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Original Research

Serum Human Epididymis Protein 4 Level is Associated with Cognitive Function in Patients with Diabetes Mellitus

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Pages 3919-3924 | Published online: 22 Oct 2020

References

  • Kukull WA, Higdon R, Bowen JD, et al. Dementia and Alzheimer disease incidence: a prospective cohort study. Arch Neurol. 2002;59:1737–1746. doi:10.1001/archneur.59.11.1737
  • Akomolafe A, Beiser A, Meigs JB, et al. Diabetes mellitus and risk of developing Alzheimer disease: results from the Framingham Study. Arch Neurol. 2006;63(11):1551–1555. doi:10.1001/archneur.63.11.1551
  • Wrighten SA, Piroli GG, Grillo CA, et al. A look inside the diabetic brain: contributors to diabetes-induced brain aging. Biochim Biophys Acta. 2009;1792:444–453.
  • Ott A, Stolk RP, van Harskamp F, et al. Diabetes mellitus and the risk of dementia: the Rotterdam Study. Neurology. 1999;53:1937–1942. doi:10.1212/WNL.53.9.1937
  • Biessels GJ, Staekenborg S, Brunner E, et al. Risk of dementia in diabetes mellitus: a systematic review. Lancet Neurol. 2006;5:64–74. doi:10.1016/S1474-4422(05)70284-2
  • Ghezzi P, Floridi L, Boraschi D, et al. Oxidative Stress and Inflammation Induced by Environmental and Psychological Stressors: A Biomarker Perspective. Antioxid Redox Signal. 2018;28(9):852–872.
  • Kirchhoff C, Habben I, Ivell R, et al. A major human epididymis-specific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors. Biol Reprod. 1991;45(2):350–357. doi:10.1095/biolreprod45.2.350
  • Kirchhoff C. Molecular characterization of epididymal proteins. Rev Reprod. 1998;3(2):86–95.
  • Hellstrom I, Raycraft J, Hayden-Ledbetter M, et al. The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma. Cancer Res. 2003;63(13):3695–3700.
  • Plebani M. HE4 in gynecological cancers: report of a European investigators and experts meeting. Clin Chem Lab Med. 2012;50(12):2127–2136. doi:10.1515/cclm-2012-0373
  • Hertlein L, Stieber P, Kirschenhofer A, et al. Human epididymis protein 4 (HE4) in benign and malignant diseases. Clin Chem Lab Med. 2012;50(12):2181–2188. doi:10.1515/cclm-2012-0097
  • Galgano MT, Hampton GM, Frierson HJ. Comprehensive analysis of HE4 expression in normal and malignant human tissues. Mod Pathol. 2006;19(6):847–853.
  • Bingle CD, Vyakarnam A. Novel innate immune functions of the whey acidic protein family. Trends Immunol. 2008;29(9):444–453. doi:10.1016/j.it.2008.07.001
  • Escudero JM, Auge JM, Filella X, et al. Comparison of serum human epididymis protein 4 with cancer antigen 125 as a tumor marker in patients with malignant and nonmalignant diseases. Clin Chem. 2011;57(11):1534–1544. doi:10.1373/clinchem.2010.157073
  • Drapkin R, von Horsten HH, Lin Y, et al. Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas. Cancer Res. 2005;65(6):2162–2169. doi:10.1158/0008-5472.CAN-04-3924
  • Yaffe K, Kanaya A, Lindquist K, et al. The metabolic syndrome, inflammation, and risk of cognitive decline. JAMA. 2004;292(18):2237. doi:10.1001/jama.292.18.2237
  • Schram MT, Euser SM, Craen AJD, et al. Systemic markers of inflammation and cognitive decline in old age. Alzheimers Dement. 2006;2(3–supp–S):S154. doi:10.1016/j.jalz.2006.05.575
  • Bucht G, Adolfsson R, Lithner F, et al. Changes in blood glucose and insulin secretion in patients with senile dementia of alzheimer type. Acta Med Scand. 2010;213(5):387–392. doi:10.1111/j.0954-6820.1983.tb03756.x
  • Sundar U, Sharma A, Yeolekar ME. Presenile dementia–etiology, clinical profile and treatment response at four month follow up. J Assoc Physicians India. 2004;52:953–958.
  • Alberti KG, Zimmet PZ. New diagnostic criteria and classification of diabetes–again? Diabet Med. 2015;15(7):535–536. doi:10.1002/(SICI)1096-9136(199807)15:7<535::AID-DIA670>3.0.CO;2-Q
  • Levey AS, Stevens LA, Schmid CH, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150(9):604–612. doi:10.7326/0003-4819-150-9-200905050-00006
  • Chen Q, Mo R, Wu N, et al. Berberine ameliorates diabetes-associated cognitive decline through modulation of aberrant inflammation response and insulin signaling pathway in DM rats. Front Pharmacol. 2017;8:334. doi:10.3389/fphar.2017.00334
  • Tian X, Liu Y, Ren G, et al. Resveratrol limits diabetes-associated cognitive decline in rats by preventing oxidative stress and inflammation and modulating hippocampal structural synaptic plasticity. Brain Res. 2016;1650:1–9.
  • Liu YW, Zhu X, Yang QQ, et al. Suppression of methylglyoxal hyperactivity by mangiferin can prevent diabetes-associated cognitive decline in rats. Psychopharmacology. 2013;228(4):585–594. doi:10.1007/s00213-013-3061-5
  • De Boer RA, Cao Q, Postmus D, et al. The WAP four-disulfide core domain protein HE4: a novel biomarker for heart failure. JACC Heart Fail. 2013;1(2):164–169. doi:10.1016/j.jchf.2012.11.005
  • Piek A, Meijers WC, Schroten NF, Gansevoort RT, de Boer RA, Silljé HH. HE4 serum levels are associated with heart failure severity in patients with chronic heart failure. J Card Fail. 2017;23(1):12–19. doi:10.1016/j.cardfail.2016.05.002
  • Yuan T, Li Y. Human epididymis protein 4 as a potential biomarker of chronic kidney disease in female patients with normal ovarian function. Lab Med. 2017;48(3):238–243. doi:10.1093/labmed/lmx036
  • Huang Y, Jiang H, Zhu L. Human epididymis protein 4 as an indicator of acute heart failure in patients with chronic kidney disease. Lab Med. 2020;51(2):169–175.
  • Nagy B Jr, Krasznai ZT, Balla H, et al. Elevated human epididymis protein 4 concentrations in chronic kidney disease. Ann Clin Biochem. 2012;49(Pt4):377–380. doi:10.1258/acb.2011.011258