Associations Between Gestational Diabetes Mellitus Risk and Folate Status in Early Pregnancy and MTHFR C677T Polymorphisms in Chinese Women

References

• Zhu Y, Zhang C. Prevalence of gestational diabetes and risk of progression to type 2 diabetes: a global perspective. Curr Diab Rep. 2016;16(1):7. doi:10.1007/s11892-015-0699-x
   PubMed Web of Science ®Google Scholar
• Zhu WW, Yang HX, Wei YM, et al. Evaluation of the value of fasting plasma glucose in the first prenatal visit to diagnose gestational diabetes mellitus in china. Diabetes Care. 2013;36:586–590. doi:10.2337/dc12-1157
   PubMed Web of Science ®Google Scholar
• Guariguata L, Linnenkamp U, Beagley J, Whiting DR, Cho NH. Global estimates of the prevalence of hyperglycaemia in pregnancy. Diabetes Res Clin Pract. 2014;103(2):176e85. doi:10.1016/j.diabres.2013.11.003
   Google Scholar
• Mishra S, Rao CR, Shetty A. Trends in the diagnosis of gestational diabetes mellitus. Scientifica (Cairo). 2016;2016:5489015.
   PubMedGoogle Scholar
• Hod M, Kapur A, Sacks DA, et al. The International Federation of Gynecology and Obstetrics (FIGO) Initiative on gestational diabetes mellitus: a pragmatic guide for diagnosis, management, and care. Int J Gynaecol Obstet. 2015;131(Suppl 3):S173–S211.
   PubMed Web of Science ®Google Scholar
• Farrar D, Simmonds M, Bryant M, et al. Hyperglycaemia and risk of adverse perinatal outcomes: systematic review and meta-analysis. BMJ. 2016;354:i4694. doi:10.1136/bmj.i4694
   PubMed Web of Science ®Google Scholar
• Lowe WL Jr, Scholtens DM, Kuang A, et al. Hyperglycemia and adverse pregnancy outcome follow-up study (HAPO FUS): maternal gestational diabetes mellitus and childhood glucose metabolism. Diabetes Care. 2019;42(3):372–380. doi:10.2337/dc18-1646
   PubMed Web of Science ®Google Scholar
• Di Cianni G, Lacaria E, Lencioni C, Resi V. Preventing type 2 diabetes and cardiovascular disease in women with gestational diabetes – the evidence and potential strategies. Diabetes Res Clin Pract. 2018;145:184–192. doi:10.1016/j.diabres.2018.04.021
   PubMedGoogle Scholar
• Page KA, Buchanan TA. The vicious cycle of maternal diabetes and obesity: moving from “what” to “how” and “why.”. J Pediatr. 2011;158:872–873. doi:10.1016/j.jpeds.2011.02.003
   PubMedGoogle Scholar
• Bibbins-Domingo K, Grossman DC, Curry SJ, et al. Folic acid supplementation for the prevention of neural tube defects: US preventive services task force recommendation statement. JAMA. 2017;317:183–189. doi:10.1001/jama.2016.19438
   PubMed Web of Science ®Google Scholar
• Yajnik CS, Deshpande SS, Jackson AA, et al. Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study. Diabetologia. 2008;51:29–38. doi:10.1007/s00125-007-0793-y
   PubMed Web of Science ®Google Scholar
• Huang Y, He Y, Sun X, He Y, Li Y, Sun C. Maternal high folic acid supplement promotes glucose intolerance and insulin resistance in male mouse offspring fed a high-fat diet. Int J Mol Sci. 2014;15:6298–6313. doi:10.3390/ijms15046298
   PubMedGoogle Scholar
• Zhu B, Ge X, Huang K, et al. Folic acid supplement intake in early pregnancy increases risk of gestational diabetes mellitus: evidence from a prospective cohort study. Diabetes Care. 2016;39:e36–7. doi:10.2337/dc15-2389
   PubMed Web of Science ®Google Scholar
• Lai JS, Pang WW, Cai S, et al. High folate and low vitamin B12 status during pregnancy is associated with gestational diabetes mellitus. Clin Nutr. 2018;37:940–947. doi:10.1016/j.clnu.2017.03.022
   PubMed Web of Science ®Google Scholar
• Li Q, Zhang Y, Huang L, et al. High-dose folic acid supplement use from prepregnancy through midpregnancy is associated with increased risk of gestational diabetes mellitus: a prospective cohort study. Diabetes Care. 2019;42:e113–e115. doi:10.2337/dc18-2572
   PubMed Web of Science ®Google Scholar
• Cordero AM, Crider KS, Rogers LM, Cannon MJ, Berry RJ. Optimal serum and red blood cell folate concentrations in women of reproductive age for prevention of neural tube defects: World Health Organization guidelines. MMWR Morb Mortal Wkly Rep. 2015;64:421–423.
