Exploring bacterial outer membrane barrier to combat bad bugs

References

• KostyanevTBontenMJO’BrienSThe Innovative Medicines Initiative’s New Drugs for Bad Bugs programme: European public-private partnerships for the development of new strategies to tackle antibiotic resistanceJ Antimicrob Chemother201671229029526568581
   PubMed Web of Science ®Google Scholar
• VentolaCLThe antibiotic resistance crisis: part 1: causes and threatsP T201540427728325859123
   PubMedGoogle Scholar
• GootzTDThe global problem of antibiotic resistanceCrit Rev Immunol2010301799320370622
   PubMed Web of Science ®Google Scholar
• StavengerRAWinterhalterMTRANSLOCATION project: how to get good drugs into bad bugsSci Transl Med20146228228ed7
   Web of Science ®Google Scholar
• NikaidoHRole of permeability barriers in resistance to beta-lactam antibioticsPharmacol Ther19852721972312412244
   PubMed Web of Science ®Google Scholar
• NikaidoHMolecular basis of bacterial outer membrane permeability revisitedMicrobiol Mol Biol Rev200367459365614665678
   PubMed Web of Science ®Google Scholar
• WinterhalterMCeccarelliMPhysical methods to quantify small antibiotic molecules uptake into Gram-negative bacteriaEur J Pharm Biopharm201595Pt A636726036449
   PubMed Web of Science ®Google Scholar
• ChattopadhyayMKJaganandhamMVVesicles-mediated resistance to antibiotics in bacteriaFront Microbiol2015675826257725
   PubMed Web of Science ®Google Scholar
• KulkarniHMJagannadhamMVBiogenesis and multifaceted roles of outer membrane vesicles from Gram-negative bacteriaMicrobiology2014160102109212125069453
   PubMed Web of Science ®Google Scholar
• ChattopadhyayMKJagannadhamMVCorrigendum: vesicles-mediated resistance to antibiotics in bacteriaFront Microbiol2015675826257725
   PubMed Web of Science ®Google Scholar
• McBroomAJKuehnMJRelease of outer membrane vesicles by Gram-negative bacteria is a novel envelope stress responseMol Microbiol200763254555817163978
   PubMed Web of Science ®Google Scholar
• MarediaRDevineniNLentzPVesiculation from Pseudomonas aeruginosa under SOSScientific World J2012201218
   Web of Science ®Google Scholar
• KulkarniHMSwamyChVJagannadhamMVMolecular characterization and functional analysis of outer membrane vesicles from the antarctic bacterium Pseudomonas syringae suggest a possible response to environmental conditionsJ Proteome Res20141331345135824437924
   PubMed Web of Science ®Google Scholar
• SchwechheimerCKuehnMJOuter-membrane vesicles from Gram-negative bacteria: biogenesis and functionsNat Rev Microbiol2015131060561926373371
   PubMed Web of Science ®Google Scholar
• BenzRStructure and function of porins from gram-negative bacteriaAnnu Rev Microbiol1988423593932849372
   PubMed Web of Science ®Google Scholar
• JamesCEMahendranKRMolitorAHow beta-lactam antibiotics enter bacteria: a dialogue with the porinsPLoS One200945e545319434239
   PubMed Web of Science ®Google Scholar
• SchirmerTGeneral and specific porins from bacterial outer membranesJ Struct Biol199812121011099615433
   PubMed Web of Science ®Google Scholar
• SchulzGEThe structure of bacterial outer membrane proteinsBiochim Biophys Acta20021565230831712409203
   PubMed Web of Science ®Google Scholar
• ScorciapinoMAD’AgostinoTAcosta-GutierrezSMallociGBodrenkoICeccarelliMExploiting the porin pathway for polar compound delivery into Gram-negative bacteriaFuture Med Chem20168101047106227303954
   PubMed Web of Science ®Google Scholar
• SinghHThangarajPChakrabartiAAcinetobacter baumannii: a brief account of mechanisms of multidrug resistance and current and future therapeutic managementJ Clin Diagn Res20137112602260524392418
   PubMedGoogle Scholar
• ZiervogelBKRouxBThe binding of antibiotics in OmpF porinStructure2013211768723201272
   PubMed Web of Science ®Google Scholar
• PagesJMJamesCEWinterhalterMThe porin and the permeating antibiotic: a selective diffusion barrier in Gram-negative bacteriaNat Rev Microbiol200861289390318997824
