338
Views
22
CrossRef citations to date
0
Altmetric
Review

Diversity and evolution of drug resistance mechanisms in Mycobacterium tuberculosis

&
Pages 333-342 | Published online: 13 Oct 2017

References

  • World Health OrganizationGlobal tuberculosis report 2016GenevaWorld Health Organization2016 Available from: http://www.who.int/tb/publications/global_report/en/Accessed October 4, 2017
  • BritesDGagneuxSCo-evolution of Mycobacterium tuberculosis and Homo sapiensImmunol Rev2015264162425703549
  • GutierrezMCBrisseSBroschRAncient origin and gene mosaicism of the progenitor of Mycobacterium tuberculosisPLoS Pathog20051119
  • HershbergRLipatovMSmallPMHigh functional diversity in Mycobacterium tuberculosis driven by genetic drift and human demographyPLoS Biol20086120060311
  • ComasICoscollaMLuoTOut-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humansNat Genet201345101176118223995134
  • DeloguGSaliMFaddaGThe biology of Mycobacterium tuberculosis infectionMediterr J Hematol Infect Dis201351070
  • FonsecaJDKnightGMMcHughTDThe complex evolution of antibiotic resistance in Mycobacterium tuberculosisInt J Infect Dis2015329410025809763
  • CombsDLO’BrienRJGeiterLJUSPHS tuberculosis short-course chemotherapy trial 21: effectiveness, toxicity, and acceptability. The report of final resultsAnn Intern Med199011263974062155569
  • EspinalMAKimSJSuarezPGStandard short-course chemotherapy for drug-resistant tuberculosis: treatment outcomes in 6 countriesJAMA2000283192537254510815117
  • GuntherGMultidrug-resistant and extensively drug-resistant tuberculosis: a review of current concepts and future challengesClin Med2014143279285
  • CoscollaMGagneuxSConsequences of genomic diversity in Mycobacterium tuberculosisSemin Immunol201426643144425453224
  • CollFMcNerneyRGuerra-AssuncaoJAA robust SNP barcode for typing Mycobacterium tuberculosis complex strainsNat Commun20145481225176035
  • BorrellSGagneuxSInfectiousness, reproductive fitness and evolution of drug-resistant Mycobacterium tuberculosisInt J Tuberc Lung Dis200913121456146619919762
  • McGrathMGey van PittiusNCvan HeldenPDWarrenRMWarnerDFMutation rate and the emergence of drug resistance in Mycobacterium tuberculosisJ Antimicrob Chemother201469229230224072169
  • MerkerMKohlTARoetzerAWhole genome sequencing reveals complex evolution patterns of multidrug-resistant Mycobacterium tuberculosis Beijing strains in patientsPLoS One2013812e8255124324807
  • Dos VultosTMestreORauzierJEvolution and diversity of clonal bacteria: the paradigm of Mycobacterium tuberculosisPLoS One2008320001538
  • GagneuxSLongCDSmallPMVanTSchoolnikGKBohannanBJThe competitive cost of antibiotic resistance in Mycobacterium tuberculosisScience200631257821944194616809538
  • BillingtonOJMcHughTDGillespieSHPhysiological cost of rifampin resistance induced in vitro in Mycobacterium tuberculosisAntimicrob Agents Chemother19994381866186910428904
  • DaviesAPBillingtonOJBannisterBAWeirWRMcHughTDGillespieSHComparison of fitness of two isolates of Mycobacterium tuberculosis, one of which had developed multi-drug resistance during the course of treatmentJ Infect200041218418711023769
  • SanderPSpringerBPrammanananTFitness cost of chromosomal drug resistance-conferring mutationsAntimicrob Agents Chemother20024651204121111959546
  • BottgerECSpringerBPletschetteMSanderPFitness of antibiotic-resistant microorganisms and compensatory mutationsNat Med1998412134313449846553
  • AnderssonDIHughesDPersistence of antibiotic resistance in bacterial populationsFEMS Microbiol Rev201135590191121707669
  • SprattBGAntibiotic resistance: counting the costCurr Biol1996610121912218939559
  • OlofssonSKCarsOOptimizing drug exposure to minimize selection of antibiotic resistanceClin Infect Dis2007145S129S136
  • GagneuxSBurgosMVDeRiemerKImpact of bacterial genetics on the transmission of isoniazid-resistant Mycobacterium tuberculosisPLoS Pathog20062616