   PubMed Web of Science ®Google Scholar
• Botto LD, Yang Q. 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. Am J Epidemiol. 2000;151(9):862–877. doi:10.1093/oxfordjournals.aje.a010290
   PubMed Web of Science ®Google Scholar
• Pfeiffer CM, Fazili Z. Folate analytical methodology. In: Baily LB, editor. Folate in Health and Diseases. 2nd ed. Boca Raton: CRC Press; 2010:517–574.
   Google Scholar
• Xie K, Xu P, Fu Z, et al. Association of maternal folate status in the second trimester of pregnancy with the risk of gestational diabetes mellitus. Food Sci Nutr. 2019;7:3759–3765. doi:10.1002/fsn3.1235
   PubMed Web of Science ®Google Scholar
• Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412–419. doi:10.1007/BF00280883
   PubMed Web of Science ®Google Scholar
• Selhub J, Morris MS, Jacques PF. In vitamin B12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations. Proc Natl Acad Sci U S A. 2007;104:19995–20000. doi:10.1073/pnas.0709487104
   PubMed Web of Science ®Google Scholar
• Idzior-Walus B, Cyganek K, Sztefko K, et al. Total plasma homocysteine correlates in women with gestational diabetes. Arch Gynecol Obstet. 2008;278:309e13. doi:10.1007/s00404-008-0571-1
   Google Scholar
• Krishnaveni GV, Hill JC, Veena SR, et al. Low plasma vitamin B12 in pregnancy is associated with gestational ‘diabesity’ and later diabetes. Diabetologia. 2009;52:2350–2358. doi:10.1007/s00125-009-1499-0
   PubMed Web of Science ®Google Scholar
• Sukumar N, Venkataraman H, Wilson S, et al. Vitamin B12 status among pregnant women in the UK and Its Association with Obesity and Gestational Diabetes. Nutrients. 2016;8:pii: E768. doi:10.3390/nu8120768
   PubMedGoogle Scholar
• Wang S, Ge X, Zhu B, et al. Maternal continuing folic acid supplementation after the first trimester of pregnancy increased the risk of large-for-gestational-age birth: a population-based birth cohort study. Nutrients. 2016;8(8):pii: E493. doi:10.3390/nu8080493
   Google Scholar
• Troen AM, Mitchell B, Sorensen B, et al. Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenopausal women. J Nutr. 2006;136(1):189–194. doi:10.1093/jn/136.1.189
   PubMed Web of Science ®Google Scholar
• Zhao YH, Wang DP, Zhang LL, Zhang F, Wang DM, Zhang WY. Genomic expression profiles of blood and placenta reveal significant immune-related pathways and categories in Chinese women with gestational diabetes mellitus. Diabet Med. 2011;28:237–246. doi:10.1111/j.1464-5491.2010.03140.x
   PubMed Web of Science ®Google Scholar
• Rai V. Folate pathway gene MTHFR C677T polymorphism and risk of lung cancer in Asian populations. Asian Pac J Cancer Prev. 2014;15(21):9259–9264. doi:10.7314/APJCP.2014.15.21.9259
   PubMedGoogle Scholar
• Liu NB, Li J, Qi JF, Zhang ZZ, Wu X, Zhang JH. Methylenetetrahydrofolate reductase 677TT genotype may be associated with an increased lung cancer risk in North China: an updated meta-analysis. Med Sci Monit. 2014;20:2817–2823. doi:10.12659/MSM.892050
   PubMedGoogle Scholar
• Crider KS, Zhu JH, Hao L, et al. MTHFR 677C→T genotype is associated with folate and homocysteine concentrations in a large, population-based, double-blind trial of folic acid supplementation. Am J Clin Nutr. 2011;93:1365–1372. doi:10.3945/ajcn.110.004671
   PubMed Web of Science ®Google Scholar
• Weiss N, Heydrick SJ, Postea O, Keller C, Jr JF K, Loscalzo J. Influence of hyperhomocysteinemia on the cellular redox state-impact on homocysteine-induced endothelial dysfunction. Clin Chem Lab Med. 2003;41:1455e61. doi:10.1515/CCLM.2003.223
   Google Scholar
• Meigs JB, Jacques PF, Selhub J, et al. Fasting plasma homocysteine levels in the insulin resistance syndrome: the Framingham offspring study. Diabetes Care. 2001;24(8):1403e10. doi:10.2337/diacare.24.8.1403
   Google Scholar
• Ni J, Zhang L, Zhou T, et al. Association between the MTHFR C677T polymorphism, blood folate and vitamin B12 deficiency, and elevated serum total homocysteine in healthy individuals in Yunnan Province, China. J Chin Med Assoc. 2017;80:147–153. doi:10.1016/j.jcma.2016.07.005
   PubMed Web of Science ®Google Scholar
• Khan IA, Shaik NA, Kamineni V, Jahan P, Hasan Q, Rao P. Evaluation of gestational diabetes mellitus risk in South Indian women based on MTHFR (C677T) and FVL (G1691A) mutations. Front Pediatr. 2015;3:34. doi:10.3389/fped.2015.00034
   PubMedGoogle Scholar