Role of Increased miR-222-3p Expression in Peripheral Blood and Wound Marginal Tissues of Type 2 Diabetes Mellitus Patients with Diabetic Foot Ulcer

References

• Zhang P, Lu J, Jing Y, Tang S, Zhu D, Bi Y. Global epidemiology of diabetic foot ulceration: a systematic review and meta-analysis. Ann Med. 2017;49(2):106–116. doi:10.1080/07853890.2016.1231932
   PubMed Web of Science ®Google Scholar
• Everett E, Mathioudakis N. Update on management of diabetic foot ulcers. Ann N Y Acad Sci. 2018;1411(1):153–165. doi:10.1111/nyas.13569
   PubMed Web of Science ®Google Scholar
• Saliminejad K, Khorram Khorshid HR, Soleymani Fard S, Ghaffari SH. An overview of microRNAs: biology, functions, therapeutics, and analysis methods. J Cell Physiol. 2019;234(5):5451–5465. doi:10.1002/jcp.27486
   PubMed Web of Science ®Google Scholar
• Goodarzi G, Maniati M, Qujeq D. The role of microRNAs in the healing of diabetic ulcers. Int Wound J. 2019;16(3):621–633. doi:10.1111/iwj.13070
   PubMed Web of Science ®Google Scholar
• Erener S, Marwaha A, Tan R, Panagiotopoulos C, Kieffer TJ. Profiling of circulating microRNAs in children with recent onset of type 1 diabetes. JCI Insight. 2017;2(4):e89656. doi:10.1172/jci.insight.89656
   PubMed Web of Science ®Google Scholar
• Ortega FJ, Mercader JM, Moreno-Navarrete JM, et al. Profiling of circulating microRNAs reveals common microRNAs linked to type 2 diabetes that change with insulin sensitization. Diabetes Care. 2014;37(5):1375–1383. doi:10.2337/dc13-1847
   PubMed Web of Science ®Google Scholar
• Ortega FJ, Mercader JM, Catalán V, et al. Targeting the circulating microRNA signature of obesity. Clin Chem. 2013;59(5):781–792. doi:10.1373/clinchem.2012.195776
   PubMed Web of Science ®Google Scholar
• Wang Q, Fang C, Zhao Y, Liu Z. Correlation study on serum miR-222-3p and glucose and lipid metabolism in patients with polycystic ovary syndrome. BMC Womens Health. 2022;22(1):398. doi:10.1186/s12905-022-01912-w
   PubMed Web of Science ®Google Scholar
• Tagoma A, Alnek K, Kirss A, Uibo R, Haller-Kikkatalo K. MicroRNA profiling of second trimester maternal plasma shows upregulation of miR-195-5p in patients with gestational diabetes. Gene. 2018;672:137–142. doi:10.1016/j.gene.2018.06.004
   PubMed Web of Science ®Google Scholar
• Parker DC, Wan M, Lohman K, et al. Monocyte miRNAs are associated with type 2 diabetes. Diabetes. 2022;71(4):853–861. doi:10.2337/db21-0704
   PubMed Web of Science ®Google Scholar
• Yao X, Wang Y, Wang L, Cao M, Chen A, Zhang X. Expression patterns of serum MicroRNAs related to endothelial dysfunction in patients with subclinical hypothyroidism. Front Endocrinol. 2022;13:981622. doi:10.3389/fendo.2022.981622
   PubMed Web of Science ®Google Scholar
• Wang D, Sang Y, Sun T, et al. Emerging roles and mechanisms of microRNA-222-3p in human cancer (Review). Diabetes J Oncol. 2021;58(5):20.