  • van DoornHRde HaasPEKremerKVandenbroucke-GraulsCMBorgdorffMWvan SoolingenDPublic health impact of isoniazid-resistant Mycobacterium tuberculosis strains with a mutation at amino-acid position 315 of katG: a decade of experience in The NetherlandsClin Microbiol Infect200612876977516842572
  • AnderssonDIHughesDAntibiotic resistance and its cost: is it possible to reverse resistance?Nat Rev Microbiol20108426027120208551
  • AnderssonDILevinBRThe biological cost of antibiotic resistanceCurr Opin Microbiol19992548949310508723
  • ShermanDRMdluliKHickeyMJCompensatory ahpC gene expression in isoniazid-resistant Mycobacterium tuberculosisScience19962725268164116438658136
  • RamaswamySMusserJMMolecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 updateTuber Lung Dis199879132910645439
  • SomoskoviAParsonsLMSalfingerMThe molecular basis of resistance to isoniazid, rifampin, and pyrazinamide in Mycobacterium tuberculosisRespir Res20012316416811686881
  • MariamDHMengistuYHoffnerSEAnderssonDIEffect of rpoB mutations conferring rifampin resistance on fitness of Mycobacterium tuberculosisAntimicrob Agents Chemother20044841289129415047531
  • ComasIBorrellSRoetzerAWhole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genesNat Genet201144110611022179134
  • YangCLuoTShenXTransmission of multidrug-resistant Mycobacterium tuberculosis in Shanghai, China: a retrospective observational study using whole-genome sequencing and epidemiological investigationLancet Infect Dis201717327528427919643
  • de VosMMullerBBorrellSPutative compensatory mutations in the rpoC gene of rifampin-resistant Mycobacterium tuberculosis are associated with ongoing transmissionAntimicrob Agents Chemother201357282783223208709
  • BrandisGPietschFAlemayehuRHughesDComprehensive phenotypic characterization of rifampicin resistance mutations in Salmonella provides insight into the evolution of resistance in Mycobacterium tuberculosisJ Antimicrob Chemother201570368068525362573
  • MeftahiNNamouchiAMhenniBBrandisGHughesDMardassiHEvidence for the critical role of a secondary site rpoB mutation in the compensatory evolution and successful transmission of an MDR tuberculosis outbreak strainJ Antimicrob Chemother201671232433226538504
  • FreihoferPAkbergenovRTeoYJuskevicieneRAnderssonDIBottgerECNonmutational compensation of the fitness cost of antibiotic resistance in mycobacteria by overexpression of tlyA rRNA methylaseRNA201622121836184327698071
  • PhillipsPCEpistasis–the essential role of gene interactions in the structure and evolution of genetic systemsNat Rev Genet200891185586718852697
  • WongAEpistasis and the evolution of antimicrobial resistanceFront Microbiol2017824628261193
  • BorrellSTeoYGiardinaFEpistasis between antibiotic resistance mutations drives the evolution of extensively drug-resistant tuberculosisEvol Med Public Health201316574
  • TrindadeSSousaAXavierKBDionisioFFerreiraMGGordoIPositive epistasis drives the acquisition of multidrug resistancePLoS Genet20095724
  • BorrellSGagneuxSStrain diversity, epistasis and the evolution of drug resistance in Mycobacterium tuberculosisClin Microbiol Infect201117681582021682802
  • SchragSJPerrotVLevinBRAdaptation to the fitness costs of antibiotic resistance in Escherichia coliProc Biol Sci19972641386128712919332013
  • MullerBBorrellSRoseGGagneuxSThe heterogeneous evolution of multidrug-resistant Mycobacterium tuberculosisTrends Genet201329316016923245857
  • FennerLEggerMBodmerTEffect of mutation and genetic background on drug resistance in Mycobacterium tuberculosisAntimicrob Agents Chemother20125663047305322470121
  • SunGLuoTYangCDynamic population changes in Mycobacterium tuberculosis during acquisition and fixation of drug resistance in patientsJ Infect Dis2012206111724173322984115
