194
Views
7
CrossRef citations to date
0
Altmetric
Original Research

Pyrazinamide Resistance and Mutation Patterns Among Multidrug-Resistant Mycobacterium tuberculosis from Henan Province

, , , , , , & show all
Pages 2929-2941 | Published online: 20 Aug 2020

References

  • Diacon AH, Van Baelen B, Theeuwes M. More on treatment outcomes in multidrug-resistant tuberculosis. N Engl J Med. 2016;375(26):2609–2610.
  • Johnston JC, Shahidi NC, Sadatsafavi M, Fitzgerald JM. Treatment outcomes of multidrug-resistant tuberculosis: a systematic review and meta-analysis. PLoS One. 2009;4(9):e6914. doi:10.1371/journal.pone.000691419742330
  • Collaborative Group for the Meta-Analysis of Individual Patient Data in MDRTBt, Ahmad N, Ahuja SD, et al. Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis. Lancet. 2018;392(10150):821–834. doi:10.1016/S0140-6736(18)31644-1.30215381
  • Zhao Y, Xu S, Wang L, et al. National survey of drug-resistant tuberculosis in China. N Engl J Med. 2012;366(23):2161–2170. doi:10.1056/NEJMoa110878922670902
  • Gandhi NR, Nunn P, Dheda K, et al. Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis. Lancet. 2010;375(9728):1830–1843. doi:10.1016/S0140-6736(10)60410-220488523
  • Dheda K, Chang KC, Guglielmetti L, et al. Clinical management of adults and children with multidrug-resistant and extensively drug-resistant tuberculosis. Clin Microbiol Infect. 2017;23(3):131–140. doi:10.1016/j.cmi.2016.10.00827756712
  • Scorpio A, Lindholm-Levy P, Heifets L, et al. Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis. Antimicrob Agents Chemother. 1997;41(3):540–543. doi:10.1128/AAC.41.3.5409055989
  • Zhang Y, Shi W, Zhang W, Mitchison D. Mechanisms of pyrazinamide action and resistance. Microbiol Spect. 2014;2(4):MGM2-0023-2013. doi:10.1128/microbiolspec.MGM2-0023-2013
  • Mestdagh M, Fonteyne PA, Realini L, et al. Relationship between pyrazinamide resistance, loss of pyrazinamidase activity, and mutations in the pncA locus in multidrug-resistant clinical isolates of Mycobacterium tuberculosis. Antimicrob Agents Chemother. 1999;43(9):2317–2319. doi:10.1128/AAC.43.9.231710471589
  • Stoffels K, Mathys V, Fauville-Dufaux M, Wintjens R, Bifani P. Systematic analysis of pyrazinamide-resistant spontaneous mutants and clinical isolates of Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2012;56(10):5186–5193. doi:10.1128/AAC.05385-1122825123
  • Zhang S, Chen J, Shi W, Liu W, Zhang W, Zhang Y. Mutations in panD encoding aspartate decarboxylase are associated with pyrazinamide resistance in Mycobacterium tuberculosis. Emerg Microbes Infect. 2013;2(6):e34. doi:10.1038/emi.2013.3826038471
  • Huy NQ, Lucie C, Hoa TTT, et al. Molecular analysis of pyrazinamide resistance in Mycobacterium tuberculosis in Vietnam highlights the high rate of pyrazinamide resistance-associated mutations in clinical isolates. Emerg Microbes Infect. 2017;6(10):e86. doi:10.1038/emi.2017.7329018250
  • Shi W, Zhang X, Jiang X, et al. Pyrazinamide inhibits trans-translation in Mycobacterium tuberculosis. Science. 2011;333(6049):1630–1632. doi:10.1126/science.120881321835980
  • Zhang Y, Chiu Chang K, Leung CC, et al. ‘Z(S)-MDR-TB’ versus ‘Z(R)-MDR-TB’: improving treatment of MDR-TB by identifying pyrazinamide susceptibility. Emerg Microbes Infect. 2012;1(7):e5. doi:10.1038/emi.2012.1826038418
  • Tam KK, Leung KS, Siu GK, et al. Direct detection of pyrazinamide resistance in mycobacterium tuberculosis by use of pncA PCR sequencing. J Clin Microbiol. 2019;57:8. doi:10.1128/JCM.00145-19
  • Kurbatova EV, Cavanaugh JS, Dalton T, Click ES, Cegielski JP. Epidemiology of pyrazinamide-resistant tuberculosis in the United States, 1999-2009. Clin Infect Dis. 2013;57(8):1081–1093. doi:10.1093/cid/cit45223840002
