Novel vancomycin-peptide conjugate as potent antibacterial agent against vancomycin-resistant Staphylococcus aureus

References

• Tan RM, Liu JL, Li ML, Huang J, Sun JY, Qu HP. Epidemiology and antimicrobial resistance among commonly encountered bacteria associated with infections and colonization in intensive care units in a university-affiliated hospital in Shanghai. J Microbiol Immunol Infect. 2014;47(2):87–94.
   PubMedGoogle Scholar
• McNeece G, Naughton V, Woodward MJ, Dooley JSG, Naughton PJ. Array based detection of antibiotic resistance genes in Gram negative bacteria isolated from retail poultry meat in the UK and Ireland. Int J Food Microbiol. 2014;179:24–32.
   PubMed Web of Science ®Google Scholar
• Juknius T, Tamulevicius T, Grazuleviciute I, Klimiene I, Matusevicius AP, Tamulevicius S. In-situ measurements of bacteria resistance to antimicrobial agents employing leaky mode sub-wavelength diffraction grating. Sens Actuator B Chem. 2014;204:799–806.
   Web of Science ®Google Scholar
• Wang RX, Wang AL, Wang JY. Antibiotic resistance monitoring in heterotrophic bacteria from anthropogenic-polluted seawater and the intestines of oyster Crassostrea hongkongensis. Ecotoxicol Environ Saf. 2014;109:27–31.
   PubMed Web of Science ®Google Scholar
• Wang HH, Schaffner DW. Antibiotic resistance: how much do we know and where do we go from here? Appl Environ Microbiol. 2011;77(20):7093–7095.
   PubMed Web of Science ®Google Scholar
• Cui LZ, Iwamoto A, Lian JQ, et al. Novel mechanism of antibiotic resistance originating in vancomycin-intermediate Staphylococcus aureus. Antimicrob Agents Chemother. 2006;50(2):428–438.
   PubMed Web of Science ®Google Scholar
• Chang S, Sievert DM, Hageman JC, et al; Vancomycin-Resistant Staphylococcus aureus Investigative Team. Infection with vancomycin-resistant Staphylococcus aureus containing the vanA resistance gene. N Engl J Med. 2003;348(14):1342–1347.
   PubMed Web of Science ®Google Scholar
• Chung DR, Baek JY, Kim HA, et al. First report of vancomycin-intermediate resistance in sequence type 72 community genotype methicillin-resistant Staphylococcus aureus. J Clin Microbiol. 2012;50(7):2513–2514.
   PubMed Web of Science ®Google Scholar
• Weigel LM, Clewell DB, Gill SR, et al. Genetic analysis of a high-level vancomycin-resistant isolate of Staphylococcus aureus. Science. 2003;302(5650):1569–1571.
   PubMed Web of Science ®Google Scholar
• Courvalin P. Vancomycin resistance in gram-positive cocci. Clin Infect Dis. 2006;42(suppl 1):S25–S34.
   PubMedGoogle Scholar
• Alexander EL, Gardete S, Bar HY, Wells MT, Tomasz A, Rhee KY. Intermediate-type vancomycin resistance (VISA) in genetically-distinct Staphylococcus aureus isolates is linked to specific, reversible metabolic alterations. PLoS One. 2014;9(5):1–9.
   Web of Science ®Google Scholar
• Zhu WL, Lan HL, Park IS, et al. Design and mechanism of action of a novel bacteria-selective antimicrobial peptide from the cell-penetrating peptide Pep-1. Biochem Biophys Res Commun. 2006;349(2):769–774.
   PubMed Web of Science ®Google Scholar
• Groh T, Hrabeta J, Khalil MA, Doktorova H, Eckschlager T, Stiborova M. The synergistic effects of DNA-damaging drugs cisplatin and etoposide with a histone deacetylase inhibitor valproate in high-risk neuroblastoma cells. Int J Oncol. 2015;47(1):343–352.
