Mutations in the Antibiotic Target Genes Related to Clarithromycin, Metronidazole and Levofloxacin Resistance in Helicobacter pylori Strains from Children in China

References

• Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet. 1984;1:1311–1315. doi:10.1016/s0140-6736(84)91816-66145023
   PubMed Web of Science ®Google Scholar
• McColl KE. Clinical practice. helicobacter pylori infection. N Engl J Med. 2010;362:1597–1604. doi:10.1056/NEJMcp100111020427808
   PubMed Web of Science ®Google Scholar
• Francois F, Blaser MJ. Improving helicobacter pylori eradication regimens. Ann Intern Med. 2006;144:140–141. doi:10.7326/0003-4819-144-2-200601170-0001316418415
   PubMed Web of Science ®Google Scholar
• Brown LM. Helicobacter pylori: epidemiology and routes of transmission. Epidemiol Rev. 2000;22:283–297. doi:10.1093/oxfordjournals.epirev.a01804011218379
   PubMed Web of Science ®Google Scholar
• Xiang L, Zhu X, Huang D, Meng L, Wang L. Analysis on infection and drug resistance of helicobacter pylori in patients with gastric diseases. Chin J Nosocomiol. 2015;25:1710–1711.
   Google Scholar
• Bayerdorffer E, Neubauer A, Rudolph B, et al. Regression of primary gastric lymphoma of mucosa-associated lymphoid tissue type after cure of helicobacter pylori infection. MALT lymphoma study group. Lancet. 1995;345:1591–1594. doi:10.1016/s0140-6736(95)90113-27783535
   PubMed Web of Science ®Google Scholar
• Zhang YX, Zhou LY, Song ZQ, Zhang JZ, He LH, Ding Y. Primary antibiotic resistance of helicobacter pylori strains isolated from patients with dyspeptic symptoms in Beijing: a prospective serial study. World J Gastroenterol. 2015;21:2786–2792. doi:10.3748/wjg.v21.i9.278625759550
   PubMed Web of Science ®Google Scholar
• Shu X, Yin G, Liu M, Peng K, Zhao H, Jiang M. Antibiotics resistance of helicobacter pylori in children with upper gastrointestinal symptoms in Hangzhou, China. Helicobacter. 2018;23(3):e12481. doi:10.1111/hel.1248129528162
   PubMed Web of Science ®Google Scholar
• Megraud F, Lehours P. Helicobacter pylori detection and antimicrobial susceptibility testing. Clin Microbiol Rev. 2007;20:280–322. doi:10.1128/cmr.00033-0617428887
   PubMed Web of Science ®Google Scholar
• Megraud F, Benejat L, Ontsira Ngoyi EN, Lehours P. Molecular approaches to identify helicobacter pylori antimicrobial resistance. Gastroenterol Clin North Am. 2015;44:577–596. doi:10.1016/j.gtc.2015.05.00226314669
   PubMed Web of Science ®Google Scholar
• Thung I, Aramin H, Vavinskaya V, et al. Review article: the global emergence of helicobacter pylori antibiotic resistance. Aliment Pharmacol Ther. 2016;43:514–533. doi:10.1111/apt.1362526694080
   PubMed Web of Science ®Google Scholar
• Matteo MJ, Perez CV, Domingo MR, Olmos M, Sanchez C, Catalano M. DNA sequence analysis of rdxA and frxA from paired metronidazole-sensitive and -resistant helicobacter pylori isolates obtained from patients with heteroresistance. Int J Antimicrob Agents. 2006;27:152–158. doi:10.1016/j.ijantimicag.2005.09.01916426819
   PubMed Web of Science ®Google Scholar
• Tu IF, Liao JH, Yang FL, Lin NT, Chan HL, Wu SH. Lon protease affects the RdxA nitroreductase activity and metronidazole susceptibility in helicobacter pylori. Helicobacter. 2014;19:356–366. doi:10.1111/hel.1214024834789
   PubMed Web of Science ®Google Scholar
• Lee JW, Kim N, Nam RH, et al. Mutations of helicobacter pylori associated with fluoroquinolone resistance in Korea. Helicobacter. 2011;16:301–310. doi:10.1111/j.1523-5378.2011.00840.x21762270
   PubMed Web of Science ®Google Scholar
• Garcia M, Raymond J, Garnier M, Cremniter J, Burucoa C. Distribution of spontaneous gyrA mutations in 97 fluoroquinolone-resistant helicobacter pylori isolates collected in France. Antimicrob Agents Chemother. 2012;56:550–551. doi:10.1128/aac.05243-1122064536
   PubMed Web of Science ®Google Scholar
• Rimbara E, Noguchi N, Kawai T, Sasatsu M. Fluoroquinolone resistance in helicobacter pylori: role of mutations at position 87 and 91 of GyrA on the level of resistance and identification of a resistance conferring mutation in Gyr B. Helicobacter. 2012;17:36–42. doi:10.1111/j.1523-5378.2011.00912.x
   PubMed Web of Science ®Google Scholar
• Su P, Li Y, Li H, et al. Antibiotic resistance of helicobacter pylori isolated in the Southeast Coastal Region of China. Helicobacter. 2013;18:274–279. doi:10.1111/hel.1204623418857
   PubMed Web of Science ®Google Scholar
• Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing: Seventeenth Informational Supplement M100-S17. Wayne, PA, USA: CLSI; 2007.
