201
Views
0
CrossRef citations to date
0
Altmetric
Original Research

Amoxicillin Utilization Pattern at Governmental Hospitals in Eastern Ethiopia

ORCID Icon, ORCID Icon, ORCID Icon, & ORCID Icon
Pages 193-203 | Published online: 20 Jan 2021

References

  • Ferech M, Coenen S, Malhotra-Kumar S, et al. European surveillance of antimicrobial consumption (ESAC): outpatient antibiotic use in Europe. J Antimicrob Chemother. 2006;58(2):401–407.16735414
  • van Bijnen EM, den Heijer CD, Paget WJ, et al. The appropriateness of prescribing antibiotics in the community in Europe: study design. BMC Infect Dis. 2011;11(1):293. doi:10.1186/1471-2334-11-29322032233
  • Ahiabu M-A, Tersbøl BP, Biritwum R, Bygbjerg IC, Magnussen P. A retrospective audit of antibiotic prescriptions in primary health-care facilities in Eastern Region, Ghana. Health Policy Plan. 2015;31(2):250–258. doi:10.1093/heapol/czv04826045328
  • Buke AC, Ermertcan S, Hosgor-Limoncu M, Ciceklioglu M, Eren S. Rational antibiotic use and academic staff. Int J Antimicrob Agents. 2003;21(1):63–66. doi:10.1016/S0924-8579(02)00272-812507839
  • Arda B, Sipahi OR, Yamazhan T, et al. Short-term effect of antibiotic control policy on the usage patterns and cost of antimicrobials, mortality, nosocomial infection rates and antibacterial resistance. J Infect. 2007;55(1):41–48. doi:10.1016/j.jinf.2007.02.01417512598
  • Gajdács M, Albericio F. Antibiotic Resistance: From the Bench to Patients. Multidisciplinary Digital Publishing Institute; 2019.
  • Gajdács M, Paulik E, Szabó A. Knowledge, attitude and practice of community pharmacists regarding antibiotic use and infectious diseases: a cross-sectional survey in Hungary (KAPPhA-HU). Antibiotics. 2020;9(2):41. doi:10.3390/antibiotics9020041
  • Ayinalem GA, Gelaw BK, Belay AZ, Linjesa JL. Drug use evaluation of ceftriaxone in medical ward of Dessie Referral Hospital, North East Ethiopia. Int J Chem Nat Sci. 2013;1(1):12–16.
  • Hamishehkar H, Ebrahimi D, Mahmoodpoor A, Mashayekhi S, Asgharian P, Reazee H. Drug utilization evaluation of vancomycin in a teaching hospital in Tabriz-Iran. Pharm Sci. 2015;21(1):25. doi:10.15171/PS.2015.13
  • Gajdács M. The concept of an ideal antibiotic: implications for drug design. Molecules. 2019;24(5):892. doi:10.3390/molecules24050892
  • Aslam A, Gajdács M, Zin CS, et al. Evidence of the practice of self-medication with antibiotics among the lay public in low-and middle-income countries: a scoping review. Antibiotics. 2020;9(9):597. doi:10.3390/antibiotics9090597
  • Aslam A, Gajdács M, Zin CS, Binti Abd Rahman NS, Ahmed SI, Jamshed SQ. Public awareness and practices towards self-medication with antibiotics among the Malaysian population. A development of questionnaire and pilot-testing. Antibiotics. 2020;9(2):97. doi:10.3390/antibiotics9020097
  • Williams VR, Callery S, Vearncombe M, Simor AE. The role of colonization pressure in nosocomial transmission of methicillin-resistant Staphylococcus aureus. Am J Infect Control. 2009;37(2):106–110. doi:10.1016/j.ajic.2008.05.00718945520
  • Lipsitch M, Samore MH. Antimicrobial use and antimicrobial resistance: a population perspective. Emerg Infect Dis. 2002;8(4):347. doi:10.3201/eid0804.01031211971765
  • Wise L. Risks and benefits of (pharmaco) epidemiology. Ther Adv Drug Saf. 2011;2(3):95–102. doi:10.1177/204209861140492025083205
  • Fahimi F, Baniasadi S, Behzadnia N, Varahram F, Ghazi Tabatabaie L. Enoxaparin utilization evaluation: an observational prospective study in medical inpatients. Iran J Pharm Sci. 2010;77–82.