   PubMed Web of Science ®Google Scholar
• DupontHChoinierPRocheDStructural alteration of OmpR as a source of ertapenem resistance in a CTX-M-15-producing Escherichia coli O25b:H4-ST131 clinical isolateAntimicrob Agents Chemother2017615e00014e0001728264855
   PubMed Web of Science ®Google Scholar
• ChakradharSBreaking through: How researchers are gaining entry into barricaded bacteriaNat Med201723890791028777786
   PubMed Web of Science ®Google Scholar
• NakaeTOuter membrane of Salmonella. Isolation of protein complex that produces transmembrane channelsJ Biol Chem1976251721762178773934
   PubMed Web of Science ®Google Scholar
• NikaidoHVaaraMMolecular basis of bacterial outer membrane permeabilityMicrobiol Rev19854911322580220
   PubMedGoogle Scholar
• Nguyen-DistecheMPollockJJGhuysenJMSensitivity to ampicillin and cephalothin of enzymes involved in wall peptide crosslinking in Escherichia coli K12, strain 44Eur J Biochem19744134574634593965
   PubMedGoogle Scholar
• SchulzGEPorins: general to specific, native to engineered passive poresCurr Opin Struct Biol1996644854908794162
   PubMed Web of Science ®Google Scholar
• GuillierMGottesmanSStorzGModulating the outer membrane with small RNAsGenes Dev200620172338234816951250
   PubMed Web of Science ®Google Scholar
• FahieMAYangBMullisMHoldenMAChenMSelective detection of protein homologues in serum using an OmpG nanoporeAnal Chem20158721111431114926451707
   PubMed Web of Science ®Google Scholar
• LiHLuoYFWilliamsBJBlackwellTSXieCMStructure and function of OprD protein in Pseudomonas aeruginosa: from antibiotic resistance to novel therapiesInt J Med Microbiol20123022636822226846
   PubMed Web of Science ®Google Scholar
• DupontHGaillotOGoetgheluckASMolecular characterization of carbapenem-nonsusceptible enterobacterial isolates collected during a prospective interregional survey in France and susceptibility to the novel ceftazidime-avibactam and aztreonam-avibactam combinationsAntimicrob Agents Chemother201560121522126482307
   PubMed Web of Science ®Google Scholar
• HancockREWoodruffWARoles of porin and beta-lactamase in beta-lactam resistance of Pseudomonas aeruginosaRev Infect Dis19881047707752460909
   PubMedGoogle Scholar
• IredellJBrownJTaggKAntibiotic resistance in Enterobacteriaceae: mechanisms and clinical implicationsBMJ2016352h642026858245
   PubMed Web of Science ®Google Scholar
• ZahnMBhamidimarri SatyaPBasléAWinterhalterMvan den BergBStructural insights into outer membrane permeability of Acinetobacter baumanniiStructure201624222123126805524
   PubMed Web of Science ®Google Scholar
• GhaiIPiraAScorciapinoMAGeneral method to determine the flux of charged molecules through nanopores applied to beta-lactamase inhibitors and OmpFJ Phys Chem Lett2017861295130128240914
   PubMed Web of Science ®Google Scholar
• KretschmerNDamianakosHChinouIComparison of the cytotoxicity and antimicrobial activity of several isohexenylnaphthazarinsPlanta Med20117712M199
   Web of Science ®Google Scholar
• HancockREBrinkmanFSFunction of pseudomonas porins in uptake and effluxAnnu Rev Microbiol200256173812142471
   PubMed Web of Science ®Google Scholar
• Fito-BoncompteLChapalainABouffartiguesEFull virulence of Pseudomonas aeruginosa requires OprFInfect Immun20117931176118621189321
   PubMed Web of Science ®Google Scholar
• NestorovichEMSugawaraENikaidoHBezrukovSMPseudomonas aeruginosa porin OprF: properties of the channelJ Biol Chem200628124162301623716617058
   PubMed Web of Science ®Google Scholar
• SugawaraENestorovichEMBezrukovSMNikaidoHPseudomonas aeruginosa porin OprF exists in two different conformationsJ Biol Chem200628124162201622916595653
   PubMed Web of Science ®Google Scholar
• PagesJMPeslierSKeatingTALavigneJPNicholsWWRole of the outer membrane and porins in susceptibility of beta-lactamase-producing Enterobacteriaceae to ceftazidime-avibactamAntimicrob Agents Chemother20156031349135926666933