   Google Scholar
• Ribeiro ML, Vitiello L, Miranda MC, et al. Mutations in the 23S rRNA gene are associated with clarithromycin resistance in helicobacter pylori isolates in Brazil. Ann Clin Microbiol Antimicrob. 2003;2:11. doi:10.1186/1476-0711-2-1114633281
   PubMedGoogle Scholar
• Marais A, Bilardi C, Cantet F, Mendz GL, Mégraud F. Characterization of the genes rdxA and frxA involved in metronidazole resistance in helicobacter pylori. Res Microbiol. 2003;154:137–144. doi:10.1016/s0923-2508(03)00030-512648728
   PubMed Web of Science ®Google Scholar
• Wang LH, Cheng H, Hu FL, Li J. Distribution of gyrA mutations in fluoroquinolone-resistant helicobacter pylori strains. World J Gastroenterol. 2010;16:2272–2277. doi:10.3748/wjg.v16.i18.227220458765
   PubMed Web of Science ®Google Scholar
• Chen J, Ye L, Jin L, et al. Application of next-generation sequencing to characterize novel mutations in clarithromycin-susceptible helicobacter pylori strains with A2143G of 23S rRNA gene. Ann Clin Microbiol Antimicrob. 2018;17:10. doi:10.1186/s12941-018-0259-829562911
   PubMed Web of Science ®Google Scholar
• Zhang J, Zhong J, Ding J, et al. Simultaneous detection of human CYP2C19 polymorphisms and antibiotic resistance of helicobacter pylori using a personalized diagnosis kit. J Glob Antimicrob Resist. 2018;13:174–179. doi:10.1016/j.jgar.2017.12.01829444465
   PubMed Web of Science ®Google Scholar
• Mahmoudi S, Mamishi S, Banar M, et al. Antibiotic susceptibility of helicobacter pylori strains isolated from Iranian children: high frequency of A2143G point mutation associated with clarithromycin resistance. J Glob Antimicrob Resist. 2017;10:131–135. doi:10.1016/j.jgar.2017.04.01128720314
   PubMed Web of Science ®Google Scholar
• Binkowska A, Biernat MM, Kaczmariski K, Gosciniak G. Molecular patterns of resistance among helicobacter pylori strains in South-Western Poland. Front Microbiol. 2018. doi:10.3389/fmicb.2018.03154
   Web of Science ®Google Scholar
• Quek C, Pham ST, Tran KT, et al. Antimicrobial susceptibility and clarithromycin resistance patterns of helicobacter pylori clinical isolates in Vietnam. F1000Research. 2016;5:671. doi:10.12688/f1000research.8239.127583131
   PubMedGoogle Scholar
• Cagan-Appak Y, Gazi H, Ayhan S, Cengiz-Ozyurt B, Kurutepe S, Kasirga E. Clarithromycin resistance and 23S rRNA gene point mutations of helicobacter pylori infection in children. Turk J Pediatr. 2016;58:371–376. doi:10.24953/turkjped.2016.04.00428276208
   PubMed Web of Science ®Google Scholar
• De Francesco V, Margiotta M, Zullo A, et al. Clarithromycin-resistant genotypes and eradication of helicobacter pylori. Ann Intern Med. 2006;144:94–100. doi:10.1016/j.jpeds.2010.02.00716418408
   PubMed Web of Science ®Google Scholar
• Phan TN, Santona A, Tran VH, et al. High rate of levofloxacin resistance in h background of clarithromycin and metronidazole-resistant helicobacter pylori in vietnam. Inter J Antimicrob Agents. 2015;45:244–248. doi:10.1016/j.ijantimicag.2014.10.019
   PubMed Web of Science ®Google Scholar
• Jaka H, Rhee JA, Ostlundh L, et al. The magnitude of antibiotic resistance of helicobacter pylori in Africa and identified mutations which confer resistance to antibiotics: a systematic review and meta-analysis. BMC Infect Dis. 2018;18:193. doi:10.1186/s12879-018-3099-429699490
