New insights into the clinical evaluation of hereditary transthyretin amyloidosis patients: a single center’s experience

References

• HammarströmPWisemanRLPowersETKellyJWPrevention of transthyretin amyloid disease by changing protein misfolding energeticsScience2003299560771371612560553
   PubMed Web of Science ®Google Scholar
• KellyJWColonWLaiZTransthyretin quaternary and tertiary structural changes facilitate misassembly into amyloidAdv Protein Chem1997501611819338081
   PubMedGoogle Scholar
• BensonMDKincaidJCThe molecular biology and clinical features of amyloid neuropathyMuscle Nerve200736441142317554795
   PubMed Web of Science ®Google Scholar
• ConnorsLHLimAProkaevaTRoskensVACostelloCETabulation of human transthyretin (TTR) variants, 2003Amyloid200310316018414640030
   PubMed Web of Science ®Google Scholar
• JacobsonDRPastoreRDYaghoubianRVariant-sequence transthyretin (isoleucine 122) in late-onset cardiac amyloidosis in black AmericansN Engl J Med199733674664739017939
   PubMed Web of Science ®Google Scholar
• WestermarkPSlettenKJohanssonBCornwellGG3rdFibril in senile systemic amyloidosis is derived from normal transthyretinProc Natl Acad Sci U S A1990877284328452320592
   PubMed Web of Science ®Google Scholar
• UedaMAgeyamaNNakamuraSAged vervet monkeys developing transthyretin amyloidosis with the human disease-causing Ile122 allele: a valid pathological model of the human diseaseLab Invest201292347448422184092
   PubMed Web of Science ®Google Scholar
• CoelhoTSousaALourençoERamalheiraJA study of 159 Portuguese patients with familial amyloidotic polyneuropathy (FAP) whose parents were both unaffectedJ Med Genet19943142932998071954
   PubMed Web of Science ®Google Scholar
• KoikeHTanakaFHashimotoRNatural history of transthyretin Val30Met familial amyloid polyneuropathy: analysis of late-onset cases from non-endemic areasJ Neurol Neurosurg Psychiatry201283215215822228785
   PubMed Web of Science ®Google Scholar
• Planté-BordeneuveVLaluTMisrahiMGenotypic-phenotypic variations in a series of 65 patients with familial amyloid polyneuropathyNeurology19985137087149748014
   PubMed Web of Science ®Google Scholar
• HellmanUAlarconFLundgrenHESuhrOBBonaiti-PelliéCPlanté-BordeneuveVHeterogeneity of penetrance in familial amyloid polyneuropathy, ATTR Val30Met, in the Swedish populationAmyloid200815318118618925456
   PubMed Web of Science ®Google Scholar
• HörnstenRPennlertJWiklundULindqvistPJensenSMSuhrOBHeart complications in familial transthyretin amyloidosis: impact of age and genderAmyloid2010172636820462364
   PubMed Web of Science ®Google Scholar
• ArakiSKuriharaTTawaraSKuribayashiTFamilial amyloidotic polyneuropathy in JapaneseGlennerGGPinho e CostaPde FreitasAFAmyloid and AmyloidosisAmsterdamExcerpta Medica19806777
   Google Scholar
• CoutinhoPda SilvaAMLimaJKBarbosaARForty years of experience with type I amyloid neuropathy: review of 483 casesGlennerGGPinho e CostaPde FreitasAFAmyloid and AmyloidosisAmsterdamExcerpta Medica19798898
   Google Scholar
• SuhrODanielssonAHolmgrenGSteenLMalnutrition and gastrointestinal dysfunction as prognostic factors for survival in familial amyloidotic polyneuropathyJ Intern Med199423554794858182405
   PubMed Web of Science ®Google Scholar
• TashimaKSuhrOBAndoYGastrointestinal dysfunction in familial amyloidotic polyneuropathy (ATTR Val30Met): comparison of Swedish and Japanese patientsAmyloid19996212412910439119
   PubMed Web of Science ®Google Scholar
• AdamsDSamuelDGoulon-GoeauCThe course and prognostic factors of familial amyloid polyneuropathy after liver transplantationBrain2000123Pt 71495150410869060
