99
Views
9
CrossRef citations to date
0
Altmetric
Original Research

Increase in Tryptase and Its Role in the Synovial Membrane of Overweight and Obese Patients with Osteoarthritis of the Knee

, , , , ORCID Icon, , , , & show all
Pages 1491-1497 | Published online: 05 May 2020

References

  • Coggon D, Reading I, Croft P, McLaren M, Barrett D, Cooper C. Knee osteoarthritis and obesity. Int J Obes Relat Metab Disord. 2001;25:622–627.
  • Felson DT. Relation of obesity and of vocational and avocational risk factors to osteoarthritis. J Rheumatol. 2005;32:1133–1135.
  • Hart DJ, Spector TD. The relationship of obesity, fat distribution and osteoarthritis in women in the general population: the Chingford Study. J Rheumatol. 1993;20:331–335.
  • Lachance L, Sowers M, Jamadar D, Jannausch M, Hochberg M, Crutchfield M. The experience of pain and emergent osteoarthritis of the knee. Osteoarthr Cartilage. 2001;9:527–532. doi:10.1053/joca.2000.0429
  • Runhaar J, Koes BW, Clockaerts S, Bierma-Zeinstra SM. A systematic review on changed biomechanics of lower extremities in obese individuals: a possible role in development of osteoarthritis. Obes Rev. 2011;12:1071–1082. doi:10.1111/j.1467-789X.2011.00916.x
  • Grotle M, Hagen KB, Natvig B, Dahl FA, Kvien TK. Obesity and osteoarthritis in knee, hip and/or hand: an epidemiological study in the general population with 10 years follow-up. BMC Musculoskelet Disord. 2008;9:132. doi:10.1186/1471-2474-9-132
  • Oliveria SA, Felson DT, Cirillo PA, Reed JI, Walker AM. Body weight, body mass index, and incident symptomatic osteoarthritis of the hand, hip, and knee. Epidemiology. 1999;10:161–166. doi:10.1097/00001648-199903000-00013
  • Nigrovic PA, Lee DM. Synovial mast cells: role in acute and chronic arthritis. Immunol Rev. 2007;217:19–37. doi:10.1111/j.1600-065X.2007.00506.x
  • Ramirez J, Celis R, Usategui A, et al. Immunopathologic characterization of ultrasound-defined synovitis in rheumatoid arthritis patients in clinical remission. Arthritis Res Ther. 2016;18:74. doi:10.1186/s13075-016-0970-9
  • Rivellese F, Mauro D, Nerviani A, et al. Mast cells in early rheumatoid arthritis associate with disease severity and support B cell autoantibody production. Ann Rheum Dis. 2018;77(12):1773–1781. doi:10.1136/annrheumdis-2018-213418
  • Rivellese F, Rossi FW, Galdiero MR, Pitzalis C, de Paulis A. Mast cells in early rheumatoid arthritis. Int J Mol Sci. 2019;20(8):2040. doi:10.3390/ijms20082040
  • Buckley MG, Gallagher PJ, Walls AF. Mast cell subpopulations in the synovial tissue of patients with osteoarthritis: selective increase in numbers of tryptase-positive, chymase-negative mast cells. J Pathol. 1998;186:67–74. doi:10.1002/(SICI)1096-9896(199809)186:1<67::AID-PATH132>3.0.CO;2-D
  • de Lange-brokaar BJ, Kloppenburg M, Andersen SN, et al. Characterization of synovial mast cells in knee osteoarthritis: association with clinical parameters. Osteoarthr Cartilage. 2016;24:664–671. doi:10.1016/j.joca.2015.11.011
  • Dean G, Hoyland JA, Denton J, Donn RP, Freemont AJ. Mast cells in the synovium and synovial fluid in osteoarthritis. Br J Rheumatol. 1993;32:671–675. doi:10.1093/rheumatology/32.8.671
  • Noordenbos T, Yeremenko N, Gofita I, et al. Interleukin-17-positive mast cells contribute to synovial inflammation in spondylarthritis. Arthritis Rheum. 2012;64:99–109. doi:10.1002/art.33396
  • Uchida K, Takano S, Inoue G, et al. Increase in mast cell marker expression in the synovium of obese patients with osteoarthritis of the knee. Diabetes Metab Syndr Obes. 2019;12:377–382. doi:10.2147/DMSO.S201523
  • Caughey GH. Mast cell tryptases and chymases in inflammation and host defense. Immunol Rev. 2007;217:141–154. doi:10.1111/j.1600-065X.2007.00509.x
  • Nakano S, Mishiro T, Takahara S, et al. Distinct expression of mast cell tryptase and protease activated receptor-2 in synovia of rheumatoid arthritis and osteoarthritis. Clin Rheumatol. 2007;26:1284–1292. doi:10.1007/s10067-006-0495-8