   PubMed Web of Science ®Google Scholar
• Piecyk K, Jankowska-Anyszka M. Chemical conjugation of an mRNA cap analogue with a cell-penetrating peptide as a potential membrane permeable translation inhibitor. Tetrahedron Lett. 2014;55(3):606–609.
   Web of Science ®Google Scholar
• Montenegro J, Matile S. Anionic activators for differential sensing with cell-penetrating peptides. Chem Asian J. 2011;6(2):681–689.
   PubMed Web of Science ®Google Scholar
• Sanches PRS, Carneiro BM, Batista MN, et al. A conjugate of the lytic peptide Hecate and gallic acid: structure, activity against cervical cancer, and toxicity. Amino Acids. 2015;47(7):1433–1443.
   PubMed Web of Science ®Google Scholar
• Rivero-Muller A, Vuorenoja S, Tuominen M, et al. Use of hecate-chorionic gonadotropin beta conjugate in therapy of lutenizing hormone receptor expressing gonadal somatic cell tumors. Mol Cell Endocrinol. 2007;269(1–2):17–25.
   PubMed Web of Science ®Google Scholar
• Vicente EF, Basso LGM, Cespedes GF, et al. Dynamics and conformational studies of TOAC spin labeled analogues of Ctx(Ile(21))-Ha peptide from Hypsiboas albopunctatus. PLoS One. 2013;8(4):1–12.
   Web of Science ®Google Scholar
• Chudobova D, Cihalova K, Dostalova S, et al. Comparison of the effects of silver phosphate and selenium nanoparticles on Staphylococcus aureus growth reveals potential for selenium particles to prevent infection. FEMS Microbiol Lett. 2014;351(2):195–201.
   PubMed Web of Science ®Google Scholar
• Wright SJL. A simple agar plate method, using micro-algae, for herbicide bio-assay or detection. Bull Environ Contam Toxicol. 1975;14(1):65–70.
   PubMed Web of Science ®Google Scholar
• Valgas C, de Souza SM, Smania EFA, Smania A. Screening methods to determine antibacterial activity of natural products. Braz J Microbiol. 2007;38(2):369–380.
   Web of Science ®Google Scholar
• Wang HL, Hesseltine CW, Ellis JJ. Antibacterial activity produced by molds commonly used in oriental food fermentations. Mycologia. 1972;64(1):218–221.
   PubMed Web of Science ®Google Scholar
• Balouiri M, Sadiki M, Ibnsouda SK. Methods for in vitro evaluating antimicrobial activity: a review. J Pharm Anal. 2016;6(2):71–79.
   PubMed Web of Science ®Google Scholar
• Sakoulas G, Moise-Broder PA, Schentag J, Forrest A, Moellering RC, Eliopoulos GM. Relationship of MIC and bactericidal activity to efficacy of vancomycin for treatment of methicillin-resistant Staphylococcus aureus bacteremia. J Clin Microbiol. 2004;42(6):2398–2402.
   PubMed Web of Science ®Google Scholar
• Petersen PJ, Jones CH, Bradford PA. In vitro antibacterial activities of tigecycline and comparative agents by time-kill kinetic studies in fresh Mueller-Hinton broth. Diagn Microbiol Infect Dis. 2007;59(3):347–349.
   PubMed Web of Science ®Google Scholar
• Pankey GA, Ashcraft DS. In vitro antibacterial activity of tigecycline against resistant Gram-negative bacilli and enterococci by time-kill assay. Diagn Microbiol Infect Dis. 2009;64(3):300–304.
   PubMed Web of Science ®Google Scholar
• Petersen PJ, Wang TZ, Dushin RG, Bradford PA. Comparative in vitro activities of AC98-6446, a novel semisynthetic glycopeptide derivative of the natural product mannopeptimycin alpha, and other antimicrobial agents against gram-positive clinical isolates. Antimicrob Agents Chemother. 2004;48(3):739–746.