   PubMed Web of Science ®Google Scholar
• De CarvalhoMConceiçãoIBentesCLuísMLLong-term quantitative evaluation of liver transplantation in familial amyloid polyneuropathy (Portuguese V30M)Amyloid20029212613312440485
   PubMed Web of Science ®Google Scholar
• DubreySWDavidoffRSkinnerMBergethonPLewisDFalkRHProgression of ventricular wall thickening after liver transplantation for familial amyloidosisTransplantation199764174809233704
   PubMed Web of Science ®Google Scholar
• García-HerolaAPrietoMPascualSProgression of cardiomyopathy and neuropathy after liver transplantation in a patient with familial amyloidotic polyneuropathy caused by tyrosine-77 transthyretin variantLiver Transpl Surg19995324624810226117
   PubMedGoogle Scholar
• GustafssonSIhseEHeneinMYWestermarkPLindqvistPSuhrOBAmyloid fibril composition as a predictor of development of cardiomyopathy after liver transplantation for hereditary transthyretin amyloidosisTransplantation201293101017102322395298
   PubMed Web of Science ®Google Scholar
• HörnstenRWiklundUOlofssonBOJensenSMSuhrOBLiver transplantation does not prevent the development of life-threatening arrhythmia in familial amyloidotic polyneuropathy, Portuguese-type (ATTR Val30Met) patientsTransplantation200478111211615257048
   PubMed Web of Science ®Google Scholar
• OlofssonBOBackmanCKarpKSuhrOBProgression of cardiomyopathy after liver transplantation in patients with familial amyloidotic polyneuropathy, Portuguese typeTransplantation200273574575111907421
   PubMed Web of Science ®Google Scholar
• PomfretEALewisWDJenkinsRLEffect of orthotopic liver transplantation on the progression of familial amyloidotic polyneuropathyTransplantation19986579189259565095
   PubMed Web of Science ®Google Scholar
• StangouAJHawkinsPNHeatonNDProgressive cardiac amyloidosis following liver transplantation for familial amyloid polyneuropathy: implications for amyloid fibrillogenesisTransplantation19986622292339701270
   PubMed Web of Science ®Google Scholar
• SuhrOBHerleniusGFrimanSEriczonBGLiver transplantation for hereditary transthyretin amyloidosisLiver Transpl20006326327610827225
   PubMed Web of Science ®Google Scholar
• GraziGLCesconMSalviFCombined heart and liver transplantation for familial amyloidotic neuropathy: considerations from the hepatic point of viewLiver Transpl20039998699212942463
   PubMed Web of Science ®Google Scholar
• PilatoEDell’AmoreABottaLArpesellaGCombined heart and liver transplantation for familial amyloidotic neuropathyEur J Cardiothorac Surg200732118018217449267
   PubMed Web of Science ®Google Scholar
• CoelhoTMaiaLFMartins da SilvaATafamidis for transthyretin familial amyloid polyneuropathy: a randomized, controlled trialNeurologyIn press2012
   Google Scholar
• DyckPJMeltonLJ3rdO’BrienPCServiceFJApproaches to improve epidemiological studies of diabetic neuropathy: insights from the Rochester Diabetic Neuropathy StudyDiabetes199746Suppl 2S5S89285491
   PubMed Web of Science ®Google Scholar
• BergströmJGustavssonAHellmanUAmyloid deposits in transthyretin-derived amyloidosis: cleaved transthyretin is associated with distinct amyloid morphologyJ Pathol2005206222423215810051
   PubMed Web of Science ®Google Scholar
• KoikeHAndoYUedaMDistinct characteristics of amyloid deposits in early- and late-onset transthyretin Val30Met familial amyloid polyneuropathyJ Neurol Sci20092871–217818419709674
   PubMed Web of Science ®Google Scholar
