175
Views
1
CrossRef citations to date
0
Altmetric
Original Research

The Impacts of Deep Surgical Site Infections on Readmissions, Length of Stay, and Costs: A Matched Case–Control Study Conducted in an Academic Hospital in the Netherlands

ORCID Icon, ORCID Icon, , ORCID Icon, ORCID Icon, ORCID Icon & show all
Pages 3365-3374 | Published online: 30 Sep 2020

References

  • Merkow RP, Ju MH, Chung JW, et al. Underlying reasons associated with hospital readmission following surgery in the United States. JAMA. 2015;313(5):483–495. doi:10.1001/jama.2014.1861425647204
  • Ou L, Chen J, Hillman K, et al. The impact of post-operative sepsis on mortality after hospital discharge among elective surgical patients: a population-based cohort study. Crit Care. 2017;21(1):34. doi:10.1186/s13054-016-1596-728219408
  • Cristofolini M, Worlitzsch D, Wienke A, Silber R-E, Borneff-Lipp M. Surgical site infections after coronary artery bypass graft surgery: incidence, perioperative hospital stay, readmissions, and revision surgeries. Infection. 2012;40(4):397–404. doi:10.1007/s15010-012-0275-022700379
  • Fried E, Weissman C, Sprung C. Postoperative sepsis. Curr Opin Crit Care. 2011;17(4):396–401. doi:10.1097/MCC.0b013e328348bee221677580
  • Vogel TR, Dombrovskiy VY, Carson JL, Graham AM, Lowry SF. Postoperative sepsis in the United States. Ann Surg. 2010;252(6):1065–1071. doi:10.1097/SLA.0b013e3181dcf36e20571363
  • Mu Y, Edwards JR, Horan TC, Berrios-Torres SI, Fridkin SK. Improving risk-adjusted measures of surgical site infection for the National Healthcare Safely Network. Infect Control Hosp Epidemiol. 2011;32(10):970–986. doi:10.1086/66201621931247
  • Purba AKR, Setiawan D, Bathoorn E, Postma MJ, Dik J-WH, Friedrich AW. Prevention of surgical site infections: a systematic review of cost analyses in the use of prophylactic antibiotics. Front Pharmacol. 2018;9:776. doi:10.3389/fphar.2018.0077630072898
  • Cassini A, Plachouras D, Eckmanns T, et al. Burden of six healthcare-associated infections on European Population Health: estimating incidence-based disability-adjusted life years through a Population Prevalence-Based Modelling Study. PLoS Med. 2016;13(10):e1002150. doi:10.1371/journal.pmed.100215027755545
  • Horan TC, Gaynes RP, Martone WJ, Jarvis WR, Emori TG. CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol. 1992;13(10):606–608. doi:10.2307/301484641334988
  • Kaye KS, Schmit K, Pieper C, et al. The effect of increasing age on the risk of surgical site infection. J Infect Dis. 2005;191(7):1056–1062. doi:10.1086/42862615747239
  • Neumayer L, Hosokawa P, Itani K, El-Tamer M, Henderson WG, Khuri SF. Multivariable predictors of postoperative surgical site infection after general and vascular surgery: results from the patient safety in surgery study. J Am Coll Surg. 2007;204(6):1178–1187. doi:10.1016/j.jamcollsurg.2007.03.02217544076
  • Culver DH, Horan TC, Gaynes RP, et al. Surgical wound infection rates by wound class, operative procedure, and patient risk index. National Nosocomial Infections Surveillance System. Am J Med. 1991;91(3):152S–157S. doi:10.1016/0002-9343(91)90361-z1656747
  • Busch C-J, Knecht R, Munscher A, Matern J, Dalchow C, Lorincz BB. Postoperative antibiotic prophylaxis in clean-contaminated head and neck oncologic surgery: a retrospective cohort study. Eur Arch Otorhinolaryngol. 2016;273(9):2805–2811. doi:10.1007/s00405-015-3856-626683471
  • Shrestha S, Wenju P, Shrestha R, Karmacharya RM. Incidence and risk factors of surgical site infections in Kathmandu University Hospital, Kavre, Nepal. Kathmandu Univ Med J (KUMJ). 2016;14(54):107–111.28166064
  • Galli R, Banz V, Fenner H, Metzger J. Laparoscopic approach in perforated appendicitis: increased incidence of surgical site infection? Surg Endosc. 2013;27(8):2928–2933. doi:10.1007/s00464-013-2858-y23443482
  • Dik J-WH, Poelman R, Friedrich AW, et al. An integrated stewardship model: antimicrobial, infection prevention and diagnostic (AID). Future Microbiol. 2016;11(1):93–102. doi:10.2217/fmb.15.9926323589
  • Friedrich AW. Control of hospital acquired infections and antimicrobial resistance in Europe: the way to go. Wien Med Wochenschr. 2019;169(Suppl 1):25–30. doi:10.1007/s10354-018-0676-5
