Associations of GWAS-Supported Non-MHC Genes with Autoimmune Thyroiditis in Patients with Type 1 Diabetes

References

• American Diabetes A. 2. Classification and diagnosis of diabetes: standards of medical care in diabetes-2021. Diabetes Care . 2021;44(Suppl 1):S15–S33. doi:10.2337/dc21-S002 33298413
   PubMed Web of Science ®Google Scholar
• Eisenbarth GS , Gottlieb PA . Autoimmune polyendocrine syndromes. N Engl J Med . 2004;350(20):2068–2079. doi:10.1056/NEJMra030158 15141045
   PubMed Web of Science ®Google Scholar
• Shun CB , Donaghue KC , Phelan H , Twigg SM , Craig ME . Thyroid autoimmunity in Type 1 diabetes: systematic review and meta-analysis. Diabet Med . 2014;31(2):126–135. doi:10.1111/dme.12318 24103027
   PubMed Web of Science ®Google Scholar
• Jin P , Huang G , Lin J , et al. High titre of antiglutamic acid decarboxylase autoantibody is a strong predictor of the development of thyroid autoimmunity in patients with type 1 diabetes and latent autoimmune diabetes in adults. Clin Endocrinol (Oxf) . 2011;74(5):587–592. doi:10.1111/j.1365-2265.2011.03976.x 21470281
   PubMed Web of Science ®Google Scholar
• Bao YK , Weide LG , Ganesan VC , et al. High prevalence of comorbid autoimmune diseases in adults with type 1 diabetes from the HealthFacts database. J Diabetes . 2019;11(4):273–279. doi:10.1111/1753-0407.12856 30226016
   PubMed Web of Science ®Google Scholar
• Mory DB , Gabbay MA , Rocco ER , et al. High frequency of vitamin D receptor gene polymorphism FokI in Brazilian Type 1 diabetes mellitus patients with clinical autoimmune thyroid disease. Diabetol Metab Syndr . 2016;8:29. doi:10.1186/s13098-016-0145-5 27011770
   PubMed Web of Science ®Google Scholar
• Vallianou N , Stratigou T , Koutroumpi S , Vlassopoulou B , Tsagarakis S , Ioannidis G . Autoimmune thyroiditis in patients with type 1 diabetes mellitus: a long-term follow-up study. Diabetes Metab Syndr . 2019;13(1):608–611. doi:10.1016/j.dsx.2018.11.048 30641774
   PubMed Web of Science ®Google Scholar
• Cardinez N , Lovblom LE , Orszag A , Cherney DZI , Perkins BA . The prevalence of autoimmune diseases in longstanding diabetes: results from the Canadian study of longevity in adults with Type 1 Diabetes. Can J Diabetes . 2020;S1499–2671(20)30422–6.
   Google Scholar
• Tomer Y , Huber A . The etiology of autoimmune thyroid disease: a story of genes and environment. J Autoimmun . 2009;32(3–4):231–239. doi:10.1016/j.jaut.2009.02.007 19307103
   PubMed Web of Science ®Google Scholar
• Tomer Y , Dolan LM , Kahaly G , et al. Genome wide identification of new genes and pathways in patients with both autoimmune thyroiditis and type 1 diabetes. J Autoimmun . 2015;60:32–39. doi:10.1016/j.jaut.2015.03.006 25936594
   PubMed Web of Science ®Google Scholar
• Quintero OL , Amador-Patarroyo MJ , Montoya-Ortiz G , Rojas-Villarraga A , Anaya JM . Autoimmune disease and gender: plausible mechanisms for the female predominance of autoimmunity. J Autoimmun . 2012;38(2–3):J109–119. doi:10.1016/j.jaut.2011.10.003 22079680
   PubMed Web of Science ®Google Scholar
• Cai TT , Zhang J , Wang X , et al. Gene-gene and gene-sex epistatic interactions of DNMT1, DNMT3A and DNMT3B in autoimmune thyroid disease. Endocr J . 2016;63(7):643–653. doi:10.1507/endocrj.EJ15-0596 27237591
   PubMed Web of Science ®Google Scholar
• Hughes T , Adler A , Merrill JT , et al. Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus. Ann Rheum Dis . 2012;71(5):694–699. doi:10.1136/annrheumdis-2011-200385 22110124
   PubMed Web of Science ®Google Scholar
• Yan CY , Ma YR , Sun F , et al. Candidate gene associations reveal sex-specific Graves’ disease risk alleles among Chinese Han populations. Mol Genet Genomic Med . 2020;8(7):e1249. doi:10.1002/mgg3.1249 32342657
   PubMed Web of Science ®Google Scholar
• Weetman AP . Autoimmune thyroid disease. Autoimmunity . 2004;37(4):337–340. doi:10.1080/08916930410001705394 15518055
   PubMed Web of Science ®Google Scholar
