaceae) in mice. Ethiop Pharm J. 2016;32:117–130. doi:10.4314/epj.v32i2.3
   Google Scholar
• Burger I, Burger BV, Albrecht CF, Spies HS, Sándor P. Triterpenoid saponins from Becium grandiflorum var. obovatum. Phytochemistry. 1998;49(7):2087–2095. doi:10.1016/S0031-9422(98)00413-0
   PubMedGoogle Scholar
• Somasundaram G, Manimekalai K, Salwe KJ, Pandiamunian J. Evaluation of the antidiabetic effect of Ocimum sanctum in type 2 diabetic patients. Int J Life Sci Pharm Res. 2012;5:75–81.
   Google Scholar
• Teklehaymanot T, Giday M, Medhin G, Mekonnen Y. Knowledge and use of medicinal plants by people around Debre Libanos monastery in Ethiopia. J Ethnopharmacol. 2007;111(2):271–283. doi:10.1016/j.jep.2006.11.019
   PubMed Web of Science ®Google Scholar
• Teklay A, Abera B, Giday M. An ethnobotanical study of medicinal plants used in Kilte Awulaelo District, Tigray Region of Ethiopia. J Ethnobiol Ethnomed. 2013;9(1):65. doi:10.1186/1746-4269-9-65
   PubMed Web of Science ®Google Scholar
• Equar G, Gebremedhin G, Gebrekidan A, Asmelash T, Yirga G. Determination of antimicrobial activity and phytochemical screening of selected medicinal plants in Tigray region of Northern Ethiopia. Momona Ethiop j Sci. 2018;10(2):255–270. doi:10.4314/mejs.v10i2.6
   Google Scholar
• Kolb H. Mouse models of insulin dependent diabetes: low‐dose streptozocin‐induced diabetes and nonobese diabetic (NOD) mice. Diabetes Metab Rev. 1987;3(3):751–778. doi:10.1002/dmr.5610030308
   PubMedGoogle Scholar
• Furman BL. Streptozotocin‐induced diabetic models in mice and rats. Curr Protoc Pharmacol. 2015;70(1):5.47. 41–45.47. 20. doi:10.1002/0471141755.ph0547s70
   PubMedGoogle Scholar
• OECD. Organization for Economic Growth Development(OECD)guidelines for the Testing of Chemicals: Acute Oral Toxicity Up and DownProcedure (UDP); 2008.
   Google Scholar
• Zhang M, Lv X-Y, Li J, Xu Z-G, Chen L. The characterization of high-fat diet and multiple low-dose streptozotocin induced type 2 diabetes rat model. Exp Diabetes Res. 2009;2008.
   Google Scholar
• Yohannes K, Gomathi P, Aman K In vivo antidiabetic and in vitro antioxidant activity of Myrica salicifolia Hochst. ex A. Rich. (Myricaceae) root extract in streptozotocin-induced diabetic mice. Paper presented at: Diabetic Medicine; 2018.
   Google Scholar
• Vareda PMP, Saldanha LL, NAdP C, Violato NM, Dokkedal AL, Bosqueiro JR. Myrcia bella Leaf Extract Presents Hypoglycemic Activity via PI3k/Akt Insulin Signaling Pathway. Evid Based Complement Alternat Med. 2014;2014:1–11. doi:10.1155/2014/543606
   Web of Science ®Google Scholar
• Geetha G, Kalavalarasariel PG, Sankar V. Anti diabetic effect of Achyranthes rubrofusca leaf extracts on alloxan induced diabetic rats. Pak J Pharm Sci. 2011;24(2):193–199.
   PubMedGoogle Scholar
• Joseph S, Kumar L, Bai VN. Evaluation of anti-diabetic activity of Strobilanthes cuspidata in alloxan induced diabetic rats and the effect of bioactive compounds on inhibition of [alpha]-amylase enzyme. J Pharmacogn Phytochem. 2016;5(3):169.
   Google Scholar
• Vidhya R, Gandhi GR, Jothi G, Radhika J, Brindha P. Evaluation of antidiabetic potential of Achyranthes aspera Linn. on alloxan induced diabetic animals. Int J Pharm Pharm Sci. 2012;4(5):577–580.
