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Review

Renoprotection, renin inhibition, and blood pressure control: the impact of aliskiren on integrated blood pressure control

Pages 133-144 | Published online: 05 Oct 2010

References

  • TraubeLUeber den zusammenhang von herz und nierenkrankeiten. Page IH. Effect on renal efficiency of lowering blood pressure in cases of essential hypertension and nephritisJ Clin Invest19341390916694258
  • KlagMJWheltonPKRandallBLBlood pressure and end-stage renal disease in menN Engl J Med1996334113187494564
  • TextorSCRenal Parenchymal disease and hypertension atlas of diseases of the kidneySchrierRWISN Commission on Nephrology Informatics and NKF cyberNephrology20013 Chapter 2.4, (Figure 2.7).
  • SmithMCDunnMJHypertension in renal parenchymal diseaseLaraghJHBrennerBMHypertension: Pathophysiology, Diagnosis and ManagementNew YorkRaven Press199520812102
  • VanhouttePMBoulangerCMEndothelium-dependent responses in hypertensionHypertens Res19951887987584924
  • LüscherTFBockHAThe endothelial L-arginine/nitric oxide pathway and the renal circulationKlin Wochenschr1991696036091753683
  • LlinasMTGonzalezJDRodriguezFNavaETaddeiSSalazarFJRenal changes induced by nitric oxide and prostaglandin synthesis reduction: effects of trandolapril and verapamilHypertension19983126576649461237
  • ZouAPWuFCowleyAWJrProtective effect of angiotensin II-induced increase in nitric oxide in the renal medullary circulationHypertension199831Pt 22712769453315
  • StecDEMattsonDLRomanRJInhibition of renal outer medullary 20-HETE production produces hypertension in Lewis ratsHypertension199729Pt 23153199039121
  • CampeseVMNeurogenic factors and hypertension in renal diseaseKidney Int200057Suppl 75S2S6
  • AsahiKIchimoriKNakazawaHNitric oxide inhibits the formation of advanced glycation end productsKidney Int2000581780178711012913
  • KlahrSMorrisseyJJThe role of vasoactive compounds, growth factors and cytokines in the progression of renal diseaseKidney Int200057Suppl 75S7S14
  • LeeheyDJSinghAKAlaviNSinghRRole of angiotensin II in diabetic nephropathyKidney Int200058Suppl 77S93S98
  • TharauxPLChatziantoniouCCasellasDFouassierLArdaillouRDussauleJCVascular endothelin-1 gene expression and synthesis and effect on renal type I collagen synthesis and nephroangiosclerosis during nitric oxide synthase inhibition in ratsCirculation1999992185219110217661
  • SzilvassyZCsontTPaliTDroy-LefaixMTFerdinandyPNitric oxide, peroxynitrite and cGMP in atherosclerosis-induced hypertension in rabbits: beneficial effects of cicletanineJ Vasc Res200138394611173993
  • ThuraisinghamRCNottCADoddSMYaqoobMMIncreased nitrotyrosine staining in kidneys from patients with diabetic nephropathyKidney Int2000571968197210792615
  • WalkerLMWalkerPDImamSZAliSFMayeuxPREvidence for peroxynitrite formation in renal ischemia-reperfusion injury: studies with the inducible nitric oxide synthase inhibitor L-N(6)-(1-Iminoethyl) lysineJ Pharmacol Exp Ther200029541742210992009
  • BalcellsEMengQCJohnsonWHJrOparilSDell’ItaliaLJAngiotensin II formation from ACE and chymase in human and animal hearts: methods and species considerationsAm J Physiol19972734 Pt 2H1769H17749362242
  • PetrieMCPadmanabhanNMcDonaldJEHillierCConnellJMMcMurrayJJAngiotensin converting enzyme (ACE) and non-ACE dependent angiotensin II generation in resistance arteries from patients with heart failure and coronary heart diseaseJ Am Coll Cardiol2001371056106111263608
  • GriendlingKKSorescuDUshio-FukaiMNAD(P)H oxidase: role in cardiovascular biology and diseaseCirc Res20008649450110720409
  • HaugenENCroattAJNathKAAngiotensin II induces renal oxidant stress in vivo and heme oxygenase-1 in vivo and in vitroKidney Int20005814415210886559
  • HatakeyamaHMiyamoriLFujitaTTakedaYTakedaRYamamotoHVascular aldosterone: biosynthesis and a link to angiotensin II-induced hypertrophy of vascular smooth muscle cellsJ Biol Chem199428924316243207929089
  • SilvestreJSRobertVHeymesCMyocardial production of aldosterone and corticosterone in the rat. Physiological regulationJ Biol Chem1998273488348919478930
  • UllianMESchellingJRLinasSAldosterone enhances angiotensin II receptor binding and inositol phosphate responsesHypertension19922067731618554
  • KornelLSmoszna-KonaszewskaBAldosterone (ALDO) increases trans-membrane influx of Na+ in vascular smooth muscle (VSM) cells through increased synthesis of Na+ channelsSteroids1995601141197792795
  • WeberMAPurdyRECatecholamine mediated constrictor effects of aldosterone on vascular smooth muscleLife Sci198230200920177109834
  • IkedaUKanbeTNakayamaIKawaharaYYokoyamaMShimadaKAldosterone inhibits nitric oxide synthesis in vascular smooth muscle cells induced by interleukin-1bEur J Pharmacol199529069738575535