• IhseEYboASuhrOLindqvistPBackmanCWestermarkPAmyloid fibril composition is related to the phenotype of hereditary transthyretin V30M amyloidosisJ Pathol2008216225326118729067
   PubMed Web of Science ®Google Scholar
• IhseESuhrOBHellmanUWestermarkPVariation in amount of wild-type transthyretin in different fibril and tissue types in ATTR amyloidosisJ Mol Med (Berl)201189217118021107516
   PubMed Web of Science ®Google Scholar
• IhseEStangouAJHeatonNDProportion between wild-type and mutant protein in truncated compared to full-length ATTR: an analysis on transplanted transthyretin T60A amyloidosis patientsBiochem Biophys Res Commun2009379484685019118530
   PubMed Web of Science ®Google Scholar
• BlevinsGMacaulayRHarderSOculoleptomeningeal amyloidosis in a large kindred with a new transthyretin variant Tyr69HisNeurology200360101625163012771253
   PubMed Web of Science ®Google Scholar
• PetersenRBGorenHCohenMTransthyretin amyloidosis: a new mutation associated with dementiaAnn Neurol19974133073139066351
   PubMed Web of Science ®Google Scholar
• SchweitzerKEhmannDGarciaRAlportEOculoleptomeningeal amyloidosis in 3 individuals with the transthyretin variant Tyr69HisCan J Ophthalmol200944331731919491989
   PubMed Web of Science ®Google Scholar
• UemichiTUittiRJKoeppenAHDonatJRBensonMDOculoleptomeningeal amyloidosis associated with a new transthyretin variant Ser64Arch Neurol19995691152115510488818
   PubMedGoogle Scholar
• IkedaSNakazatoMAndoYSobueGFamilial transthyretin-type amyloid polyneuropathy in Japan: clinical and genetic heterogeneityNeurology20025871001100711940682
   PubMed Web of Science ®Google Scholar
• SousaAAnderssonRDruggeUHolmgrenGSandgrenOFamilial amyloidotic polyneuropathy in Sweden: geographical distribution, age of onset, and prevalenceHum Hered19934352882948406517
   PubMed Web of Science ®Google Scholar
• ZarosCGeninEHellmanUOn the origin of the transthyretin Val30Met familial amyloid polyneuropathyAnn Hum Genet200872Pt 447848418460047
   PubMed Web of Science ®Google Scholar
• KoikeHMisuKIkedaSType I (transthyretin Met30) familial amyloid polyneuropathy in Japan: early- vs late-onset formArch Neurol200259111771177612433265
   PubMedGoogle Scholar
• KoikeHMisuKSugiuraMPathology of early- vs late-onset TTR Met30 familial amyloid polyneuropathyNeurology200463112913815249622
   PubMed Web of Science ®Google Scholar
• OlssonMHellmanUPlanté-BordeneuveVJonassonJLångKSuhrOBMitochondrial haplogroup is associated with the phenotype of familial amyloidosis with polyneuropathy in Swedish and French patientsClin Genet200975216316819018796
   PubMed Web of Science ®Google Scholar
• BonaïtiBOlssonMHellmanUSuhrOBonaïti-PelliéCPlanté-BordeneuveVTTR familial amyloid polyneuropathy: does a mitochondrial polymorphism entirely explain the parent-of-origin difference in penetrance?Eur J Hum Genet201018894895220234390
   PubMed Web of Science ®Google Scholar
• GibbonsCHIlligensBMCentiJFreemanRQDIRT: quantitative direct and indirect test of sudomotor functionNeurology200870242299230418541883
   PubMed Web of Science ®Google Scholar
• NovakPQuantitative autonomic testingJ Vis Exp2011532502
   Google Scholar
• YangNCLeeMJChaoCCClinical presentations and skin denervation in amyloid neuropathy due to transthyretin Ala97SerNeurology201075653253820697105
   PubMed Web of Science ®Google Scholar
• AndoYYamashitaTTanakaYRole of nitric oxide in the peripheral vessels of patients with familial amyloidotic polyneuropathy (FAP) type IJ Auton Nerv Syst199450179857844317
   PubMedGoogle Scholar
