158
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

A Novel Circ_Arf3/miR-452-5p/Mbnl1 Axis Regulates Proliferation and Expression of Fibrosis-Related Proteins of Mouse Mesangial Cells Under High Glucose

, , , &
Pages 2105-2116 | Received 06 Dec 2022, Accepted 31 Mar 2023, Published online: 11 Jul 2023

References

  • Shimizu M, Wada T. [Nephrotic syndrome in diabetic nephropathy and diabetes]. Nihon Jinzo Gakkai Shi. 2014;56:500–509. Japanese.
  • Natesan V, Kim SJ. Diabetic nephropathy - a review of risk factors, progression, mechanism, and dietary management. Biomol Ther. 2021;29:365–372. doi:10.4062/biomolther.2020.204
  • Qi C, Mao X, Zhang Z, Wu H. Classification and differential diagnosis of diabetic nephropathy. J Diabetes Res. 2017;2017:8637138. doi:10.1155/2017/8637138
  • Chen C, Gong W, Li C, et al. Sphingosine kinase 1 mediates AGEs-induced fibronectin upregulation in diabetic nephropathy. Oncotarget. 2017;8(45):78660–78676. doi:10.18632/oncotarget.20205
  • Tung C-W, Hsu Y-C, Shih Y-H, Chang P-J, Lin C-L. Glomerular mesangial cell and podocyte injuries in diabetic nephropathy. Nephrology. 2018;23(Suppl 4):32–37. doi:10.1111/nep.13451
  • Hu W, Han Q, Zhao L, Wang L. Circular RNA circRNA_15698 aggravates the extracellular matrix of diabetic nephropathy mesangial cells via miR-185/TGF-β1. J Cell Physiol. 2019;234(2):1469–1476. doi:10.1002/jcp.26959
  • Hsiao K-Y, Sun HS, Tsai S-J. Circular RNA – new member of noncoding RNA with novel functions. Exp Biol Med. 2017;242(11):1136–1141. doi:10.1177/1535370217708978
  • Mohr AM, Mott JL. Overview of microRNA biology. Semin Liver Dis. 2015;35(01):3–11. doi:10.1055/s-0034-1397344
  • Lu TX, Rothenberg ME. MicroRNA. J Allergy Clin Immunol. 2018;141(4):1202–1207. doi:10.1016/j.jaci.2017.08.034
  • Li D, Yang Y, Li ZQ, Li LC, Zhu XH. Circular RNAs: from biogenesis and function to diseases. Chin Med J. 2019;132(20):2457–2464. doi:10.1097/CM9.0000000000000465
  • Wang L, Long H, Zheng Q, et al. Circular RNA circRHOT1 promotes hepatocellular carcinoma progression by initiation of NR2F6 expression. Mol Cancer. 2019;18(1):119. doi:10.1186/s12943-019-1046-7
  • Ge X, Xi L, Wang Q, et al. Circular RNA Circ_0000064 promotes the proliferation and fibrosis of mesangial cells via miR-143 in diabetic nephropathy. Gene. 2020;758:144952. doi:10.1016/j.gene.2020.144952
  • Wang Q, Cang Z, Shen L, et al. circ_0037128/miR-17-3p/AKT3 axis promotes the development of diabetic nephropathy. Gene. 2021;765:145076. doi:10.1016/j.gene.2020.145076
  • An L, Ji D, Hu W, et al. Interference of Hsa_circ_0003928 alleviates high glucose-induced cell apoptosis and inflammation in HK-2 cells via miR-151-3p/Anxa2. Diabetes Metab Syndr Obes. 2020;13:3157–3168. doi:10.2147/DMSO.S265543
  • Liu H, Wang X, Wang ZY, Li L. Circ_0080425 inhibits cell proliferation and fibrosis in diabetic nephropathy via sponging miR-24-3p and targeting fibroblast growth factor 11. J Cell Physiol. 2020;235:4520–4529. doi:10.1002/jcp.29329
  • Glinoer D. [The medical treatment of endocrine exophthalmos]. Bull Soc Belge Ophtalmol. 1988;226:59–64. French.
  • Peng F, Gong W, Li S, et al. circRNA_010383 acts as a sponge for miR-135a, and its downregulated expression contributes to renal fibrosis in diabetic nephropathy. Diabetes. 2021;70(2):603–615. doi:10.2337/db20-0203
  • Kaur P, Kotru S, Singh S, Munshi A. miRNA signatures in diabetic retinopathy and nephropathy: delineating underlying mechanisms. J Physiol Biochem. 2022;78(1):19–37. doi:10.1007/s13105-021-00867-0
  • Zhao SM, Zhang T, Qiu Q, et al. MiRNA-337 leads to podocyte injury in mice with diabetic nephropathy. Eur Rev Med Pharmacol Sci. 2019;23(19):8485–8492. doi:10.26355/eurrev_201910_19161
  • Sun Z, Ma Y, Chen F, et al. miR-133b and miR-199b knockdown attenuate TGF-β1-induced epithelial to mesenchymal transition and renal fibrosis by targeting SIRT1 in diabetic nephropathy. Eur J Pharmacol. 2018;837:96–104. doi:10.1016/j.ejphar.2018.08.022
  • Zongqiang H, Jiapeng C, Yingpeng Z, et al. Exosomal miR-452-5p induce M2 macrophage polarization to accelerate hepatocellular carcinoma progression by targeting TIMP3. J Immunol Res. 2022;2022:1032106. doi:10.1155/2022/1032106
  • Deng M, Hu J, Tong R, et al. miR-452-5p regulates the responsiveness of intestinal epithelial cells in inflammatory bowel disease through Mcl-1. Exp Ther Med. 2021;22:813. doi:10.3892/etm.2021.10245
