100
Views
13
CrossRef citations to date
0
Altmetric
Short Report

Rapid Carbapenemase Detection With Xpert Carba-R V2 Directly On Positive Blood Vials

, , ORCID Icon, , , ORCID Icon, & show all
Pages 3311-3316 | Published online: 23 Oct 2019

References

  • Seifert H. The clinical importance of microbiological findings in the diagnosis and management of bloodstream infections. Clin Infect Dis Off Publ Infect Dis Soc Am. 2009;48(Suppl 4):S238–S245. doi:10.1086/598188
  • Logan LK, Weinstein RA. The epidemiology of carbapenem-resistant Enterobacteriaceae: the impact and evolution of a global menace. J Infect Dis. 2017;215(suppl_1):S28–S36. doi:10.1093/infdis/jiw28228375512
  • Nordmann P, Poirel L, Dortet L. Rapid detection of carbapenemase-producing Enterobacteriaceae. Emerg Infect Dis. 2012;18(9):1503–1507. doi:10.3201/eid1809.12035522932472
  • Birgy A, Bidet P, Genel N, et al. Phenotypic screening of carbapenemases and associated β-lactamases in carbapenem-resistant Enterobacteriaceae. J Clin Microbiol. 2012;50(4):1295–1302. doi:10.1128/JCM.06131-1122259214
  • Caméléna F, Cointe A, Mathy V, et al. Within-a-day detection and rapid characterization of carbapenemase by use of a new carbapenem inactivation method-based test, CIMplus. J Clin Microbiol. 2018;56:9. doi:10.1128/JCM.00137-18
  • Papagiannitsis CC, Študentová V, Izdebski R, et al. Matrix-assisted laser desorption ionization-time of flight mass spectrometry meropenem hydrolysis assay with NH4HCO3, a reliable tool for direct detection of carbapenemase activity. J Clin Microbiol. 2015;53(5):1731–1735. doi:10.1128/JCM.03094-1425694522
  • Cointe A, Bonacorsi S, Truong J, et al. Detection of carbapenemase-producing enterobacteriaceae in positive blood culture using an immunochromatographic RESIST-4 O.K.N.V. assay. Antimicrob Agents Chemother. 2018;62(12). doi:10.1128/AAC.01828-18
  • Smith M, Diederen B, Scharringa J, Leversteijn-van Hall M, Fluit AC, Cohen Stuart J. Rapid and accurate detection of carbapenemase genes in Enterobacteriaceae with the Cepheid Xpert Carba-R assay. J Med Microbiol. 2016;65(9):951–953. doi:10.1099/jmm.0.00031027451855
  • O’Connor C, Kiernan MG, Finnegan C, et al. An optimized work-flow to reduce time-to-detection of carbapenemase-producing Enterobacteriaceae (CPE) using direct testing from rectal swabs. Bioengineered. 2017;8(3):217–224. doi:10.1080/21655979.2016.122233527533488
  • Cortegiani A, Russotto V, Graziano G, et al. Use of Cepheid Xpert Carba-R® for rapid detection of carbapenemase-producing bacteria in abdominal septic patients admitted to intensive care unit. PLoS One. 2016;11(8):e0160643. doi:10.1371/journal.pone.016064327490684
  • Burillo A, Marín M, Cercenado E, et al. Evaluation of the Xpert Carba-R (Cepheid) assay using contrived bronchial specimens from patients with suspicion of ventilator-associated pneumonia for the detection of prevalent carbapenemases. PLoS One. 2016;11(12):e0168473. doi:10.1371/journal.pone.016847327992521
  • Robert J, Pantel A, Mérens A, Lavigne J-P, Nicolas-Chanoine M-H; ONERBA’s Carbapenem Resistance Study Group. Incidence rates of carbapenemase-producing Enterobacteriaceae clinical isolates in France: a prospective nationwide study in 2011-12. J Antimicrob Chemother. 2014;69(10):2706–2712. doi:10.1093/jac/dku20824942333
  • Carvalhaes CG, Cayô R, Visconde MF, et al. Detection of carbapenemase activity directly from blood culture vials using MALDI-TOF MS: a quick answer for the right decision. J Antimicrob Chemother. 2014;69(8):2132–2136. doi:10.1093/jac/dku09424722840
  • Dortet L, Bréchard L, Poirel L, Nordmann P. Rapid detection of carbapenemase-producing Enterobacteriaceae from blood cultures. Clin Microbiol Infect. 2014;20(4):340–344. doi:10.1111/1469-0691.1231823889766
  • Rodríguez-Baño J, Gutiérrez-Gutiérrez B, Machuca I, Pascual A. Treatment of infections caused by extended-spectrum-beta-lactamase-, AmpC-, and carbapenemase-producing Enterobacteriaceae. Clin Microbiol Rev. 2018;31(2). doi:10.1128/CMR.00079-17
  • Jauréguy F, Mansour H, Bigot J, et al. Use of the Xpert CarbaR assay for direct detection of carbapenemase genes from blood cultures and urine samples. J Hosp Infect. 2018;98(3):245–246. doi:10.1016/j.jhin.2017.09.02628970052
  • Dortet L, Cuzon G, Ponties V, Nordmann P. Trends in carbapenemase-producing Enterobacteriaceae, France, 2012 to 2014. Euro Surveill Bull Eur Sur Mal Transm Eur Commun Dis Bull. 2017;22(6). doi:10.2807/1560-7917.ES.2017.22.6.30461