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Original Research

p53 Mediates GnRH Secretion via Lin28/let-7 System in GT1-7 Cells

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Pages 4681-4688 | Published online: 01 Dec 2020

References

  • Gajdos ZKZ, Hirschhorn JN, Palmert MR. What controls the timing of puberty? An update on progress from genetic investigation. Curr Opin Endocrinol Diabetes Obes. 2009;16(1):16–24. doi:10.1097/MED.0b013e328320253c
  • Macedo DB, Brito VN, Latronico AC. New causes of central precocious puberty: the role of genetic factors. Neuroendocrinology. 2014;100(1):1–8. doi:10.1159/000366282
  • Kaplowitz PB. Link between body fat and the timing of puberty. Pediatrics. 2008;121(Supplement 3):S208–S217. doi:10.1542/peds.2007-1813F
  • Aksglaede L, Juul A, Olsen LW, et al. Age at puberty and the emerging obesity epidemic. PLoS One. 2014;63(12):e8450. doi:10.1371/journal.pone.0008450
  • Brill DS, Moenter SM. Androgen receptor antagonism and an insulin sensitizer block the advancement of vaginal opening by high-fat diet in mice. Biol Reprod. 2009;81(6):1093–1098. doi:10.1095/biolreprod.109.079301
  • Feng Li X, Lin YS, Kinsey-Jones JS, et al. High-fat diet increases LH pulse frequency and kisspeptin-neurokinin B expression in puberty-advanced female rats. Endocrinology. 2012;153(9):4422–4431. doi:10.1210/en.2012-1223
  • Ullah R, Su Y, Shen Y, et al. Postnatal feeding with high-fat diet induces obesity and precocious puberty in C57BL/6J mouse pups: a novel model of obesity and puberty. Front Med. 2012;153(2):4422–4431. doi:10.1007/s11684-017-0530-y
  • Chen T, Chen C, Wu H, et al. Overexpression of p53 accelerates puberty in high-fat diet–fed mice through Lin28/let-7 system. Exp Biol Med. 2020:1535370220961320. doi10.1177/1535370220961320
  • Ojeda SR, Dubay C, Lomniczi A, et al. Gene networks and the neuroendocrine regulation of puberty. Mol Cell Endocrinol. 2010;324(1–2):3–11. doi:10.1016/J.MCE.2009.12.003
  • Kauffman AS, Clifton DK, Steiner RA. Emerging ideas about kisspeptin–GPR54 signaling in the neuroendocrine regulation of reproduction. Trends Neurosci. 2007;30(10):504–511. doi:10.1016/j.tins.2007.08.001
  • Terasawa EI, Fernandez DL. Neurobiological mechanisms of the onset of puberty in primates. Endocr Rev. 2001;22:111–151.
  • Roth CL, Mastronardi C, Lomniczi A, et al. Expression of a tumor-related gene network increases in the mammalian hypothalamus at the time of female puberty. Endocrinology. 2007;148(11):5147–5161. doi:10.1210/en.2007-0634
  • Meyre D, Delplanque J, Chèvre J-C, et al. Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat Genet. 2009;41(2):157. doi:10.1038/ng.301
  • Lu Y, Ma Z, Zhang Z, et al. Yin Yang 1 promotes hepatic steatosis through repression of farnesoid X receptor in obese mice. Gut. 2014;63(1):170LP– 178. doi:10.1136/gutjnl-2012-303150
  • Kung C-P, Leu -J-J, Basu S, et al. The P72R polymorphism of p53 predisposes to obesity and metabolic dysfunction. Cell Rep. 2016;14(10):2413–2425. doi:10.1016/J.CELREP.2016.02.037
  • Molchadsky A, Ezra O, Amendola PG, et al. p53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity. Cell Death Differ. 2013;20(5):774–783. doi:10.1038/cdd.2013.9
  • Roa J, Tena-Sempere M. Energy balance and puberty onset: emerging role of central mTOR signaling. Trends Endocrinol Metab. 2010;21(9):519–528. doi:10.1016/j.tem.2010.05.003
  • Oakley AE, Clifton DK, Steiner RA. Kisspeptin signaling in the brain. Endocr Rev. 2009;30:713–743.
  • Castellano JM, Roa J, Luque RM, et al. KiSS-1/kisspeptins and the metabolic control of reproduction: physiologic roles and putative physiopathological implications. Peptides. 2009;30(1):139–145. doi:10.1016/j.peptides.2008.06.007
  • Quennell JH, Mulligan AC, Tups A, et al. Leptin indirectly regulates gonadotropin-releasing hormone neuronal function. Endocrinology. 2009;150(6):2805–2812. doi:10.1210/en.2008-1693
  • Kalamatianos T, Grimshaw SE, Poorun R, et al. Fasting reduces KiSS-1 expression in the anteroventral periventricular nucleus (AVPV): effects of fasting on the expression of KiSS-1 and neuropeptide Y in the AVPV or arcuate nucleus of female rats. J Neuroendocrinol. 2008;20(9):1089–1097. doi:10.1111/j.1365-2826.2008.01757.x