  • MullerHJSome genetic aspects of sexAm Nat193266703118138
  • EldholmVNorheimGvon der LippeBEvolution of extensively drug-resistant Mycobacterium tuberculosis from a susceptible ancestor in a single patientGenome Biol2014151149025418686
  • GreenKDGarneau-TsodikovaSResistance in tuberculosis: what do we know and where can we go?Front Microbiol2013420823888158
  • FavrotLRonningDRTargeting the mycobacterial envelope for tuberculosis drug developmentExpert Rev Anti Infect Ther20121091023103623106277
  • ForrelladMAKleppLIGioffreAVirulence factors of the Mycobacterium tuberculosis complexVirulence20134136623076359
  • SinghAGuptaRVishwakarmaRARequirement of the mymA operon for appropriate cell wall ultrastructure and persistence of Mycobacterium tuberculosis in the spleens of guinea pigsJ Bacteriol2005187124173418615937179
  • SinghAJainSGuptaSDasTTyagiAKmymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelopeFEMS Microbiol Lett20032271536314568148
  • GaoLYLavalFLawsonEHRequirement for kasB in Mycobacterium mycolic acid biosynthesis, cell wall impermeability and intracellular survival: implications for therapyMol Microbiol20034961547156312950920
  • PhilalayJSPalermoCOHaugeKARustadTRCangelosiGAGenes required for intrinsic multidrug resistance in Mycobacterium aviumAntimicrob Agents Chemother20044893412341815328105
  • SinghGSinghGJadejaDKaurJLipid hydrolyzing enzymes in virulence: Mycobacterium tuberculosis as a model systemCrit Rev Microbiol201036325926920500016
  • SinghPRaoRNReddyJRPE11, a PE/PPE family protein of Mycobacterium tuberculosis is involved in cell wall remodeling and virulenceSci Rep201662162426902658
  • MarrakchiHLaneelleMADaffeMMycolic acids: structures, biosynthesis, and beyondChem Biol2014211678524374164
  • BanerjeeADubnauEQuemardAinhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosisScience199426351442272308284673
  • TelentiAPhilippWJSreevatsanSThe emb operon, a gene cluster of Mycobacterium tuberculosis involved in resistance to ethambutolNat Med1997355675709142129
  • AlcaideFPfyfferGETelentiARole of embB in natural and acquired resistance to ethambutol in mycobacteriaAntimicrob Agents Chemother19974110227022739333060
  • SafiHSayersBHazbonMHAllandDTransfer of embB codon 306 mutations into clinical Mycobacterium tuberculosis strains alters susceptibility to ethambutol, isoniazid, and rifampinAntimicrob Agents Chemother20085262027203418378710
  • SafiHLingarajuSAminAEvolution of high-level ethambutol-resistant tuberculosis through interacting mutations in decaprenylphosphoryl-beta-D-arabinose biosynthetic and utilization pathway genesNat Genet201345101190119723995136
  • ZhaoLLSunQLiuHCAnalysis of embCAB mutations associated with ethambutol resistance in multidrug-resistant Mycobacterium tuberculosis isolates from ChinaAntimicrob Agents Chemother20155942045205025605360
  • XuYJiaHHuangHSunZZhangZMutations Found in embCAB, embR, and ubiA genes of ethambutol-sensitive and -resistant Mycobacterium tuberculosis clinical isolates from ChinaBiomed Res Int20159517061031
  • NguyenLAntibiotic resistance mechanisms in M. tuberculosis: an updateArch Toxicol20169071585160427161440
  • SunJDengZYanABacterial multidrug efflux pumps: mechanisms, physiology and pharmacological exploitationsBiochem Biophys Res Commun2014453225426724878531
  • LiuHXieJPComparative genomics of Mycobacterium tuberculosis drug efflux pumps and their transcriptional regulatorsCrit Rev Eukaryot Gene Expr201424216318024940769
  • LiGZhangJGuoQEfflux pump gene expression in multidrug-resistant Mycobacterium tuberculosis clinical isolatesPLoS One2015102e011901325695504
  • ZhangSChenJCuiPShiWZhangWZhangYIdentification of novel mutations associated with clofazimine resistance in Mycobacterium tuberculosisJ Antimicrob Chemother20157092507251026045528