  • Prescott JF. Beta-lactam antibiotics: penam penicillins. Antimicrob Ther Vet Med. 2006;3:105–133.
  • Blumental D, Brunton LL. Goodman & Gilman’s Manual of Pharmacology and Therapeutics. 2008:728–750.
  • Prevention ECfD, Control. Antimicrobial Consumption in the EU/EEA, Annual Epidemiological Report for 2018. Stockholm: ECDC; 2019.
  • Mollahaliloglu S, Alkan A, Donertas B, Ozgulcu S, Akici A. Assessment of antibiotic prescribing at different hospitals and primary health care facilities. Saudi Pharm J. 2013;21(3):281–291. doi:10.1016/j.jsps.2012.10.00423960845
  • Ab Rahman N, Teng CL, Sivasampu S. Antibiotic prescribing in public and private practice: a cross-sectional study in primary care clinics in Malaysia. BMC Infect Dis. 2016;16(1):208. doi:10.1186/s12879-016-1530-227188538
  • Worku F, Tewahido D. Retrospective assessment of antibiotics prescribing at public primary healthcare facilities in Addis Ababa, Ethiopia. Interdiscip Perspect Infect Dis. 2018;2018:2018. doi:10.1155/2018/4323769
  • Adisa R, Fakeye TO, Aindero VO. Evaluation of prescription pattern and patients’ opinion on healthcare practices in selected primary healthcare facilities in Ibadan, South-Western Nigeria. Afr Health Sci. 2015;15(4):1318–1329. doi:10.4314/ahs.v15i4.3526958037
  • Dong L, Yan H, Wang D. Antibiotic prescribing patterns in village health clinics across 10 provinces of Western China. J Antimicrob Chemother. 2008;62(2):410–415. doi:10.1093/jac/dkn15318400805
  • Bilal AI, Osman ED, Mulugeta A. Assessment of medicines use pattern using World Health Organization’s prescribing, patient care and health facility indicators in selected health facilities in eastern Ethiopia. BMC Health Serv Res. 2016;16(1):144. doi:10.1186/s12913-016-1414-627106610
  • Desalegn AA. Assessment of drug use pattern using WHO prescribing indicators at Hawassa University teaching and referral hospital, south Ethiopia: a cross-sectional study. BMC Health Serv Res. 2013;13(1):170. doi:10.1186/1472-6963-13-17023647871
  • Gebeyehu E, Bantie L, Azage M, Ciccozzi M. Inappropriate use of antibiotics and its associated factors among urban and rural communities of Bahir Dar City administration, Northwest Ethiopia. PLoS One. 2015;10(9):e0138179. doi:10.1371/journal.pone.013817926379031
  • Ocan M, Bwanga F, Bbosa GS, et al. Patterns and predictors of self-medication in northern Uganda. PLoS One. 2014;9(3):e92323. doi:10.1371/journal.pone.009232324658124
  • Widayati A. Self Medication with Antibiotics in Yogyakarta City Indonesia. 2013.
  • Ramay BM, Lambour P, Cerón A. Comparing antibiotic self-medication in two socio-economic groups in Guatemala City: a descriptive cross-sectional study. BMC Pharmacol Toxicol. 2015;16(1):11. doi:10.1186/s40360-015-0011-325928897
  • Mitsi G, Jelastopulu E, Basiaris H, Skoutelis A, Gogos C. Patterns of antibiotic use among adults and parents in the community: a questionnaire-based survey in a Greek urban population. Int J Antimicrob Agents. 2005;25(5):439–443. doi:10.1016/j.ijantimicag.2005.02.00915848301
  • Skliros E, Merkouris P, Papazafiropoulou A, et al. Self-medication with antibiotics in rural population in Greece: a cross-sectional multicenter study. BMC Fam Pract. 2010;11(1):58. doi:10.1186/1471-2296-11-5820691111
  • Togoobaatar G, Ikeda N, Ali M, et al. Survey of non-prescribed use of antibiotics for children in an urban community in Mongolia. Bull World Health Organ. 2010;88(12):930–936. doi:10.2471/BLT.10.07900421124718
  • Organization WH. WHO Report on Surveillance of Antibiotic Consumption: 2016–2018 Early Implementation. 2018.
