The Existence of High Bacterial Resistance to Some Reserved Antibiotics in Tertiary Hospitals in Tanzania: A Call to Revisit Their Use

References

• Levy SB, Marshall B. Antibacterial resistance worldwide: causes, challenges and responses. Nat Med. 2004;10(12):S122–S129. doi:10.1038/nm114515577930
   PubMed Web of Science ®Google Scholar
• Wormser GP, Bergman MM. The antibiotic paradox: how the misuse of antibiotics destroys their curative powers, 2nd Edition By Stuart B. Levy Cambridge, Massachusetts: perseus Publishing, 2002. 376 pp., illustrated. $17.50 (paper). Clin Infect Dis. 2003;36(2):238. doi:10.1086/344957
   Google Scholar
• Geneva. Prioritization of Pathogens to Guide Discovery, Research and Development of New Antibiotics for Drug-Resistant Bacterial Infections, Including Tuberculosis. World Health Organization; 2017:12.
   Google Scholar
• Hawkey PM, Warren RE, Livermore DM, et al. Treatment of infections caused by multidrug-resistant gram-negative bacteria: report of the British society for antimicrobial chemotherapy/healthcare infection society/british infection association joint working party. J Antimicrobial Chemother. 2018;73(2015):iii2–iii78. doi:10.1093/jac/dky027
   Web of Science ®Google Scholar
• Roope LSJ, Smith RD, Pouwels KB, et al. The challenge of antimicrobial resistance: what economics can contribute. Science. 2019;364:eaau4679. doi:10.1126/science.aau467930948524
   PubMed Web of Science ®Google Scholar
• Frieden T. Antibiotic resistance threats in the United States. Centers Dis Control Prev. 2013;114 doi:CS239559-B.
   Google Scholar
• Berthe F, Jean C, Wadsworth J, Thiebaud A, Marquez PV, Baris E. Pulling together to beat superbugs knowledge and implementation gaps in addressing antimicrobial resistance In: HNP/Agriculture Global Antimicrobial Resistance Initiative. Washington, DC: World Bank Group; 2019.15:16:04
   Google Scholar
• Cardoso T, Ribeiro O, Aragão IC, Costa-Pereira A, Sarmento AE. Additional risk factors for infection by multidrug-resistant pathogens in healthcare-associated infection: A large cohort study. BMC Infect Dis. 2012;12(1). doi:10.1186/1471-2334-12-375
   Web of Science ®Google Scholar
• Laxminarayan R, Matsoso P, Pant S, et al. Access to effective antimicrobials: a worldwide challenge. Lancet. 2016;387(10014):168–175. doi:10.1016/S0140-6736(15)00474-226603918
   PubMed Web of Science ®Google Scholar
• Payne LE, Gagnon DJ, Riker RR, et al. Cefepime-induced neurotoxicity: a systematic review. Crit Care. 2017;21(1):276. doi:10.1186/s13054-017-1856-129137682
   PubMed Web of Science ®Google Scholar
• WHO. World health organization model list of essential medicines. Mental and Holistic Health: Some International Perspectives; 2019:119–134.
   Google Scholar
• Ministry of Health and Social Welfare. Standard Treatment Guidelines & National Essential Medicines List, Tanzania Mainland; 2017.
   Google Scholar
• Lambert ML, Suetens C, Savey A, et al. Clinical outcomes of health-care-associated infections and antimicrobial resistance in patients admitted to European intensive-care units: A cohort study. Lancet Infect Dis. 2011;11(1):30–38. doi:10.1016/S1473-3099(10)70258-921126917
   PubMed Web of Science ®Google Scholar
• Mshana SE, Kamugisha E, Mirambo M, Chalya P, Rambau P, Mahalu W. Prevalence of clindamycin inducible resistance among methicillin-resistant Staphylococcus aureus at Bugando Medical Centre, Mwanza, Tanzania. Tanzania J Health Res. 2009;11(2):59–64.
   Google Scholar
• Mushi MF, Mshana SE, Imirzalioglu C, Bwanga F. Carbapenemase Genes among Multidrug Resistant Gram Negative Clinical Isolates from a Tertiary Hospital in Mwanza, Tanzania. BioMed Res Int. 2014;2014.
   Web of Science ®Google Scholar
• Organization WH. WHO model list of essential medicines. World Health Organization; 10, 2013:1–43. Available from: https://www.who.int/medicines/publications/essentialmedicines/en/.
