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ORIGINAL RESEARCH

Assessment of Electrolyte Imbalance and Associated Factors Among Adult Diabetic Patients Attending the University of Gondar Comprehensive Specialized Hospital, Ethiopia: A Comparative Cross-Sectional Study

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Pages 1207-1220 | Received 23 Jan 2023, Accepted 15 Apr 2023, Published online: 26 Apr 2023

References

  • Lee J. Fluid and electrolyte disturbances in critically ill patients. Electrolyte Blood Pressure. 2010;8(2):72–81. doi:10.5049/EBP.2010.8.2.72
  • Timerga A, Kelta E, Kenenisa C, Zawdie B, Habte A, Haile K. Serum electrolytes disorder and its associated factors among adults admitted with metabolic syndrome in Jimma Medical Center, South West Ethiopia: facility based crossectional study. PLoS One. 2020;15(11):E0241486. doi:10.1371/journal.pone.0241486
  • Khanduker S, Ahmed R, Khondker F, Aharama A, Afrose N, Chowdhury M. Electrolyte disturbances in patients with diabetes mellitus. Bangladesh Journal of Medical Biochemistry. 2018;10:27–35. doi:10.3329/bjmb.v10i1.36698
  • Palmer B, Clegg D. Electrolyte and acid-base disturbances in patients with diabetes mellitus. N Engl J Med. 2015;373(6):548–559. doi:10.1056/NEJMra1503102
  • Liamis G, Liberopoulos E, Barkas F, Elisaf M. Diabetes mellitus and electrolyte disorders. World J Clin Cases. 2014;2(10):488–496. doi:10.12998/wjcc.v2.i10.488
  • Woyesa S, Gebisa W, Anshebo D. Assessment of selected serum electrolyte and associated risk factors in diabetic patients. Diabetes Metabol Syndr Obes. 2019;12:2811–2817. doi:10.2147/DMSO.S233053
  • Rajagopal L, Ganesan V, Abdullah S, Arunachalam S, Kathamuthu K, Ramraj B. Exploring the interrelationship between electrolytes, anemia, and glycosylated hemoglobin (Hba1c) levels in type 2 diabetics. Asian J Pharma Clin Res. 2018;11:251–256. doi:10.22159/ajpcr.2018.v11i1.22533
  • Sadiq F, Nawaz M. Hypomagnesemia in patients with type 2 diabetes. Pak J Med Health Sci. 2014;8:983–985.
  • Kumar P, Bhargava S, Agarwal P, Garg A, Khosla A. Association of serum magnesium with type 2 diabetes mellitus and diabetic retinopathy. J Family Med Primary Care. 2019;8(5):1671. doi:10.4103/jfmpc.jfmpc_83_19
  • Vorum H, Ditzel J. Disturbance of inorganic phosphate metabolism in diabetes mellitus: its relevance to the pathogenesis of diabetic retinopathy. J Ophthalmol. 2014;2014:1–8. doi:10.1155/2014/135287
  • Rashed R, Hyassat D, Batieha A, et al. Prevalence and correlates of hypophosphatemia among type 2 diabetic patients attending the National Center for Diabetes, Endocrinology and Genetics (Ncdeg). Ann Med Surg. 2022;78:103770. doi:10.1016/j.amsu.2022.103770
  • Roglic G. Who global report on diabetes: a summary. Int J Noncommun Dis. 2016;1(1):3. doi:10.4103/2468-8827.184853
  • Sun H, Saeedi P, Karuranga S, et al. IDF diabetes atlas: global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Res Clin Pract. 2022;183:109119. doi:10.1016/j.diabres.2021.109119
  • Liamis G, Rodenburg E, Hofman A, Zietse R, Stricker B, Hoorn E. Electrolyte disorders in community subjects: prevalence and risk factors. Am J Med. 2013;126(3):256–263. doi:10.1016/j.amjmed.2012.06.037
  • Khan R, Saba F, Kausar S, Siddiqui M. Pattern of electrolyte imbalance in type 2 diabetes patients: experience from a tertiary care hospital. Pak J Med Sci. 2019;35(3):797. doi:10.12669/pjms.35.3.844
  • Arpaci D, Tocoglu A, Ergenc H, Korkmaz S, Ucar A, Tamer A. Associations of serum magnesium levels with diabetes mellitus and diabetic complications. Hippokratia. 2015;19(2):153.