  • KanjiAHasanRZaverAAlternate efflux pump mechanism may contribute to drug resistance in extensively drug-resistant isolates of Mycobacterium tuberculosisInt J Mycobacteriol20165suppl 1S97S9828043640
  • KanjiAHasanRZhangYIncreased expression of efflux pump genes in extensively drug-resistant isolates of Mycobacterium tuberculosisInt J Mycobacteriol20165suppl 1S15028043519
  • OhTSKimYJKangHYKimCKChoSYLeeHJRNA expression analysis of efflux pump genes in clinical isolates of multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis in South KoreaInfection, genetics and evolution: journal of molecular epidemiology and evolutionary genetics in infectious diseases201749111115
  • ReevesAZCampbellPJSultanaRAminoglycoside cross-resistance in Mycobacterium tuberculosis due to mutations in the 5′ untranslated region of whiB7Antimicrob Agents Chemother20135741857186523380727
  • AinsaJABlokpoelMCOtalIYoungDBDe SmetKAMartinCMolecular cloning and characterization of Tap, a putative multidrug efflux pump present in Mycobacterium fortuitum and Mycobacterium tuberculosisJ Bacteriol199818022583658439811639
  • BurianJRamon-GarciaSSweetGGomez-VelascoAAv-GayYThompsonCJThe mycobacterial transcriptional regulator whiB7 gene links redox homeostasis and intrinsic antibiotic resistanceJ Biol Chem2012287129931022069311
  • MorrisRPNguyenLGatfieldJAncestral antibiotic resistance in Mycobacterium tuberculosisProc Natl Acad Sci U S A200510234122001220516103351
  • SongLWuXDevelopment of efflux pump inhibitors in antituberculosis therapyInt J Antimicrob Agents201647642142927211826
  • de KnegtGJvan der MeijdenAde VogelCPAarnoutseREde SteenwinkelJEActivity of moxifloxacin and linezolid against Mycobacterium tuberculosis in combination with potentiator drugs verapamil, timcodar, colistin and SQ109Int J Antimicrob Agents201749330230728162983
  • GrossmanTHShoenCMJonesSMJonesPLCynamonMHLocherCPThe efflux pump inhibitor timcodar improves the potency of antimycobacterial agentsAntimicrob Agents Chemother20155931534154125534740
  • KumarMSinghKNaranKDesign, synthesis, and evaluation of novel hybrid efflux pump inhibitors for use against Mycobacterium tuberculosisACS infectious diseases201621071472527737555
  • BuriankovaKDoucet-PopulaireFDorsonOMolecular basis of intrinsic macrolide resistance in the Mycobacterium tuberculosis complexAntimicrob Agents Chemother200448114315014693532
  • ZaunbrecherMASikesRDJrMetchockBShinnickTMPoseyJEOverexpression of the chromosomally encoded aminoglycoside acetyltransferase Eis confers kanamycin resistance in Mycobacterium tuberculosisProc Natl Acad Sci U S A200910647200042000919906990
  • ChenWBiswasTPorterVRTsodikovOVGarneau-TsodikovaSUnusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TBProc Natl Acad Sci U S A2011108249804980821628583
  • HoughtonJLGreenKDPricerREMayhoubASGarneau-TsodikovaSUnexpected N-acetylation of capreomycin by mycobacterial Eis enzymesJ Antimicrob Chemother201368480080523233486
  • MaloneKMGordonSVAntibiotic methylation: a new mechanism of antimicrobial resistanceTrends Microbiol2016241077177227593675
  • AndrioleVTThe quinolones: past, present, and futureClin Infect Dis20051541S113S119
  • MonteroCMateuGRodriguezRTakiffHIntrinsic resistance of Mycobacterium smegmatis to fluoroquinolones may be influenced by new pentapeptide protein MfpAAntimicrob Agents Chemother200145123387339211709313
  • FerberDBiochemistry. Protein that mimics DNA helps tuberculosis bacteria resist antibioticsScience20053085727139315933168
  • HegdeSSVettingMWRoderickSLA fluoroquinolone resistance protein from Mycobacterium tuberculosis that mimics DNAScience200530857271480148315933203
  • VettingMWHegdeSSFajardoJEPentapeptide repeat proteinsBiochemistry200645111016388575
  • WarrierTKapilashramiKArgyrouAN-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosisProc Natl Acad Sci USA201611331E4523E453027432954