  • Xie C, Wu W, Tang A, Luo N, Tan Y. lncRNA GAS5/miR-452-5p reduces oxidative stress and pyroptosis of high-glucose-stimulated renal tubular cells. Diabetes Metab Syndr Obes. 2019;12:2609–2617. doi:10.2147/DMSO.S228654
  • Song XH, He N, Xing Y-T, et al. A novel age-related circular RNA Circ-ATXN2 inhibits proliferation, promotes cell death and adipogenesis in rat adipose tissue-derived stromal cells. Front Genet. 2021;12:761926. doi:10.3389/fgene.2021.761926
  • Gao AM, Yuan C, Hu AX, Liu XS. circ_ARF3 regulates the pathogenesis of osteosarcoma by sponging miR-1299 to maintain CDK6 expression. Cell Signal. 2020;72:109622. doi:10.1016/j.cellsig.2020.109622
  • Zhou TC, Li X, Chen L-J, et al. Differential expression profile of hepatic circular RNAs in chronic hepatitis B. J Viral Hepat. 2018;25:1341–1351. doi:10.1111/jvh.12944
  • Karreth FA, P P. Pandolfi, ceRNA cross-talk in cancer: when ce-bling rivalries go awry. Cancer Discov. 2013;3(10):1113–1121. doi:10.1158/2159-8290.CD-13-0202
  • Qi X, Zhang D-H, Wu N, et al. ceRNA in cancer: possible functions and clinical implications. J Med Genet. 2015;52(10):710–718. doi:10.1136/jmedgenet-2015-103334
  • Mou X, Chenv JW, Zhou DY, et al. A novel identified circular RNA, circ_0000491, aggravates the extracellular matrix of diabetic nephropathy glomerular mesangial cells through suppressing miR101b by targeting TGFbetaRI. Mol Med Rep. 2020;22(5):3785–3794. doi:10.3892/mmr.2020.11486
  • Wang X, Bai M. CircTM7SF3 contributes to oxidized low-density lipoprotein-induced apoptosis, inflammation and oxidative stress through targeting miR-206/ASPH axis in atherosclerosis cell model in vitro. BMC Cardiovasc Disord. 2021;21(1):51. doi:10.1186/s12872-020-01800-x
  • Peng F, Gong W, Li S, et al. circRNA_010383 acts as a sponge for miR-135a and its downregulated expression contributes to renal fibrosis in diabetic nephropathy. Diabetes. 2020:db200203. doi:10.2337/db200203
  • Zheng L, Liang H, Zhang Q, et al. circPTEN1, a circular RNA generated from PTEN, suppresses cancer progression through inhibition of TGF-β/Smad signaling. Mol Cancer. 2022;21(1):41. doi:10.1186/s12943-022-01495-y
  • Chen W, Cen S, Zhou X, et al. Circular RNA CircNOLC1, upregulated by NF-KappaB, promotes the progression of prostate cancer via miR-647/PAQR4 axis. Front Cell Dev Biol. 2021;8:624764. doi:10.3389/fcell.2020.624764
  • Stavast CJ, Erkeland SJ. The non-canonical aspects of microRNAs: many roads to gene regulation. Cells. 2019;8(11):1465. doi:10.3390/cells8111465
  • Lin X, Han L, Gu C, et al. MiR-452-5p promotes colorectal cancer progression by regulating an ERK/MAPK positive feedback loop. Aging. 2021;13(5):7608–7626. doi:10.18632/aging.202657
  • Zheng J, Cheng D, Wu D, et al. MiR-452-5p mediates the proliferation, migration and invasion of hepatocellular carcinoma cells via targeting COLEC10. Per Med. 2021;18(2):97–106. doi:10.2217/pme-2020-0027
  • Gao L, Zhang L-J, Li S-H, et al. Role of miR-452-5p in the tumorigenesis of prostate cancer: a study based on the Cancer Genome Atl(TCGA), Gene Expression Omnibus (GEO), and bioinformatics analysis. Pathol Res Pract. 2018;214(5):732–749. doi:10.1016/j.prp.2018.03.002
  • Su T, Hou J, Liu T, et al. MiR-34a-5p and miR-452-5p: the novel regulators of pancreatic endocrine dysfunction in diabetic Zucker rats? Int J Med Sci. 2021;18(14):3171–3181. doi:10.7150/ijms.62843
  • Itskovich SS, Gurunathan A, Clark J, et al. MBNL1 regulates essential alternative RNA splicing patterns in MLL-rearranged leukemia. Nat Commun. 2020;11(1):2369. doi:10.1038/s41467-020-15733-8
  • Cao G, Tan B, Wei S, et al. Down-regulation of MBNL1-AS1 contributes to tumorigenesis of NSCLC via sponging miR-135a-5p. Biomed Pharmacother. 2020;125:109856. doi:10.1016/j.biopha.2020.109856
  • Xu Y, Liang C, Luo Y, Zhang T. MBNL1 regulates isoproterenol-induced myocardial remodelling in vitro and in vivo. J Cell Mol Med. 2021;25(2):1100–1115. doi:10.1111/jcmm.16177
  • Jiang X, Ruan X-L, Xue Y-X, et al. Metformin reduces the senescence of renal tubular epithelial cells in diabetic nephropathy via the MBNL1/miR-130a-3p/STAT3 pathway. Oxid Med Cell Longev. 2020;2020:8708236. doi:10.1155/2020/8708236
  • Yao T, Zha D, Hu C, Wu X. Circ_0000285 promotes podocyte injury through sponging miR-654-3p and activating MAPK6 in diabetic nephropathy. Gene. 2020;747:144661. doi:10.1016/j.gene.2020.144661