  • Corona G, Giuliani C, Parenti G, et al. The economic burden of hyponatremia: systematic review and meta-analysis. Am J Med. 2016;129(8):823–35. E4. doi:10.1016/j.amjmed.2016.03.007
  • Baldrighi M, Sainaghi P, Bellan M, Bartoli E, Castello L. Hyperglycemic hyperosmolar state: a pragmatic approach to properly manage sodium derangements. Curr Diabetes Rev. 2018;14(6):534–541. doi:10.2174/1573399814666180320091451
  • Sayouba J, Asanghanwa M, Njouendou A, Kamga H, Assob J. Electrolyte imbalance in type 2 diabetes: a case study from the west region of Cameroon. Int J Res Med Sci. 2020;8:2017–2022. doi:10.18203/2320-6012.ijrms20202236
  • Circumference WW. Waist-Hip Ratio Report of a WHO Expert Consultation. Data Wlcip, Editor; 2008.
  • Al-Makki A, Dipette D, Whelton P, et al. Hypertension pharmacological treatment in adults: a World Health Organization guideline executive summary. Hypertension. 2022;79(1):293–301. doi:10.1161/HYPERTENSIONAHA.121.18192
  • Megerssa Y, Gebre M, Birru S, Goshu A, Tesfaye D. Prevalence of undiagnosed diabetes mellitus and its risk factors in selected institutions at Bishoftu Town, East Shoa, Ethiopia. J Diabetes Metab. 2013;8:S12.
  • American Diabetes Association. Standards of medical care in diabetes-2017: summary of revisions. Diabetes Care. 2017;40(Suppl 1):S4–S5. doi:10.2337/dc17-S003
  • Anago E, Medehouenou T, Akpovi C, Tchehouenou H. Electrolyte disturbances in diabetic patients in Cotonou, Benin. Int J Res Med Sci. 2016;4(12):5430–5435. doi:10.18203/2320-6012.ijrms20164223
  • Karuppan A, Sahay M, Ravindranathan R, Haripriya P, Sriram D, George M. Electrolyte disturbances among diabetic patients admitted in a multi-specialty hospital in Southern India. J Clin Diagn Res. 2019;13(2):54.
  • Ahmed S, Nur F, Ullah M, et al. Factors influencing hyponatremia in hospitalized diabetic patients- a cross sectional study. Med Today. 2014;26:04–08. doi:10.3329/medtoday.v26i1.21301
  • Ahmed S, Nur F, Ullah M, et al. Electrolyte imbalance in admitted diabetic patients: patterns and factors responsible- a cross sectional study. Kyamc J. 2017;5(1):458–466. doi:10.3329/kyamcj.v5i1.32317
  • Antony S. A study of electrolyte imbalance in diabetic patients at a teritary care hospital in Kerala. Int J Contemp Med. 2019;7(1):132. doi:10.5958/2321-1032.2019.00006.8
  • Unachukwu M, Engwa G, Nwalo F, et al. Influence of type 2 diabetes on serum electrolytes and renal function indices in patients. J Clin Diagn Res. 2018;12(6):87.
  • Kurstjens S, De Baaij J, Bouras H, Bindels R, Tack C, Hoenderop J. Determinants of hypomagnesemia in patients with type 2 diabetes mellitus. Eur J Endocrinol. 2017;176(1):11–19. doi:10.1530/EJE-16-0517
  • Waanders F, Dullaart R, Vos M, et al. Hypomagnesaemia and its determinants in a contemporary primary care cohort of persons with type 2 diabetes. Endocrine. 2020;67(1):80–86. doi:10.1007/s12020-019-02116-3
  • Paladiya R, Pitliya A, Choudhry A, et al. Association of low magnesium level with duration and severity of type 2 diabetes. Cureus. 2021;13(5):E15279. doi:10.7759/cureus.15279
  • Pokharel D, Khadka D, Sigdel M, et al. Association of serum magnesium level with poor glycemic control and renal functions in Nepalese patients with type 2 diabetes mellitus. Diabetes Metab Syndr. 2017;11:S417–S23. doi:10.1016/j.dsx.2017.03.028
  • Mustafa A, Abubaker N, Suliman A, Ibrahim M, Hamza A, Elfaki E. Assessment of electrolytes level among type 2 diabetes Sudanese patients. J Glob Biosci. 2020;9(3):6921–6926.
