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Original Research

Cryptococcus neoformans/gattii Species Complexes from Pre-HIV Pandemic Era Contain Unusually High Rate of Non-Wild-Type Isolates for Amphotericin B

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Pages 673-681 | Published online: 26 Feb 2020

References

  • Rajasingham R, Rolfes MA, Birkenkamp KE, Meya DB, Boulware DR. Cryptococcal meningitis treatment strategies in resource-limited settings: a cost-effectiveness analysis. PLoS Med. 2012;9:e1001316. doi:10.1371/journal.pmed.100131623055838
  • WHO. Guidelines for the Diagnosis, Prevention and Management of Cryptococcal Disease in HIV-Infected Adults, Adolescents and Children: Supplement to the 2016 Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection. Geneva, Switzerland: World Health Organization; 2018.
  • Brown GD, Denning DW, Gow NA, Levitz SM, Netea MG, White TC. Hidden killers: human fungal infections. Sci Transl Med. 2012;4:165rv113. doi:10.1126/scitranslmed.3004404
  • Mwaba P, Mwansa J, Chintu C, et al. Clinical presentation, natural history, and cumulative death rates of 230 adults with primary cryptococcal meningitis in Zambian AIDS patients treated under local conditions. Postgrad Med J. 2001;77:769–773. doi:10.1136/pmj.77.914.76911723315
  • Perfect JR, Cox GM. Drug resistance in Cryptococcus neoformans. Drug Resist Updat. 1999;2:259–269. doi:10.1054/drup.1999.009011504497
  • Perfect JR, Dismukes WE, Dromer F, et al. Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of america. Clin Infect Dis. 2010;50:291–322. doi:10.1086/64985820047480
  • Bongomin F, Oladele RO, Gago S, Moore CB, Richardson MD. A systematic review of fluconazole resistance in clinical isolates of Cryptococcus species. Mycoses. 2018;61:290–297. doi:10.1111/myc.1274729377368
  • Pappas PG. Antifungal trials: progress, approaches, new targets, and perspectives in cryptococcosis In: Heitman J, Kozel T, Kwon-Chung K, Perfect J, editors. Cryptococcus from Human Pathogen to Model Yeast. Washington (DC): American Society of Microbiology; 2011:527–536.
  • Mlinaric-Missoni E, Hagen F, Chew WH, Vazic-Babic V, Boekhout T, Begovac J. In vitro antifungal susceptibilities and molecular typing of sequentially isolated clinical Cryptococcus neoformans strains from Croatia. J Med Microbiol. 2011;60:1487–1495. doi:10.1099/jmm.0.031344-021617022
  • Chandenier J, Adou-Bryn KD, Douchet C, et al. In vitro activity of amphotericin B, fluconazole and voriconazole against 162 Cryptococcus neoformans isolates from Africa and Cambodia. Eur J Clin Microbiol Infect Dis. 2004;23:506–508. doi:10.1007/s10096-004-1136-215141336
  • Datta K, Jain N, Sethi S, Rattan A, Casadevall A, Banerjee U. Fluconazole and itraconazole susceptibility of clinical isolates of Cryptococcus neoformans at a tertiary care centre in India: a need for care. J Antimicrob Chemother. 2003;52:683–686. doi:10.1093/jac/dkg39912951350
  • Chen YC, Chang TY, Liu JW, et al. Increasing trend of fluconazole-non-susceptible Cryptococcus neoformans in patients with invasive cryptococcosis: a 12-year longitudinal study. BMC Infect Dis. 2015;15:277. doi:10.1186/s12879-015-1023-826194004
  • Soogarun S, Wiwanitkit V, Palasuwan A, et al. Detection of Cryptococcus neoformans in bird excreta. Southeast Asian J Trop Med Public Health. 2006;37:768–770.17121304
  • Hagen F, Khayhan K, Theelen B, et al. Recognition of seven species in the Cryptococcus gattii/Cryptococcus neoformans species complex. Fungal Genet Biol. 2015;78:16–48. doi:10.1016/j.fgb.2015.02.00925721988
  • Lockhart SR, Iqbal N, Bolden CB, et al. Epidemiologic cutoff values for triazole drugs in Cryptococcus gattii: correlation of molecular type and in vitro susceptibility. Diagn Microbiol Infect Dis. 2012;73:144–148. doi:10.1016/j.diagmicrobio.2012.02.01822494557
  • Tay ST, Tanty Haryanty T, Ng KP, Rohani MY, Hamimah H. In vitro susceptibilities of Malaysian clinical isolates of Cryptococcus neoformans var. grubii and Cryptococcus gattii to five antifungal drugs. Mycoses. 2006;49:324–330. doi:10.1111/j.1439-0507.2006.01242.x16784448
  • Andrade-Silva L, Ferreira-Paim K, Mora DJ, et al. Susceptibility profile of clinical and environmental isolates of Cryptococcus neoformans and Cryptococcus gattii in Uberaba, Minas Gerais, Brazil. Med Mycol. 2013;51:635–640. doi:10.3109/13693786.2012.76173723343452
  • CLSI. Epidemiological Cutoff Values for Antifungal Susceptibility Testing, CLSI Suppl M59 Document. 2nd ed. Wayne (PA): Clinical and Laboratory Standards Institute; 2018.