  • Compton SJ, Cairns JA, Holgate ST, Walls AF. The role of mast cell tryptase in regulating endothelial cell proliferation, cytokine release, and adhesion molecule expression: tryptase induces expression of mRNA for IL-1 beta and IL-8 and stimulates the selective release of IL-8 from human umbilical vein endothelial cells. J Immunol. 1998;161:1939–1946.
  • Mullan CS, Riley M, Clarke D, et al. β-Tryptase regulates IL-8 expression in airway smooth muscle cells by a PAR-2–independent mechanism. Am J Respir Cell Mol Biol. 2008;38(5):600–608. doi:10.1165/rcmb.2007-0082OC
  • Borden P, Solymar D, Sucharczuk A, Lindman B, Cannon P, Heller RA. Cytokine control of interstitial collagenase and collagenase-3 gene expression in human chondrocytes. J Biol Chem. 1996;271:23577–23581. doi:10.1074/jbc.271.38.23577
  • Lee YA, Choi HM, Lee SH, et al. Hypoxia differentially affects IL-1beta-stimulated MMP-1 and MMP-13 expression of fibroblast-like synoviocytes in an HIF-1alpha-dependent manner. Rheumatology (Oxford). 2012;51:443–450. doi:10.1093/rheumatology/ker327
  • Takano S, Uchida K, Miyagi M, et al. Nerve growth factor regulation by TNF-alpha and IL-1beta in synovial macrophages and fibroblasts in osteoarthritic mice. J Immunol Res. 2016;2016:5706359. doi:10.1155/2016/5706359
  • Takano S, Uchida K, Inoue G, et al. Nerve growth factor regulation and production by macrophages in osteoarthritic synovium. Clin Exp Immunol. 2017;190:235–243. doi:10.1111/cei.13007
  • Takano S, Uchida K, Miyagi M, et al. Adrenomedullin regulates IL-1beta gene expression in F4/80+ macrophages during synovial inflammation. J Immunol Res. 2017;2017:9832430. doi:10.1155/2017/9832430
  • Denoble AE, Huffman KM, Stabler TV, et al. Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation. Proc Natl Acad Sci U S A. 2011;108:2088–2093. doi:10.1073/pnas.1012743108
  • Harms S, Larson R, Sahmoun AE, Beal JR. Obesity increases the likelihood of total joint replacement surgery among younger adults. Int Orthop. 2007;31:23–26. doi:10.1007/s00264-006-0130-y
  • Manek N, Hart D, Spector T. The association of body mass index and osteoarthritis of the knee joint. Arthritis Rheum. 2003;48:1024–1029. doi:10.1002/art.10884
  • Divoux A, Moutel S, Poitou C, et al. Mast cells in human adipose tissue: link with morbid obesity, inflammatory status, and diabetes. J Clin Endocrinol Metab. 2012;97:E1677–E1685. doi:10.1210/jc.2012-1532
  • Fenger RV, Linneberg A, Vidal C, et al. Determinants of serum tryptase in a general population: the relationship of serum tryptase to obesity and asthma. Int Arch Allergy Immunol. 2012;157:151–158. doi:10.1159/000327535
  • Moreno M, Puig J, Serrano M, et al. Circulating tryptase as a marker for subclinical atherosclerosis in obese subjects. PLoS One. 2014;9:e97014. doi:10.1371/journal.pone.0097014
  • Russi AE, Walker-Caulfield ME, Brown MA. Mast cell inflammasome activity in the meninges regulates EAE disease severity. Clin Immunol. 2018;189:14–22. doi:10.1016/j.clim.2016.04.009
  • Bhattacharyya SP, Drucker I, Reshef T, Kirshenbaum AS, Metcalfe DD, Mekori YA. Activated T lymphocytes induce degranulation and cytokine production by human mast cells following cell-to-cell contact. J Leukoc Biol. 1998;63:337–341. doi:10.1002/jlb.63.3.337
  • de Souza Junior DA, Mazucato VM, Santana AC, Oliver C, Jamur MC. Mast cells interact with endothelial cells to accelerate in vitro angiogenesis. Int J Mol Sci. 2017;18:2674.
  • Fitzgerald SM, Lee SA, Hall HK, Chi DS, Krishnaswamy G. Human lung fibroblasts express interleukin-6 in response to signaling after mast cell contact. Am J Respir Cell Mol Biol. 2004;30:585–593. doi:10.1165/rcmb.2003-0282OC
  • Sandler C, Lindstedt KA, Joutsiniemi S, et al. Selective activation of mast cells in rheumatoid synovial tissue results in production of TNF-alpha, IL-1beta and IL-1Ra. Inflamm Res. 2007;56:230–239. doi:10.1007/s00011-007-6135-1
  • Xu JM, Shi GP. Emerging role of mast cells and macrophages in cardiovascular and metabolic diseases. Endocr Rev. 2012;33:71–108. doi:10.1210/er.2011-0013