   PubMed Web of Science ®Google Scholar
• Acosta GutierrezSBodrenkoIScorciapinoMACeccarelliMMacroscopic electric field inside water-filled biological nanoporesPhys Chem Chem Phys201618138855886426931352
   PubMed Web of Science ®Google Scholar
• LovelleMMachTMahendranKRWeingartHWinterhalterMGameiroPInteraction of cephalosporins with outer membrane channels of Escherichia coli. Revealing binding by fluorescence quenching and ion conductance fluctuationsPhys Chem Chem Phys20111341521153021152583
   PubMed Web of Science ®Google Scholar
• MahendranKRKreirMWeingartHFertigNWinterhalterMPermeation of antibiotics through Escherichia coli OmpF and OmpC porins: screening for influx on a single-molecule levelJ Biomol Screen201015330230720086208
   PubMedGoogle Scholar
• PinetEFranceschiCDavin-RegliAZambardiGPagesJMRole of the culture medium in porin expression and piperacillin-tazobactam susceptibility in Escherichia coliJ Med Microbiol201564111305131426242994
   PubMed Web of Science ®Google Scholar
• LiuNSamartzidouHLeeKWBriggsJMDelcourAHEffects of pore mutations and permeant ion concentration on the spontaneous gating activity of OmpC porinProtein Eng200013749150010906344
   PubMedGoogle Scholar
• LouHChenMBlackSSAltered antibiotic transport in OmpC mutants isolated from a series of clinical strains of multi-drug resistant E. coliPLoS One2011610e2582522053181
   PubMed Web of Science ®Google Scholar
• SugawaraEKojimaSNikaidoHKlebsiella pneumoniae major porins OmpK35 and OmpK36 allow more efficient diffusion of beta-lactams than their Escherichia coli homologs OmpF and OmpCJ Bacteriol2016198233200320827645385
   PubMed Web of Science ®Google Scholar
• Aguilella-ArzoMGarcia-CelmaJJCerveraJAlcarazAAguilellaVMElectrostatic properties and macroscopic electrodiffusion in OmpF porin and mutantsBioelectrochemistry200770232032716769257
   PubMed Web of Science ®Google Scholar
• ApetreiAAsandeiAParkYHahmKSWinterhalterMLuchianTUnimolecular study of the interaction between the outer membrane protein OmpF from E. coli and an analogue of the HP(2–20) antimicrobial peptideJ Bioenerg Biomembr201042217318020180000
   PubMed Web of Science ®Google Scholar
• BajajHScorciapinoMAMoynieLMolecular basis of filtering carbapenems by porins from beta-lactam-resistant clinical strains of Escherichia coliJ Biol Chem201629162837284726645688
   PubMed Web of Science ®Google Scholar
• BodrenkoIBajajHRuggeronePWinterhalterMCeccarelliMAnalysis of fast channel blockage: revealing substrate binding in the microsecond rangeAnalyst2015140144820482725717496
   PubMed Web of Science ®Google Scholar
• BrauserASchroederIGutsmannTModulation of enrofloxacin binding in OmpF by Mg2+ as revealed by the analysis of fast flickering single-porin currentJ Gen Physiol20121401698222689827
   PubMed Web of Science ®Google Scholar
• BredinJSaintNMalleaMAlteration of pore properties of Escherichia coli OmpF induced by mutation of key residues in anti-loop 3 regionBiochem J2002363Pt 352152811964152
   PubMed Web of Science ®Google Scholar
• CamaJBajajHPagliaraSQuantification of fluoroquinolone uptake through the outer membrane channel OmpF of Escherichia coliJ Am Chem Soc201513743138361384326478537
   PubMed Web of Science ®Google Scholar
• DanelonCNestorovichEMWinterhalterMCeccarelliMBezrukovSMInteraction of zwitterionic penicillins with the OmpF channel facilitates their translocationBiophys J20069051617162716339889
   PubMed Web of Science ®Google Scholar
• DanelonCSuenagaAWinterhalterMYamatoIMolecular origin of the cation selectivity in OmpF porin: single channel conductances vs. free energy calculationBiophys Chem2003104359160312914905
   PubMed Web of Science ®Google Scholar
• GhaiIWinterhalterMWagnerRProbing transport of charged beta-lactamase inhibitors through OmpC, a membrane channel from E. coliBiochem Biophys Res Commun20174841515528109883
