Molecular characterization and prevalence of antibiotic resistance in Helicobacter pylori isolates in Kuala Lumpur, Malaysia

References

• Hooi JKY, Lai WY, Ng WK. Global prevalence of Helicobacter pylori infection: systematic review and meta-analysis. Gastroenterology 2017;153:420–429.
   Google Scholar
• Ozbey G, Demirel U, Aygun C, Ertas HB. Investigation of the association between clinical outcome and the cag pathogenicity-island and other virulence genes of Helicobacter pylori isolates from patients with dyspepsia in Eastern Turkey. Brazilian J Microbiol. 2013;44(4):1267–1274. doi:10.1590/S1517-83822013000400034
   Web of Science ®Google Scholar
• Brown LM. Helicobacter pylori: epidemiology and routes of transmission. Epidemiol Rev. 2000;22(2):283–297. doi:10.1093/oxfordjournals.epirev.a01804011218379
   PubMed Web of Science ®Google Scholar
• Jones NL, Koletzko S, Goodman K, et al. Joint ESPGHAN/NASPGHAN guidelines for the management of Helicobacter pylori in children and adolescents (update 2016). J Pediatr Gastroenterol Nutr. 2017;64(6):991–1003.28541262
   PubMed Web of Science ®Google Scholar
• Malfertheiner P, Megraud F, O’Morain CA, et al. Management of Helicobacter pylori infection – the Maastricht IV/Florence Consensus Report. Gut. 2012;61(5):646–664. doi:10.1136/gutjnl-2012-30208422491499
   PubMed Web of Science ®Google Scholar
• Megraud F. H. pylori antibiotic resistance: prevalence, importance, and advances in testing. Gut. 2004;53(9):1374–1384. doi:10.1136/gut.2003.02211115306603
   PubMed Web of Science ®Google Scholar
• Wu W, Yang Y, Sun G. Recent insights into antibiotic resistance in Helicobacter pylori eradication. Gastroenterol Res Pract. 2012;2012. doi:10.1155/2012/585674
   Web of Science ®Google Scholar
• Alfizah H, Norazah A, Hamizah R, Ramelah M. Resistotype of Helicobacter pylori isolates: the impact on eradication outcome. J Med Microbiol. 2014;63(5):703–709. doi:10.1099/jmm.0.069781-024757218
   PubMed Web of Science ®Google Scholar
• De Francesco V, Zullo A, Ierardi E, Vaira D. Minimal inhibitory concentration (MIC) values and different point mutations in the 23S rRNA gene for clarithromycin resistance in Helicobacter pylori. Dig Liver Dis. 2009;41(8):610–611. doi:10.1016/j.dld.2009.01.00119200790
   PubMedGoogle Scholar
• Boyanova L, Markovska R, Yordanov D, Gergova G, Mitov I. Clarithromycin resistance mutations in Helicobacter pylori in association with virulence factors and antibiotic susceptibility of the strains. Microb Drug Resist. 2016;22(3):227–232. doi:10.1089/mdr.2015.019926618567
   PubMed Web of Science ®Google Scholar
• Matta AJ, Zambrano DC, Pazos AJ. Punctual mutations in 23S rRNA gene of clarithromycin-resistant Helicobacter pylori in Colombian populations. World J Gastroenterol. 2018;24(14):1531. doi:10.3748/wjg.v24.i14.153129662291
   PubMed Web of Science ®Google Scholar
• Kim JM, Kim JS, Kim N, et al. Gene mutations of 23S rRNA associated with clarithromycin resistance in Helicobacter pylori strains isolated from Korean patients. J Microbiol Biotechnol. 2008;18(9):1584–1589.18852516
   PubMed Web of Science ®Google Scholar
• Rimbara E, Noguchi N, Kawai T, Sasatsu M. Novel mutation in 23S rRNA that confers low-level resistance to clarithromycin in Helicobacter pylori. Antimicrob Agents Chemother. 2008;52(9):3465–3466. doi:10.1128/AAC.00445-0818606842