  • Danesi P, Firacative C, Cogliati M, Otranto D, Capelli G, Meyer W. Multilocus sequence typing (MLST) and M13 PCR fingerprinting revealed heterogeneity amongst Cryptococcus species obtained from Italian veterinary isolates. FEMS Yeast Res. 2014;14:897–909. doi:10.1111/1567-1364.1217824981157
  • CLSI. Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts, 4th Suppl., M27-S4. Wayne (PA): Clinical Laboratory Standards Institute; 2012.
  • Bennett JE. Susceptibility of Cryptococcus neoformans to amphotericin B. Antimicrob Agents Chemother (Bethesda). 1966;6:405–410.5985264
  • Meyer W, Aanensen DM, Boekhout T, et al. Consensus multi-locus sequence typing scheme for Cryptococcus neoformans and Cryptococcus gattii. Med Mycol. 2009;47:561–570. doi:10.1080/1369378090295388619462334
  • Meyer W, Castaneda A, Jackson S, Huynh M, Castaneda E, IberoAmerican Cryptococcal Study G. Molecular typing of IberoAmerican Cryptococcus neoformans isolates. Emerg Infect Dis. 2003;9:189–195. doi:10.3201/eid0902.02024612603989
  • Rex JH, Pfaller MA, Walsh TJ, et al. Antifungal susceptibility testing: practical aspects and current challenges. Clin Microbiol Rev. 2001;14:643–658. doi:10.1128/cmr.14.4.643-658.200111585779
  • Aller AI, Martin-Mazuelos E, Lozano F, et al. Correlation of fluconazole MICs with clinical outcome in cryptococcal infection. Antimicrob Agents Chemother. 2000;44:1544–1548. doi:10.1128/aac.44.6.1544-1548.200010817706
  • Pierard GE, Arrese JE, Pierard-Franchimont C. Itraconazole. Expert Opin Pharmacother. 2000;1:287–304. doi:10.1517/14656566.1.2.28711249550
  • Pan W, Khayhan K, Hagen F, et al. Resistance of Asian Cryptococcus neoformans serotype A is confined to few microsatellite genotypes. PLoS One. 2012;7:e32868. doi:10.1371/journal.pone.003286822427900
  • Hagen F, Hare Jensen R, Meis JF, Arendrup MC. Molecular epidemiology and in vitro antifungal susceptibility testing of 108 clinical Cryptococcus neoformans sensu lato and Cryptococcus gattii sensu lato isolates from Denmark. Mycoses. 2016;59:576–584. doi:10.1111/myc.1250727061834
  • Worasilchai N, Tangwattanachuleeporn M, Meesilpavikkai K, et al. Diversity and antifungal drug susceptibility of cryptococcus isolates in Thailand. Med Mycol. 2017;55:680–685. doi:10.1093/mmy/myw13027915307
  • Chowdhary A, Randhawa HS, Sundar G, et al. In vitro antifungal susceptibility profiles and genotypes of 308 clinical and environmental isolates of Cryptococcus neoformans var. grubii and Cryptococcus gattii serotype B from north-western India. J Med Microbiol. 2011;60:961–967. doi:10.1099/jmm.0.029025-021393452
  • Pfaller M, Zhang J, Messer S, et al. Molecular epidemiology and antifungal susceptibility of Cryptococcus neoformans isolates from Ugandan AIDS patients. Diagn Microbiol Infect Dis. 1998;32:191–199. doi:10.1016/S0732-8893(98)00095-99884835
  • Franzot SP, Hamdan JS. In vitro susceptibilities of clinical and environmental isolates of Cryptococcus neoformans to five antifungal drugs. Antimicrob Agents Chemother. 1996;40:822–824. doi:10.1128/AAC.40.3.8228851624
