Multidrug-Resistant Acinetobacter baumannii – The Modern Menace: A Retrospective Study in a Tertiary Hospital in Mangalore

References

• Ventola CL. The antibiotic resistance crisis: part 1: causes and threats. Pharm Ther. 2015;40(4):277.
   Google Scholar
• Schwartz RS. Paul Ehrlich’s magic bullets. N Engl J Med. 2004;350(11):1079–1080. doi:10.1056/NEJMp04802115014180
   PubMed Web of Science ®Google Scholar
• Peleg AY, Seifert H, Paterson DL. Acinetobacter baumannii: the emergence of a successful pathogen. Clin Microbiol Rev. 2008;21(3):538–582.18625687
   PubMed Web of Science ®Google Scholar
• Howard A, O’dounoghue M, Feeney A, Sleeator RD. Acinetobacter baumannii: an emerging opportunistic pathogen. Virulence. 2012;3(3):243–250. doi:10.4161/viru.1970022546906
   PubMed Web of Science ®Google Scholar
• Asif M, Alvi IA, Rehman SU. Insight into Acinetobacter baumannii: pathogenesis, global resistance, mechanisms of resistance, treatment options, and alternative modalities. Infect Drug Resist. 2018;11:1249. doi:10.2147/IDR.S16675030174448
   PubMed Web of Science ®Google Scholar
• Al Atrouni A, Joly-Guillou ML, Hamze M, Kempf M. Reservoirs of non-baumannii Acinetobacter species. Front Microbiol. 2016;7:49. doi:10.3389/fmicb.2016.0004926870013
   PubMed Web of Science ®Google Scholar
• Fernández L, Hancock RE. Adaptive and mutational resistance: role of porins and efflux pumps in drug resistance. Clin Microbiol Rev. 2012;25(4):661–681. doi:10.1128/CMR.00043-1223034325
   PubMed Web of Science ®Google Scholar
• Alsan M, Klompas M. Acinetobacter baumannii: an emerging and important pathogen. J Clin Outcomes Manag. 2010;17(8):363.26966345
   PubMedGoogle Scholar
• Manchanda V, Sanchaita S, Singh NP. Multidrug resistant acinetobacter. J Glob Infect Dis. 2010;2(3):291. doi:10.4103/0974-777X.6853820927292
   PubMedGoogle Scholar
• Bergogne-Berezin E, Towner KJ. Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological features. Clin Microbiol Rev. 1996;9(2):148. doi:10.1128/CMR.9.2.1488964033
   PubMed Web of Science ®Google Scholar
• Rello J, Diaz E. Acinetobacter baumannii: a threat for the ICU? Intensive Care Med. 2003;29(3):350–351. doi:10.1007/s00134-003-1661-y12589534
   PubMed Web of Science ®Google Scholar
• Sileem AE, Said AM, Meleha MS. Acinetobacter baumannii in ICU patients: a prospective study highlighting their incidence, antibiotic sensitivity pattern and impact on ICU stay and mortality. Egypt J Chest Dis Tuberc. 2017;66(4):693–698. doi:10.1016/j.ejcdt.2017.01.003
   Web of Science ®Google Scholar
• Dent LL, Marshall DR, Pratap S, Hulette RB. Multidrug resistant Acinetobacter baumannii: a descriptive study in a city hospital. BMC Infect Dis. 2010;10:196. doi:10.1186/1471-2334-10-19620609238
   PubMed Web of Science ®Google Scholar
• Altun HU, Yagci S, Bulut C, et al. Antimicrobial susceptibilities of clinical Acinetobacter baumannii isolates with different genotypes. Jundishapur J Microbiol. 2014;7(12). doi:10.5812/jjm.13347
   Web of Science ®Google Scholar
• Eliopoulos GM, Maragakis LL, Perl TM. Acinetobacter baumannii: epidemiology, antimicrobial resistance, and treatment options. Clin Infect Dis. 2008;46(8):1254–1263. doi:10.1086/52919818444865
   PubMed Web of Science ®Google Scholar