   PubMed Web of Science ®Google Scholar
• Tsugawa H, Suzuki H, Muraoka H, et al. Enhanced bacterial efflux system is the first step to the development of metronidazole resistance in Helicobacter pylori. Biochem Biophys Res Commun. 2011;404(2):656–660. doi:10.1016/j.bbrc.2010.12.03421147064
   PubMed Web of Science ®Google Scholar
• Rimbara E, Noguchi N, Kawai T, Sasatsu M. Fluoroquinolone resistance in Helicobacter pylori: role of mutations at position 87 and 91 of GyrA on the level of resistance and identification of a resistance conferring mutation in GyrB. Helicobacter. 2012;17(1):36–42. doi:10.1111/j.1523-5378.2011.00912.x
   Web of Science ®Google Scholar
• Tseng Y, Wu D, Chang C, et al. Amoxicillin resistance with β‐lactamase production in Helicobacter pylori. Eur J Clin Invest. 2009;39(9):807–812. doi:10.1111/j.1365-2362.2009.02166.x19614952
   PubMed Web of Science ®Google Scholar
• Toledo H, López-Solís R. Tetracycline resistance in Chilean clinical isolates of Helicobacter pylori. J Antimicrob Chemother. 2009;65(3):470–473. doi:10.1093/jac/dkp45720035020
   PubMed Web of Science ®Google Scholar
• Heep M, Beck D, Bayerdorffer E, Lehn N. Rifampin and rifabutin resistance mechanism in Helicobacter pylori. Antimicrob Agents Chemother. 1999;43(6):1497–1499.10348780
   PubMed Web of Science ®Google Scholar
• Graham DY, Lee Y, Wu M. Rational Helicobacter pylori therapy: evidence-based medicine rather than medicine-based evidence. Clin Gastroenterol Hepatol. 2014;12(2):177–186.e3. doi:10.1016/j.cgh.2013.05.02823751282
   PubMed Web of Science ®Google Scholar
• Fadilah N, Hanafiah A, Razlan H, Wong ZQ, Mohamed Rose I, Rahman MM. Multiplex PCR for detection of Helicobacter pylori infection in gastric biopsies with lower inflammatory score. Br J Biomed Sci. 2016;73(4):180–187. doi:10.1080/09674845.2016.122070527922429
   PubMed Web of Science ®Google Scholar
• Kim SY, Woo CW, Lee YM, et al. Genotyping CagA, VacA subtype, IceA1, and BabA of Helicobacter pylori isolates from Korean patients, and their association with gastroduodenal diseases. J Korean Med Sci. 2001;16(5):579–584. doi:10.3346/jkms.2001.16.5.57911641526
   PubMed Web of Science ®Google Scholar
• Francesco VD, Zullo A, Hassan C, Giorgio F, Rosania R, Ierardi E. Mechanisms of Helicobacter pylori antibiotic resistance: an updated appraisal. World J Gastrointest Pathophysiol. 2011;2(3):35–41. doi:10.4291/wjgp.v2.i3.3521860834
   PubMedGoogle Scholar
• Kim JM, Kim JS, Kim N, Jung HC, Song IS. Distribution of fluoroquinolone MICs in Helicobacter pylori strains from Korean patients. J Antimicrob Chemother. 2005;56(5):965–967. doi:10.1093/jac/dki33416159928
   PubMed Web of Science ®Google Scholar
• Monno R, Fumarola L, Capolongo C, et al. Susceptibility of Helicobacter pylori to antibiotics including tigecycline. J Med Microbiol Diagn. 2015;S5:1.
   Google Scholar
• Chisholm SA, Owen RJ. Frequency and molecular characteristics of ciprofloxacin-and rifampicin-resistant Helicobacter pylori from gastric infections in the UK. J Med Microbiol. 2009;58(10):1322–1328. doi:10.1099/jmm.0.011270-019589906
   PubMed Web of Science ®Google Scholar
• CLSI. Performance Standards for Antimicrobial Susceptibility Testing; Twentieth Informational Supplement. MIC Interpretive Standards for Helicobacter Pylori. Wayne (PA): Clinical and Laboratory Standards Institute (CLSI); 2010.