• DyckPJZimmermanIGillenDAJohnsonDKarnesJLO’BrienPCCool, warm, and heat-pain detection thresholds: testing methods and inferences about anatomic distribution of receptorsNeurology1993438150015088351002
   PubMed Web of Science ®Google Scholar
• FruhstorferHLindblomUSchmidtWCMethod for quantitative estimation of thermal thresholds in patientsJ Neurol Neurosurg Psychiatry1976391110711075188989
   PubMed Web of Science ®Google Scholar
• GruenerGDyckPJQuantitative sensory testing: methodology, applications, and future directionsJ Clin Neurophysiol19941165685837860720
   PubMed Web of Science ®Google Scholar
• JamalGAHansenSWeirAIBallantyneJPAn improved automated method for the measurement of thermal thresholds: 1. Normal subjectsJ Neurol Neurosurg Psychiatry19854843543603998741
   PubMed Web of Science ®Google Scholar
• LinYHHsiehSCChaoCCChangYCHsiehSTInfluence of aging on thermal and vibratory thresholds of quantitative sensory testingJ Peripher Nerv Syst200510326928116221286
   PubMed Web of Science ®Google Scholar
• RolkeRBaronRMaierCQuantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): standardized protocol and reference valuesPain2006123323124316697110
   PubMed Web of Science ®Google Scholar
• SelimMMWendelschafer-CrabbGHodgesJSVariation in quantitative sensory testing and epidermal nerve fiber density in repeated measurementsPain2010151357558120851518
   PubMed Web of Science ®Google Scholar
• YarnitskyDQuantitative sensory testingMuscle Nerve19972021982049040659
   PubMed Web of Science ®Google Scholar
• YarnitskyDSprecherEThermal testing: normative data and repeatability for various test algorithmsJ Neurol Sci1994125139457964887
   PubMed Web of Science ®Google Scholar
• KandelERSchwartzJHJessellTMPrinciples of Neural Science4th edNew YorkMcGraw-Hill/Appleton and Lange2000
   Google Scholar
• SchmidtRFAltnerHFundamentals of Sensory PhysiologyNew York (NY)Springer-Verlag1978
   Google Scholar
• BecserNSandTZwartJAReliability of cephalic thermal thresholds in healthy subjectsCephalalgia19981885745829827251
   PubMed Web of Science ®Google Scholar
• ClausDHilzMJHummerINeundörferBMethods of measurement of thermal thresholdsActa Neurol Scand19877642882963687380
   PubMed Web of Science ®Google Scholar
• HeldestadVLinderJSellersjöLNordhEReproducibility and influence of test modality order on thermal perception and thermal pain thresholds in quantitative sensory testingClin Neurophysiol2010121111878188520478739
   PubMed Web of Science ®Google Scholar
• HilzMJGloriusSBerićAThermal perception thresholds: influence of determination paradigm and reference temperatureJ Neurol Sci199512921351407608727
   PubMed Web of Science ®Google Scholar
• LevyDAbrahamRReidGA comparison of two methods for measuring thermal thresholds in diabetic neuropathyJ Neurol Neurosurg Psychiatry1989529107210772795077
   PubMed Web of Science ®Google Scholar
• LowensteinLJesseKKentonKComparison of perception threshold testing and thermal-vibratory testingMuscle Nerve200837451451718067137
   PubMed Web of Science ®Google Scholar
• MeierPMBerdeCBDiCanzioJZurakowskiDSethnaNFQuantitative assessment of cutaneous thermal and vibration sensation and thermal pain detection thresholds in healthy children and adolescentsMuscle Nerve200124101339134511562914
   PubMed Web of Science ®Google Scholar
• VerdugoROchoaJLQuantitative somatosensory thermotest: a key method for functional evaluation of small calibre afferent channelsBrain1992115Pt 38939131628207
   PubMed Web of Science ®Google Scholar