  • Koek MBG, van der Kooi TII, Stigter FCA, et al. Burden of surgical site infections in the Netherlands: cost analyses and disability-adjusted life years. J Hosp Infect. 2019;103(3):293–302. doi:10.1016/j.jhin.2019.07.01031330166
  • Kivi M, Manniën J, Wille JC, van den Hof S. Surgical site infection surveillance and the predictive power of the National Nosocomial Infection Surveillance index as compared with alternative determinants in The Netherlands. Am J Infect Control. 2008;36(3, Supplement):S27–S31. doi:10.1016/j.ajic.2007.07.006
  • Mannien J, van den Hof S, Brandt C, Behnke M, Wille JC, Gastmeier P. Comparison of the National Surgical Site Infection surveillance data between The Netherlands and Germany: PREZIES versus KISS. J Hosp Infect. 2007;66(3):224–231. doi:10.1016/j.jhin.2007.03.02417512635
  • Coello R, Charlett A, Wilson J, Ward V, Pearson A, Borriello P. Adverse impact of surgical site infections in English hospitals. J Hosp Infect. 2005;60(2):93–103. doi:10.1016/j.jhin.2004.10.01915866006
  • Lawson EH, Hall BL, Ko CY. Risk factors for superficial vs deep/organ-space surgical site infections: implications for quality improvement initiatives. JAMA Surg. 2013;148(9):849–858. doi:10.1001/jamasurg.2013.292523864108
  • European Centre for Disease Prevention and Control. Surgical site infections. Available from: https://www.ecdc.europa.eu/en/publications-data/directory-guidance-prevention-and-control/healthcare-associated-infections-0. Accessed 122, 2019.
  • Health NCC for W and C. Surgical Site Infection: Prevention and Treatment of Surgical Site Infection. London, The United Kingdom; 2008.
  • European Centre for Disease Prevention and Control (ECDC). Surveillance of surgical site infections and prevention indicators in European hospitals. 2017 Available from: https://www.ecdc.europa.eu/sites/portal/files/documents/HAI-Net-SSI-protocol-v2.2.pdf. Accessed 117, 2020.
  • Garner JS. CDC guideline for prevention of surgical wound infections, 1985. Supersedes guideline for prevention of surgical wound infections published in 1982. (Originally published in November 1985). Revised. Infect Control. 1986;7(3):193–200. doi:10.1017/S01959417000640803633903
  • Tacconelli E, Muller NF, Lemmen S, Mutters NT, Hagel S, Meyer E. Infection risk in sterile operative procedures. Dtsch Arztebl Int. 2016;113(16):271–278. doi:10.3238/arztebl.2016.027127159141
  • Simmons BP. CDC guidelines for the prevention and control of nosocomial infections guideline for prevention of surgical wound infections. Am J Infect Control. 1983;11(4):133–143. doi:10.1016/0196-6553(83)90030-56556029
  • Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for prevention of surgical site infection, 1999. Centers for Disease Control and Prevention (CDC) hospital infection control practices advisory committee. Am J Infect Control. 1999;27(2):97–132; quiz 133–134; discussion 96. doi:10.1016/S0196-6553(99)70088-X
  • Hansen LO, Young RS, Hinami K, Leung A, Williams MV. Interventions to reduce 30-day rehospitalization: a systematic review. Ann Intern Med. 2011;155(8):520–528. doi:10.7326/0003-4819-155-8-201110180-0000822007045
  • McPhee JT, Nguyen LL, Ho KJ, Ozaki CK, Conte MS, Belkin M. Risk prediction of 30-day readmission after infrainguinal bypass for critical limb ischemia. J Vasc Surg. 2013;57(6):1481–1488. doi:10.1016/j.jvs.2012.11.07423395204
  • Saunders RS, Fernandes-Taylor S, Rathouz PJ, et al. Outpatient follow-up versus 30-day readmission among general and vascular surgery patients: a case for redesigning transitional care. Surgery. 2014;156(4):949–956. doi:10.1016/j.surg.2014.06.04125239351
  • UMCG passantenprijzen 2014. Available from: https://docplayer.nl/12632899-Umcg-passantenprijzen-2014-dbc-zorgproducten-verzekerde-zorg-01-06-2014.html. Accessed 1111, 2019.
  • UMCG passantenprijzen 2015. Available from: https://docplayer.nl/15645564-Umcg-passantenprijzen-2015-dbc-zorgproducten-verzekerde-zorg-01-01-2015.html. Accessed 1111, 2019.
  • UMCG passantenprijzen 2016. Available from: https://docplayer.nl/28813274-Umcg-passantenprijzen-2016-dbc-zorgproducten-verzekerde-zorg-per.html. Accessed 1111, 2019.
  • World Health Organization. Global guidelines on the prevention of surgical site infection. 2016 Available from: https://www.who.int/gpsc/ssi-prevention-guidelines/en/. Accessed 11, 2020.