   PubMed Web of Science ®Google Scholar
• Heger Z, Rodrigo MAM, Michalek P, et al. Sarcosine up-regulates expression of genes involved in cell cycle progression of metastatic models of prostate cancer. PLoS One. 2016;11(11):1–20.
   Web of Science ®Google Scholar
• Berney M, Hammes F, Bosshard F, Weilenmann HU, Egli T. Assessment and interpretation of bacterial viability by using the LIVE/DEAD BacLight kit in combination with flow cytometry. Appl Environ Microbiol. 2007;73(10):3283–3290.
   PubMed Web of Science ®Google Scholar
• Hiramatsu K, Kayayama Y, Matsuo M, et al. Vancomycin-intermediate resistance in Staphylococcus aureus. J Glob Antimicrob Resist. 2014;2(4):213–224.
   PubMed Web of Science ®Google Scholar
• Reinhardt A, Neundorf I. Design and application of antimicrobial peptide conjugates. Int J Mol Sci. 2016;17(5):701.
   PubMed Web of Science ®Google Scholar
• Leuschner C, Hansel W. Membrane disrupting lytic peptides for cancer treatments. Curr Pharm Des. 2004;10(19):2299–2310.
   PubMed Web of Science ®Google Scholar
• Yarlagadda V, Konai MM, Manjunath GB, Ghosh C, Haldar J. Tackling vancomycin-resistant bacteria with ‘lipophilic-vancomycin-carbohydrate conjugates’. J Antibiot. 2015;68(5):302–312.
   PubMed Web of Science ®Google Scholar
• Suller MTE, Russell AD. Triclosan and antibiotic resistance in Staphylococcus aureus. J Antimicrob Chemother. 2000;46(1):11–18.
   PubMed Web of Science ®Google Scholar
• Sabath LD, Garner C, Wilcox C, Finland M. Susceptibility of Staphylococcus aureus and Staphylococcus epidermidis to 65 antibiotics. Antimicrob Agents Chemother. 1976;9(6):962–969.
   PubMed Web of Science ®Google Scholar
• Ligozzi M, Bernini C, Bonora MG, de Fatima M, Zuliani J, Fontana R. Evaluation of the VITEK 2 system for identification and antimicrobial susceptibility testing of medically relevant gram-positive cocci. J Clin Microbiol. 2002;40(5):1681–1686.
   PubMed Web of Science ®Google Scholar
• Andrews JM. Determination of minimum inhibitory concentrations. J Antimicrob Chemother. 2001;48(suppl 1):5–16.
   PubMed Web of Science ®Google Scholar
• Abb J. In vitro activity of linezolid, quinupristin-dalfopristin, vancomycin, teicoplanin, moxifloxacin and mupirocin against methicillin-resistant Staphylococcus aureus: comparative evaluation by the E test and a broth microdilution method. Diagn Microbiol Infect Dis. 2002;43(4):319–321.
   PubMed Web of Science ®Google Scholar
• Goudarzi M, Goudarzi H, Figueiredo AMS, et al. Molecular characterization of methicillin resistant Staphylococcus aureus strains isolated from intensive care units in Iran: ST22-SCCmec IV/t790 emerges as the major clone. PLoS One. 2016;11(5):1–13.
   Web of Science ®Google Scholar
• Baker-Austin C, Wright MS, Stepanauskas R, McArthur JV. Co-selection of antibiotic and metal resistance. Trends Microbiol. 2006;14(4):176–182.
   PubMed Web of Science ®Google Scholar
• Hallbrink M, Oehlke J, Papsdorf G, Bienert M. Uptake of cell-penetrating peptides is dependent on peptide-to-cell ratio rather than on peptide concentration. Biochim Biophys Acta. 2004;1667(2):222–228.
   PubMed Web of Science ®Google Scholar
• Perichon B, Courvalin P. VanA-type vancomycin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2009;53(11):4580–4587.
   PubMed Web of Science ®Google Scholar