  • Archibald LK, Tuohy MJ, Wilson DA, et al. Antifungal susceptibilities of Cryptococcus neoformans. Emerg Infect Dis. 2004;10:143–145. doi:10.3201/eid1001.02077915078612
  • Trilles L, Fernandez-Torres B, Lazera Mdos S, Wanke B, Guarro J. In vitro antifungal susceptibility of Cryptococcus gattii. J Clin Microbiol. 2004;42:4815–4817. doi:10.1128/jcm.42.10.4815-4817.200415472349
  • Chen YC, Chang SC, Shih CC, et al. Clinical features and in vitro susceptibilities of two varieties of Cryptococcus neoformans in Taiwan. Diagn Microbiol Infect Dis. 2000;36:175–183. doi:10.1016/S0732-8893(99)00137-610729660
  • Mitchell TG, Perfect JR. Cryptococcosis in the era of AIDS-100 years after the discovery of Cryptococcus neoformans. Clin Microbiol Rev. 1995;8:515–548. doi:10.1128/CMR.8.4.5158665468
  • Pfaller MA, Messer SA, Jones RN, Castanheira M. Antifungal susceptibilities of Candida, Cryptococcus neoformans and Aspergillus fumigatus from the Asia and Western Pacific region: data from the SENTRY antifungal surveillance program (2010-2012). J Antibiot (Tokyo). 2015;68:556–561. doi:10.1038/ja.2015.2925899126
  • Selb R, Fuchs V, Graf B, et al. Molecular typing and in vitro resistance of Cryptococcus neoformans clinical isolates obtained in Germany between 2011 and 2017. Int J Med Microbiol. 2019;309:151336. doi:10.1016/j.ijmm.2019.15133631444102
  • Espinel-Ingroff A, Chowdhary A, Cuenca-Estrella M, et al. Cryptococcus neoformans-Cryptococcus gattii species complex: an international study of wild-type susceptibility endpoint distributions and epidemiological cutoff values for amphotericin B and flucytosine. Antimicrob Agents Chemother. 2012;56:3107–3113. doi:10.1128/AAC.06252-1122391546
  • O’Shaughnessy EM, Lyman CA, Walsh TJ. Amphotericin B: polyene resistance mechanisms In: Mayers DL, editor. Antimicrobial Drug Resistance: Mechanisms of Drug Resistance. Totowa, NJ: Humana Press; 2009:295–305.
  • Herkert PF, Meis JF, Lucca de Oliveira Salvador G, et al. Molecular characterization and antifungal susceptibility testing of Cryptococcus neoformans sensu stricto from southern Brazil. J Med Microbiol. 2018;67:560–569. doi:10.1099/jmm.0.00069829461182
  • Espinel-Ingroff A, Aller AI, Canton E, et al. Cryptococcus neoformans-Cryptococcus gattii species complex: an international study of wild-type susceptibility endpoint distributions and epidemiological cutoff values for fluconazole, itraconazole, posaconazole, and voriconazole. Antimicrob Agents Chemother. 2012;56:5898–5906. doi:10.1128/aac.01115-1222948877
  • Chong HS, Dagg R, Malik R, Chen S, Carter D. In vitro susceptibility of the yeast pathogen cryptococcus to fluconazole and other azoles varies with molecular genotype. J Clin Microbiol. 2010;48:4115–4120. doi:10.1128/jcm.01271-1020844209
  • Iqbal N, DeBess EE, Wohrle R, et al. Correlation of genotype and in vitro susceptibilities of Cryptococcus gattii strains from the Pacific Northwest of the United States. J Clin Microbiol. 2010;48:539–544. doi:10.1128/jcm.01505-0920007380