   Google Scholar
• Byun JS, Gardner K. Wounds that will not heal: pervasive cellular reprogramming in cancer. Am J Pathol. 2013;182(4):1055–1064. doi:10.1016/j.ajpath.2013.01.009
   PubMed Web of Science ®Google Scholar
• Suárez Y, Sessa WC. MicroRNAs as novel regulators of angiogenesis [published correction appears in Circ Res. 2009 Apr 10;104(7):e55]. Circ Res. 2009;104(4):442–454. doi:10.1161/CIRCRESAHA.108.191270
   PubMed Web of Science ®Google Scholar
• Xue Y, Wei Z, Ding H, et al. MicroRNA-19b/221/222 induces endothelial cell dysfunction via suppression of PGC-1α in the progression of atherosclerosis. Atherosclerosis. 2015;241(2):671–681. doi:10.1016/j.atherosclerosis.2015.06.031
   PubMed Web of Science ®Google Scholar
• Poliseno L, Tuccoli A, Mariani L, et al. MicroRNAs modulate the angiogenic properties of HUVECs. Blood. 2006;108(9):3068–3071. doi:10.1182/blood-2006-01-012369
   PubMed Web of Science ®Google Scholar
• Li J, Wang J, Wang Z. Circ_0006768 upregulation attenuates oxygen-glucose deprivation/reoxygenation-induced human brain microvascular endothelial cell injuries by upregulating VEZF1 via miR-222-3p inhibition. Metab Brain Dis. 2021;36(8):2521–2534. doi:10.1007/s11011-021-00775-8
   PubMed Web of Science ®Google Scholar
• Yasmeen S, Kaur S, Mirza AH, Brodin B, Pociot F, Kruuse C. miRNA-27a-3p and miRNA-222-3p as novel modulators of phosphodiesterase 3a (PDE3A) in cerebral microvascular endothelial cells. Mol Neurobiol. 2019;56(8):5304–5314. doi:10.1007/s12035-018-1446-5
   PubMed Web of Science ®Google Scholar
• Xu J, Bai S, Cao Y, et al. miRNA-221-3p in endothelial progenitor cell-derived exosomes accelerates skin wound healing in diabetic mice. Diabetes Metab Syndr Obes. 2020;13:1259–1270. doi:10.2147/DMSO.S243549
   PubMed Web of Science ®Google Scholar
• Xu M, Li Y, Tang Y, Zhao X, Xie D, Chen M. Increased expression of miR-155 in peripheral blood and wound margin tissue of type 2 diabetes mellitus patients associated with diabetic foot ulcer. Diabetes Metab Syndr Obes. 2022;15:3415–3428. doi:10.2147/DMSO.S376292
   PubMed Web of Science ®Google Scholar
• Nejad C, Pillman KA, Siddle KJ, et al. miR-222 isoforms are differentially regulated by type-I interferon. RNA. 2018;24(3):332–341. doi:10.1261/rna.064550.117
   PubMed Web of Science ®Google Scholar
• Filardi T, Catanzaro G, Grieco GE, et al. Identification and validation of miR-222-3p and miR-409-3p as plasma biomarkers in gestational diabetes mellitus sharing validated target genes involved in metabolic homeostasis. Int J Mol Sci. 2022;23(8):4276. doi:10.3390/ijms23084276
   PubMed Web of Science ®Google Scholar
• Xiang Y, Cheng J, Wang D, et al. Hyperglycemia repression of miR-24 coordinately upregulates endothelial cell expression and secretion of von Willebrand factor. Blood. 2015;125(22):3377–3387. doi:10.1182/blood-2015-01-620278
   PubMed Web of Science ®Google Scholar
• Xu J, Feng Y, Jeyaram A, Jay SM, Zou L, Chao W. Circulating plasma extracellular vesicles from septic mice induce inflammation via microRNA- and TLR7-dependent mechanisms. J Immunol. 2018;201(11):3392–3400. doi:10.4049/jimmunol.1801008
   PubMed Web of Science ®Google Scholar
• Liu XX, Wang MJ, Kan QN, et al. Kukoamine A improves mycoplasma pneumoniae pneumonia by regulating miR-222-3p/superoxide dismutase 2. Biomed Res Int. 2022;2022:2064013. doi:10.1155/2022/2064013
   PubMed Web of Science ®Google Scholar