  • Fenta A, Belay M, Mekonnen E. Assessment of antibacterial drug exposure patterns of patient encounters seen by different categories of prescribers at health institutions in Bahir Dar, Ethiopia. Ethiop Med J. 2013;51(1):33–39.23930489
  • Getachew E, Aragaw S, Adissie W, Agalu A. Antibiotic prescribing pattern in a referral hospital in Ethiopia. Afr J Pharm Pharmacol. 2013;7(38):2657–2661. doi:10.5897/AJPP12.505
  • Spivak ES, Cosgrove SE, Srinivasan A. Measuring appropriate antimicrobial use: attempts at opening the black box. Clin Infect Dis. 2016;63(12):ciw658. doi:10.1093/cid/ciw658
  • Hara GL, Kanj SS, Pagani L, et al. Ten key points for the appropriate use of antibiotics in hospitalised patients: a consensus from the antimicrobial stewardship and resistance working groups of the international society of chemotherapy. Int J Antimicrob Agents. 2016;48(3):239–246. doi:10.1016/j.ijantimicag.2016.06.01527502752
  • Slama TG, Amin A, Brunton SA, et al. A Clinician’s Guide to the Appropriate and Accurate Use of Antibiotics: The Council for Appropriate and Rational Antibiotic Therapy (CARAT) Criteria. Elsevier; 2005.
  • Kotwani A, Holloway K. Access to antibiotics in New Delhi, India: implications for antibiotic policy. J Pharm Policy Pract. 2013;6(1):6. doi:10.1186/2052-3211-6-624764541
  • Goossens H, Ferech M, Vander Stichele R, Elseviers M, Group EP. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet. 2005;365(9459):579–587. doi:10.1016/S0140-6736(05)70799-615708101
  • Gajdács M, Paulik E, Szabó A. Public knowledge, attitude and practices towards antibiotics and antibiotic resistance: a cross-sectional study in Szeged District, Hungary. Acta Pharm Hung. 2020;90(1):5–14. doi:10.33892/aph.2020.90.5-14
  • Chlabicz M, Chlabicz S, Marcinowicz L, Rogowska-Szadkowska D, Pytel-Krolczuk B, Leszczyńska K. Outpatient use of systemic antibiotics in Poland: 2004–2008. Przegl Epidemiol. 2014;68(3):435–441.25391007
  • Sisay M, Gashaw T, Amare F, Tesfa T, Baye Y. Hospital-level antibacterial prescribing and its completeness in ethiopia: did it adhere to good prescribing practice? Int J Gen Med. 2020;13:1025. doi:10.2147/IJGM.S28069633192086
  • Haadi A, Abdullah S, Faqruddin M, Khan MN, Khan MA, Omer M. A systemic review on antibiotic use evaluation in paediatrics. World J Pharm Sci. 2014;2:243–246.
  • HRHB. Harari Reginal State Annual Bulletin. 2014.
  • Food M, Administration HC, Ethiopia CAo. Standard Treatment Guidelines for General Hospitals. 2014.
  • Gajdacs M. Intravenous or oral antibiotic therapy: sophie’s choice? Gen Intern Med Clin Innov. 2019;4(2):1–2. doi:10.15761/GIMCI.1000176
  • Almeida L, Schmauch A, Bergström S. A randomised study on the impact of peroral amoxicillin in women with prelabour rupture of membranes preterm. Gynecol Obstet Invest. 1996;41(2):82–84. doi:10.1159/0002920468838964
  • Lovett SM, Weiss JD, Diogo MJ, Williams PT, Garite TJ. A prospective, double-blind, randomized, controlled clinical trial of ampicillin-sulbactam for preterm premature rupture of membranes in women receiving antenatal corticosteroid therapy. Am J Obstet Gynecol. 1997;176(5):1030–1038. doi:10.1016/S0002-9378(97)70398-39166164
  • Mercer BM, Miodovnik M, Thurnau GR, et al. Antibiotic therapy for reduction of infant morbidity after preterm premature rupture of the membranes: a randomized controlled trial. JAMA. 1997;278(12):989–995. doi:10.1001/jama.1997.035501200490329307346