   Google Scholar
• Marais A, Bilardi C, Cantet F, Mendz GL, Mégraud F. Characterization of the genes rdxA and frxA involved in metronidazole resistance in Helicobacter pylori. Res Microbiol. 2003;154(2):137–144. doi:10.1016/S0923-2508(03)00030-512648728
   PubMed Web of Science ®Google Scholar
• Ribeiro ML, Vitiello L, Miranda MC, et al. Mutations in the 23S rRNA gene are associated with clarithromycin resistance in Helicobacter pylori isolates in Brazil. Ann Clin Microbiol Antimicrob. 2003;2(1):11. doi:10.1186/1476-0711-2-1114633281
   PubMedGoogle Scholar
• Wueppenhorst N, Stueger H, Kist M, Glocker E. Identification and molecular characterization of triple-and quadruple-resistant Helicobacter pylori clinical isolates in Germany. J Antimicrob Chemother. 2009;63(4):648–653. doi:10.1093/jac/dkp00319190100
   PubMed Web of Science ®Google Scholar
• Akopyanz N, Bukanov NO, Westblom TU, Kresovich S, Berg DE. DNA diversity among clinical isolates of Helicobacter pylori detected by PCR-based RAPD fingerprinting. Nucleic Acids Res. 1992;20(19):5137–5142. doi:10.1093/nar/20.19.51371408828
   PubMed Web of Science ®Google Scholar
• Peleteiro B, Bastos A, Ferro A, Lunet N. Prevalence of Helicobacter pylori infection worldwide: a systematic review of studies with national coverage. Dig Dis Sci. 2014;59(8):1698–1709. doi:10.1007/s10620-014-3063-024563236
   PubMed Web of Science ®Google Scholar
• Alfizah H, Rizal A, Isa M, Aminuddin A, Jasmi A, Ramelah M. Four year analysis of Helicobacter pylori infection among patients with dyspepsia in Universiti Kebangsaan Malaysia Medical Centre. Med Health. 2010;5:13–21.
   Google Scholar
• Sasidharan S, Lachumy SJT, Ravichandran M, Latha LY, Gegu SRS. Epidemiology of Helicobacter pylori among multiracial community in Northern Peninsular, Malaysia: effect of age across race and gender. Asian Pac J Trop Med. 2011;4(1):72–75. doi:10.1016/S1995-7645(11)60037-021771421
   PubMed Web of Science ®Google Scholar
• Yu CJ, Yan P, Yee LY. Prevalence of Helicobacter pylori infection among patients attending gastroenterology endoscopy unit at Serdang Hospital. Malaysian J Med Health Sci. 2015;11(1):11–17.
   Google Scholar
• Huang JQ, Hunt RH. Treatment after failure: the problem of “non-responders”. Gut. 1999;45 Suppl 1:I40–I44.10457036
   PubMed Web of Science ®Google Scholar
• Ghotaslou R, Leylabadlo HE, Asl YM. Prevalence of antibiotic resistance in Helicobacter pylori: a recent literature review. World J Methodol. 2015;5(3):164–174. doi:10.5662/wjm.v5.i3.16426413490
   PubMedGoogle Scholar
• Ahmad N, Zakaria WR, Mohamed R. Analysis of antibiotic susceptibility patterns of Helicobacter pylori isolates from Malaysia. Helicobacter. 2011;16(1):47–51. doi:10.1111/j.1523-5378.2010.00816.x21241412
   PubMed Web of Science ®Google Scholar
• Teh X, Khosravi Y, Lee WC, et al. Functional and molecular surveillance of Helicobacter pylori antibiotic resistance in Kuala Lumpur. PLoS One. 2014;9(7):e101481. doi:10.1371/journal.pone.010148125003707
   PubMed Web of Science ®Google Scholar
• Binh TT, Shiota S, Nguyen LT, et al. The incidence of primary antibiotic resistance of Helicobacter pylori in Vietnam. J Clin Gastroenterol. 2013;47(3):233–238. doi:10.1097/MCG.0b013e3182676e2b23090037
   PubMed Web of Science ®Google Scholar
• Vilaichone R, Gumnarai P, Ratanachu-Ek T, Mahachai V. Nationwide survey of Helicobacter pylori antibiotic resistance in Thailand. Diagn Microbiol Infect Dis. 2013;77(4):346–349. doi:10.1016/j.diagmicrobio.2013.08.01024094837
