High Prevalence of 16S rRNA Methyltransferase Genes in Carbapenem-Resistant Klebsiella pneumoniae Clinical Isolates Associated with Bloodstream Infections in 11 Chinese Teaching Hospitals

References

• Gonzalez LS 3rd, Spencer JP. Aminoglycosides: a practical review. Am Family Phy. 1998;58(8):1811–1820.
   PubMed Web of Science ®Google Scholar
• Jiang M, Karasawa T, Steyger PS. Aminoglycoside induced cochleotoxicity: a review. Front Cell Neurosci. 2017;11:308.29062271
   PubMed Web of Science ®Google Scholar
• O’Sullivan ME, Perez A, Lin R, Sajjadi A, Ricci AJ, Cheng AG. Towards the prevention of aminoglycoside related hearing loss. Front Cell Neurosci. 2017;11:325. doi:10.3389/fncel.2017.0032529093664
   PubMed Web of Science ®Google Scholar
• Iovleva A, Doi Y. Carbapenem resistant enterobacteriaceae. Clin Lab Med. 2017;37(2):303–315. doi:10.1016/j.cll.2017.01.00528457352
   PubMed Web of Science ®Google Scholar
• Yamane K, Wachino J, Doi Y, Kurokawa H, Arakawa Y. Global spread of multiple aminoglycoside resistance genes. Emerging Infect Dis. 2005;11(6):951–953. doi:10.3201/eid1106.04092415963295
   PubMed Web of Science ®Google Scholar
• Doi Y, Arakawa Y. 16S ribosomal RNA methylation: emerging resistance mechanism against aminoglycosides. Clin Infect Dis. 2007;45(1):88–94. doi:10.1086/51860517554708
   PubMed Web of Science ®Google Scholar
• Kotra LP, Haddad J, Mobashery S. Aminoglycosides: perspectives on mechanisms of action and resistance and strategies to counter resistance. Antimicrob Agents Chemother. 2000;44(12):3249–3256. doi:10.1128/AAC.44.12.3249-3256.200011083623
   PubMed Web of Science ®Google Scholar
• Poole K. Aminoglycoside resistance in Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2005;49(2):479–487. doi:10.1128/AAC.49.2.479-487.200515673721
   PubMed Web of Science ®Google Scholar
• Ramirez MS, Tolmasky ME. Aminoglycoside modifying enzymes. Drug Res Updates. 2010;13(6):151–171. doi:10.1016/j.drup.2010.08.003
   PubMed Web of Science ®Google Scholar
• Galimand M, Courvalin P, Lambert T. Plasmid-mediated high-level resistance to aminoglycosides in enterobacteriaceae due to 16S rRNA methylation. Antimicrob Agents Chemother. 2003;47(8):2565–2571. doi:10.1128/AAC.47.8.2565-2571.200312878520
   PubMed Web of Science ®Google Scholar
• Doi Y, Wachino JI, Arakawa Y. Aminoglycoside resistance: the emergence of acquired 16S ribosomal RNA methyltransferases. Infectious Dis Clin North Am. 2016;30(2):523–537. doi:10.1016/j.idc.2016.02.01127208771
   PubMed Web of Science ®Google Scholar
• Bercot B, Poirel L, Nordmann P. Updated multiplex polymerase chain reaction for detection of 16S rRNA methylases: high prevalence among NDM-1 producers. Diagn Microbiol Infect Dis. 2011;71(4):442–445. doi:10.1016/j.diagmicrobio.2011.08.01622000158
   PubMed Web of Science ®Google Scholar
• CLSI. 2018 CLSI performance standards for antimicrobial susceptibility testing. 28th ed.CLSI supplement M100.Wayne. PA. 2018;2018:320.
   Google Scholar
• Wu Q, Zhang Y, Han L, Sun J, Ni Y. Plasmid-mediated 16S rRNA methylases in aminoglycoside-resistant enterobacteriaceae isolates in Shanghai, China. Antimicrob Agents Chemother. 2009;53(1):271–272. doi:10.1128/AAC.00748-0818955532
   PubMed Web of Science ®Google Scholar
• Taylor E, Sriskandan S, Woodford N, Hopkins KL. High prevalence of 16S rRNA methyltransferases among carbapenemase-producing enterobacteriaceae in the UK and Ireland. Int J Antimicrob Agents. 2018;52(2):278–282. doi:10.1016/j.ijantimicag.2018.03.01629596903
   PubMed Web of Science ®Google Scholar
• Bankevich A, Nurk S, Antipov D, et al. SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing. J Computational Biol. 2012;19(5):455–477. doi:10.1089/cmb.2012.0021
   PubMed Web of Science ®Google Scholar
• Zankari E, Hasman H, Cosentino S, et al. Identification of acquired antimicrobial resistance genes. J Antimicrob Chemother. 2012;67(11):2640–2644. doi:10.1093/jac/dks26122782487
   PubMed Web of Science ®Google Scholar
• Yu T, He T, Yao H, et al. Prevalence of 16S rRNA methylase gene rmtB among escherichia coli isolated from bovine mastitis in Ningxia, China. Foodborne Pathogens Dis. 2015;12(9):770–777. doi:10.1089/fpd.2015.1983
   Web of Science ®Google Scholar
• Diancourt L, Passet V, Verhoef J, Grimont PA, Brisse S. Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates. J Clin Microbiol. 2005;43(8):4178–4182. doi:10.1128/JCM.43.8.4178-4182.200516081970
   PubMed Web of Science ®Google Scholar
