68
Views
13
CrossRef citations to date
0
Altmetric
Original Research

A local renal renin–angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats

, , &
Pages 1-10 | Published online: 18 Jan 2016

References

  • Bader M Tissue renin-angiotensin-aldosterone systems: targets for pharmacological therapy Annu Rev Pharmacol Toxicol 2010 50 439 465 20055710
  • Paul M Poyan Mehr A Kreutz R Physiology of local renin-angiotensin systems Physiol Rev 2006 86 3 747 803 16816138
  • Carey RM Siragy HM The intrarenal renin-angiotensin system and diabetic nephropathy Trends Endocrinol Metab 2003 14 6 274 281 12890592
  • Siragy HM Carey RM Role of the intrarenal renin-angiotensin-aldosterone system in chronic kidney disease Am J Nephrol 2010 31 6 541 550 20484892
  • Anderson S Jung FF Ingelfinger JR Renal renin-angiotensin system in diabetes: functional, immunohistochemical, and molecular biological correlations Am J Physiol 1993 265 4 Pt 2 F477 F486 8238377
  • Price DA Porter LE Gordon M The paradox of the low-renin state in diabetic nephropathy J Am Soc Nephrol 1999 10 11 2382 2391 10541298
  • Vallon V Wead LM Blantz RC Renal hemodynamics and plasma and kidney angiotensin II in established diabetes mellitus in rats: effect of sodium and salt restriction J Am Soc Nephrol 1995 5 10 1761 1767 7787143
  • Kobori H Nangaku M Navar LG Nishiyama A The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease Pharmacol Rev 2007 59 3 251 287 17878513
  • Nagai Y Yao L Kobori H Temporary angiotensin II blockade at the prediabetic stage attenuates the development of renal injury in type 2 diabetic rats J Am Soc Nephrol 2005 16 3 703 711 15647337
  • Siragy HM Awad A Abadir P Webb R The angiotensin II type 1 receptor mediates renal interstitial content of tumor necrosis factor-alpha in diabetic rats Endocrinology 2003 144 6 2229 2233 12746279
  • Zimpelmann J Kumar D Levine DZ Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat Kidney Int 2000 58 6 2320 2330 11115066
  • Peti-Peterdi J Fintha A Fuson AL Tousson A Chow RH Real-time imaging of renin release in vitro Am J Physiol Renal Physiol 2004 287 2 F329 F335 15082450
  • Krop M Danser AH Circulating versus tissue renin-angiotensin system: on the origin of (pro)renin Curr Hypertens Rep 2008 10 2 112 118 18474177
  • Braam B Mitchell KD Fox J Navar LG Proximal tubular secretion of angiotensin II in rats Am J Physiol 1993 264 5 Pt 2 F891 F898 8388654
  • Navar LG Harrison-Bernard LM Nishiyama A Kobori H Regulation of intrarenal angiotensin II in hypertension Hypertension 2002 39 2 Pt 2 316 322 11882566
  • Pohl M Kaminski H Castrop H Intrarenal renin angiotensin system revisited: role of megalin-dependent endocytosis along the proximal nephron J Biol Chem 2010 285 53 41935 41946 20966072
  • Matsusaka T Niimura F Shimizu A Liver angiotensinogen is the primary source of renal angiotensin II J Am Soc Nephrol 2012 23 7 1181 1189 22518004
  • Nguyen G Danser AH Prorenin and (pro)renin receptor: a review of available data from in vitro studies and experimental models in rodents Exp Physiol 2008 93 5 557 563 18376005
  • Onozato ML Tojo A Leiper J Fujita T Palm F Wilcox CS Expression of NG,NG-dimethylarginine dimethylaminohydrolase and protein arginine N-methyltransferase isoforms in diabetic rat kidney: effects of angiotensin II receptor blockers Diabetes 2008 57 1 172 180 17909098
  • Tojo A Onozato ML Kobayashi N Goto A Matsuoka H Fujita T Angiotensin II and oxidative stress in Dahl Salt-sensitive rat with heart failure Hypertension 2002 40 6 834 839 12468566
  • Onozato ML Tojo A Goto A Fujita T Wilcox CS Oxidative stress and nitric oxide synthase in rat diabetic nephropathy: effects of ACEI and ARB Kidney Int 2002 61 1 186 194 11786100
  • Tojo A Onozato ML Kitiyakara C Glomerular albumin filtration through podocyte cell body in puromycin aminonucleoside nephrotic rat Med Mol Morphol 2008 41 2 92 98 18592163
  • Tojo A Welch WJ Bremer V Colocalization of demethylating enzymes and NOS and functional effects of methylarginines in rat kidney Kidney Int 1997 52 6 1593 1601 9407505
