Association of Insulin Glargine Treatment with Bone Mineral Density in Patients with Type 2 Diabetes Mellitus

References

• Avdicova M , Aris T , Sakarya S . Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants. Lancet . 2016;387(10027):1513–1530. doi:10.1016/S0140-6736(16)00618-8 27061677
   PubMed Web of Science ®Google Scholar
• Hsu JY , Cheng CY , Hsu CY . Type 2 diabetes mellitus severity correlates with risk of hip fracture in patients with osteoporosis. Neth J Med . 2018;76(2):65–71.29515003
   PubMed Web of Science ®Google Scholar
• Zhang P , Zhang X , Brown J , et al. Global healthcare expenditure on diabetes for 2010 and 2030. Diabetes Res Clin Pract . 2010;87(3):293–301. doi:10.1016/j.diabres.2010.01.026 20171754
   PubMed Web of Science ®Google Scholar
• Oei L , Zillikens MC , Dehghan A , et al. High bone mineral density and fracture risk in type 2 diabetes as skeletal complications of inadequate glucose control: the Rotterdam Study. Diabetes Care . 2013;36(6):1619–1628. doi:10.2337/dc12-1188 23315602
   PubMed Web of Science ®Google Scholar
• Gulcelik NE , Bayraktar M , Caglar O , Alpaslan M , Karakaya J . Mortality after hip fracture in diabetic patients. Exp Clin Endocrinol Diabetes . 2011;119(7):414–418. doi:10.1055/s-0030-1270466 21553363
   PubMed Web of Science ®Google Scholar
• Lewis R . Mineral and bone disorders in chronic kidney disease: new insights into mechanism and management. Ann Clin Biochem . 2012;49(Pt 5):432–440. doi:10.1258/acb.2012.012004 22807503
   PubMed Web of Science ®Google Scholar
• Olmos JM , Pérez-Castrillón JL , García MT , et al. Bone densitometry and biochemical bone remodeling markers in type 1 diabetes mellitus. Bone Miner . 1994;26(1):1–8. doi:10.1016/s0169-6009(08)80157-2 7950501
   PubMedGoogle Scholar
• Kanazawa I , Yamaguchi T , Yamamoto M , et al. Combination of obesity with hyperglycemia is a risk factor for the presence of vertebral fractures in type 2 diabetic men. Calcif Tissue Int . 2008;83(5):324–331. doi:10.1007/s00223-008-9178-6 18946627
   PubMed Web of Science ®Google Scholar
• Schwartz AV , Sellmeyer DE , Strotmeyer ES , et al. Diabetes and bone loss at the hip in older black and white adults. J Bone Mineral Res . 2005;20(4):596–603. doi:10.1359/JBMR.041219
   Web of Science ®Google Scholar
• Kemink SA , Hermus AR , Swinkels LM , Lutterman JA , Smals AG . Osteopenia in insulin-dependent diabetes mellitus; prevalence and aspects of pathophysiology. J Endocrinol Invest . 2000;23(5):295–303. doi:10.1007/BF03343726 10882147
   PubMed Web of Science ®Google Scholar
• Lopez-Ibarra PJ , Pastor MMC , Escobar-Jiménez F , et al. Bone mineral density at time of clinical diagnosis of adult-onset type 1 diabetes mellitus. Endocrine Pract . 2001;7(5):346–351. doi:10.4158/EP.7.5.346
   Google Scholar
• Jara A , Bover J , Felsenfeld AJ . Development of secondary hyperparathyroidism and bone disease in diabetic rats with renal failure. Kidney Int . 1995;47(6):1746–1751. doi:10.1038/ki.1995.241 7643545
   PubMed Web of Science ®Google Scholar
• Dennison EM , Syddall HE , Aihie Sayer A , et al. Type 2 diabetes mellitus is associated with increased axial bone density in men and women from the Hertfordshire Cohort Study: evidence for an indirect effect of insulin resistance? Diabetologia . 2004;47(11):1963–1968. doi:10.1007/s00125-004-1560-y 15565368
   PubMed Web of Science ®Google Scholar
• van Daele PL . Bone density in non-insulin-dependent diabetes mellitus. The Rotterdam Study. Ann Intern Med . 1995;122(6):409–414. doi:10.7326/0003-4819-122-6-199503150-00002 7856988
   PubMed Web of Science ®Google Scholar