   PubMed Web of Science ®Google Scholar
• Ang TL, Fock KM, Ang D, Kwek ABE, Teo EK, Dhamodaran S. The changing profile of Helicobacter pylori antibiotic resistance in Singapore: a 15‐year study. Helicobacter. 2016;21(4):261–265. doi:10.1111/hel.1229126774006
   PubMed Web of Science ®Google Scholar
• Goh K, Navaratnam P. High Helicobacter pylori resistance to metronidazole but zero or low resistance to clarithromycin, levofloxacin, and other antibiotics in Malaysia. Helicobacter. 2011;16(3):241–245. doi:10.1111/j.1523-5378.2011.00841.x21585611
   PubMed Web of Science ®Google Scholar
• Thung I, Aramin H, Vavinskaya V, et al. the global emergence of Helicobacter pylori antibiotic resistance. Aliment Pharmacol Ther. 2016;43(4):514–533. doi:10.1111/apt.1349726694080
   PubMed Web of Science ®Google Scholar
• Kim JJ, Kim JG, Kwon DH. Mixed‐infection of antibiotic susceptible and resistant Helicobacter pylori isolates in a single patient and underestimation of antimicrobial susceptibility testing. Helicobacter. 2003;8(3):202–206.12752732
   PubMed Web of Science ®Google Scholar
• Rimbara E, Noguchi N, Tanabe M, Kawai T, Matsumoto Y, Sasatsu M. Susceptibilities to clarithromycin, amoxycillin and metronidazole of Helicobacter pylori isolates from the antrum and corpus in Tokyo, Japan, 1995–2001. Clin Microbiol Infect. 2005;11(4):307–311. doi:10.1111/j.1469-0691.2005.01099.x15760428
   PubMed Web of Science ®Google Scholar
• Selgrad M, Tammer I, Langner C, et al. Different antibiotic susceptibility between antrum and corpus of the stomach, a possible reason for treatment failure of Helicobacter pylori infection. World J Gastroenterol. 2014;20(43):16245–16251. doi:10.3748/wjg.v20.i43.1624525473179
   PubMed Web of Science ®Google Scholar
• Mascellino MT, Porowska B, De Angelis M, Oliva A. Antibiotic susceptibility, heteroresistance, and updated treatment strategies in Helicobacter pylori infection. Drug Des Devel Ther. 2017;11:2209. doi:10.2147/DDDT.S136240
   PubMed Web of Science ®Google Scholar
• Karczewska E, Wojtas-Bonior I, Sito E, Zwolińska-Wcisło M, Budak A. Primary and secondary clarithromycin, metronidazole, amoxicillin and levofloxacin resistance to Helicobacter pylori in southern Poland. Pharmacol Rep. 2011;63(3):799–807.21857091
   PubMed Web of Science ®Google Scholar
• Di Giulio M, Di Campli E, Di Bartolomeo S, et al. In vitro antimicrobial susceptibility of Helicobacter pylori to nine antibiotics currently used in Central Italy. Scand J Gastroenterol. 2016;51(3):263–269. doi:10.3109/00365521.2015.109257726554617
   PubMed Web of Science ®Google Scholar
• Butlop T, Mungkote N, Chaichanawongsaroj N. Analysis of allelic variants of rdxA associated with metronidazole resistance in Helicobacter pylori: detection of common genotypes in rdxA by multiplex allele-specific polymerase chain reaction. Genet Mol Res. 2016;15(3). doi:10.4238/gmr.15038674
   Web of Science ®Google Scholar
• De Francesco V, Margiotta M, Zullo A, et al. Clarithromycin-resistant genotypes and eradication of Helicobacter pylori. Ann Intern Med. 2006;144(2):94–100. doi:10.7326/0003-4819-144-2-200601170-0000616418408
   PubMed Web of Science ®Google Scholar
• Fujimura S, Kato S, Iinuma K, Watanabe A. In vitro activity of fluoroquinolone and the gyrA gene mutation in Helicobacter pylori strains isolated from children. J Med Microbiol. 2004;53(10):1019–1022. doi:10.1099/jmm.0.45642-015358825
   PubMed Web of Science ®Google Scholar