382
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Targeted Metabolomics Analysis of Serum Amino Acids in T2DM Patients

, , , , &
Pages 203-212 | Received 03 Nov 2023, Accepted 04 Jan 2024, Published online: 10 Jan 2024

References

  • Wang SY, Li M, Lin H, et al. Amino Acids, Microbiota-Related Metabolites and the Risk of Incident Diabetes among Normoglycemic Chinese Adults: findings from the 4C Study. Cell Rep Med. 2022;3(9):100727. doi:10.1016/j.xcrm.2022.100727
  • Ahola-Olli AV, Mustelin L, Kalimeri M, et al. Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11896 young adults from Finnish cohorts. Diabetologia. 2019;62(12):2298–2309. doi:10.1007/s00125-019-05001-w
  • Yu DY, Richardson NE, Lamming DW. The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine. Cell Metab. 2021;33(5):905. doi:10.1016/j.cmet.2021.03.025
  • Thomas OC. The complex role of branched chain amino acids in diabetes and cancer. Metabolites. 2013;3(4):931–945. doi:10.3390/metabo3040931
  • Mansour A, Mohajeri-Tehrani MR, Qorbani M, et al. Effect of glutamine supplementation on cardiovascular risk factors in patients with type 2 diabetes. Nutrition. 2015;31(1):119–126. doi:10.1016/j.nut.2014.05.014
  • Vangipurapu J, Stancakova A, Smith U, et al. Nine amino acids are associated with decreased insulin secretion and elevated glucose levels in a 7.4 year follow up study of 5181 Finnish men. Diabetes. 2019;68(6):1353–1358. doi:10.2337/db18-1076
  • Yoneshiro T, Wang Q, Tajima K, et al. BCAA catabolism in brown fat controls energy homeostasis through SLC25A44. Nature. 2019;572(7771):614–619. doi:10.1038/s41586-019-1503-x
  • Yu DY, Richardson NE, Green CL, et al. The adverse metabolic effects of branched chain amino acids are mediated by isoleucine and valine. Cell Metab. 2021;33(5):1–18.
  • Zhang FY, Hu GY, Chen XY, et al. Excessive branched-chain amino acid accumulation restricts mesenchymal stem cell-based therapy efficacy in myocardial infarction. Signal Transduct Target Ther. 2022;7(1):171. doi:10.1038/s41392-022-00971-7
  • Yan DR, Duong E, Manning Fox JE, et al. A glycine insulin autocrine feedback loop enhances insulin secretion from human beta-cells and is impaired in type 2 diabetes. Diabetes. 2016;65(8):2311–2321. doi:10.2337/db15-1272
  • Li XF, Chen L, Zhu XY, et al. Effect of r-aminobutyric acid rich yogurt on insulin sensitivity in a mouse model of type 2 diabetes mellitus. J Dairy Sci. 2020;103(9):7719–7729. doi:10.3168/jds.2019-17757
  • Singh P, Gollapalli K, Mangiola S, et al. Taurine deficiency as a driver of aging. Science. 2023;380(6649):6649. doi:10.1126/science.abn9257
  • Chen W, Guo J, Zhang Y, et al. The beneficial effects of taurine in preventing metabolic syndrome. Food Funct. 2016;7(4):1849–1863. doi:10.1039/C5FO01295C
  • Tiedje KE, Stevens K, Barnes S, et al. Beta-alanine as a small molecule neurotransmitter. Neurochem Int. 2010;57(3):177–188. doi:10.1016/j.neuint.2010.06.001
  • Varanoske AN, Wells AJ, Bofey D, et al. Effects of high-dose, short-duration β-alanine supplementation on cognitive function, mood, and circulating brain-derived neurotrophic factor (BDNF) in recreationally-active males before simulated military operational stress. J Diet Suppl. 2021;18(2):147–168. doi:10.1080/19390211.2020.1733730