  • Halushko O, Boliuk M, Hypophosphatemia in patients with acute stroke and diabetes mellitus: diagnosis and treatment. Emerg Med. 2021;(2.89):53–57. doi:10.22141/2224-0586.2.89.2018.126603
  • Ditzel J, Lervang H. Disturbance of inorganic phosphate metabolism in diabetes mellitus: clinical manifestations of phosphorus-depletion syndrome during recovery from diabetic ketoacidosis. Diabetes Metabol Syndr Obes. 2010;3:319–324. doi:10.2147/DMSO.S13476
  • Ahmed S, Nur F, Ullah M, Mamun A, Aminul M. Factors precipitating hypokalemia in diabetic patients: a cross sectional study. J Enam Med Coll. 2014;4:145–150. doi:10.3329/jemc.v4i3.20940
  • Janma J, Changsirikulchai S, Sangthawan P, Thokanit N, Rattanamongkolgul S, Thinkhamrop B. Serum potassium levels in Thai patients with T2dm and Egfr greater than or equal to 90 ml/min/1.73 m2. Trends Med. 2019;19. doi:10.15761/TiM.1000178
  • Ahn C, Kang J, Jeung E. Calcium homeostasis in diabetes mellitus. J Vet Sci. 2017;18(3):261–266. doi:10.4142/jvs.2017.18.3.261
  • Al-Jameil N. Estimation of serum electrolytes in diabetes patients of Saudi region. Life Sci J. 2014;11(7):378–380.
  • Amballi A, Kayode B, Odusan O, et al. Cortisol and electrolyte levels in type 2 diabetic patients attending a state university teaching hospital, Ogun State, Nigeria. Int J Biomed Health Sci. 2019;14(2):175.
  • Talabani N. Serum electrolytes and lipid profiles in non-insulin dependent diabetes mellitus patients. Asian J Med Sci. 2014;6(3):38–41. doi:10.3126/ajms.v6i3.11088
  • Wang S, Hou X, Liu Y, et al. Serum electrolyte levels in relation to macrovascular complications in Chinese patients with diabetes mellitus. Cardiovasc Diabetol. 2013;12(1):1–10. doi:10.1186/1475-2840-12-146
  • Rajagambeeram R, Malik I, Vijayan M, Gopal N, Ranganadin P. Evaluation of serum electrolytes and their relation to glycemic status in patients with T2dm. Int J Clin Biochem Res. 2020;6:10.
  • Nwankwor H, Nwatu C, Okwara C, et al. Low serum calcium levels occur in Nigerian adults with type 2 diabetes and correlates negatively with their glycosylated hemoglobin levels: a case‑control study. Niger J Med. 2020;29(2):229–233. doi:10.4103/NJM.NJM_25_20
  • Najeeb Q, Aziz R, Hamid S. To evaluate the levels of glycated hemoglobin, serum calcium, magnesium, phosphate, uric acid and microalbuminuria in patients with newly diagnosed type 2 diabetes mellitus. Int J Res Med Sci. 2014;2(4):1462–1465. doi:10.5455/2320-6012.ijrms20141140
  • Mishra S, Padmanaban P, Deepti G, Sarkar G, Sumathi S, Toora B. Serum magnesium and dyslipidemia in type-2 diabetes mellitus. Biomed Res. 2012;23(2):295–300.
  • Winzer E, Grabovac I, Ludvik B, et al. Differences in serum magnesium levels in diabetic and non-diabetic patients following one-anastomosis gastric bypass. Nutrients. 2019;11(9):1984. doi:10.3390/nu11091984
  • Yunka T, Mogas S, Zawdie B, et al. The hidden burden of diabetes mellitus in an urban community of Southwest Ethiopia. Diabetes Metabol Syndr Obes. 2020;13:2925. doi:10.2147/DMSO.S269386
  • Pannem R, Munamala C. An observational study on effects of hypomagnesemia among critically ill patients at a tertiary care hospital. Int J Adv Med. 2018;5:1347. doi:10.18203/2349-3933.ijam20184254
  • Palmer BF, Clegg DJ. Electrolyte disturbances in patients with chronic alcohol-use disorder. N Engl J Med. 2017;377(14):1368–1377. doi:10.1056/NEJMra1704724
  • Elisaf M, Kalaitzidis R. Metabolic abnormalities in alcoholic patients: focus on acid base and electrolyte disorders. J Alcohol Drug Depend. 2015;2015:26.
  • Parmar S, Singh S, Singh G. Role of hyperglycemia in the pathogenesis of Na±/K±disturbance. Int J Res Med Sci. 2016;4(4):1167–1171. doi:10.18203/2320-6012.ijrms20160803