Causes and consequences of obesity: epigenetics or hypokinesis?

References

• BirdAPerceptions of epigeneticsNature20074477143396 39817522671
   PubMed Web of Science ®Google Scholar
• ChongSYoungsonNAWhitelawEHeritable germline epimutation is not the same as transgenerational epigenetic inheritanceNat Genet2007395574 575 author reply 57517460682
   PubMed Web of Science ®Google Scholar
• HerreraBMKeildsonSLindgrenCMGenetics and epigenetics of obesityMaturitas201169141 4921466928
   PubMed Web of Science ®Google Scholar
• SmithFMGarfieldASWardARegulation of growth and metabolism by imprinted genesCytogenet Genome Res20061131–4279 29116575191
   PubMed Web of Science ®Google Scholar
• FraylingTMTimpsonNJWeedonMNA common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesityScience20073165826889 89417434869
   PubMed Web of Science ®Google Scholar
• CorellaDLaiCQDemissieSAPOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart StudyJ Mol Med (Berl)2007852119 12817211608
   PubMed Web of Science ®Google Scholar
• González-SánchezJLZabenaCAMartínez-LarradMTAn SNP in the adiponectin gene is associated with decreased serum adiponectin levels and risk for impaired glucose toleranceObes Res2005135807 81215919831
   PubMedGoogle Scholar
• JiaoHArnerPGerdhemPExome sequencing followed by genotyping suggests SYPL2 as a susceptibility gene for morbid obesityEur J Hum Genet Epub201411 19
   Web of Science ®Google Scholar
• RathmannWGianiGGlobal prevalence of diabetes: estimates for the year 2000 and projections for 2030Diabetes Care200427102568 2569 author reply 256915451946
   PubMed Web of Science ®Google Scholar
• LiZBowermanSHeberDHealth ramifications of the obesity epidemicSurg Clin North Am2005854681 701 v16061080
   PubMed Web of Science ®Google Scholar
• Van GaalLFMertensILDe BlockCEMechanisms linking obesity with cardiovascular diseaseNature20064447121875 88017167476
   PubMed Web of Science ®Google Scholar
• KahnHSObesity and risk of myocardial infarction: the INTERHEART studyLancet200636795161053 105416581396
   PubMed Web of Science ®Google Scholar
• AndersonASCaswellSObesity management – an opportunity for cancer preventionSurgeon200975282 28519848061
   PubMed Web of Science ®Google Scholar
• MorimotoLMWhiteEChenZObesity, body size, and risk of postmenopausal breast cancer: the Women’s Health Initiative (United States)Cancer Causes Control2002138741 75112420953
   PubMed Web of Science ®Google Scholar
• LarssonSCWolkAObesity and colon and rectal cancer risk: a meta-analysis of prospective studiesAm J Clin Nutr2007863556 56517823417
   PubMed Web of Science ®Google Scholar
• FraynKNKarpeFFieldingBAMacdonaldIACoppackSWIntegrative physiology of human adipose tissueInt J Obes2003278875 888
   Web of Science ®Google Scholar
• LiYFrommeTSchweizerSSchöttlTKlingensporMTaking control over intracellular fatty acid levels is essential for the analysis of thermogenic function in cultured primary brown and brite/beige adipocytesEMBO Rep201415101069 107625135951
   PubMed Web of Science ®Google Scholar
• GreenbergASObinMSObesity and the role of adipose tissue in inflammation and metabolismAm J Clin Nutr2006832461S 465S16470013
   PubMed Web of Science ®Google Scholar
• SpaldingKLArnerEWestermarkPODynamics of fat cell turnover in humansNature20084537196783 78718454136
   PubMed Web of Science ®Google Scholar
• BoothFWChakravarthyMVSpangenburgEEExercise and gene expression: physiological regulation of the human genome through physical activityJ Physiol2002543Pt 2399 41112205177
   PubMed Web of Science ®Google Scholar
• ToyeAADumasMEBlancherCSubtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant miceDiabetologia20075091867 187917618414
   PubMed Web of Science ®Google Scholar
• MaesHHNealeMCEavesLJGenetic and environmental factors in relative body weight and human adiposityBehav Genet1997274325 3519519560
   PubMed Web of Science ®Google Scholar
• BrownsonRCBoehmerTKLukeDADeclining rates of physical activity in the United States: what are the contributors?Annu Rev Public Health200526421 44315760296
   PubMed Web of Science ®Google Scholar
• LedikweJHBlanckHMKettel KhanLDietary energy density is associated with energy intake and weight status in US adultsAm J Clin Nutr20068361362 136816762948
   PubMed Web of Science ®Google Scholar
• EsparzaJFoxCHarperITDaily energy expenditure in Mexican and USA Pima indians: low physical activity as a possible cause of obesityInt J Obes Relat Metab Disord200024155 5910702751
   PubMed Web of Science ®Google Scholar
• PratleyREGene-environment interactions in the pathogenesis of type 2 diabetes mellitus: lessons learned from the Pima IndiansProc Nutr Soc1998572175 1819656318
   PubMed Web of Science ®Google Scholar