• HeldestadVNordhEQuantified sensory abnormalities in early genetically verified transthyretin amyloid polyneuropathyMuscle Nerve200735218919517094098
   PubMed Web of Science ®Google Scholar
• HsuWBettegowdaCJalloGIIntramedullary spinal cord tumor surgery: can we do it without intraoperative neurophysiological monitoring?Childs Nerv Syst201026224124519902217
   PubMed Web of Science ®Google Scholar
• KortelainenPPuranenJKoivistoELähdeSSymptoms and signs of sciatica and their relation to the localization of the lumbar disc herniationSpine (Phila Pa 1976)198510188923983706
   PubMed Web of Science ®Google Scholar
• TravellJGSimonsDGMyofascial Pain and DysfunctionPhiladelphia (PA)Lippincott Williams & Wilkins1992
   Google Scholar
• VallboABHagbarthKEWallinBGMicroneurography: how the technique developed and its role in the investigation of the sympathetic nervous systemJ Appl Physiol20049641262126915016790
   PubMed Web of Science ®Google Scholar
• EslerMClinical application of noradrenaline spillover methodology: delineation of regional human sympathetic nervous responsesPharmacol Toxicol19937352432538115306
   PubMedGoogle Scholar
• LowPAClinical Autonomic Disorders: Evaluation and ManagementBoston (MA)Little Brown and Co1993
   Google Scholar
• LowPACaskeyPETuckRRFealeyRDDyckPJQuantitative sudomotor axon reflex test in normal and neuropathic subjectsAnn Neurol19831455735806316835
   PubMed Web of Science ®Google Scholar
• WangAKFealeyRDGehrkingTLLowPAPatterns of neuropathy and autonomic failure in patients with amyloidosisMayo Clin Proc200883111226123018990321
   PubMed Web of Science ®Google Scholar
• DelahayeNRouzetFSardaLImpact of liver transplantation on cardiac autonomic denervation in familial amyloid polyneuropathyMedicine (Baltimore)200685422923816862048
   PubMed Web of Science ®Google Scholar
• HörnstenRSuhrOBJensenSMWiklundUOutcome of heart rate variability and ventricular late potentials after liver transplantation for familial amyloidotic polyneuropathyAmyloid200815318719518925457
   PubMed Web of Science ®Google Scholar
• KinoshitaOHongoMSaikawaYHeart rate variability in patients with familial amyloid polyneuropathyPacing Clin Electrophysiol19972012 Pt 1294929539455756
   PubMed Web of Science ®Google Scholar
• WiklundUHörnstenRKarlssonMSuhrOBJensenSMAbnormal heart rate variability and subtle atrial arrhythmia in patients with familial amyloidotic polyneuropathyAnn Noninvasive Electrocardiol200813324925618713325
   PubMed Web of Science ®Google Scholar
• WiklundUHörnstenROlofssonBOSuhrOBCardiac autonomic function does not improve after liver transplantation for familial amyloidotic polyneuropathyAuton Neurosci20101561–212413020478749
   PubMed Web of Science ®Google Scholar
• AbeMAndoYHigashiKKanoTNon-neurogenic periodic fluctuations in heart rate and vasomotion appearing in familial amyloid polyneuropathy (FAP) type I (Met30)J Auton Nerv Syst1996601–271758884698
   PubMedGoogle Scholar
• HörnstenRSuhrOBOlofssonBOWiklundUArrhythmia: a pitfall in tests of cardiac autonomic function after liver transplantation for familial amyloidotic polyneuropathy; a long-term follow-up of Swedish patientsAmyloid20121928186
   PubMed Web of Science ®Google Scholar
• ObayashiKHörnstenRWiklundUBlood pressure overshoot after tilt reversal in patients with familial amyloidotic polyneuropathyHypertens Res201134113313820927118
   PubMed Web of Science ®Google Scholar
• ZhaoYHörnstenRLindqvistPWiklundUSuhrOBHeneinMYLeft ventricular dyssynchrony is associated with reduced heart rate variability in familial amyloidotic polyneuropathyInt J Cardiol2012155227327821056485
