The Rate of Postoperative Mortality and Renal and Respiratory Complications are Increased in Patients with Extreme Obesity Undergoing Cardiac Surgery – A Retrospective Observational Cohort Study of 8848 Patients

References

• Bell T, Stokes S, Jenkins PC, Hatcher L, Fecher AM. Prevalence of cardiovascular and respiratory complications following trauma in patients with obesity. Heart Lung. 2018;46:347–350.
   Web of Science ®Google Scholar
• Straznicky N, Grima M, Sari C, et al. The relation of glucose metabolism to left ventricular mass and function and sympathetic nervous system activity in obese subjects with metabolic syndrome. J Clin Endocrinol Metab. 2013;98:227–237.
   PubMed Web of Science ®Google Scholar
• Che L, Xu L, Wang MY, Huang YG. Obesity paradox among elderly patients with coronary artery disease undergoing non-cardiac surgery. J Geriatr Cardiol. 2018;15(9):598–604.
   PubMedGoogle Scholar
• Sansone V, Applefield RC, De Luca P, et al. Does a high-fat diet affect the development and progression of osteoarthritis in mice?: a systematic review. Bone Joint Res. 2020;8(12):582–592.
   PubMed Web of Science ®Google Scholar
• Björntorp P. Visceral obesity: a “civilization syndrome”. Obes Res. 1993;1:206–222. doi:10.1002/j.1550-8528.1993.tb00614.x
   PubMedGoogle Scholar
• Weir CB, Jan A. BMI Classification Percentile and Cut off Points. Treasure Island. FL: StatPearls, StatPearls Publishing; 2020.
   Google Scholar
• Kovac N, Grymyr LMD, Gerdts E, et al. Markers of Subclinical Atherosclerosis in Severe Obesity and One Year after Bariatric Surgery. J Clin Med. 2022;11:2237. doi:10.3390/jcm11082237
   PubMed Web of Science ®Google Scholar
• Szymocha M, Bryła M, Maniecka-Bryła I. Epidemia otyłości w XXI wieku. Zdr Publ. 2009;1192:207–212.
   Google Scholar
• WHO Export Committee. Physical Status: The Use and Interpretation of Antropometry; Report of WHO Expert Committee. WHO Technical Report Series. 312-340. Geneva: World Health Organization;1995.
   Google Scholar
• Brown CVR, Velmahos GC. The consequences of obesity on trauma, emergency surgery, and surgical critical care. World J Emerg Surg. 2006;1:27.
   PubMedGoogle Scholar
• Nashef SA, Roques F, Sharples LD, et al. EuroSCORE II. Eur J Cardiothorac Surg. 2012;41:734–744.
   PubMed Web of Science ®Google Scholar
• Bustamante-Munguira J, Herrera-Gómez F, Ruiz-álvarez M, Hernández-Aceituno A, Figuerola-Tejerina A, New Surgical A. Site Infection Risk Score: infection Risk Index in Cardiac Surgery. J Clin Med. 2019;8:480. doi:10.3390/jcm8040480
   PubMed Web of Science ®Google Scholar
• Wigfield CH, Lindsey JD, Muñoz A, Chopra PS, Edwards NM, Love RB. Is extreme obesity a risk factor for cardiac surgery? An analysis of patients with a BMI > or = 40. Eur J Cardiothorac Surg. 2006;29:434–440. doi:10.1016/j.ejcts.2006.01.016
   PubMed Web of Science ®Google Scholar
• Ghanta RK, LaPar D, Zhang Q, et al. Obesity Increases Risk‐Adjusted Morbidity, Mortality, and Cost Following Cardiac Surgery. J Am Heart Assoc. 2017;6:e003831. doi:10.1161/JAHA.116.003831
   PubMed Web of Science ®Google Scholar
• Aguiar C, MacLeod J, Yip A, et al. Impact of Obesity on Postoperative Outcomes following cardiac Surgery (The OPOS study): rationale and design of an investigator-initiated prospective study. BMJ Open. 2019;9:e023418. doi:10.1136/bmjopen-2018-023418
   PubMed Web of Science ®Google Scholar
• Gao M, Sun J, Young N, et al. Impact of Body Mass Index on Outcomes in Cardiac Surgery. J Cardiothorac Vasc Anesth. 2016;30:1308–1316. doi:10.1053/j.jvca.2016.03.002
   PubMed Web of Science ®Google Scholar
• Kambham N, Markowitz GS, Valeri AM, et al. Obesity-related glomerulopathy: an emerging epidemic. Kidney Int. 2001;59:1498–1509.