   PubMed Web of Science ®Google Scholar
• HajjarEBessonovAMolitorAToward screening for antibiotics with enhanced permeation properties through bacterial porinsBiochemistry201049326928693520604536
   PubMed Web of Science ®Google Scholar
• HajjarEMahendranKRKumarABridging timescales and length scales: from macroscopic flux to the molecular mechanism of antibiotic diffusion through porinsBiophys J201098456957520159153
   PubMed Web of Science ®Google Scholar
• ImWRouxBIon permeation and selectivity of OmpF porin: a theoretical study based on molecular dynamics, Brownian dynamics, and continuum electrodiffusion theoryJ Mol Biol2002322485186912270719
   PubMed Web of Science ®Google Scholar
• KumarAHajjarERuggeronePCeccarelliMMolecular simulations reveal the mechanism and the determinants for ampicillin translocation through OmpFJ Phys Chem B2010114299608961620590090
   PubMed Web of Science ®Google Scholar
• LamichhaneUIslamTPrasadSWeingartHMahendranKRWinterhalterMPeptide translocation through the mesoscopic channel: binding kinetics at the single molecule levelEur Biophys J201342536336923271514
   PubMed Web of Science ®Google Scholar
• MachTNevesPSpigaEFacilitated permeation of antibiotics across membrane channels—interaction of the quinolone moxifloxacin with the OmpF channelJ Am Chem Soc200813040133011330918788798
   PubMed Web of Science ®Google Scholar
• MahendranKRHajjarEMachTMolecular basis of enrofloxacin translocation through OmpF, an outer membrane channel of Escherichia coli—when binding does not imply translocationJ Phys Chem B2010114155170517920349984
   PubMed Web of Science ®Google Scholar
• NestorovichEMDanelonCWinterhalterMBezrukovSMDesigned to penetrate: time-resolved interaction of single antibiotic molecules with bacterial poresProc Natl Acad Sci U S A200299159789979412119404
   PubMed Web of Science ®Google Scholar
• NevesPBerkaneEGameiroPWinterhalterMde CastroBInteraction between quinolones antibiotics and bacterial outer membrane porin OmpFBiophys Chem2005113212312815617818
   PubMed Web of Science ®Google Scholar
• NevesPSousaIWinterhalterMGameiroPFluorescence quenching as a tool to investigate quinolone antibiotic interactions with bacterial protein OmpFJ Membr Biol2009227313314019148694
   PubMed Web of Science ®Google Scholar
• PezeshkiSChimerelCBessonovANWinterhalterMKleinekathoferUUnderstanding ion conductance on a molecular level: an all-atom modeling of the bacterial porin OmpFBiophys J20099771898190619804720
   PubMed Web of Science ®Google Scholar
• PhalePSPhilippsenAWidmerCPhaleVPRosenbuschJPSchirmerTRole of charged residues at the OmpF porin channel constriction probed by mutagenesis and simulationBiochemistry200140216319632511371193
   PubMed Web of Science ®Google Scholar
• SinghPRCeccarelliMLovelleMWinterhalterMMahendranKRAntibiotic permeation across the OmpF channel: modulation of the affinity site in the presence of magnesiumJ Phys Chem B2012116154433443822369436
   PubMed Web of Science ®Google Scholar
• VidalSBredinJPagesJMBarbeJBeta-lactam screening by specific residues of the OmpF eyeletJ Med Chem20054851395140015743183
   PubMed Web of Science ®Google Scholar
• WeichbrodtCBajajHBaakenGAntibiotic translocation through porins studied in planar lipid bilayers using parallel platformsAnalyst2015140144874488125834843
   PubMed Web of Science ®Google Scholar
• BenzRDarveauRPHancockREOuter-membrane protein PhoE from Escherichia coli forms anion-selective pores in lipid-bilayer membranesEur J Biochem198414023193246325185
   PubMedGoogle Scholar
• DarveauRPHancockREBenzRChemical modification of the anion selectivity of the PhoE porin from the Escherichia coli outer membraneBiochim Biophys Acta1984774167746329296
   PubMed Web of Science ®Google Scholar