  • Roa J, Garcia-Galiano D, Varela L, et al. The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system. Endocrinology. 2009;150(11):5016–5026. doi:10.1210/en.2009-0096
  • Vazquez MJ, Toro CA, Castellano JM, et al. SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression. Nat Commun. 2018;9(1):4194. doi:10.1038/s41467-018-06459-9
  • Serria MS, Ikeda H, Omoteyama K, et al. Regulation and differential expression of the c-MAF gene in differentiating cultured cells. Biochem Biophys Res Commun. 2003;310(2):318–326. doi:10.1016/j.bbrc.2003.08.144
  • Tsuchiya M, Taniguchi S, Yasuda K, et al. Potential roles of large mafs in cell lineages and developing pancreas. Pancreas. 2006;32(4):408–416. doi:10.1097/01.mpa.0000220867.64787.99
  • Agnello D, Lankford CSR, Bream J, et al. Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. J Clin Immunol. 2003;23:147–161. doi:10.1023/A:1023381027062
  • Lai C-Y, Lin C-Y, Hsu -C-C, et al. Liver-directed microRNA-7a depletion induces nonalcoholic fatty liver disease by stabilizing YY1-mediated lipogenic pathways in zebrafish. Biochim Biophys Acta. 2018;1863:844–856.
  • Yokoyama M, Okada S, Nakagomi A, et al. Inhibition of endothelial p53 improves metabolic abnormalities related to dietary obesity. Cell Rep. 2014;7(5):1691–1703. doi:10.1016/j.celrep.2014.04.046
  • Kung C-P, Murphy ME. The role of the p53 tumor suppressor in metabolism and diabetes. J Endocrinol. 2016;231(2):R61–R75. doi:10.1530/JOE-16-0324
  • Zwezdaryk K, Sullivan D, Saifudeen Z. The p53/adipose-tissue/cancer nexus. Front Endocrinol (Lausanne). 2018;9:457. doi:10.3389/fendo.2018.00457
  • Zahid H, Subbaramaiah K, Iyengar NM, et al. Leptin regulation of the p53-HIF1α/PKM2-aromatase axis in breast adipose stromal cells: a novel mechanism for the obesity–breast cancer link. Int J Obes. 2018;42(4):711–720. doi:10.1038/ijo.2017.273
  • Liu X, Wang D, Zhao Y, et al. Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1). Proc Natl Acad Sci. 2011;108:1925–1930.
  • Gonfloni S, Iannizzotto V, Maiani E, et al. P53 and Sirt1: routes of metabolism and genome stability. Biochem Pharmacol. 2014;92(1):149–156. doi:10.1016/j.bcp.2014.08.034
  • Feng Z, Levine AJ. The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein. Trends Cell Biol. 2010;20(7):427–434. doi:10.1016/j.tcb.2010.03.004
  • Pasquinelli AE, Reinhart BJ, Slack F, et al. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature. 2000;408(6808):86–89. doi:10.1038/35040556
  • Viswanathan SR, Daley GQ, Gregory RI. Selective blockade of microRNA processing by Lin28. Science (80-). 2008;320(5872):97–100. doi:10.1126/science.1154040
  • Thornton JE, Gregory RI. How does Lin28 let-7 control development and disease? Trends Cell Biol. 2012;22(9):474–482. doi:10.1016/j.tcb.2012.06.001
  • Viswanathan SR, Daley GQ. Lin28: a MicroRNA regulator with a macro role. Cell. 2010;140(4):445–449. doi:10.1016/j.cell.2010.02.007
  • Chang T-C, Zeitels LR, Hwang H-W, et al. Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc Natl Acad Sci. 2007;148(9):5147–5161. doi:10.1073/pnas.0808300106
  • Sangiao-Alvarellos S, Manfredi-Lozano M, Ruiz-Pino F, et al. Changes in hypothalamic expression of the Lin28/let-7 system and related microRNAs during postnatal maturation and after experimental manipulations of puberty. Endocrinology. 2013;154(2):942–955. doi:10.1210/en.2012-2006
  • Ong KK, Elks CE, Li S, et al. Genetic variation in LIN28B is associated with the timing of puberty. Nat Genet. 2009;41(6):729. doi:10.1038/ng.382
  • Perry JRB, Stolk L, Franceschini N, et al. Meta-analysis of genome-wide association data identifies two loci influencing age at menarche. Nat Genet. 2009;41(6):648. doi:10.1038/ng.386
  • Zhu H, Shah S, Shyh-Chang N, et al. Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies. Nat Genet. 2010;42(7):626. doi:10.1038/ng.593
  • Zhu H, Ng SC, Segr AV, et al. The Lin28/let-7 axis regulates glucose metabolism. Cell. 2011;147:81–94.
  • Kim JD, Toda C, Ramírez CM, et al. Hypothalamic ventromedial Lin28a enhances glucose metabolism in diet-induced obesity. Diabetes. 2017;66(8):2102–2111. doi:10.2337/db16-1558