  • Desgagné A, Castilloux AM, Angers JF, LeLorier J. The use of the bootstrap statistical method for the pharmacoeconomic cost analysis of skewed data. Pharmacoeconomics. 1998;13(5 Pt 1):487–497. doi:10.2165/00019053-199813050-0000210180748
  • Rascati KL, Smith MJ, Neilands T. Dealing with skewed data: an example using asthma-related costs of medicaid clients. Clin Ther. 2001;23(3):481–498. doi:10.1016/s0149-2918(01)80052-711318082
  • Spruance SL, Reid JE, Grace M, Samore M. Hazard ratio in clinical trials. Antimicrob Agents Chemother. 2004;48(8):2787–2792. doi:10.1128/AAC.48.8.2787-2792.200415273082
  • Dik J-WH, Sinha B, Lokate M, et al. Positive impact of infection prevention on the management of nosocomial outbreaks at an academic hospital. Future Microbiol. 2016;11(10):1249–1259. doi:10.2217/fmb-2016-003027424627
  • Cosgrove MS. Infection control in the operating room. Crit Care Nurs Clin North Am. 2015;27(1):79–87. doi:10.1016/j.cnc.2014.10.00425725538
  • World Health Organization. Global Guidelines for the Prevention of Surgical Site Infection. Geneva; 2018.
  • Bratzler DW, Dellinger EP, Olsen KM, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J Heal Pharm. 2013;70(3):195–283. doi:10.2146/ajhp120568
  • Badia JM, Casey AL, Petrosillo N, Hudson PM, Mitchell SA, Crosby C. Impact of surgical site infection on healthcare costs and patient outcomes: a systematic review in six European countries. J Hosp Infect. 2017;96(1):1–15. doi:10.1016/j.jhin.2017.03.00428410761
  • Kashimura N, Kusachi S, Konishi T, et al. Impact of surgical site infection after colorectal surgery on hospital stay and medical expenditure in Japan. Surg Today. 2012;42(7):639–645. doi:10.1007/s00595-012-0126-822286573
  • Mahmoud NN, Turpin RS, Yang G, Saunders WB. Impact of surgical site infections on length of stay and costs in selected colorectal procedures. Surg Infect (Larchmt). 2009;10(6):539–544. doi:10.1089/sur.2009.00619708769
  • Graf K, Ott E, Vonberg R-P, et al. Surgical site infections–economic consequences for the health care system. Langenbeck’s Arch Surg. 2011;396(4):453–459. doi:10.1007/s00423-011-0772-021404004
  • Graf K, Ott E, Vonberg R-P, Kuehn C, Haverich A, Chaberny IF. Economic aspects of deep sternal wound infections. Eur J Cardiothorac Surg. 2010;37(4):893–896. doi:10.1016/j.ejcts.2009.10.00519896860
  • Kusachi S, Kashimura N, Konishi T, et al. Length of stay and cost for surgical site infection after abdominal and cardiac surgery in Japanese hospitals: multi-center surveillance. Surg Infect (Larchmt). 2012;13(4):257–265. doi:10.1089/sur.2011.00722871224
  • Wick EC, Shore AD, Hirose K, et al. Readmission rates and cost following colorectal surgery. Dis Colon Rectum. 2011;54(12):1475–1479. doi:10.1097/DCR.0b013e31822ff8f022067174
  • Trick WE, Scheckler WE, Tokars JI, et al. Modifiable risk factors associated with deep sternal site infection after coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2000;119(1):108–114. doi:10.1016/s0022-5223(00)70224-810612768
  • Borger MA, Rao V, Weisel RD, et al. Deep sternal wound infection: risk factors and outcomes. Ann Thorac Surg. 1998;65(4):1050–1056. doi:10.1016/s0003-4975(98)00063-09564926
  • Jencks SF, M V W, Coleman EA. Rehospitalizations among patients in the medicare fee-for-service program. N Engl J Med. 2009;360(14):1418–1428. doi:10.1056/NEJMsa080356319339721
  • Kaye KS, Anderson DJ, Sloane R, et al. The effect of surgical site infection on older operative patients. J Am Geriatr Soc. 2009;57(1):46–54. doi:10.1111/j.1532-5415.2008.02053.x19054183
  • Lu Q, Xie S-Q, Chen S-Y, Chen L-J, Qin Q. Experience of 1166 thyroidectomy without use of prophylactic antibiotic. Biomed Res Int. 2014;2014:758432. doi:10.1155/2014/75843224900986
  • Saeedinia S, Nouri M, Azarhomayoun A, et al. The incidence and risk factors for surgical site infection after clean spinal operations: a prospective cohort study and review of the literature. Surg Neurol Int. 2015;6(1):154. doi:10.4103/2152-7806.16619426500800
  • Gheorghe A, Moran G, Duffy H, Roberts T, Pinkney T, Calvert M. Health utility values associated with surgical site infection: a systematic review. Value Health. 2015;18(8):1126–1137. doi:10.1016/j.jval.2015.08.00426686800
  • World Medical Association. Ethical Principles for Medical Research Involving Human Subjects Version 2013; 64th World Medical Association General, Fortaleza, BrazilAssembly, October 2013. 2013 Available from: https://www.wma.net/policies-post/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects/. Accessed 711, 2019.