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Infection and Drug Resistance Volume 13, 2020 - Issue
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Case Report

Successful Treatment of a Multidrug-Resistant Tuberculosis Patient with a Negative Xpert MTB/RIF Test for Rifampicin-Resistant Tuberculosis in Guizhou Province of China: A Case Report

Zhao-Liang Zhao1 Tuberculosis Division of Respiratory and Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou563003, People’s Republic of China
,
Ling Chen1 Tuberculosis Division of Respiratory and Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou563003, People’s Republic of ChinaCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0002-2999-9255
ORCID Icon &
Hong Zhang1 Tuberculosis Division of Respiratory and Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou563003, People’s Republic of China;2 Z-BioMed, Inc., Rockville, MD20855, USAORCID Iconhttps://orcid.org/0000-0002-3930-6731
ORCID Icon
Pages 1351-1355 | Published online: 08 May 2020

References

  • World Health Organization. Global Tuberculosis Report 2019. Geneva: World Health Organization; 2019 Licence: CCBY-NC-SA3.0IGO.
  • Torrea G, Ng KCS, Van Deun A, et al. Variable ability of rapid tests to detect Mycobacterium tuberculosis rpoB mutations conferring phenotypically occult rifampicin resistance. Sci Rep. 2019;9(1):11826. doi:10.1038/s41598-019-48401-z31413308
  • World Health Organization. WHO treatment guidelines for drug-resistant tuberculosis. Geneva, Switzerland; 2016 Available from: http://apps.who.int/medicinedocs/en/d/Js23097en/. Accessed 15, 2020.
  • van Soolingen D, Hermans PW, de Haas PE, Soll DR, van Embden JD. Occurrence and stability of insertion sequences in Mycobacterium tuberculosis complex strains: evaluation of an insertion sequence-dependent DNA polymorphism as a tool in the epidemiology of tuberculosis. J Clin Microbiol. 1991;29(11):2578–2586.1685494
  • Andre E, Goeminne L, Cabibbe A, et al. Consensus numbering system for the rifampicin resistance-associated rpoB gene mutations in pathogenic mycobacteria. Clin Microbiol Infect. 2017;23(3):167–172. doi:10.1016/j.cmi.2016.09.00627664776
  • Zaw MT, Emran NA, Lin Z. Mutations inside rifampicin-resistance determining region of rpoB gene associated with rifampicin-resistance in Mycobacterium tuberculosis. J Infect Public Health. 2018;11(5):605–610. doi:10.1016/j.jiph.2018.04.00529706316
  • Siu GK, Zhang Y, Lau TC, et al. Mutations outside the rifampicin resistance-determining region associated with rifampicin resistance in Mycobacterium tuberculosis. J Antimicrob Chemother. 2011;66(4):730–733. doi:10.1093/jac/dkq51921393153
  • Chen L, Gan X, Li NN, et al. rpoB gene mutation profile in rifampicin-resistant Mycobacterium tuberculosis clinical isolates from Guizhou, one of the highest incidence rate regions in China. J Antimicrob Chemother. 2010;65(6):1299–1301. doi:10.1093/jac/dkq10220356906
  • André E, Goeminne L, Colmant A, Beckert P, Niemann S, Delmee M. Novel rapid PCR for the detection of Ile491Phe rpoB mutation of Mycobacterium tuberculosis, a rifampicin-resistance-conferring mutation undetected by commercial assays. Clin Microbiol Infect. 2017;23(4):267.e5–267.e7. doi:10.1016/j.cmi.2016.12.009
  • Al-Mutairi NM, Ahmad S, Mokaddas E, Eldeen HS, Joseph S. Occurrence of disputed rpoB mutations among Mycobacterium tuberculosis isolates phenotypically susceptible to rifampicin in a country with a low incidence of multidrug-resistant tuberculosis. BMC Infect Dis. 2019;19(1):3. doi:10.1186/s12879-018-3638-z30606116
  • Yuen LK, Leslie D, Coloe PJ. Bacteriological and molecular analysis of rifampin-resistant Mycobacterium tuberculosis strains isolated in Australia. J Clin Microbiol. 1999;37(12):3844–3850. doi:10.1128/JCM.37.12.3844-3850.199910565894
  • Javed H, Bakuła Z, Pleń M, et al. Evaluation of genotype MTBDRplus and MTBDRsl assays for rapid detection of drug resistance in extensively drug-resistant Mycobacterium tuberculosis isolates in Pakistan. Front Microbiol. 2018;9:2265. doi:10.3389/fmicb.2018.0226530319577

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