  • Shi J, Zheng D, Zhu Y, et al. Role of MIRU-VNTR and spoligotyping in assessing the genetic diversity of Mycobacterium tuberculosis in Henan Province, China. BMC Infect Dis. 2018;18(1):447. doi:10.1186/s12879-018-3351-y30176820
  • Kamerbeek J, Schouls L, Kolk A, et al. Simultaneous detection and strain differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology. J Clin Microbiol. 1997;35(4):907–914. doi:10.1128/JCM.35.4.907-914.19979157152
  • Chen YY, Chang JR, Wu CD, et al. Combining molecular typing and spatial pattern analysis to identify areas of high tuberculosis transmission in a moderate-incidence county in Taiwan. Sci Rep. 2017;7(1):5394. doi:10.1038/s41598-017-05674-628710410
  • Mokrousov I, Ly HM, Otten T, et al. Origin and primary dispersal of the Mycobacterium tuberculosis Beijing genotype: clues from human phylogeography. Genome Res. 2005;15(10):1357–1364. doi:10.1101/gr.384060516169923
  • Dookie N, Rambaran S, Padayatchi N, Mahomed S, Naidoo K. Evolution of drug resistance in Mycobacterium tuberculosis: a review on the molecular determinants of resistance and implications for personalized care. J Antimicrob Chemother. 2018;73(5):1138–1151. doi:10.1093/jac/dkx50629360989
  • Zhang Y, Yew WW. Mechanisms of drug resistance in Mycobacterium tuberculosis: update 2015. Int J Tuberculosis Lung Dis. 2015;19(11):1276–1289. doi:10.5588/ijtld.15.0389
  • Pang Y, Zhu D, Zheng H, et al. Prevalence and molecular characterization of pyrazinamide resistance among multidrug-resistant Mycobacterium tuberculosis isolates from Southern China. BMC Infect Dis. 2017;17(1):711. doi:10.1186/s12879-017-2761-629110640
  • Gu Y, Yu X, Jiang G, et al. Pyrazinamide resistance among multidrug-resistant tuberculosis clinical isolates in a national referral center of China and its correlations with pncA, rpsA, and panD gene mutations. Diagn Microbiol Infect Dis. 2016;84(3):207–211. doi:10.1016/j.diagmicrobio.2015.10.01726775806
  • Xu P, Wu J, Yang C, et al. Prevalence and transmission of pyrazinamide resistant Mycobacterium tuberculosis in China. Tuberculosis. 2016;98:56–61. doi:10.1016/j.tube.2016.02.00827156619
  • Liu W, Chen J, Shen Y, et al. Phenotypic and genotypic characterization of pyrazinamide resistance among multidrug-resistant Mycobacterium tuberculosis clinical isolates in Hangzhou, China. Clin Microbiol Infect. 2018;24(9):1016e1011–1016 e1015. doi:10.1016/j.cmi.2017.12.012
  • Gopal P, Gruber G, Dartois V, Dick T. Pharmacological and molecular mechanisms behind the sterilizing activity of pyrazinamide. Trends Pharmacol Sci. 2019;40(12):930–940. doi:10.1016/j.tips.2019.10.00531704175
  • Alame-Emane AK, Xu P, Pierre-Audigier C, et al. Pyrazinamide resistance in Mycobacterium tuberculosis arises after rifampicin and fluoroquinolone resistance. Int J Tuberculosis Lung Dis. 2015;19(6):679–684. doi:10.5588/ijtld.14.0768
  • Zignol M, Dean AS, Alikhanova N, et al. Population-based resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones: results from a multicountry surveillance project. Lancet Infect Dis. 2016;16(10):1185–1192. doi:10.1016/S1473-3099(16)30190-627397590
  • Zignol M, Floyd K. Resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones - authors’ reply. Lancet Infect Dis. 2017;17(1):25. doi:10.1016/S1473-3099(16)30538-227998569
  • Budzik JM, Jarlsberg LG, Higashi J, et al. Pyrazinamide resistance, Mycobacterium tuberculosis lineage and treatment outcomes in San Francisco, California. PLoS One. 2014;9(4):e95645. doi:10.1371/journal.pone.009564524759760
  • Suzuki S, Horinouchi T, Furusawa C. Prediction of antibiotic resistance by gene expression profiles. Nat Commun. 2014;5:5792. doi:10.1038/ncomms679225517437
  • Raju S, Ye CJ. How mutations express themselves in blood-cell production. Nature. 2019;571(7765):329–330. doi:10.1038/d41586-019-02028-231308526