• RoseboomTde RooijSPainterRThe Dutch famine and its long-term consequences for adult healthEarly Hum Dev2006828485 49116876341
   PubMed Web of Science ®Google Scholar
• PainterRCOsmondCGluckmanPHansonMPhillipsDIRoseboomTJTransgenerational effects of prenatal exposure to the Dutch famine on neonatal adiposity and health in later lifeBJOG2008115101243 124918715409
   PubMed Web of Science ®Google Scholar
• BurnJShould we sequence everyone’s genome? YesBMJ2013346f313323694691
   PubMed Web of Science ®Google Scholar
• Department of HealthThe 2009 Annual Report of the Chief Medical Officer The 2009 Annual Report of the Chief Medical OfficerLondonDepartment of Health2010
   Google Scholar
• XueYChenYAyubQ1000 Genomes Project ConsortiumDeleterious- and disease-allele prevalence in healthy individuals: insights from current predictions, mutation databases, and population-scale resequencingAm J Hum Genet20129161022 103223217326
   PubMed Web of Science ®Google Scholar
• ScholzGHFleischmannHBasal insulin combined incretin mimetic therapy with glucagon-like protein 1 receptor agonists as an upcoming option in the treatment of type 2 diabetes: a practical guide to decision makingTher Adv Endocrinol Metab20145595 12325419451
   PubMedGoogle Scholar
• PadwalRLiSKLauDCLong-term pharmacotherapy for obesity and overweightCochrane Database Syst Rev20043CD00409415266516
   PubMedGoogle Scholar
• Dramatic rise in slimming drugs prescriptions leaves NHS with £50 m billThe Daily Mail20109 20 Available from: http://www.dailymail.co.uk/health/article-1313362/Slimming-drugs-cost-NHS-50m.htmlAccessed January 3, 2015
   Google Scholar
• nhs.uk [homepage on the Internet]The NHS in England: About the National Health Service (NHS)National Health Service2015 [updated January 7, 2015; cited January 3, 2015]. http://www.nhs.uk/NHSEngland/thenhs/about/Pages/overview.aspxAccessed February 11, 2015
   Google Scholar
• FontvieilleAMRavussinEMetabolic rate and body composition of Pima Indian and Caucasian childrenCrit Rev Food Sci Nutr1993334–5363 3688357498
   PubMed Web of Science ®Google Scholar
• WatsonJDCrickFHA structure for deoxyribose nucleic acidNature19531714356737 73813054692
   PubMed Web of Science ®Google Scholar
• StrettonAOWThe first sequence. Fred Sanger and insulinGenetics20021622527 53212399368
   PubMed Web of Science ®Google Scholar
• FlinterFShould we sequence everyone’s genome? NoBMJ2013346f313223694690
   PubMed Web of Science ®Google Scholar
• KeysAAndersonJTAresuMPhysical activity and the diet in populations differing in serum cholesterolJ Clin Invest195635101173 118113367213
   PubMed Web of Science ®Google Scholar
• WrightCFMiddletonABurtonHPolicy challenges of clinical genome sequencingBMJ2013347f684524270507
   PubMed Web of Science ®Google Scholar
• BuchanDSYoungJDBoddyLMBakerJSIndependent associations between cardiorespiratory fitness, waist circumference, BMI, and clustered cardiometabolic risk in adolescentsAm J Hum Biol201426129 3524136895
   PubMed Web of Science ®Google Scholar
• DenhamJMarquesFZO’BrienBJCharcharFJExercise: putting action into our epigenomeSports Med2014442189 20924163284
   PubMed Web of Science ®Google Scholar
• IranmaneshALizarraldeGVeldhuisJDAge and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous GH in healthy menJ Clin Endocrinol Metab19917351081 10881939523
   PubMed Web of Science ®Google Scholar
• FelsingNEBraselJACooperDMEffect of low and high intensity exercise on circulating growth hormone in menJ Clin Endocrinol Metab1992751157 1621619005
   PubMed Web of Science ®Google Scholar
• RootAWRootMJClinical pharmacology of human growth hormone and its secretagoguesCurr Drug Targets Immune Endocr Metabol Disord20022127 5212477295
   PubMedGoogle Scholar
• MasudaAShibasakiTNakaharaMThe effect of glucose on growth hormone (GH)-releasing hormone-mediated GH secretion in manJ Clin Endocrinol Metab1985603523 5263919046
   PubMed Web of Science ®Google Scholar
• ScacchiMPincelliAICavagniniFGrowth hormone in obesityInt J Obes Relat Metab Disord1999233260 27110193871
   PubMed Web of Science ®Google Scholar
• KatzMLFerketichAKBroder-OldachBPhysical activity among Amish and non-Amish adults living in Ohio AppalachiaJ Community Health2012372434 44021858689
   PubMed Web of Science ®Google Scholar
• HairstonKGDucharmeJLTreuthMSComparison of BMI and physical activity between old order Amish children and non-Amish childrenDiabetes Care2013364873 87823093661
   PubMed Web of Science ®Google Scholar
• BassettDRSchneiderPLHuntingtonGEPhysical activity in an Old Order Amish communityMed Sci Sports Exerc200436179 8514707772
   PubMed Web of Science ®Google Scholar
• RoseGEnvironmental factors and disease: the man made environmentBr Med J (Clin Res Ed)19872946577963 965
   Web of Science ®Google Scholar