  • BrownNJNakamuraSMaLAldosterone modulates plasminogen activator inhibitor-1 and glomerulosclerosis in vivoKidney Int2000581219122710972684
  • EpsteinMAldosterone as a mediator of progressive renal disease: pathogenetic and clinical implicationsAm J Kidney Dis200137467768811273866
  • American Diabetes AssociationStandards of medical care for patients with diabetes mellitusDiabetes Care200124Suppl 1S33S66
  • BakrisGLWilliamsMDworkinLPreserving renal function in adults with hypertension and diabetes: a consensus approach. National Kidney Foundation Hypertension and Diabetes Executive Committees Working GroupAm J Kidney Dis200036364666110977801
  • RamsayLWilliamsBJohnstonGGuidelines for management of hypertension: report of the third working party of the British Hypertension SocietyJ Hum Hypertens199913956959210482967
  • FeldmanRDCampbellNLarochelleP1999Canadian recommendations for the management of hypertension. Task force for the development of the 1999 Canadian recommendations for the management of hypertensionCMAJ1999161Suppl 12S1S1710624417
  • ChalmersJMacMahonSManciaG1999 World Health Organization-International Society of Hypertension Guidelines for the management of hypertension. Guidelines sub-committee of the World Health OrganizationClin Exp Hypertens1999215–61009106010423121
  • JNC-VIThe sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressureArch Intern Med199715721241324469385294
  • LazarusJMBourgoignieJJBuckalewVMAchievement and safety of a low blood pressure goal in chronic renal disease. The modification of diet in Renal Disease Study GroupHypertension19972926416509040451
  • EstacioROJefersBWHiattWRBiggerstaffSLGiffordNSchrierRWThe effect of nisoldipine as compared with enalapril on cardiovascular outcomes in patients with non-insulin-dependent diabetes and hypertensionN Engl J Med1998338106456529486993
  • UK Prospective Diabetes Study GroupTight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38 UK Prospective Diabetes Study GroupBMJ199831771607037139732337
  • HanssonLZanchettiACarruthersSGEffects of intensive blood pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomized trial. HOT Study GroupLancet19983519118175517629635947
  • KauszATObradorGTPereiraBJAnemia management in patients with chronic renal insufficiencyAm J Kidney Dis2000366 Suppl 3S39S5111118157
  • LevinAThompsonCREthierJLeft ventricular mass index increase in early renal disease: impact of decline in hemoglobinAm J Kidney Dis199934112513410401026
  • BlockGAHulbert-ShearonTELevinNWPortFKAssociation of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: a national studyAm J Kidney Dis19983146076179531176
  • RossingPHommelESmidtUMParvingHHReduction in albuminuria predicts a beneficial effect on diminishing the progression of human diabetic nephropathy during antihypertensive treatmentDiabetologia19943755115168056190
  • GansevoortRTde ZeeuwDde JongPELong-term benefits of the antiproteinuric effect of angiotensin-converting enzyme inhibition in nondiabetic renal diseaseAm J Kidney Dis19932212022068322784
  • RussoDPisaniABallettaMMAdditive antiproteinuric effect of converting enzyme inhibitor and losartan in normotensive patients with IgA nephropathyAm J Kidney Dis19993385185610213639
  • CrepaldiGCartaQDeferrariGEffects of lisinopril and nifedipine on the progression to overt albuminuria in IDDM patients with incipient nephropathy and normal blood pressure. The Italian Microalbuminuria Study Group in IDDMDiabetes Care19982111041109538979
  • RuggenentiPPernaAGherardiGRenoprotective properties of ACE-inhibition in non-diabetic nephropathies with non-nephrotic proteinuriaLancet1999354917635936410437863
  • Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICROHOPE substudy. Heart Outcomes Prevention Evaluation Study InvestigatorsLancet200035525325910675071
  • LewisEJHunsickerLGClarkeWRfor the Collaborative Study GroupRenoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetesN Engl J Med200134585186011565517
  • BrennerBMCooperMEde ZeeuwDfor the RENAAL Study InvestigatorsEffects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathyN Engl J Med200134586186911565518
  • MacKinnonMShurrawSAkbariAKnollGAJaffeyJClarkHDCombination therapy with an angiotensin receptor blocker and an ACE inhibitor in proteinuric renal disease: a systematic review of the efficacy and safety dataAm J Kidney Dis20064882016797382
  • KunzRFriedrichCWolbersMMannJFMeta-analysis: effect of monotherapy and combination therapy with inhibitors of the renin angiotensin system on proteinuria in renal diseaseAnn Intern Med2008148304817984482
  • MannJFSchmiederREMcQueenMRenal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trialLancet200837254755318707986
  • BakrisGLSlataperRVicknairNSadlerRACE inhibitor mediated reductions in renal size and microalbuminuria in normotensive, diabetic subjectsJ Diabetes Complications199481268167383