• BornetCDavin-RegliABosiCPagesJMBolletCImipenem resistance of Enterobacter aerogenes mediated by outer membrane permeabilityJ Clin Microbiol20003831048105210698994
   PubMed Web of Science ®Google Scholar
• LavigneJPSottoANicolas-ChanoineMHBouzigesNPagesJMDavin-RegliAAn adaptive response of Enterobacter aerogenes to imipenem: regulation of porin balance in clinical isolatesInt J Antimicrob Agents201341213013623280442
   PubMed Web of Science ®Google Scholar
• ThiolasABornetCDavin-RegliAPagesJMBolletCResistance to imipenem, cefepime, and cefpirome associated with mutation in Omp36 osmoporin of Enterobacter aerogenesBiochem Biophys Res Commun2004317385185615081418
   PubMed Web of Science ®Google Scholar
• BornetCSaintNFetnaciLOmp35, a new Enterobacter aerogenes porin involved in selective susceptibility to cephalosporinsAntimicrob Agents Chemother20044862153215815155215
   PubMed Web of Science ®Google Scholar
• ArunmaneeWPathaniaMSolovyovaASGram-negative trimeric porins have specific LPS binding sites that are essential for porin biogenesisProc Natl Acad Sci U S A201611334E5034E504327493217
   PubMed Web of Science ®Google Scholar
• CastanheiraMMendesRESaderHSLow frequency of ceftazidime-avibactam resistance among Enterobacteriaceae isolates carrying blaKPC collected in U.S. hospitals rom 2012 to 2015Antimicrob Agents Chemother2017613
   Web of Science ®Google Scholar
• ErenEParkinJAdelanwaAToward understanding the outer membrane uptake of small molecules by Pseudomonas aeruginosaJ Biol Chem201328817120421205323467408
   PubMed Web of Science ®Google Scholar
• LiuJWolfeAJErenECation selectivity is a conserved feature in the OccD subfamily of Pseudomonas aeruginosaBiochim Biophys Acta20121818112908291622824298
   PubMed Web of Science ®Google Scholar
• BiswasSMohammadMMPatelDRMovileanuLvan den BergBStructural insight into OprD substrate specificityNat Struct Mol Biol200714111108110917952093
   PubMed Web of Science ®Google Scholar
• HuangHHancockREThe role of specific surface loop regions in determining the function of the imipenem-specific pore protein OprD of Pseudomonas aeruginosaJ Bacteriol199617811308530908655484
   PubMed Web of Science ®Google Scholar
• SamantaSScorciapinoMACeccarelliMMolecular basis of substrate translocation through the outer membrane channel OprD of Pseudomonas aeruginosaPhys Chem Chem Phys20151737238672387626306922
   PubMed Web of Science ®Google Scholar
• ErenEVijayaraghavanJLiuJSubstrate specificity within a family of outer membrane carboxylate channelsPLoS Biol2012101e100124222272184
   PubMed Web of Science ®Google Scholar
• LiuJErenEVijayaraghavanJOccK channels from Pseudomonas aeruginosa exhibit diverse single-channel electrical signatures but conserved anion selectivityBiochemistry201251112319233022369314
   PubMed Web of Science ®Google Scholar
• ModiNBenzRHancockREKleinekathoferUModeling the ion selectivity of the phosphate specific channel OprPJ Phys Chem Lett20123233639364526290999
   PubMed Web of Science ®Google Scholar
• SoundararajanGBhamidimarriSPWinterhalterMUnderstanding carbapenem translocation through OccD3 (OpdP) of Pseudomonas aeruginosaACS Chem Biol20171261656166428440622
   PubMed Web of Science ®Google Scholar
• ChalhoubHPletzerDWeingartHMechanisms of intrinsic resistance and acquired susceptibility of Pseudomonas aeruginosa isolated from cystic fibrosis patients to temocillin, a revived antibioticSci Rep201774020828091521
   PubMed Web of Science ®Google Scholar
• ChenekeBRIndicMvan den BergBMovileanuLAn outer membrane protein undergoes enthalpy- and entropy-driven transitionsBiochemistry201251265348535822680931
   PubMed Web of Science ®Google Scholar
• ChenekeBRvan den BergBMovileanuLAnalysis of gating transitions among the three major open states of the OpdK channelBiochemistry201150224987499721548584
   PubMed Web of Science ®Google Scholar
• PothulaKRDhanasekarNNLamichhaneUSingle residue acts as gate in OccK channelsJ Phys Chem B2017121122614262128257208