• Thomas G , Sinville R , Sutton S , et al. Capillary and microelectrophoretic separations of ligase detection reaction products produced from low-abundant point mutations in genomic DNA. Electrophoresis . 2004;25(10–11):1668–1677. doi:10.1002/elps.200405886 15188256
   PubMed Web of Science ®Google Scholar
• Sole X , Guino E , Valls J , Iniesta R , Moreno V . SNPStats: a web tool for the analysis of association studies. Bioinformatics . 2006;22(15):1928–1929. doi:10.1093/bioinformatics/btl268 16720584
   PubMed Web of Science ®Google Scholar
• Ward LD , Kellis M . HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. Nucleic Acids Res . 2012;40(Databaseissue):D930–934. doi:10.1093/nar/gkr917 22064851
   PubMed Web of Science ®Google Scholar
• Biondi B , Kahaly GJ , Robertson RP . Thyroid dysfunction and diabetes mellitus: two closely associated disorders. Endocr Rev . 2019;40(3):789–824.30649221
   PubMed Web of Science ®Google Scholar
• Ban Y , Tozaki T , Nakano Y . Association studies of the GPR103 and BCL2L15 genes in autoimmune thyroid disease in the Japanese Population. Front Endocrinol (Lausanne) . 2016;7:92. doi:10.3389/fendo.2016.00092 27486433
   PubMed Web of Science ®Google Scholar
• Palasca O , Santos A , Stolte C , Gorodkin J , Jensen LJ . TISSUES 2.0: an integrative web resource on mammalian tissue expression. Database (Oxford) . 2018;2018:bay028. doi:10.1093/database/bay003
   Web of Science ®Google Scholar
• El-Mehdi M , Takhlidjt S , Khiar F , et al. Glucose homeostasis is impaired in mice deficient in the neuropeptide 26RFa (QRFP). BMJ Open Diabetes Res Care . 2020;8(1):e000942. doi:10.1136/bmjdrc-2019-000942
   Web of Science ®Google Scholar
• Prevost G , Jeandel L , Arabo A , et al. Hypothalamic neuropeptide 26RFa acts as an incretin to regulate glucose homeostasis. Diabetes . 2015;64(8):2805–2816. doi:10.2337/db14-1864 25858563
   PubMed Web of Science ®Google Scholar
• Prevost G , Picot M , Le Solliec MA , et al. The neuropeptide 26RFa in the human gut and pancreas: potential involvement in glucose homeostasis. Endocr Connect . 2019;8(7):941–951. doi:10.1530/EC-19-0247 31234144
   PubMed Web of Science ®Google Scholar
• Granata R , Settanni F , Trovato L , et al. RFamide peptides 43RFa and 26RFa both promote survival of pancreatic beta-cells and human pancreatic islets but exert opposite effects on insulin secretion. Diabetes . 2014;63(7):2380–2393. doi:10.2337/db13-1522 24622796
   PubMed Web of Science ®Google Scholar
• Barrett JC , Clayton DG , Concannon P , et al. Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat Genet . 2009;41(6):703–707. doi:10.1038/ng.381 19430480
   PubMed Web of Science ®Google Scholar
• van Heel DA , Franke L , Hunt KA , et al. A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. Nat Genet . 2007;39(7):827–829. doi:10.1038/ng2058 17558408
   PubMed Web of Science ®Google Scholar
• Stahl EA , Raychaudhuri S , Remmers EF , et al. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet . 2010;42(6):508–514. doi:10.1038/ng.582 20453842
   PubMed Web of Science ®Google Scholar
• Anderson CA , Boucher G , Lees CW , et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet . 2011;43(3):246–252. doi:10.1038/ng.764 21297633
   PubMed Web of Science ®Google Scholar
• Schreiber AL , Arceneaux KP 3rd , Malbrue RA , et al. The effects of high fat diet and estradiol on hypothalamic prepro-QRFP mRNA expression in female rats. Neuropeptides . 2016;58:103–109. doi:10.1016/j.npep.2016.01.004 26823127
   PubMed Web of Science ®Google Scholar
• Balakhadze M , Giorgadze E , Lomidze M . The frequency of Langerhans islets beta-cells autoantibodies (Anti-GAD) in Georgian children and adolescents with chronic autoimmune thyroiditis. Int J Endocrinol . 2016;2016:6597091. doi:10.1155/2016/6597091 27429616
   PubMed Web of Science ®Google Scholar
• Kordonouri O , Charpentier N , Hartmann R . GADA positivity at onset of type 1 diabetes is a risk factor for the development of autoimmune thyroiditis. Pediatr Diabetes . 2011;12(1):31–33. doi:10.1111/j.1399-5448.2010.00666.x 20723098
   PubMed Web of Science ®Google Scholar