• Ma L , Oei L , Jiang L , et al. Association between bone mineral density and type 2 diabetes mellitus: a meta-analysis of observational studies. Eur J Epidemiol . 2012;27(5):319–332. doi:10.1007/s10654-012-9674-x 22451239
   PubMed Web of Science ®Google Scholar
• Thrailkill KM , Lumpkin CK , Bunn RC , Kemp SF , Fowlkes JL . Is insulin an anabolic agent in bone? Dissecting the diabetic bone for clues. Am J Physiol Endocrinol Metab . 2005;289(5):E735–745. doi:10.1152/ajpendo.00159.2005 16215165
   PubMed Web of Science ®Google Scholar
• Raskin P , Stevenson MR , Barilla DE , Pak CY . The hypercalciuria of diabetes mellitus: its amelioration with insulin. Clin Endocrinol (Oxf) . 1978;9(4):329–335. doi:10.1111/j.1365-2265.1978.tb02218.x 214258
   PubMed Web of Science ®Google Scholar
• Tzamaloukas AH , Ing TS , Siamopoulos KC , et al. Pathophysiology and management of fluid and electrolyte disturbances in patients on chronic dialysis with severe hyperglycemia. Semin Dial . 2008;21(5):431–439. doi:10.1111/j.1525-139X.2008.00464.x 18945331
   PubMed Web of Science ®Google Scholar
• Krakauer JC , Mckenna MJ , Fenn Buderer N , et al. Bone loss and bone turnover in diabetes. Diabetes . 1995;44(7):775–782. doi:10.2337/diab.44.7.775 7789645
   PubMed Web of Science ®Google Scholar
• Thalassinos NC , Hadjiyanni P , Tzanela M , Alevizaki C , Philokiprou D . Calcium metabolism in diabetes mellitus: effect of improved blood glucose control. Diabetic Med . 1993;10(4):341–344. doi:10.1111/j.1464-5491.1993.tb00076.x 8508617
   PubMed Web of Science ®Google Scholar
• Thisted H , Johnsen SP , Rungby J . An update on the long-acting insulin analogue glargine. Basic Clin Pharmacol Toxicol . 2006;99(1):1–11. doi:10.1111/j.1742-7843.2006.pto_352.x 16867163
   PubMed Web of Science ®Google Scholar
• Bolli GB , Di Marchi RD , Park GD , Pramming S , Koivisto VA . Insulin analogues and their potential in the management of diabetes mellitus. Diabetologia . 1999;42(10):1151–1167. doi:10.1007/s001250051286 10525654
   PubMed Web of Science ®Google Scholar
• Li R , Xu W , Luo S , et al. Effect of exenatide, insulin and pioglitazone on bone metabolism in patients with newly diagnosed type 2 diabetes. Acta Diabetol . 2015;52(6):1083–1091. doi:10.1007/s00592-015-0792-2 26249206
   PubMed Web of Science ®Google Scholar
• Moseley KF . Type 2 diabetes and bone fractures. Curr Opin Endocrinol Diabetes Obes . 2012;19(2):128–135. doi:10.1097/MED.0b013e328350a6e1 22262002
   PubMedGoogle Scholar
• Hofbauer LC , Brueck CC , Singh SK , Dobnig H . Osteoporosis in patients with diabetes mellitus. J Bone Mineral Res . 2007;22(9):1317–1328. doi:10.1359/jbmr.070510
   PubMed Web of Science ®Google Scholar
• De L , van der Klift M , de Laet CEDH , et al. Bone mineral density and fracture risk in type-2 diabetes mellitus: the Rotterdam Study. Osteoporosis Int . 2005;16(12):1713–1720. doi:10.1007/s00198-005-1909-1
   PubMed Web of Science ®Google Scholar
• Abdulameer SA , Sulaiman SA , Hassali MA , Subramaniam K , Sahib MN . Osteoporosis and type 2 diabetes mellitus: what do we know, and what we can do? Patient Prefer Adherence . 2012;6:435–448. doi:10.2147/PPA.S32745 22791981
   PubMed Web of Science ®Google Scholar
• Barrett-Connor E , Holbrook TL . Sex differences in osteoporosis in older adults with non-insulin-dependent diabetes mellitus. JAMA . 1992;268(23):3333–3337. doi:10.1001/jama.1992.03490230063029 1453525
   PubMed Web of Science ®Google Scholar
• Campos Pastor MM , Lopez-Ibarra PJ , Escobar-Jimenez F , Serrano Pardo MD , Garcia-Cervigon AG . Intensive insulin therapy and bone mineral density in type 1 diabetes mellitus: a prospective study. Osteoporosis Int . 2000;11(5):455–459. doi:10.1007/s001980070114
   Web of Science ®Google Scholar
