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Original Research

The effect of a mesenchymal stem cell conditioned medium fraction on morphological characteristics of hepatocytes in acetaminophen-induced acute liver failure: a preliminary study

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Pages 89-96 | Published online: 19 Jul 2019

References

  • Lee WM. Drug-induced acute liver failure. Clin Liver Dis. 2013;17:575–586. doi:10.1016/j.cld.2013.07.00124099019
  • Zimmerman HJ, Maddrey WC. Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure. Hepatology. 1995;22:767–773. doi:10.1002/(ISSN)1527-33507657281
  • Wootton FT, Lee WM. Acetaminophen hepatotoxicity in the alcoholic. South Med J. 1990;83:1047–1049. doi:10.1097/00007611-199009000-000172402650
  • Sandilands EA, Bateman DN. Adverse reactions associated with acetylcysteine. Clin Toxicol. 2009;47:81–88. doi:10.1080/15563650802665587
  • Saito C, Zwingmann C, Jaeschke H. Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine. Hepatology. 2010;51:246–254. doi:10.1002/hep.2326719821517
  • Salomone F, Barbagallo I, Puzzo L, Piazza C, Li Volti G. Efficacy of adipose tissue-mesenchymal stem cell transplantation in rats with acetaminophen liver injury. Stem Cell Res. 2013;11(3):1037–1044. doi:10.1016/j.scr.2013.07.00323954692
  • Stock P, Brückner S, Winkler S, Dollinger MM, Christ B. Human bone marrow mesenchymal stem cell-derived hepatocytes improve the mouse liver after acute acetaminophen intoxication by preventing progress of injury. Int J Mol Sci. 2014;15:7004–7028. doi:10.3390/ijms1504700424758938
  • Khubutiya MS, Vagabov AV, Temnov AA, Sklifas AN. Paracrine mechanisms of proliferative, anti-apoptotic and anti-inflammatory effects of mesenchymal stromal cells in models of acute organ injury. Cytotherapy. 2014;16(5):579–585. doi:10.1016/j.jcyt.2013.07.01724113425
  • Temnov AA, Vagabov AV, Sklifas AN, et al. The role of mesenchymal stromal cells in the repair of acute organ injury. In: Atkinson K, editor. The Biology and Therapeutic Application of Mesenchymal Cells Blackwell. Hoboken: Blackwell (John Wiley & Sons); 2016:496–523.
  • Lee JW, Fang X, Gupta N, Serikov V, Matthay MA. Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung. Pnas. 2009;106(38):16357–16362. doi:10.1073/pnas.090799610619721001
  • MSh K, Temnov AA, Vagabov AV, et al. Effect of conditioned medium and bone marrow stem cell lysate on the course of acetaminophen-induced liver failure. Bull Exp Biol Med. 2015;159(1):118–123. doi:10.1007/s10517-015-2905-x26033600
  • Yagi H, Soto-Gutierrez A, Navarro-Alvarez N, et al. Reactive bone marrow stromal cells attenuate systemic inflammation via sTNFR1. Mol Ther. 2010;18(10):1857–1864. doi:10.1038/mt.2010.15520664529
  • Kosyreva AM, Simonova EY. Histophysiology of the immune system of Wistar rats at delayed terms after ovariectomy. Bull Exp Biol Med. 2013;155(5):697–700.24288743
  • Ryu KH, Kim SY, Kim YR, et al. Tonsil-derived mesenchymal stem cells alleviate concanavalin A-induced acute liver injury. Exp Cell Res. 2014;326(1):143–154. doi:10.1016/j.yexcr.2014.06.00724954408
  • Sundin M, Orvell C, Rasmusson I, Sundberg B, Ringdén O, Le Blanc K. Mesenchymal stem cells are susceptible to human herpes viruses, but viral DNA cannot be detected in the healthy seropositive individual. Bone Marrow Transplant. 2006;37(11):1051–1059. doi:10.1038/sj.bmt.170536816604097
  • Amariglio N, Hirshberg A, Scheithauer BW, et al. Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient. PLoSMed. 2009;6(2):e1000029.
  • Gieseke F, Böhringer J, Bussolari R, Dominici M, Handgretinger R, Müller I. Human multipotent mesenchymal stromal cells use galectin-1 to inhibit immune effectors cells. Blood. 2010;116(19):3770–3779. doi:10.1182/blood-2010-02-27077720644118
  • Lepelletier Y, Lecour BA, Renand A, et al. Galectin-1 and semaphorin-3A are two soluble factors conferring T-cell immunosuppression to bone marrow mesenchymal stem cell. Stem Cells Dev. 2010;9(7):1075–1079. doi:10.1089/scd.2009.0212
  • Holmgren A. Thioredoxin and glutaredoxin systems. J.Biol.Chem. 1989;264:13963–13966.2668278
  • Nakamura T, Nakamura H, Hoshino T, Ueda S, Wada H, Yodoi J. Redox regulation of lung inflammation by thioredoxin. Antioxid Redox Signaling. 2005;7:60–71. doi:10.1089/ars.2005.7.60
  • Nakamura H, Herzenberg LA, Bai J, et al. Circulating thioredoxin suppresses lipopolysaccharide-induced neutrophil chemotaxis. Proc Natl Acad Sci U S A. 2001;98:15143–15148. doi:10.1073/pnas.19149879811742067
  • Okuyama H, Nakamura H, Shimahara Y, et al. Overexpression of thioredoxin prevents acute hepatitis caused by thioacetamide or lipopolysaccharide in mice. Hepatology. 2003;37:1015–1025. doi:10.1053/jhep.2003.5020312717382
  • Tanaka R, Ishima Y, Maeda H, et al. Albumin fusion prolongs the antioxidant and anti-inflammatory activities of thioredoxin in mice with acetaminophen-induced hepatitis. Mol Pharm. 2014;11(4):1228–1238. doi:10.1021/mp400690v24576052
  • Bourdi M, Reilly TP, Elkahloun AG, George JW, Pohl LR. Macrophage migration inhibitory factor in drug-induced liver injury: a role in susceptibility and stress responsiveness. Biochem Biophys Res Commun. 2002;294(2):225–230. doi:10.1016/S0006-291X(02)00466-712051698
  • Xia W, Xie C, Jiang M, Hou M. Improved survival of mesenchymal stem cells by macrophage migration inhibitory factor. Mol Cell Biochem. 2015;404(1–2):11–24. doi:10.1007/s11010-015-2361-y25701358