  • Bhuju S, Fonseca Lde S, Marsico AG, et al. Mycobacterium tuberculosis isolates from Rio de Janeiro reveal unusually low correlation between pyrazinamide resistance and mutations in the pncA gene. Infect Genetics Evol. 2013;19:1–6. doi:10.1016/j.meegid.2013.06.00823770140
  • Doustdar F, Khosravi AD, Farnia P. Mycobacterium tuberculosis genotypic diversity in pyrazinamide-resistant isolates of Iran. Microb Drug Resist. 2009;15(4):251–256. doi:10.1089/mdr.2009.006619857130
  • Jonmalung J, Prammananan T, Leechawengwongs M, Chaiprasert A. Surveillance of pyrazinamide susceptibility among multidrug-resistant Mycobacterium tuberculosis isolates from Siriraj Hospital, Thailand. BMC Microbiol. 2010;10:223. doi:10.1186/1471-2180-10-22320727143
  • Jureen P, Werngren J, Toro JC, Hoffner S. Pyrazinamide resistance and pncA gene mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2008;52(5):1852–1854. doi:10.1128/AAC.00110-0818316515
  • Whitfield MG, Soeters HM, Warren RM, et al. A global perspective on pyrazinamide resistance: systematic review and meta-analysis. PLoS One. 2015;10(7):e0133869. doi:10.1371/journal.pone.013386926218737
  • Li D, Hu Y, Werngren J, et al. Multicenter study of the emergence and genetic characteristics of pyrazinamide-resistant tuberculosis in China. Antimicrob Agents Chemother. 2016;60(9):5159–5166. doi:10.1128/AAC.02687-1527297481
  • Zheng X, Ning Z, Drobniewski F, et al. pncA mutations are associated with slower sputum conversion during standard treatment of multidrug-resistant tuberculosis. Int J Antimicrob Agents. 2017;49(2):183–188. doi:10.1016/j.ijantimicag.2016.10.01228012685
  • Spinato J, Boivin E, Belanger-Trudelle E, Fauchon H, Tremblay C, Soualhine H. Genotypic characterization of drug resistant Mycobacterium tuberculosis in Quebec, 2002-2012. BMC Microbiol. 2016;16(1):164. doi:10.1186/s12866-016-0786-427459848
  • Khan MT, Malik SI, Ali S, et al. Pyrazinamide resistance and mutations in pncA among isolates of Mycobacterium tuberculosis from Khyber Pakhtunkhwa, Pakistan. BMC Infect Dis. 2019;19(1):116. doi:10.1186/s12879-019-3764-230728001
  • Sheen P, Lozano K, Gilman RH, et al. pncA gene expression and prediction factors on pyrazinamide resistance in Mycobacterium tuberculosis. Tuberculosis. 2013;93(5):515–522. doi:10.1016/j.tube.2013.03.00523867321
  • Filipenko ML, Dymova MA, Cherednichenko AG, Khrapov EA, Mishukova OV, Schwartz YS. Detection of Mutations in Mycobacterium tuberculosis pncA gene by modified high-resolution melting curve analysis of PCR products. Bull Exp Biol Med. 2019;168(2):264–269. doi:10.1007/s10517-019-04688-631782002
  • Rodrigues Vde F, Telles MA, Ribeiro MO, Cafrune PI, Rossetti ML, Zaha A. Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis in Brazil. Antimicrob Agents Chemother. 2005;49(1):444–446. doi:10.1128/AAC.49.1.444-446.200515616332
  • Rahman A, Ferdous SS, Ahmed S, et al. Pyrazinamide susceptibility and pncA mutation profiles of mycobacterium tuberculosis among multidrug-resistant tuberculosis patients in Bangladesh. Antimicrob Agents Chemother. 2017;61:9. doi:10.1128/AAC.00511-17
  • Alexander DC, Ma JH, Guthrie JL, Blair J, Chedore P, Jamieson FB. Gene sequencing for routine verification of pyrazinamide resistance in Mycobacterium tuberculosis: a role for pncA but not rpsA. J Clin Microbiol. 2012;50(11):3726–3728. doi:10.1128/JCM.00620-1222895038
  • Tan Y, Hu Z, Zhang T, et al. Role of pncA and rpsA gene sequencing in detection of pyrazinamide resistance in Mycobacterium tuberculosis isolates from southern China. J Clin Microbiol. 2014;52(1):291–297. doi:10.1128/JCM.01903-1324131688
  • Khan MT, Malik SI, Bhatti AI, et al. Pyrazinamide-resistant mycobacterium tuberculosis isolates from Khyber Pakhtunkhwa and rpsA mutations. J Biol Regul Homeost Agents. 2018;32(3):705–709.29921403