   Google Scholar
• Kabbaoui M, Chda A, Mejrhit N, et al. Antidiabetic effect of Thymus satureioides aqueous extract in streptozotocin-induced diabetic rats. Int J Pharm Pharm Sci. 2016;8(9):140–145. doi:10.22159/ijpps.2016v8i9.12647
   Google Scholar
• Adisa RA, Choudhary MI, Olorunsogo OO. Hypoglycemic activity of Buchholzia coriacea (Capparaceae) seeds in streptozotocin-induced diabetic rats and mice. Exp Toxicol Pathol. 2011;63(7–8):619–625. doi:10.1016/j.etp.2010.05.002
   PubMedGoogle Scholar
• Hammeso WW, Emiru YK, Ayalew Getahun K, Kahaliw W. Antidiabetic and antihyperlipidemic activities of the leaf latex extract of aloe megalacantha baker (Aloaceae) in Streptozotocin-induced diabetic model. Evid Based Complement Alternat Med. 2019;2019:1–9. doi:10.1155/2019/8263786
   Web of Science ®Google Scholar
• Aboonabi A, Rahmat A, Othman F. Antioxidant effect of pomegranate against streptozotocin-nicotinamide generated oxidative stress induced diabetic rats. Toxicol Rep. 2014;1:915–922. doi:10.1016/j.toxrep.2014.10.022
   PubMedGoogle Scholar
• Lukic ML, Stošic-Grujicic S, Shahin A. Effector mechanisms in low-dose streptozotocin-induced diabetes. J Immunol Res. 1998;6(1–2):119–128.
   Google Scholar
• Parmar GR, Pundarikakshudu K, Balaraman R. Antidiabetic and antihyperlipidemic activity of Euphorbia thymifolia L. extracts on streptozotocin-nicotinamide induced type 2 diabetic rats. J Appl Pharm Sci. 2017;7(08):078–084.
   Google Scholar
• Gebreyohannis T, Shibeshi W, Asres K. Effects of Solvent Fractions of Caylusea abyssinica (Fresen.) Fisch. and Mey. on Blood Glucose Levels of Normoglycemic, Glucose Loaded and Streptozotocin-Induced Diabetic Rodents. J Nat Remedies. 2013;14(1):67–75.
   Google Scholar
• Tanko Y, Jimoh AG, Mohammed A, Musa K. Hypoglycaemic effects of the methanolic extract of aerial part of Chrysanthellum indicum in rats. J Nat Prod Plant Res. 2011;1:1–7.
   Google Scholar
• Nagmoti DM, Kothavade PS, Bulani VD, Gawali NB, Juvekar AR. Antidiabetic and antihyperlipidemic activity of Pithecellobium dulce (Roxb.) Benth seeds extract in streptozotocin-induced diabetic rats. Eur J Integr Med. 2015;7(3):263–273. doi:10.1016/j.eujim.2015.01.001
   Google Scholar
• Tekulu GH, Araya EM, Mengesha HG. In vitro α-amylase inhibitory effect of TLC isolates of Aloe megalacantha baker and Aloe monticola Reynolds. BMC Complement Altern Med. 2019;19(1):206. doi:10.1186/s12906-019-2622-5
   PubMedGoogle Scholar
• Aloulou A, Hamden K, Elloumi D, et al. Hypoglycemic and antilipidemic properties of kombucha tea in alloxan-induced diabetic rats. BMC Complement Altern Med. 2012;12(1):63. doi:10.1186/1472-6882-12-63
   PubMed Web of Science ®Google Scholar
• Jadhav R, Puchchakayala G. Hypoglycemic and antidiabetic activity of flavonoids: boswellic acid, ellagic acid, quercetin, rutin on streptozotocin-nicotinamide induced type 2 diabetic rats. Group. 2012;1:100g.
   Google Scholar
• Dinku T, Tadesse S, Asres K. Antidiabetic activity of the leaf extracts of Pentas schimperiana subsp. schimperiana (A. Rich) Vatke on alloxan-induced diabetic mice. Ethiop Pharm J. 2010;28:22–26.
   Google Scholar
• Ramkumar KM, Vanitha P, Uma C, Suganya N, Bhakkiyalakshmi E, Sujatha J. Antidiabetic activity of alcoholic stem extract of Gymnema montanum in streptozotocin-induced diabetic rats. Food Chem Toxicol. 2011;49(12):3390–3394. doi:10.1016/j.fct.2011.09.027
   PubMed Web of Science ®Google Scholar
• Prakash O, Kumar R, Srivastava R, Tripathi P, Ajeet MS. Plants explored with Anti-diabetic properties: a review. Am J Pharmacol Sci. 2015;3(3):55–66.
   Google Scholar
• Dessalegn E, Bultosa G, Haki GD, Rupasinghe HV. Antioxidant and-amylase inhibition activities in vitro of various solvent extracts of Thymus schimperi Ronniger. J Med Plant Res. 2015;9(15):515–524. doi:10.5897/JMPR2014.5431
   Google Scholar