   Google Scholar
• Moremi N, Claus H, Mshana SE. Antimicrobial resistance pattern: a report of microbiological cultures at a tertiary hospital in Tanzania. BMC Infect Dis. 2016;1–7. doi:10.1186/s12879-016-2082-126729246
   PubMed Web of Science ®Google Scholar
• Bartlett JG. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Infect Dis Clin Pract. 2004;12(6):376. doi:10.1097/01.idc.0000144912.27311.19
   Google Scholar
• Bai Y, Zheng Z, Du M, Yao H, Liu Y, Suo J. Bloodstream Infection and its clinical characteristics and relevant factors associated with interventional therapy in a large tertiary hospital: a six years surveillance study. Biomed Res Int. 2019;2019:1–7. doi:10.1155/2019/8190475
   Web of Science ®Google Scholar
• Mhada TV, Fredrick F, Matee MI, Massawe A. Neonatal sepsis at Muhimbili National Hospital, Dar es Salaam, Tanzania; aetiology, antimicrobial sensitivity pattern and clinical outcome. BMC Public Health. 2012;12(1):904. doi:10.1186/1471-2458-12-90423095365
   PubMed Web of Science ®Google Scholar
• Karchmer AW. Nosocomial bloodstream infections: organisms, risk factors, and implications. Clin Infect Dis. 2000;31(Supplement_4):S139–S143. doi:10.1086/31407811017863
   PubMed Web of Science ®Google Scholar
• Fokas S, Fokas S, Tsironi M, Kalkani M, Dionysopouloy M. Prevalence of inducible clindamycin resistance in macrolide-resistant Staphylococcus spp. Clin Microbiol Infect. 2005;11(4):337–340. doi:10.1111/j.1469-0691.2005.01101.x15760435
   PubMed Web of Science ®Google Scholar
• Odsbu I, Khedkar S, Lind F, et al. Trends in resistance to extended-spectrum cephalosporins and carbapenems among Escherichia coli and Klebsiella spp. Isolates in a district in Western India during 2004–2014. Int J Environ Res Public Health. 2018;15(1):1–15. doi:10.3390/ijerph15010155
   Web of Science ®Google Scholar
• Sattari-Maraji A, Jabalameli F, Node Farahani N, Beigverdi R, Emaneini M. Antimicrobial resistance pattern, virulence determinants and molecular analysis of Enterococcus faecium isolated from children infections in Iran. BMC Microbiol. 2019;19(1):156. doi:10.1186/s12866-019-1539-y31286887
   PubMed Web of Science ®Google Scholar
• Kristich CJ, Rice LB, Arias CA. Enterococcal infection — treatment and antibiotic resistance molecular mechanisms of antibiotic resistance in enterococci. 2014;1–31.
   Google Scholar
• Sonda TB, Horumpende PG, Kumburu HH, et al. Ceftriaxone use in a tertiary care hospital in Kilimanjaro, Tanzania: a need for a hospital antibiotic stewardship programme. PLoS One. 2019;14(8):1–11. doi:10.1371/journal.pone.0220261
   Web of Science ®Google Scholar
• Mboya EA, Sanga LA, Ngocho JS. Irrational use of antibiotics in the moshi municipality Northern Tanzania: a cross sectional study. Pan Afr Med J. 2018;31:1–10. doi:10.11604/pamj.2018.31.165.1599130918535
   PubMed Web of Science ®Google Scholar
• Edition TUR of TSTG and EMLM of H and SWF. The United Republic of Tanzania Standard Treatment Guidelines and Essential Medicines List Ministry of Health and Social Welfare Fourth Edition; 2013.
   Google Scholar
• Santajit S, Indrawattana N. Mechanisms of antimicrobial resistance in ESKAPE pathogens. Biomed Res Int. 2016;2016:1–8. doi:10.1155/2016/2475067
   Web of Science ®Google Scholar
• Wangai FK, Masika MM, Lule GN, et al. Bridging antimicrobial resistance knowledge gaps: the East African perspective on a global problem. PLoS One. 2019;14(2):1–12. doi:10.1371/journal.pone.0212131
   Web of Science ®Google Scholar
• Tadesse BT, Ashley EA, Ongarello S, et al. Antimicrobial resistance in Africa: a systematic review. BMC Infect Dis. 2017;17(1):1–17. doi:10.1186/s12879-017-2713-128049444
   PubMed Web of Science ®Google Scholar
• Ssekatawa K, Byarugaba DK, Wampande E, Ejobi F. A systematic review: the current status of carbapenem resistance in East Africa. BMC Res Notes. 2018;11(1):1–9. doi:10.1186/s13104-018-3738-229291749
   PubMedGoogle Scholar
• Yan K, Xue M, Ye D, et al. Antibiotic prescribing practices in secondary and tertiary hospitals in Shaanxi province, western China, 2013–2015. PLoS One. 2018;13(12):2013–2015. doi:10.1371/journal.pone.0207229
   Web of Science ®Google Scholar
• Sharma M, Eriksson B, Marrone G, Dhaneria S, Lundborg CS. Antibiotic prescribing in two private sector hospitals; one teaching and one non-teaching: A cross-sectional study in Ujjain, India. BMC Infect Dis. 2012;12(1). doi:10.1186/1471-2334-12-155
   Web of Science ®Google Scholar
• Landstedt K, Sharma A, Johansson F, Stålsby Lundborg C, Sharma M. Antibiotic prescriptions for inpatients having non-bacterial diagnosis at medicine departments of two private sector hospitals in Madhya Pradesh, India: a cross-sectional study. BMJ Open. 2017;7(4):e012974. doi:10.1136/bmjopen-2016-012974
   PubMed Web of Science ®Google Scholar
• Charan J, Biswas T. How to calculate sample size for different study designs in medical research? Indian J Psychol Med. 2013;35(2):121–126. doi:10.4103/0253-7176.11623224049221
   PubMedGoogle Scholar
• Collee JG, Miles RS, Watt B. (1996) Tests for the identification of bacteria In: Collee JG, Marmion BP, Fraser AG, Simmons A, editors. Mackie & McCartney Practical Medical Microbiology, 14th Edition, Churchill Livingstone, New York, 131–151.
   Google Scholar
• Şimşek S, Yurtseven N, Gerçekogalu H, et al. Ventilator-associated pneumonias in a cardiothoracic surgery centre postoperative intensive care unit. J Hosp Infect. 2001;47(4):321–324. doi:10.1053/jhin.2000.093211289777
   PubMed Web of Science ®Google Scholar
• CLSI. Performance Standards for Antimicrobial Disk Susceptibility Tests; Approved Standard—Twelfth Edition. CLSI document M02-A12. Wayne, PA: Clinical and Laboratory Standards Institute; 2015.
   Google Scholar