• Diamant M , Heine RJ . Thiazolidinediones in type 2 diabetes mellitus: current clinical evidence. Drugs . 2003;63(13):1373–1405. doi:10.2165/00003495-200363130-00004 12825962
   PubMed Web of Science ®Google Scholar
• Lecka-Czernik B . Bone loss in diabetes: use of antidiabetic thiazolidinediones and secondary osteoporosis. Curr Osteoporos Rep . 2010;8(4):178–184. doi:10.1007/s11914-010-0027-y 20809203
   PubMedGoogle Scholar
• Gunczler P , Lanes R , Paoli M , et al. Decreased bone mineral density and bone formation markers shortly after diagnosis of clinical type 1 diabetes mellitus. J Pediatric Endocrinol Metab . 2001;14(5):525–528. doi:10.1515/jpem.2001.14.5.525
   Web of Science ®Google Scholar
• Hamada Y . [Relationship between insulin resistance and bone metabolism]. Clin Calcium . 2009;19(9):1269–1274. Japanese.19721197
   PubMedGoogle Scholar
• Xia J , Zhong Y , Huang G , et al. The relationship between insulin resistance and osteoporosis in elderly male type 2 diabetes mellitus and diabetic nephropathy. Ann d’endocrinologie . 2012;73(6):546–551. doi:10.1016/j.ando.2012.09.009
   Web of Science ®Google Scholar
• Zhou Y , Zhu ZL , Guan XX , Hou WW , Yu HY . Reciprocal roles between caffeine and estrogen on bone via differently regulating cAMP/PKA pathway: the possible mechanism for caffeine-induced osteoporosis in women and estrogen’s antagonistic effects. Med Hypotheses . 2009;73(1):83–85. doi:10.1016/j.mehy.2009.01.029 19278793
   PubMed Web of Science ®Google Scholar
• Stage TB , Christensen M-MH , Jørgensen NR , et al. Effects of metformin, rosiglitazone and insulin on bone metabolism in patients with type 2 diabetes. Bone . 2018;112:35–41. doi:10.1016/j.bone.2018.04.004 29654849
   PubMed Web of Science ®Google Scholar
• Ivers RQ , Cumming RG , Mitchell P , Peduto AJ . Diabetes and risk of fracture: the Blue Mountains Eye Study. Diabetes Care . 2001;24(7):1198–1203. doi:10.2337/diacare.24.7.1198 11423502
   PubMed Web of Science ®Google Scholar
• Melton LJ , Leibson CL , Achenbach SJ , Therneau TM , Khosla S . Fracture risk in type 2 diabetes: update of a population-based study. J Bone Miner Res . 2008;23(8):1334–1342. doi:10.1359/jbmr.080323 18348689
   PubMed Web of Science ®Google Scholar
• Losada E , Soldevila B , Ali MS , et al. Real-world antidiabetic drug use and fracture risk in 12,277 patients with type 2 diabetes mellitus: a nested case-control study. Osteoporos Int . 2018;29(9):2079–2086. doi:10.1007/s00198-018-4581-y 29860664
   PubMed Web of Science ®Google Scholar
• Jackuliak P , Kužma M , Payer J . Effect of antidiabetic treatment on bone. Physiol Res . 2019;68(Suppl 2):S107–s120. doi:10.33549/physiolres.934297 31842574
   PubMed Web of Science ®Google Scholar
• Monami M , Cresci B , Colombini A , et al. Bone fractures and hypoglycemic treatment in type 2 diabetic patients: a case-control study. Diabetes Care . 2008;31(2):199–203. doi:10.2337/dc07-1736 18024851
   PubMed Web of Science ®Google Scholar
• Leidig-Bruckner G , Grobholz S , Bruckner T , et al. Prevalence and determinants of osteoporosis in patients with type 1 and type 2 diabetes mellitus. BMC Endocr Disord . 2014;14(1):33. doi:10.1186/1472-6823-14-33 24721668
   PubMed Web of Science ®Google Scholar
• Russo GT , Giandalia A , Romeo EL , et al. Fracture risk in type 2 diabetes: current perspectives and gender differences. Int J Endocrinol . 2016;2016:1615735. doi:10.1155/2016/1615735 28044077
   PubMed Web of Science ®Google Scholar
• Compston J . Type 2 diabetes mellitus and bone. J Intern Med . 2018;283(2):140–153. doi:10.1111/joim.12725 29265670
   PubMed Web of Science ®Google Scholar
• Leidig-Bruckner G , Ziegler R . Diabetes mellitus a risk for osteoporosis? Exp Clin Endocrinol Diabetes . 2001;109 Suppl 2:S493–514. doi:10.1055/s-2001-18605 11460594