   PubMed Web of Science ®Google Scholar
• SuhrOBLindqvistPOlofssonBOWaldenströmABackmanCMyocardial hypertrophy and function are related to age at onset in familial amyloidotic polyneuropathyAmyloid200613315415917062381
   PubMed Web of Science ®Google Scholar
• RapezziCRivaLQuartaCCGender-related risk of myocardial involvement in systemic amyloidosisAmyloid2008151404818266120
   PubMed Web of Science ®Google Scholar
• BhandariAKNandaNCMyocardial texture characterization by two-dimensional echocardiographyAm J Cardiol19835158178256829442
   PubMed Web of Science ®Google Scholar
• FalkRHPlehnJFDeeringTSensitivity and specificity of the echocardiographic features of cardiac amyloidosisAm J Cardiol19875954184222949593
   PubMed Web of Science ®Google Scholar
• John SuttonMGStReichekNKastorJAGiulianiERComputerized M-mode echocardiographic analysis of left ventricular dysfunction in cardiac amyloidCirculation19826647907996214334
   PubMed Web of Science ®Google Scholar
• ChandrasekaranKAylwardPEFleagleSRFeasibility of identifying amyloid and hypertrophic cardiomyopathy with the use of computerized quantitative texture analysis of clinical echocardiographic dataJ Am Coll Cardiol19891348328402926037
   PubMed Web of Science ®Google Scholar
• ErikssonPBackmanCErikssonAErikssonSKarpKOlofssonBODifferentiation of cardiac amyloidosis and hypertrophic cardiomyopathy: a comparison of familial amyloidosis with polyneuropathy and hypertrophic cardiomyopathy by electrocardiography and echocardiographyActa Med Scand1987221139463565084
   PubMedGoogle Scholar
• LindqvistPOlofssonBOBackmanCSuhrOWaldenströmAPulsed tissue Doppler and strain imaging discloses early signs of infiltrative cardiac disease: a study on patients with familial amyloidotic polyneuropathyEur J Echocardiogr200671223015869906
   PubMed Web of Science ®Google Scholar
• EngvallCHeneinMHolmgrenASuhrOBMörnerSLindqvistPCan myocardial strain differentiate hypertrophic from infiltrative etiology of a thickened septum?Echocardiography201128440841521323993
   PubMed Web of Science ®Google Scholar
• MigrinoRQHarmannLWoodsTBrightMTruranSHariPIntraventricular dyssynchrony in light chain amyloidosis: a new mechanism of systolic dysfunction assessed by 3-dimensional echocardiographyCardiovasc Ultrasound200864018687125
   PubMed Web of Science ®Google Scholar
• RapezziCQuartaCCGuidalottiPLUsefulness and limitations of 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid scintigraphy in the aetiological diagnosis of amyloidotic cardiomyopathyEur J Nucl Med Mol Imaging201138347047821069320
   PubMed Web of Science ®Google Scholar
• FalkRHLeeVWRubinowASkinnerMCohenASCardiac technetium-99m pyrophosphate scintigraphy in familial amyloidosisAm J Cardiol1984548115011516093493
   PubMed Web of Science ®Google Scholar
• HongoMHirayamaJFujiiTEarly identification of amyloid heart disease by technetium-99m-pyrophosphate scintigraphy: a study with familial amyloid polyneuropathyAm Heart J198711336546623030086
   PubMed Web of Science ®Google Scholar
• PeruginiERapezziCPivaTNon-invasive evaluation of the myocardial substrate of cardiac amyloidosis by gadolinium cardiac magnetic resonanceHeart200692334334915939726
   PubMed Web of Science ®Google Scholar
• PalladiniGCampanaCKlersyCSerum N-terminal pro-brain natriuretic peptide is a sensitive marker of myocardial dysfunction in AL amyloidosisCirculation2003107192440244512719281
   PubMed Web of Science ®Google Scholar