   PubMed Web of Science ®Google Scholar
• PothulaKRKleinekathoferUTheoretical analysis of ion conductance and gating transitions in the OpdK (OccK1) channelAnalyst2015140144855486425781224
   PubMed Web of Science ®Google Scholar
• SamantaSD’AgostinoTGhaiIHow to get large drugs through small pores? Exploiting the porins pathway in Pseudomonas aeruginosaBiophys J20171123 Suppl 1416a27955889
   PubMed Web of Science ®Google Scholar
• TamberSMaierEBenzRHancockRECharacterization of OpdH, a Pseudomonas aeruginosa porin involved in the uptake of tricarboxylatesJ Bacteriol2007189392993917114261
   PubMed Web of Science ®Google Scholar
• ModiNGangulySBarcena-UribarriIStructure, dynamics, and substrate specificity of the OprO porin from Pseudomonas aeruginosaBiophys J201510971429143826445443
   PubMed Web of Science ®Google Scholar
• ModiNBarcena-UribarriIBainsMBenzRHancockREKleinekathoferURole of the central arginine R133 toward the ion selectivity of the phosphate specific channel OprP: effects of charge and solvationBiochemistry201352335522553223875754
   PubMed Web of Science ®Google Scholar
• ModiNBarcena-UribarriIBainsMBenzRHancockREKleinekathoferUTuning the affinity of anion binding sites in porin channels with negatively charged residues: molecular details for OprPACS Chem Biol201510244145125333751
   PubMed Web of Science ®Google Scholar
• PongprayoonPBecksteinOWeeCLSansomMSSimulations of anion transport through OprP reveal the molecular basis for high affinity and selectivity for phosphateProc Natl Acad Sci U S A200910651216142161819966228
   PubMed Web of Science ®Google Scholar
• Catel-FerreiraMNehmeRMolleVDeciphering the function of the outer membrane protein OprD homologue of Acinetobacter baumanniiAntimicrob Agents Chemother20125673826383222564848
   PubMed Web of Science ®Google Scholar
• Catel-FerreiraMCoadouGMolleVStructure-function relationships of CarO, the carbapenem resistance-associated outer membrane protein of Acinetobacter baumanniiJ Antimicrob Chemother20116692053205621705362
   PubMed Web of Science ®Google Scholar
• ZahnMD’AgostinoTErenEBasleACeccarelliMvan den BergBSmall-molecule transport by CarO, an abundant eight-stranded beta-barrel outer membrane protein from Acinetobacter baumanniiJ Mol Biol2015427142329233925846137
   PubMed Web of Science ®Google Scholar
• IyerRDelcourAHComplex inhibition of OmpF and OmpC bacterial porins by polyaminesJ Biol Chem19972723018595186019228026
   PubMed Web of Science ®Google Scholar
• SaintNLouKLWidmerCLuckeyMSchirmerTRosenbuschJPStructural and functional characterization of OmpF porin mutants selected for larger pore size. II. Functional characterizationJ Biol Chem19962713420676206808702817
   PubMed Web of Science ®Google Scholar
• LouKLSaintNPrilipovAStructural and functional characterization of OmpF porin mutants selected for larger pore size. I. Crystallographic analysisJ Biol Chem19962713420669206758702816
   PubMed Web of Science ®Google Scholar
• PhalePSSchirmerTPrilipovALouK-LHardmeyerARosenbuschJPVoltage gating of Escherichia coli porin channels: role of the constriction loopProc Natl Acad Sci U S A19979413674167459192635
   PubMed Web of Science ®Google Scholar
• StockJBRauchBRosemanSPeriplasmic space in Salmonella typhimurium and Escherichia coliJ Biol Chem19772522178507861334768
   PubMed Web of Science ®Google Scholar
• TestaCAJohnsonLJA whole-cell phenotypic screening platform for identifying methylerythritol phosphate pathway-selective inhibitors as novel antibacterial agentsAntimicrob Agents Chemother20125694906491322777049
   PubMed Web of Science ®Google Scholar
• MortimerPGSPiddockLJVA comparison of methods used for measuring the accumulation of quinolones by enterobacteriaceae, Pseudomonas aeruginosa and Staphylococcus aureusJ Antimicrob Chemother19912856396531663928