   PubMed Web of Science ®Google Scholar
• Yao X , Xu X , Jin F , Zhu Z . The correlation of type 2 diabetes status with bone mineral density in middle-aged adults. Diabetes Metab Syndr Obes . 2020;13:3269–3276. doi:10.2147/dmso.S268592 32982357
   PubMed Web of Science ®Google Scholar
• Li C-I , Liu C-S , Lin W-Y , et al. Glycated hemoglobin level and risk of hip fracture in older people with type 2 diabetes: a competing risk analysis of Taiwan Diabetes Cohort Study. J Bone Miner Res . 2015;30(7):1338–1346. doi:10.1002/jbmr.2462 25598134
   PubMed Web of Science ®Google Scholar
• Felson DT , Zhang Y , Hannan MT , Anderson JJ . Effects of weight and body mass index on bone mineral density in men and women: the Framingham study. J Bone Mineral Res . 1993;8(5):567–573. doi:10.1002/jbmr.5650080507
   PubMed Web of Science ®Google Scholar
• Rithirangsriroj K , Panyakhamlerd K , Chaikittisilpa S , Chaiwatanarat T , Taechakraichana N . Osteoporosis in different age-groups and various body mass index (BMI) ranges in women undergoing bone mass measurement at King Chulalongkorn Memorial Hospital. J Med Assoc Thailand . 2012;95(5):644–649.
   PubMedGoogle Scholar
• Cummings SR . Appendicular bone density and age predict hip fracture in women. The Study of Osteoporotic Fractures Research Group. JAMA . 1990;263(5):665–668. doi:10.1001/jama.1990.03440050059033 2404146
   PubMed Web of Science ®Google Scholar
• Majumdar S , Genant HK , Grampp S , et al. Correlation of trabecular bone structure with age, bone mineral density, and osteoporotic status: in vivo studies in the distal radius using high resolution magnetic resonance imaging. J Bone Mineral Res . 1997;12(1):111–118. doi:10.1359/jbmr.1997.12.1.111
   Web of Science ®Google Scholar
• Tang Y , Gong L , Chen X , et al. Age-related changes in body composition and bone mineral density and their relationship with the duration of diabetes and glycaemic control in type 2 diabetes. Diabetes Metab Syndr Obes . 2020;13:4699–4710. doi:10.2147/dmso.S278425 33293843
   PubMed Web of Science ®Google Scholar
• Jiang Y , Zhang Y , Jin M , et al. Aged-related changes in body composition and association between body composition with bone mass density by body mass index in Chinese Han men over 50-year-old. PLoS One . 2015;10(6):e0130400. doi:10.1371/journal.pone.0130400 26090818
   PubMed Web of Science ®Google Scholar
• Jing Y , Hong T , Bi Y , et al. Prevalence, treatment patterns and control rates of metabolic syndrome in a Chinese diabetic population: China Cardiometabolic Registries 3B study. J Diabetes Investig . 2018;9(4):789–798. doi:10.1111/jdi.12785
   PubMed Web of Science ®Google Scholar
• Catalano A , Morabito N , Di Vieste G , et al. Phalangeal quantitative ultrasound and metabolic control in pre-menopausal women with type 1 diabetes mellitus. J Endocrinol Invest . 2013;36(5):347. doi:10.3275/8646 23027769
   PubMed Web of Science ®Google Scholar
• Holloway-Kew KL , Betson A , Rufus-Membere PG , et al. Impact microindentation in men with impaired fasting glucose and type 2 diabetes. Bone . 2021;142:115685. doi:10.1016/j.bone.2020.115685 33049369
   PubMed Web of Science ®Google Scholar
• Lui DT , Lee CH , Chau VW , et al. Potential role of fibroblast growth factor 21 in the deterioration of bone quality in impaired glucose tolerance. J Endocrinol Invest . 2021;44(3):523–530. doi:10.1007/s40618-020-01337-y 32602078
   PubMed Web of Science ®Google Scholar
• Kodama K , Tojjar D , Yamada S , et al. Ethnic differences in the relationship between insulin sensitivity and insulin response: a systematic review and meta-analysis. Diabetes Care . 2013;36(6):1789–1796. doi:10.2337/dc12-1235 23704681
   PubMed Web of Science ®Google Scholar