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Case Report

Whole-genome characterization and resistance-associated substitutions in a new HCV genotype 1 subtype

, , , , , , & show all
Pages 947-955 | Published online: 24 Apr 2019

References

  • United Nations-General Assembly. Global hepatitis report 2017. WHO; 2017 Available from: http://www.who.int/hepatitis/publications/global-hepatitis-report2017/en/.2017/p1-83ed.
  • Smith D. HCV classification. A web resource to manage the classifcation and genotype and subtype assignements of hepatits virus; 2018 Available from: https://talk.ictvonline.org/ictv_wikis/flaviviridae/w/sg_flavi/56/hcv-classification.
  • Smith DB, Bukh J, Kuiken C, et al. Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: updated criteria and assignment web resource. Hepatology. 2014;59:318–327. doi:10.1002/hep.2674424115039
  • Martell M, Esteban JI, Quer J, et al. Hepatitis C virus (HCV) circulates as a population of different but closely related genomes: quasispecies nature of HCV genome distribution. J Virol. 1992;66:3225–3229.1313927
  • Vermehren J, Sarrazin C. The role of resistance in HCV treatment. Best Pract Res Clin Gastroenterol. 2012;26:487–503. doi:10.1016/j.bpg.2012.09.01123199507
  • Eltahla AA, Leung P, Pirozyan MR, et al. Dynamic evolution of hepatitis C virus resistance-associated substitutions in the absence of antiviral treatment. Sci Rep. 2017;7:41719. doi:10.1038/srep4171928139734
  • EASL. EASL recommendations on treatment of hepatitis C 2018. J Hepatol. 2018;69:461–511. doi:10.1016/j.jhep.2018.03.02629650333
  • Lontok E, Harrington P, Howe A, et al. Hepatitis C virus drug resistance-associated substitutions: state of the art summary. Hepatology. 2015;62:1623–1632. doi:10.1002/hep.2793426095927
  • Sarrazin C. The importance of resistance to direct antiviral drugs in HCV infection in clinical practice. J Hepatol. 2016;64:486–504. doi:10.1016/j.jhep.2015.09.01126409317
  • Quer J, Gregori J, Rodriguez-Frias F, et al. High-resolution hepatitis C virus subtyping using NS5B deep sequencing and phylogeny, an alternative to current methods. J Clin Microbiol. 2015;53:219–226. doi:10.1128/JCM.02093-1425378574
  • Ordeig L, Garcia-Cehic D, Gregori J, et al. New hepatitis C virus genotype 1 subtype naturally harbouring resistance-associated mutations to NS5A inhibitors. J Gen Virol. 2018;99:97–102. doi:10.1099/jgv.0.00099629239718
  • Rodriguez-Frias F, Nieto-Aponte L, Gregori J, et al. High HCV subtype heterogeneity in a chronically infected general population revealed by high-resolution hepatitis C virus subtyping. Clin Microbiol Infect. 2017;23:775e1–775e6. doi:10.1016/j.cmi.2017.02.00728192235
  • Kuiken C, Combet C, Bukh J, et al. A comprehensive system for consistent numbering of HCV sequences, proteins and epitopes. Hepatology. 2006;44:1355–1361. doi:10.1002/hep.2137717058236
  • R Core Team. R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing; 2016.
  • Edgar RC. MUSCLE: a multiple sequence alignment method with reduced time and space complexity. BMC Bioinformatics. 2004;5:113. doi:10.1186/1471-2105-5-11315318951
  • Perales C, Chen Q, Soria ME, et al. Baseline hepatitis C virus resistance-associated substitutions present at frequencies lower than 15% may be clinically significant. Infect Drug Res. 2018;11:2207–2210.
  • Palanisamy N, Kalaghatgi P, Akaberi D, et al. Worldwide prevalence of baseline resistance-associated polymorphisms and resistance mutations in HCV against current direct-acting antivirals. Antivir Ther. 2018;23:485–493. doi:10.3851/IMP323729745936
  • Sorbo MC, Cento V, Di Maio V, et al. Hepatitis C virus drug resistance associated substitutions and their clinical relevance: update 2018. Drug Resist Updat. 2018;37:17–39. doi:10.1016/j.drup.2018.01.00429525636
  • Lawitz E, Yang JC, Stamm LM, et al. Characterization of HCV resistance from a 3-day monotherapy study of voxilaprevir, a novel pangenotypic NS3/4A protease inhibitor. Antivir Ther. 2018;23:325–334. doi:10.3851/IMP320229063860