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CLINICAL TRIAL REPORT

New Diabetic Treatment by Alleviation of Autonomic Nervous System Dysfunction Measured as Periosteal Pressure Sensitivity at Sternum Improves Empowerment, Treatment Satisfaction, and Self-Reported Health of People with Type 2 Diabetes: A Randomized Trial

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Pages 2519-2531 | Received 03 Feb 2024, Accepted 16 May 2024, Published online: 19 Jun 2024

References

  • Global. regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the global burden of disease study 2021. Lancet. 2023;402(10397):203–234. doi:10.1016/s0140-6736(23)01301-6
  • da Rocha RB, Silva CS, Cardoso VS. Self-care in adults with type 2 diabetes mellitus: a systematic review. Curr Diabetes Rev. 2020;16(6):598–607. doi:10.2174/1573399815666190702161849
  • Krzemińska S, Lomper K, Chudiak A, Ausili D, Uchmanowicz I. The association of the level of self-care on adherence to treatment in patients diagnosed with type 2 diabetes. Acta Diabetol. 2021;58(4):437–445. doi:10.1007/s00592-020-01628-z
  • Wada E, Onoue T, Kobayashi T, et al. Flash glucose monitoring helps achieve better glycemic control than conventional self-monitoring of blood glucose in non-insulin-treated type 2 diabetes: a randomized controlled trial. BMJ Open Diabetes Res Care. 2020;8(1):e001115. doi:10.1136/bmjdrc-2019-001115
  • Gomez-Velasco DV, Almeda-Valdes P, Martagon AJ, Galan-Ramirez GA, Aguilar-Salinas CA. Empowerment of patients with type 2 diabetes: current perspectives. Diabetes Metab Syndr Obes. 2019;12:1311–1321. doi:10.2147/DMSO.S174910
  • Vinik AI, Nevoret ML, Casellini C, Parson H. Diabetic neuropathy. Endocrinol Metab Clin North Am. 2013;42(4):747–787. doi:10.1016/j.ecl.2013.06.001
  • Lundqvist MH, Almby K, Abrahamsson N, Eriksson JW. Is the brain a key player in glucose regulation and development of type 2 diabetes? Front Physiol. 2019;10:457. doi:10.3389/fphys.2019.00457
  • Spallone V. Update on the impact, diagnosis and management of cardiovascular autonomic neuropathy in diabetes: what is defined, what is new, and what is unmet. Diabetes Metab J. 2019;43(1):3–30. doi:10.4093/dmj.2018.0259
  • Faber J, Eldrup E, Selmer C, et al. Reduction of pressure pain sensitivity as novel non-pharmacological therapeutic approach to type 2 diabetes: a randomized trial. Front Neurosci. 2021;15:613858. doi:10.3389/fnins.2021.613858
  • Faber J, Ballegaard S, Ørsted N, et al. In type 2 diabetes mellitus, normalization of hemoglobin A1c accompanies reduced sensitivity to pressure at the sternum. Front Neurosci. 2023;17:1067098. doi:10.3389/fnins.2023.1067098
  • Salvini V, Accioli R, Lazzerini PE, Acampa M. Editorial: new challenges and future perspectives in autonomic neuroscience. Front Neurosci. 2023;17:1271499. doi:10.3389/fnins.2023.1271499
  • Ballegaard S, Faber J, Selmer C, et al. In ischemic heart disease, reduced sensitivity to pressure at the sternum accompanies lower mortality after five years: evidence from a randomized controlled trial. J Clin Med. 2023;12(24):7585. doi:10.3390/jcm12247585
  • Ballegaard S, Petersen PB, Gyntelberg F, Faber J. The association between pressure pain sensitivity, and answers to questionnaires estimating psychological stress level in the workplace. A feasibility study. Scand J Clin Lab Invest. 2012;72(6):459–466. doi:10.3109/00365513.2012.695023