• Tenover FC, Arbeit RD, Goering RV, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol. 1995;33(9):2233–2239. doi:10.1128/JCM.33.9.2233-2239.19957494007
   PubMed Web of Science ®Google Scholar
• Nordmann P. Carbapenemase-producing enterobacteriaceae: overview of a major public health challenge. Med Mal Infect. 2014;44(2):51–56. doi:10.1016/j.medmal.2013.11.00724360201
   PubMed Web of Science ®Google Scholar
• Lee CR, Lee JH, Park KS, Kim YB, Jeong BC, Lee SH. Global dissemination of carbapenemase-producing klebsiella pneumoniae: epidemiology, genetic context, treatment options, and detection methods. Front Microbiol. 2016;7:895.27379038
   PubMed Web of Science ®Google Scholar
• Endimiani A, Depasquale JM, Forero S, et al. Emergence of blaKPC-containing Klebsiella pneumoniae in a long-term acute care hospital: a new challenge to our healthcare system. J Antimicrobial Chemother. 2009;64(5):1102–1110. doi:10.1093/jac/dkp327
   PubMed Web of Science ®Google Scholar
• Neuner EA, Yeh JY, Hall GS, et al. Treatment and outcomes in carbapenem-resistant Klebsiella pneumoniae bloodstream infections. Diagn Microbiol Infect Dis. 2011;69(4):357–362. doi:10.1016/j.diagmicrobio.2010.10.01321396529
   PubMed Web of Science ®Google Scholar
• Patel G, Huprikar S, Factor SH, Jenkins SG, Calfee DP. Outcomes of carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies. Infection Control Hospital Epidemiol. 2008;29(12):1099–1106. doi:10.1086/592412
   PubMed Web of Science ®Google Scholar
• Zhang Y, Wang Q, Yin Y, et al. Epidemiology of carbapenem-resistant enterobacteriaceae infections: report from the China CRE network. Antimicrob Agents Chemother. 2018;62:2.
   Web of Science ®Google Scholar
• Karaiskos I, Lagou S, Pontikis K, Rapti V, Poulakou G. The “old” and the “new” antibiotics for MDR gram-negative pathogens: for whom, when, and how. Front Public Health. 2019;7:151. doi:10.3389/fpubh.2019.0015131245348
   PubMed Web of Science ®Google Scholar
• Yu FY, Yao D, Pan JY, et al. High prevalence of plasmid-mediated 16S rRNA methylase gene rmtB among Escherichia coli clinical isolates from a Chinese teaching hospital. BMC Infect Dis. 2010;10:184. doi:10.1186/1471-2334-10-18420573216
   PubMed Web of Science ®Google Scholar
• Huang J, Deng S, Ren J, Tu J, Ye M, Wang M. Characterization of a blaNDM1harboring plasmid from a Salmonella enterica clinical isolate in China. Mol Med Rep. 2017;16(2):1087–1092. doi:10.3892/mmr.2017.673328627648
   PubMed Web of Science ®Google Scholar
• Galani I, Nafplioti K, Adamou P, Karaiskos I, Giamarellou H, Souli M. Nationwide epidemiology of carbapenem resistant Klebsiella pneumoniae isolates from Greek hospitals, with regards to plazomicin and aminoglycoside resistance. BMC Infect Dis. 2019;19(1):167. doi:10.1186/s12879-019-3801-130770727
   PubMed Web of Science ®Google Scholar
• Lin L, Xiao X, Wang X, Xia M, Liu S. In vitro antimicrobial susceptibility differences between carbapenem-resistant KPC-2-producing and NDM-1-producing Klebsiella pneumoniae in a teaching hospital in Northeast China. Microbial Drug Resist. 2019.
   Web of Science ®Google Scholar
• Yu F, Wang L, Pan J, et al. Prevalence of 16S rRNA methylase genes in Klebsiella pneumoniae isolates from a Chinese teaching hospital: coexistence of rmtB and armA genes in the same isolate. Diagn Microbiol Infect Dis. 2009;64(1):57–63. doi:10.1016/j.diagmicrobio.2009.01.02019232867
   PubMed Web of Science ®Google Scholar
• Yu X, Zhang W, Zhao Z, et al. Molecular characterization of carbapenem-resistant Klebsiella pneumoniae isolates with focus on antimicrobial resistance. BMC Genomics. 2019;20(1):822. doi:10.1186/s12864-019-6225-931699025
   PubMed Web of Science ®Google Scholar
• Zhang Y, Jin L, Ouyang P, et al. Evolution of hypervirulence in carbapenem-resistant Klebsiella pneumoniae in China: a multicentre, molecular epidemiological analysis. J Antimicrobial Chemother. 2019.
   Web of Science ®Google Scholar
• Zeng L, Deng Q, Zeng T, Liu Y, Zhang J, Cao X. Prevalence of carbapenem-resistant klebsiella pneumoniae infection in southern China: clinical characteristics, antimicrobial resistance, virulence, and geographic distribution. Microb Drug Resist. 2019.
   Web of Science ®Google Scholar
• Zhou K, Xiao T, David S, et al. Novel subclone of carbapenem-resistant Klebsiella pneumoniae sequence type 11 with enhanced virulence and transmissibility, China. Emerging Infect Dis. 2020;26(2):289–297. doi:10.3201/eid2602.19059431961299
   PubMed Web of Science ®Google Scholar