   PubMed Web of Science ®Google Scholar
• GoessensWHvan der BijAKvan BoxtelRAntibiotic trapping by plasmid-encoded CMY-2 beta-lactamase combined with reduced outer membrane permeability as a mechanism of carbapenem resistance in Escherichia coliAntimicrob Agents Chemother20135783941394923733461
   PubMed Web of Science ®Google Scholar
• ShinJRLimKJKimDJChoJHKimSCDisplay of multimeric antimicrobial peptides on the Escherichia coli cell surface and its application as whole-cell antibioticsPLoS One201383e5899723516591
   PubMed Web of Science ®Google Scholar
• CroxenMALawRJScholzRKeeneyKMWlodarskaMFinlayBBRecent advances in understanding enteric pathogenic Escherichia coliClin Microbiol Rev201326482288024092857
   PubMed Web of Science ®Google Scholar
• FoxDTSchmidtENTianHSub-inhibitory fosmidomycin exposures elicits oxidative stress in Salmonella enterica serovar Typhimurium LT2PLoS One201494e9527124751777
   PubMed Web of Science ®Google Scholar
• DavisTDGerryCJTanDSGeneral platform for systematic quantitative evaluation of small-molecule permeability in bacteriaACS Chem Biol20149112535254425198656
   PubMed Web of Science ®Google Scholar
• ZhouYJoubranCMiller-VedamLThinking outside the “bug”: a unique assay to measure intracellular drug penetration in gram-negative bacteriaAnal Chem20158773579358425753586
   PubMed Web of Science ®Google Scholar
• BezrukovSMBerezhkovskiiAMSzaboADiffusion model of solute dynamics in a membrane channel: mapping onto the two-site model and optimizing the fluxJ Chem Phys20071271111510117887882
   PubMed Web of Science ®Google Scholar
• O’SheaRMoserHEPhysicochemical properties of antibacterial compounds: implications for drug discoveryJ Med Chem200851102871287818260614
   PubMed Web of Science ®Google Scholar
• ScorciapinoMAAcosta-GutierrezSBenkerrouDRationalizing the permeation of polar antibiotics into Gram-negative bacteriaJ Phys Condens Matter2017291111300128155846
   PubMed Web of Science ®Google Scholar
• KrasilnikovOVSabirovRZTernovskyVIMerzliakPGMuratkhodjaevJNA simple method for the determination of the pore radius of ion channels in planar lipid bilayer membranesFEMS Microbiol Immunol199251–3931001384601
   PubMedGoogle Scholar
• Barcena-UribarriITheinMMaierEBondeMBergstromSBenzRUse of nonelectrolytes reveals the channel size and oligomeric constitution of the Borrelia burgdorferi P66 porinPLoS One2013811e7827224223145
   PubMed Web of Science ®Google Scholar
• KrasilnikovOVDa CruzJBYuldashevaLNVarandaWANogueiraRAA novel approach to study the geometry of the water lumen of ion channels: colicin Ia channels in planar lipid bilayersJ Membr Biol1998161183929430623
   PubMed Web of Science ®Google Scholar
• KrasilnikovOVSizing channels with neutral polymersKasianowiczJJKellermayerMDeamerDWStructure and Dynamics of Confined PolymersDordrechtSpringer200297115
   Google Scholar
• BajajHAcosta GutierrezSBodrenkoIBacterial outer membrane porins as electrostatic nanosieves: exploring transport rules of small polar moleculesACS Nano20171165465547328485920
   PubMed Web of Science ®Google Scholar
• SchwarzGDanelonCWinterhalterMOn translocation through a membrane channel via an internal binding site: kinetics and voltage dependenceBiophys J20038452990299812719230
   PubMed Web of Science ®Google Scholar
• TranQTWilliamsSFaridRErdemliGPearlsteinRThe translocation kinetics of antibiotics through porin OmpC: insights from structure-based solvation mapping using WaterMapProteins201381229129923011778
   PubMed Web of Science ®Google Scholar
• FontanaJMAlexanderESalvatoreMTranslational research in infectious disease: current paradigms and challenges aheadTransl Res2012159643045322633095
   PubMed Web of Science ®Google Scholar
• GoldmanMThe innovative medicines initiative: a European response to the innovation challengeClin Pharmacol Ther201291341842522318619
   PubMed Web of Science ®Google Scholar