  • Ookata K Tojo A Suzuki Y Localization of inward rectifier potassium channel Kir7.1 in the basolateral membrane of distal nephron and collecting duct J Am Soc Nephrol 2000 11 11 1987 1994 11053473
  • Hsieh TJ Zhang SL Filep JG Tang SS Ingelfinger JR Chan JS High glucose stimulates angiotensinogen gene expression via reactive oxygen species generation in rat kidney proximal tubular cells Endocrinology 2002 143 8 2975 2985 12130563
  • Zhang SL Filep JG Hohman TC Tang SS Ingelfinger JR Chan JS Molecular mechanisms of glucose action on angiotensinogen gene expression in rat proximal tubular cells Kidney Int 1999 55 2 454 464 9987070
  • Kobori H Ohashi N Katsurada A Urinary angiotensinogen as a potential biomarker of severity of chronic kidney diseases J Am Soc Hypertens 2008 2 5 349 354 18958182
  • van den Heuvel M Batenburg WW Jainandunsing S Urinary renin, but not angiotensinogen or aldosterone, reflects the renal renin-angiotensin-aldosterone system activity and the efficacy of renin-angiotensin-aldosterone system blockade in the kidney J Hypertens 2011 29 11 2147 2155 21941204
  • Nakano D Kobori H Burford JL Multiphoton imaging of the glomerular permeability of angiotensinogen J Am Soc Nephrol 2012 23 11 1847 1856 22997258
  • Kobori H Nishiyama A Harrison-Bernard LM Navar LG Urinary angiotensinogen as an indicator of intrarenal angiotensin status in hypertension Hypertension 2003 41 1 42 49 12511528
  • Rohrwasser A Morgan T Dillon HF Elements of a paracrine tubular renin-angiotensin system along the entire nephron Hypertension 1999 34 6 1265 1274 10601129
  • Gociman B Rohrwasser A Lantelme P Expression of angiotensinogen in proximal tubule as a function of glomerular filtration rate Kidney Int 2004 65 6 2153 2160 15149328
  • Richoux JP Cordonnier JL Bouhnik J Immunocytochemical localization of angiotensinogen in rat liver and kidney Cell Tissue Res 1983 233 2 439 451 6616576
  • Tojo A Endou H Intrarenal handling of proteins in rats using fractional micropuncture technique Am J Physiol 1992 263 4 Pt 2 F601 F606 1415732
  • Norden AG Lapsley M Lee PJ Glomerular protein sieving and implications for renal failure in Fanconi syndrome Kidney Int 2001 60 5 1885 1892 11703607
  • Admiraal PJ van Kesteren CA Danser AH Derkx FH Sluiter W Schalekamp MA Uptake and proteolytic activation of prorenin by cultured human endothelial cells J Hypertens 1999 17 5 621 629 10403605
  • van den Eijnden MM Saris JJ de Bruin RJ Prorenin accumulation and activation in human endothelial cells: importance of mannose 6-phosphate receptors Arterioscler Thromb Vasc Biol 2001 21 6 911 916 11397696
  • Mizuiri S Yoshikawa H Tanegashima M Renal ACE immuno-histochemical localization in NIDDM patients with nephropathy Am J Kidney Dis 1998 31 2 301 307 9469501
  • Mezzano S Droguett A Burgos ME Renin-angiotensin system activation and interstitial inflammation in human diabetic nephropathy Kidney Int Suppl 2003 86 S64 S70 12969130
  • Deinum J Ronn B Mathiesen E Derkx FH Hop WC Schalekamp MA Increase in serum prorenin precedes onset of microalbuminuria in patients with insulin-dependent diabetes mellitus Diabetologia 1999 42 8 1006 1010 10491762
  • Nguyen G Delarue F Burckle C Bouzhir L Giller T Sraer JD Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin J Clin Invest 2002 109 11 1417 1427 12045255
  • Huang Y Wongamorntham S Kasting J Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms Kidney Int 2006 69 1 105 113 16374430
  • Feldt S Batenburg WW Mazak I Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide Hypertension 2008 51 3 682 688 18212269
  • Ichihara A Suzuki F Nakagawa T Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice J Am Soc Nephrol 2006 17 7 1950 1961 16738017
  • Wachtell K Ibsen H Olsen MH Albuminuria and cardiovascular risk in hypertensive patients with left ventricular hypertrophy: the LIFE study Ann Intern Med 2003 139 11 901 906 14644892
  • Hillege HL Fidler V Diercks GF Urinary albumin excretion predicts cardiovascular and noncardiovascular mortality in general population Circulation 2002 106 14 1777 1782 12356629
  • Tojo A The role of the kidney in protein metabolism: the capacity of tubular lysosomal proteolysis in nephrotic syndrome Kidney Int 2013 84 5 861 863 24172729