   PubMed Web of Science ®Google Scholar
• Ieradi E, Giorgio F, Lousurdo G, Di Leo A, Principi M. How antibiotic resistances could change helicobacter pylori treatment: A matter of geography? World J Gastroenterol. 2013;19:8168–8180. doi:10.3748/wjg.v19.i45.816824363506
   PubMed Web of Science ®Google Scholar
• Kim KS, Kang JO, Eun CS, Han DS, Choi TY. Mutations in the 23S rRNA gene of helicobacter pylori associated with clarithromycin resistance. J Korean Med Sci. 2002;17:599–603. doi:10.3346/jkms.2002.17.5.59912378008
   PubMed Web of Science ®Google Scholar
• Fock KM, Ang TL. Epidemiology of helicobacter pylori infection and gastric cancer in Asia. J Gastroenterol Hepatol. 2010;25:479–486. doi:10.1111/j.1440-1746.2009.06188.x20370726
   PubMed Web of Science ®Google Scholar
• Luo Z, Zhang S, Sun Z, et al. Study on relationship between drug resistance of helicobacter pylori to metronidazole and rdx A genotype and cagA gene. Chin Hosp Pharm J. 2015;35:689–694. doi:10.1016/j.jms.2008.06.014
   Web of Science ®Google Scholar
• Mirzaei N, Poursina F, Moghim S, Rahimi E, Safaei HG. The mutation of the rdxA gene in metronidazole-resistant helicobacter pylori clinical isolates. Adv Biomed Res. 2014;3:90. doi:10.4103/2277-9175.12846924761398
   PubMedGoogle Scholar
• Tanih NF, Ndip LM, Ndip RN. Characterisation of the genes encoding resistance to metronidazole (rdxA and frxA) and clarithromycin (the 23S-rRNA genes) in South African isolates of helicobacter pylori. Ann Trop Med Parasitol. 2011;105:251–259. doi:10.1179/136485911X1289983868348521801504
   PubMed Web of Science ®Google Scholar
• Miyachi H, Miki I, Aoyama N, et al. Primary levofloxacin resistance and gyrA/B mutations among helicobacter pylori in Japan. Helicobacter. 2006;11:243–249. doi:10.1111/j.1523-5378.2006.00415.x16882327
   PubMed Web of Science ®Google Scholar
• Chisholm SA, Owen RJ. Frequency and molecular characteristics of ciprofloxacin-and rifampicin-resistant helicobacter pylori from gastric infections in the UK. J Med Microbiol. 2009;58:1322–1328. doi:10.1099/jmm.0.011270-019589906
   PubMed Web of Science ®Google Scholar
• Tankovic J, Lascols C, Sculo Q, Petit JC, Soussy CJ. Single and double mutations in gyrA but not in gyrB are associated with low-and high-level fluoroquinolone resistance in helicobacter pylori. Antimicrob Agents Chemother. 2003;47:3942–3944. doi:10.1128/AAC.47.12.3942-3944.200314638505
   PubMed Web of Science ®Google Scholar
• De Palma GZ, Mendiondo N, Wonaga A, et al. Occurrence of mutations in the antimicrobial target genes related to levofloxacin, clarithromycin, and amoxicillin resistance in helicobacter pylori isolates from Buenos Aires city. Microb Drug Resist. 2016;23:351–358. doi:10.1089/mdr.2015.036127391421
   PubMed Web of Science ®Google Scholar
• Miftahussurur M, Shrestha PK, Subsomwong P, Sharma RP, Yamaoka Y. Emerging helicobacter pylori levofloxacin resistance and novel genetic mutation in Nepal. BMC Microbiol. 2016;16:256. doi:10.1186/s12866-016-0873-627809767
   PubMed Web of Science ®Google Scholar