   PubMed Web of Science ®Google Scholar
• Hsu CY, McCulloch CE, Iribarren C, et al. Body mass index and risk for end-stage renal disease. Ann Intern Med. 2006;144:21–28.
   PubMed Web of Science ®Google Scholar
• Serra A, Romero R, Lopez D, et al. Renal injury in the extremely obese patients with normal renal function. Kidney Int. 2008;73:947–955.
   PubMed Web of Science ®Google Scholar
• Billings FTT, Pretorius M, Schildcrout JS, et al. Obesity and oxidative stress predict AKI after cardiac surgery. J Am Soc Nephrol. 2012;23:1221–1228.
   PubMed Web of Science ®Google Scholar
• Hertzberg D, Sartipy U, Holzmann MJ. Type 1 and type 2 diabetes mellitus and risk of acute kidney injury after coronary artery bypass grafting. Am Heart J. 2015;170:895–902.
   PubMed Web of Science ®Google Scholar
• Boly CA, Venhuizen M, Dekker NAM, Vonk ABA, Boer C, Brom CE. Comparison of Microcirculatory Perfusion in Obese and Non-Obese Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass. J Clin Med. 2021;10:469. doi:10.3390/jcm10030469
   PubMed Web of Science ®Google Scholar
• Yazdanian F, Faritous SZ, Mollasadeghi G, Farasatkish R, Ghaffari Nejad MH, Khamoushi AJ. Impact of Body Mass Index on In-Hospital Mortality and Morbidity after Coronary Artery Bypass Grafting Surgery. J Tehran Heart Cent. 2008;3:25–30.
   Google Scholar
• Krdzalic A, Kosjerina A, Jahic E, Rifatbegovic Z, Krdzalic G. Influence of remifentanil/propofol anesthesia on ventilator-associated pneumonia occurrence after major cardiac surgery. Med Arch. 2013;67:407–409.
   PubMedGoogle Scholar
• Liu T, Chen JJ, Bai XJ, Zheng GS, Gao W. The effect of obesity on outcomes in trauma patients: a meta-analysis. Injury. 2013;44:1145–1152.
   PubMed Web of Science ®Google Scholar
• Varon J, Marik P. Management of the obese critically ill patient. Crit Care Clin. 2001;17:187–200.
   PubMed Web of Science ®Google Scholar
• Ditillo M, Pandit V, Rhee P, et al. Morbid obesity predisposes trauma patients to worse outcomes: a National Trauma Data Bank analysis. J Trauma Acute Care Surg. 2014;761:176–179.
   Google Scholar
• Rose DK, Cohen MM, Wigglesworth DF, et al. Critical respiratory events in the postanesthesia care unit: patient, surgical and anesthetic factors. Anesthesiology. 1994;81:410–418.
   PubMed Web of Science ®Google Scholar
• Ray CS, Sue DY, Bray G, Hansen JE, Wasserman K. Effects of obesity on respiratory function. Am Rev Respir Dis. 1983;128:501–506.
   PubMed Web of Science ®Google Scholar
• Borracci R, Ingino C, Miranda JM. Association of body mass index with short-term outcomes after cardiac surgery: retrospective study and meta – analysis. Medicina. 2018;78(3):171–179.
   PubMed Web of Science ®Google Scholar
• Powell-Wiley TM, Poirier P, Burke LE, et al. Obesity and Cardiovascular Disease: a Scientific Statement From the American Heart Association. Circulation. 2021;143:e984–e1010.
   PubMed Web of Science ®Google Scholar