• SuhrOBAnanIBackmanCDo troponin and B-natriuretic peptide detect cardiomyopathy in transthyretin amyloidosis?J Intern Med2008263329430118069997
   PubMed Web of Science ®Google Scholar
• PalladiniGBarassiAKlersyCThe combination of high-sensitivity cardiac troponin T (hs-cTnT) at presentation and changes in N-terminal natriuretic peptide type B (NT-proBNP) after chemotherapy best predicts survival in AL amyloidosisBlood2010116183426343020644111
   PubMed Web of Science ®Google Scholar
• ErikssonAErikssonPOlofssonBOThornellLEThe cardiac atrioventricular conduction system in familial amyloidosis with polyneuropathy: a clinico-pathologic study of six cases from northern SwedenActa Pathol Microbiol Immunol Scand A19839153433496225293
   PubMedGoogle Scholar
• ErikssonAErikssonPOlofssonBOThornellLEThe sinoatrial node in familial amyloidosis with polyneuropathy: a clinico-pathological study of nine cases from northern SwedenVirchows Arch A Pathol Anat Histopathol198440232392466322411
   PubMedGoogle Scholar
• AndoYSuhrOBAutonomic dysfunction in familial amyloidotic polyneuropathy (FAP)Amyloid19985428830010036588
   PubMed Web of Science ®Google Scholar
• NiklassonUOlofssonBOBjerlePAutonomic neuropathy in familial amyloidotic polyneuropathy: a clinical study based on heart rate variabilityActa Neurol Scand19897931821872718736
   PubMed Web of Science ®Google Scholar
• BeckmanABjerlePOlofssonBElectrocardiographic findings in familial amyloidotic polyneuropathyAm J Noninvas Cardiol19926192196
   Google Scholar
• De FreitasAFThe heart in Portuguese amyloidosisPostgrad Med J1986627286016053774701
   PubMed Web of Science ®Google Scholar
• De FreitasAFBarbedoAConduction disturbances in 190 patients with familial amyloidotic polyneuropathy (Andrade’s type)Adv Cardiol197821206209202146
   PubMedGoogle Scholar
• SawayamaTKuriharaTArakiSNoninvasive cardiovascular findings in familial amyloid polyneuropathyBr Heart J1978401112881292718770
   PubMedGoogle Scholar
• OkamotoSHörnstenRObayashiKWijayatungaPSuhrOBContinuous development of arrhythmia is observed in Swedish transplant patients with familial amyloidotic polyneuropathy (amyloidogenic transthyretin Val30Met variant)Liver Transpl201117212212821280184
   PubMed Web of Science ®Google Scholar
• HörnstenRWiklundUSuhrOBJensenSMVentricular late potentials in familial amyloidotic polyneuropathyJ Electrocardiol2006391576216387053
   PubMed Web of Science ®Google Scholar
• AnanIEl-SalhyMAndoYColonic enteric nervous system in patients with familial amyloidotic neuropathyActa Neuropathol1999981485410412800
   PubMed Web of Science ®Google Scholar
• AnanIEl-salhyMAndoYTerazakiHSuhrOBComparison of amyloid deposits and infiltration of enteric nervous system in the upper with those in the lower gastrointestinal tract in patients with familial amyloidotic polyneuropathyActa Neuropathol2001102322723211585246
   PubMed Web of Science ®Google Scholar
• SuhrOBEriczonBGFrimanSLong-term follow-up of survival of liver transplant recipients with familial amyloid polyneuropathy (Portuguese type)Liver Transpl20028978779412200779
   PubMed Web of Science ®Google Scholar
• BerkJLDyckPJObiciLThe diflunisal trial: update on study drug tolerance and disease progressionAmyloid201118Suppl 119119222080762
   PubMed Web of Science ®Google Scholar
• LångKWikströmLDanielssonATashimaKSuhrOBOutcome of gastrointestinal complications after liver transplantation for familial amyloidotic polyneuropathyScand J Gastroenterol200035998598911063162
   PubMed Web of Science ®Google Scholar
