Analysis of Endocrine and Metabolic Indexes in Non-Obese Patients with Polycystic Ovary Syndrome and Its Compare with Obese Patients

References

• Delcour C , Robin G , Young J , Dewailly D . PCOS and hyperprolactinemia: what do we know in 2019? Clin Med Insights Reprod Health . 2019;13:1179558119871921. doi:10.1177/1179558119871921 31523136
   PubMed Web of Science ®Google Scholar
• Patel S . Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy. J Steroid Biochem Mol Biol . 2018;182:27‐36. doi:10.1016/j.jsbmb.2018.04.008
   Web of Science ®Google Scholar
• González F . Nutrient-induced inflammation in polycystic ovary syndrome: rolein the development of metabolic aberration and ovarian dysfunction. Semin Reprod Med . 2015;33(4):276–286. doi:10.1055/s-0035-1554918 26132932
   PubMed Web of Science ®Google Scholar
• Apridonidze T , Essah PA , Iuorno MJ , Nestler JE . Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome. J Clin Endocrinol Metab . 2005;90(4):1929–1935. doi:10.1210/jc.2004-1045 15623819
   PubMed Web of Science ®Google Scholar
• Akbarzadeh M , Naderi T , Dabbaghmanesh MH . The glucose metabolism disorder and dyslipidemia among girls with different phenotype polycystic ovary syndrome. J Res Med Sci . 2019;24:72. doi:10.4103/jrms.JRMS_804_16 31523258
   PubMed Web of Science ®Google Scholar
• Dumesic DA , Oberfield SE , Stener-Victorin E , Marshall JC , Laven JS , Legro RS . Scientific statement on the diagnostic criteria, epidemiology, pathophysiology, and molecular genetics of polycystic ovary syndrome. Endocr Rev . 2015;36(5):487–525. doi:10.1210/er.2015-1018 26426951
   PubMed Web of Science ®Google Scholar
• Satyaraddi A , Cherian KE , Kapoor N , et al. Body composition, metabolic characteristics, and insulin resistance in obese and nonobese women with polycystic ovary syndrome. J Hum Reprod Sci . 2019;12(2):78–84. doi:10.4103/jhrs.JHRS_2_19 31293320
   PubMedGoogle Scholar
• Durmus U , Duran C , Ecirli S . Visceral adiposity index levels in overweight and/or obese, and non‑obese patients with polycystic ovary syndrome and its relationship with metabolic and inflammatory parameters. J Endocrinol Invest . 2017;40(5):487–497. doi:10.1007/s40618-016-0582-x 27838846
   PubMed Web of Science ®Google Scholar
• Pinola P , Puukka K , Piltonen TT , et al. Normo- and hyperandrogenic women with polycystic ovary syndrome exhibit an adverse metabolic profile through life. Fertil Steril . 2017;107(3):788–795. doi:10.1016/j.fertnstert.2016.12.017 28089571
   PubMed Web of Science ®Google Scholar
• Feingold K , Brinton EA , Grunfeld C , et al. The Effect of Endocrine Disorders on Lipids and Lipoproteins . Endotext [Internet]. Bookshelf ID: NBK409608. South Dartmouth (MA): MDText.com, Inc.; 2000.
   Google Scholar
• Li SX , Chu QQ , Ma J , et al. Discovery of novel lipid profiles in PCOS: do insulin and androgen oppositely regulate bioactive lipid production? J Clin Endocrinol Metab . 2017;102(3):810–821. doi:10.1210/jc.2016-2692 27886515
   PubMed Web of Science ®Google Scholar
• Escobar-Morreale HF , Samino S , Insenser M , et al. Metabolic heterogeneity in polycys-tic ovary syndrome is determined by obesity: plasma metabolomic approach using gcms. Clin Chem . 2012;58(6):999–1009. doi:10.1373/clinchem.2011.176396 22427353
   PubMed Web of Science ®Google Scholar
• Palomba S , Santagni S , Falbo A , Sala GBL . Complications and challenges associated with polycystic ovary syndrome: current perspectives. Int J Women Health . 2015;31(7):745–763. doi:10.2147/IJWH.S70314
   Google Scholar
• Stepto NK , Cassar S , Joham AE , et al. Women with polycystic ovary syndrome have intrinsic insulin resistance on euglycaemic-hyperinsulaemic clamp. Hum Reprod . 2013;28(3):777–784. doi:10.1093/humrep/des463 23315061
   PubMed Web of Science ®Google Scholar
• Fenske B , Kische H , Gross S , et al. Endogenous androgens and sex hormone–binding globulin in women and risk of metabolic syndrome and type 2 diabetes. J Clin Endocrinol Metab . 2015;100:4595–4603. doi:10.1210/jc.2015-2546 26445113
   PubMed Web of Science ®Google Scholar
• Tola H , Abbas M , Alhassan EA , Shrif NE , Rida M . Assessment of the role of the anti-mullerian hormone, luteinizing hormone/follicle stimulating hormone ratio in the diagnosis of polycystic ovary syndrome in Sudanese women. Open Access Maced J Med Sci . 2018;6(7):1244–1247. doi:10.3889/oamjms.2018.260 30087729
   PubMedGoogle Scholar
• Zhao Y , Ruan X , Mueck AO . Clinical and laboratory indicators of polycystic ovary syndrome in Chinese Han nationality with different Rotterdam criteria -based phenotypes. Gynecol Endocrinol . 2016;32(2):151–156. doi:10.3109/09513590.2015.1107895 26553260
   PubMed Web of Science ®Google Scholar
• Shea JL , Wong PY , Chen Y . Free testosterone: clinical utility and important analytical aspects of measurement. Adv Clin Chem . 2014;63(47):59–84. doi:10.1016/b978-0-12-800094-6.00002-9 24783351
   PubMed Web of Science ®Google Scholar
• Martens JW , Geller DH , Arlt W , et al. Enzymatic activities of P450c17 stably expressed in fibroblasts from patients with the polycystic ovary syndrome. J Clin Endocrinol Metab . 2000;85(11):4338–4346. doi:10.1210/jcem.85.11.6971 11095477
   PubMed Web of Science ®Google Scholar
• Bremer AA , Miller WL . The serine phosphorylation hypothesis of polycystic ovary syndrome: a unifying mechanism for hyperandrogenemia and insulin resistance. Fertil Steril . 2008;89(5):1039–1048. doi:10.1016/j.fertnstert.2008.02.091 18433749
   PubMed Web of Science ®Google Scholar
• Velija-Ašimi Z . Evaluation of the association of vitamin D deficiency with gonadotropins and sex hormone in obese and non-obese women with polycystic ovary syndrome. Med Glas . 2014;11(1):170–176. PMID: 24496360.
   Google Scholar