  • EpsteinBJSmithSMChoksiRRecent changes in the landscape of combination RAS blockadeExpert Rev Cardiovasc Ther200971373138419900020
  • BrunnerHRLaraghJHBaerLEssential hypertension: renin and aldosterone, heart attack and strokeN Engl J Med19722864414484257928
  • ParikhNIGonaPLarsonMGWangTJPlasma renin activity and risk of cardiovascular disease and mortality: the Framingham Heart StudyEur Heart J2007282644265217895253
  • LorigaGVidiliGRuggenentiPRenal hemodynamics and renoprotectionNephron Clin Pract2008110c213c21918974652
  • NussbergerJGradmanAHSchmiederREPlasma renin and the antihypertensive effect of the orally active renin inhibitor aliskiren in clinical hypertensionInt J Clin Pract200761146117590217
  • BrownMJAliskirenCirculation200811877378418695203
  • BaldonciniRDesideriGBelliniCHigh plasma renin activity is combined with elevated urinary albumin excretion in essential hypertensive patientsKidney Int1999561499150410504501
  • YeyatiNLAdroguéHJInappropriately high plasma renin activity accompanies chronic loss of renal functionAm J Nephrol1996164714778955757
  • MalmqvistKOhmanKPLindLRelationships between left ventricular mass and the renin-angiotensin system, catecholamines, insulin and leptinJ Intern Med200225243043912528761
  • LicataGScaglioneRCorraoSHeredity and obesity-associated hypertension: impact of hormonal characteristics and left ventricular massJ Hypertens1995136116187594417
  • WeirMRBushCAndersonDRAntihypertensive efficacy, safety, and tolerability of the oral direct renin inhibitor aliskiren in patients with hypertension: a pooled analysisJASH20071426427720409858
  • BirkenhagerWHStaessenJADual inhibition of the renin system by aliskiren and valsartanLancet200737019519617658374
  • TaylorAAAndersonDRAroraVRenin system suppression with the oral direct renin inhibitor, aliskiren administered alone or in combinationJ Am Soc Nephrol200415312631333415579516
  • OhB-HMitchellJHerronJRChungJKhanMKeefeDLAliskiren, an oral renin inhibitor, provides dose-dependent efficacy and sustained 24-hour blood pressure control in patients with hypertensionJ Am Coll Cardiol200749111157116317367658
  • SchmiederREPhilippTGuerediagaJLong-term antihypertensive efficacy and safety of the oral direct renin inhibitor aliskiren: a 12-month randomized, double-blind comparator trial with hydrochlorothiazideCirculation2009119341742519139391
  • OparilSYarowsSPatelSFangHZhangJSatlinAEfficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: a randomised, double-blind trialLancet2007370958322122917658393
  • GradmanAHSchmiederRELinsRLNussbergerJChiangYBedigianMPAliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patientsCirculation20051111012101815723979
  • FramptonJECurranMPAliskiren: a review of its use in the management of hypertensionDrugs200767121767179217683174
  • UresinYTaylorAAKiloCEfficacy and safety of the direct renin inhibitor aliskiren and ramipril alone or in combination in patients with diabetes and hypertensionJ Renin Angiotensin Aldosterone Syst20078419020018205098
  • StrasserRHPuigJGFarsangCCroketMLiJvan IngenHA comparison of the tolerability of the direct renin inhibitor aliskiren and lisinopril in patients with severe hypertensionJ Hum Hypertens20072178078717541390
  • DrummondWMungerMARafiqueMAntihypertensive efficacy of the oral direct renin inhibitor Aliskiren as add-on therapy in patients not responding to amlodipine monotherapyJ Clin Hypertens2007910742750
  • VillamilAChrysantSGCalhounDRenin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazideJ Hypertens20072521722617143194
  • PoolJLSchmiederREAziziMAliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combination with valsartanAm J Hypertens200720112017198906
  • O’BrienEBartonJNussbergerJAliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or an angiotensin receptor blockerHypertension20074927628417159081
  • AndersenKWeinbergerMHConstanceCMComparative effects of aliskiren-based and ramipril-based therapy on the renin system during long-term (6 months) treatment and withdrawal in patients with hypertensionJ Renin Angiotensin Aldosterone Syst20091015716719617271
  • MungerMADrummondWEssopMRAliskiren as add-on to amlodipine provides significant additional blood pressure lowering without increased edema associated with doubling the amlodipine dose [abstract]Eur Heart J200627Suppl11716267068
  • ParvingHHPerssonFLewisJBLewisEJHollenbergNKAVOID Study InvestigatorsAliskiren combined with losartan in type 2 diabetes and nephropathyN Engl J Med20083582433244618525041
  • ParvingHHBrennerBMMcMurrayJJAliskiren trial in type 2 diabetes using cardio-renal endpoints (ALTITUDE): rationale and study designNephrol Dial Transplant2009241663167119145003