  • Ballegaard S, Bergmann N, Karpatschof B, et al. Association between pressure pain sensitivity and autonomic function as assessed by a tilt table test. Scand J Clin Lab Invest. 2015;75(5):345–354. doi:10.3109/00365513.2015.1028095
  • Anderson RM, Fitzgerald JT, Gruppen LD, Funnell MM, Oh MS. The diabetes empowerment scale-short form (DES-SF). Diabetes Care. 2003;26(5):1641–1642. doi:10.2337/diacare.26.5.1641-a
  • Baccaro F, Novelli Poisson P, Arduin J, Hilliar V. Diabetes Treatment Satisfaction Questionnaire (DTSQ) of in non-ambulatory type 2 diabetic patients. Bol Asoc Med P R. 2016;108(1):57–62.
  • Bech P. Clinical Psychometrics. Oxford, England: Wiley-Blackwell; 2012.
  • Bergmann N, Ballegaard S, Holmager P, et al. Pressure pain sensitivity: a new method of stress measurement in patients with ischemic heart disease. Scand J Clin Lab Invest. 2013;73(5):373–379. doi:10.3109/00365513.2013.785588
  • Goldstein DS. How does homeostasis happen? Integrative physiological, systems biological, and evolutionary perspectives. Am J Physiol Regul Integr Comp Physiol. 2019;316(4):R301–r317. doi:10.1152/ajpregu.00396.2018
  • Ballegaard S, Karpatschof B, Trojaborg W, Hansen AM, Magnusson G, Petersen PB. A simple and objective marker for stress. Scand J Clin Lab Invest. 2009;69(6):713–721. doi:10.3109/00365510903042734
  • McEwen BS. Neurobiological and systemic effects of chronic stress. Chronic Stress. 2017;1. doi:10.1177/2470547017692328
  • Hedges LV, Olkin I. Statistical Methods for Meta-Analysis. Academic press; 1985.
  • Bech P. Dose-response relationship of pregabalin in patients with generalized anxiety disorder. A pooled analysis of four placebo-controlled trials. Pharmacopsychiatry. 2007;40(4):163–168. doi:10.1055/s-2007-984400
  • Baer LBM. Understanding Rating Scales and Assessment Instruments. In: Handbook of Clinical Rating Scales and Assessment in Psychiatry and Mental Health. Springer; 2010.
  • Carlson AL, Mullen DM, Bergenstal RM. Clinical use of continuous glucose monitoring in adults with type 2 diabetes. Diabetes Technol Ther. 2017;19(S2):S4–s11. doi:10.1089/dia.2017.0024
  • Gallone G, Baldetti L, Tzanis G, et al. Refractory angina: from pathophysiology to new therapeutic nonpharmacological technologies. JACC: Cardiovasc Interv. 2020;13(1):1–19. doi:10.1016/j.jcin.2019.08.055
  • Lundby L, Møller A, Buntzen S, et al. Relief of fecal incontinence by sacral nerve stimulation linked to focal brain activation. Dis Colon Rectum. 2011;54(3):318–323. doi:10.1007/DCR.0b013e31820348ac
  • Tesfaye S, Boulton AJ, Dyck PJ, et al. Diabetic neuropathies: update on definitions, diagnostic criteria, estimation of severity, and treatments. Diabetes Care. 2010;33(10):2285–2293. doi:10.2337/dc10-1303
  • Moberg KU, Handlin L, Petersson M. Neuroendocrine mechanisms involved in the physiological effects caused by skin-to-skin contact - With a particular focus on the oxytocinergic system. Infant Behav Dev. 2020;61:101482. doi:10.1016/j.infbeh.2020.101482
  • Boundy EO, Dastjerdi R, Spiegelman D, et al. Kangaroo Mother Care and Neonatal Outcomes: a Meta-analysis. Pediatrics. 2016;137(1). doi:10.1542/peds.2015-2238
  • Nencini S, Ivanusic JJ. The physiology of bone pain. how much do we really know? Front Physiol. 2016;7:157. doi:10.3389/fphys.2016.00157
  • Guemes A, Georgiou P. Review of the role of the nervous system in glucose homoeostasis and future perspectives towards the management of diabetes. Bioelectron Med. 2018;4:9. doi:10.1186/s42234-018-0009-4
  • Kaptchuk TJ, Miller FG. Placebo Effects in Medicine. N Engl J Med. 2015;373(1):8–9. doi:10.1056/NEJMp1504023