• Ye JJ, Huang CT, Shie SS, et al. Multidrug resistant Acinetobacter baumannii: risk factors for appearance of imipenem resistant strains on patients formerly with susceptible strains. PLoS One. 2010;5(4):e9947. doi:10.1371/journal.pone.000994720369056
   PubMed Web of Science ®Google Scholar
• Blanco N, Harris AD, Rock C, et al. Risk factors and outcomes associated with multidrug-resistant Acinetobacter baumannii upon intensive care unit admission. Antimicrob Agents Chemother. 2018;62(1):e01631–17. doi:10.1128/AAC.01631-17
   Web of Science ®Google Scholar
• Abbo A, Carmeli Y, Navon-Venezia S, Siegman-Igra Y, Schwaber MJ. Impact of multi-drug-resistant Acinetobacter baumannii on clinical outcomes. Eur J Clin Microbiol Infect Dis. 2007;26(11):793–800. doi:10.1007/s10096-007-0371-817701063
   PubMed Web of Science ®Google Scholar
• Fillaux J, Dubouix A, Conil J-M, Laguerre J, Marty N. Retrospective analysis of multidrug-resistant acinetobacter baumannii strains isolated during a 4-year period in a University Hospital. Infect Control Hosp Epidemiol. 2006;27(7):647–653. doi:10.1086/50708216807836
   PubMed Web of Science ®Google Scholar
• Duszynska W, Litwin A, Rojek S, Szczesny A, Ciasullo A, Gozdzik W. Analysis of Acinetobacter baumannii hospital infections in patients treated at the intensive care unit of the University Hospital, Wroclaw, Poland: a 6-year, single-center, retrospective study. Infect Drug Resist. 2018;11:629. doi:10.2147/IDR.S16223229750043
   PubMed Web of Science ®Google Scholar
• Jung JY, Park MS, Kim SE, et al. Risk factors for multidrug resistant Acinetobacter baumannii bacteremia in patients with colonization in the intensive care unit. BMC Infect Dis. 2010;10(1):228. doi:10.1186/1471-2334-10-22820670453
   PubMed Web of Science ®Google Scholar
• Munier AL, Biard L, Rousseau C, et al. Incidence, risk factors, and outcome of multidrug-resistant Acinetobacter baumannii acquisition during an outbreak in a burns unit. J Hosp Inf. 2017;97(3):226–233. doi:10.1016/j.jhin.2017.07.020
   Web of Science ®Google Scholar
• Odsbu I, Khedkar S, Khedkar U, Nerkar SS, Tamhankar AJ, Stålsby Lundborg C. High proportions of multidrug-resistant Acinetobacter spp. isolates in a district in Western India: a four-year antibiotic susceptibility study of clinical isolates. Int J Environ Res Public Health. 2018;15(1):153. doi:10.3390/ijerph15010153
   Web of Science ®Google Scholar
• Khajuria A, Praharaj AK, Kumar M, Grover N. Molecular characterization of carbapenem resistant isolates of Acinetobacter baumannii in an intensive care unit of a tertiary care centre at central India. J Clin Diagn Res. 2014;8(5):DC38. doi:10.7860/JCDR/2014/6788.395624995182
   PubMedGoogle Scholar
• Sherwani N, Barapatre R, Neral A, Singh R, Gade N. A study of multidrug-resistant Acinetobacter baumannii – a susceptibility pattern and possible risk factors in a tertiary care hospital of Chattisgarh. J Evol Med Dent Sci. 2018;7(36):3935–3940. doi:10.14260/jemds/2018/880
   Web of Science ®Google Scholar
• Ruan Z, Feng Y. BacWGSTdb, a database for genotyping and source tracking bacterial pathogens. Nucleic Acids Res. 2016;44(D1):D682–D687. doi:10.1093/nar/gkv100426433226
   PubMed Web of Science ®Google Scholar