• LobatoLBeirãoISilvaMEnd-stage renal disease and dialysis in hereditary amyloidosis TTR V30M: presentation, survival and prognostic factorsAmyloid2004111273715185496
   PubMed Web of Science ®Google Scholar
• LobatoLVenturaABeirãoIEnd-stage renal disease in familial amyloidosis ATTR Val30Met: a definitive indication to combined liver-kidney transplantationTransplant Proc20033531116112012947881
   PubMed Web of Science ®Google Scholar
• NowakGSuhrOBWikströmLWilczekHEriczonBGThe long-term impact of liver transplantation on kidney function in familial amyloidotic polyneuropathy patientsTranspl Int200518111111515612992
   PubMed Web of Science ®Google Scholar
• AndoEAndoYOkamuraRUchinoMAndoMNegiAOcular manifestations of familial amyloidotic polyneuropathy type I: long-term follow upBr J Ophthalmol19978142952989215058
   PubMed Web of Science ®Google Scholar
• AndoEAndoYHaraokaKOcular amyloid involvement after liver transplantation for polyneuropathyAnn Intern Med20011351093193211712896
   PubMed Web of Science ®Google Scholar
• SandgrenOKjellgrenDSuhrOBOcular manifestations in liver transplant recipients with familial amyloid polyneuropathyActa Ophthalmol200886552052418435819
   PubMed Web of Science ®Google Scholar
• SvendsenIHSteensgaard-HansenFNordvågBYA clinical, echocardiographic and genetic characterization of a Danish kindred with familial amyloid transthyretin methionine 111 linked cardiomyopathyEur Heart J19981957827899717013
   PubMed Web of Science ®Google Scholar
• SuhrOBAndersenOAronssonTReport of five rare or previously unknown amyloidogenic transthyretin mutations disclosed in SwedenAmyloid200916420821419922332
   PubMed Web of Science ®Google Scholar
• BuxbaumJNYeZReixachNTransthyretin protects Alzheimer’s mice from the behavioral and biochemical effects of Abeta toxicityProc Natl Acad Sci U S A200810572681268618272491
   PubMed Web of Science ®Google Scholar
• EpiskopouVMaedaSNishiguchiSDisruption of the transthyretin gene results in mice with depressed levels of plasma retinol and thyroid hormoneProc Natl Acad Sci U S A1993906237523798384721
   PubMed Web of Science ®Google Scholar
• BodinKEllmerichSKahanMCAntibodies to human serum amyloid P component eliminate visceral amyloid depositsNature20104687320939720962779
   PubMed Web of Science ®Google Scholar
• CoelhoTSuhrOBAdamsDPhase I safety, pharmacokinetic and pharmacodynamics results for ALN-TTR01, a novel RNAi therapeutic for the treatment of transthyretin amyloidosis (abstract)VIIIth International Symposium on Familial Amyloidotic PolyneuropathyKumamoto, Japan2011P62
   Google Scholar
• MoniaBAckermanEGuoSBensonMDClinical development of an antisense therapy for the treatment of transthyretin-associated polyneuropathy (abstract)VIIIth International Symposium on Familial Amyloidotic PolyneuropathyKumamoto, Japan2011P64
   Google Scholar
• GillmoreJDTennentGAHutchinsonWLSustained pharmacological depletion of serum amyloid P component in patients with systemic amyloidosisBr J Haematol2010148576076720064157
   PubMed Web of Science ®Google Scholar
• CardosoIMerliniGSaraivaMJ4′-Iodo-4′-deoxydoxorubicin and tetracyclines disrupt transthyretin amyloid fibrils in vitro producing noncytotoxic species: screening for TTR fibril disruptersFASEB J200317880380912724338
   PubMed Web of Science ®Google Scholar
• CardosoIMartinsDRibeiroTMerliniGSaraivaMJSynergy of combined doxycycline/TUDCA treatment in lowering transthyretin deposition and associated biomarkers: studies in FAP mouse modelsJ Transl Med201087420673327
   PubMed Web of Science ®Google Scholar