• Yang L, Zhang X, Liu X. Long non-coding RNA GAS5 protects against Mycoplasma pneumoniae pneumonia by regulating the microRNA-222-3p/TIMP3 axis. Mol Med Rep. 2021;23(5):380. doi:10.3892/mmr.2021.12019
   PubMed Web of Science ®Google Scholar
• Xia F, Bo W, Ding J, Yu Y, Wang J. MiR-222-3p aggravates the inflammatory response by targeting SOCS1 to activate STAT3 signaling in ulcerative colitis. Turk J Gastroenterol. 2022;33(11):934–944. doi:10.5152/tjg.2022.21769
   PubMed Web of Science ®Google Scholar
• Shi L, Wei H, Zhang T, et al. A potent weighted risk model for evaluating the occurrence and severity of diabetic foot ulcers. Diabetol Metab Syndr. 2021;13(1):92. doi:10.1186/s13098-021-00711-x
   PubMed Web of Science ®Google Scholar
• Wang N, Ju S. Research advances on the mechanism of refractory healing of diabetic foot ulcer. Zhonghua Shao Shang Za Zhi. 2022;38(11):1085–1089. doi:10.3760/cma.j.cn501225-20220227-00038
   PubMedGoogle Scholar
• Zhang P, Yu J, Gui Y, Sun C, Han W. Inhibition of miRNA-222-3p relieves staphylococcal enterotoxin B-induced liver inflammatory injury by upregulating suppressors of cytokine signaling 1. Yonsei Med J. 2019;60(11):1093–1102. doi:10.3349/ymj.2019.60.11.1093
   PubMed Web of Science ®Google Scholar
• Xu X, Gao R, Li S, et al. Circular RNA circZNF292 regulates H2 O2 -induced injury in human lens epithelial HLE-B3 cells depending on the regulation of the miR-222-3p/E2F3 axis. Cell Biol Int. 2021;45(8):1757–1767. doi:10.1002/cbin.11615
   PubMed Web of Science ®Google Scholar
• Wijayatunga NN, Pahlavani M, Kalupahana NS, et al. An integrative transcriptomic approach to identify depot differences in genes and microRNAs in adipose tissues from high fat fed mice. Oncotarget. 2018;9(10):9246–9261. doi:10.18632/oncotarget.24226
   PubMedGoogle Scholar
• Wu C, Liu Z, Ma L, et al. MiRNAs regulate oxidative stress related genes via binding to the 3’ UTR and TATA-box regions: a new hypothesis for cataract pathogenesis. BMC Ophthalmol. 2017;17(1):142. doi:10.1186/s12886-017-0537-9
   PubMed Web of Science ®Google Scholar
• Gao L, Chen M, Li F. MiR-222-3p downregulation prompted the migration, invasion and recruitment of endothelial progenitor cells via ADIPOR1 expression increase-induced AMKP activation. Microvasc Res. 2021;135:104134. doi:10.1016/j.mvr.2021.104134
   PubMed Web of Science ®Google Scholar
• Singer AJ, Choi Y, Rashel M, Toussaint J, McClain SA. The effects of topical nitric oxide on healing of partial thickness porcine burns. Burns. 2018;44(2):423–428. doi:10.1016/j.burns.2017.07.017
   PubMed Web of Science ®Google Scholar
• DiPietro LA. Angiogenesis and wound repair: when enough is enough. J Leukoc Biol. 2016;100(5):979–984. doi:10.1189/jlb.4MR0316-102R
   PubMed Web of Science ®Google Scholar
• Chu C, Lei X, Li Y, et al. High expression of miR-222-3p in children with Mycoplasma pneumoniae pneumonia. Ital J Pediatr. 2019;45(1):163. doi:10.1186/s13052-019-0750-7
   PubMed Web of Science ®Google Scholar
• Heydari Z, Moudi E, Sadeghi F, et al. Circulating plasma miR222-3P status and its potential diagnostic performance in prostate cancer. J Gene Med. 2022;24(12):e3459. doi:10.1002/jgm.3459
   PubMed Web of Science ®Google Scholar
• Liu L, Chen R, Jia Z, et al. Downregulation of hsa-miR-203 in peripheral blood and wound margin tissue by negative pressure wound therapy contributes to wound healing of diabetic foot ulcers. Microvasc Res. 2022;139:104275. doi:10.1016/j.mvr.2021.104275
   PubMed Web of Science ®Google Scholar