  • Czeizel AE, Rockenbauer M, Sørensen HT, Olsen J. Augmentin treatment during pregnancy and the prevalence of congenital abnormalities: a population-based case-control teratologic study. Eur J Obstet Gynecol Reprod Biol. 2001;97(2):188–192. doi:10.1016/S0301-2115(00)00545-511451547
  • Jepsen P, Skriver MV, Floyd A, Lipworth L, Schønheyder HC, Sørensen HT. A population‐based study of maternal use of amoxicillin and pregnancy outcome in Denmark. Br J Clin Pharmacol. 2003;55(2):216–221. doi:10.1046/j.1365-2125.2003.01750.x12580995
  • Ito S, Blajchman A, Stephenson M, Eliopoulos C, Koren G. Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication. Am J Obstet Gynecol. 1993;168(5):1393–1399. doi:10.1016/S0002-9378(11)90771-68498418
  • Benyamini L, Merlob P, Stahl B, et al. The safety of amoxicillin/clavulanic acid and cefuroxime during lactation. Ther Drug Monit. 2005;27(4):499–502. doi:10.1097/01.ftd.0000168294.25356.d016044108
  • Yazdani-Brojeni P, Garcia-Bournissen F, Fujii H, Tanoshima R, Ito S. Relative bioequivalence of amoxicillin dissolved in breast milk. Arch Dis Child. 2014;99(3):258–261. doi:10.1136/archdischild-2013-30515124363363
  • Bookstaver PB, Bland CM, Griffin B, Stover KR, Eiland LS, McLaughlin M. A review of antibiotic use in pregnancy. Pharmacotherapy. 2015;35(11):1052–1062. doi:10.1002/phar.164926598097
  • Kaur SP, Rao R, Nanda S. Amoxicillin: a broad spectrum antibiotic. Int J Pharm Pharm Sci. 2011;3(3):30–37.
  • WHO. Critically Important Antimicrobials for Human Medicine: Ranking of Antimicrobial Agents for Risk Management of Antimicrobial Resistance Due to Non-Human Use. 2017.
  • Brodie D, Griggs J, Cunningham K. Comparative study of cefuroxime axetil suspension and amoxycillin syrup in the treatment of acute otitis media in general practice. J Int Med Res. 1990;18(3):235–239. doi:10.1177/0300060590018003092113874
  • Abula T, Worku A. Self-medication in three towns of North West Ethiopia. Ethiop J Health Dev. 2001;15(1):25–30. doi:10.4314/ejhd.v15i1.9893
  • Scicluna EA, Borg MA, Gür D, et al. Self-medication with antibiotics in the ambulatory care setting within the Euro-Mediterranean region; results from the ARMed project. J Infect Public Health. 2009;2(4):189–197. doi:10.1016/j.jiph.2009.09.00420701882
  • Alshakka M, Said K, Babakri M, et al. A study on antibiotics prescribing pattern at outpatient department in four hospitals in aden-yemen. J Pharm Pract Community Med. 2016;2(3):88–93. doi:10.5530/jppcm.2016.3.5
  • Rajpurkar P, Irvin J, Zhu K, et al. Chexnet: radiologist-level pneumonia detection on chest x-rays with deep learning. arXiv Preprint arXiv. 2017.
  • Sisay M, Mengistu G, Edessa D. Epidemiology of self-medication in Ethiopia: a systematic review and meta-analysis of observational studies. BMC Pharmacol Toxicol. 2018;19(1):56. doi:10.1186/s40360-018-0248-830201045
  • Al-Azzam SI, Al-Husein BA, Alzoubi F, Masadeh MM, Al-Horani A. Self-medication with antibiotics in Jordanian population. Int J Occup Med Environ Health. 2007;20(4):373. doi:10.2478/v10001-007-0038-918165197
  • Ayalew MB. Self-medication practice in Ethiopia: a systematic review. Patient Prefer Adherence. 2017;11:401. doi:10.2147/PPA.S13149628280312
  • Grigoryan L, Haaijer-Ruskamp FM, Burgerhof JG, et al. Self-medication with antimicrobial drugs in Europe. Emerg Infect Dis. 2006;12(3):452. doi:10.3201/eid1203.05099216704784
  • Nakhaee M, Vatankhah S. Prevalence and cause of self-medication in iran: a systematic review and meta-analysis on health center based studies. J Biochem Tech. 2019;(2):90–105.
  • Mboya EA, Sanga LA, Ngocho JS. Irrational use of antibiotics in the moshi municipality northern Tanzania: a cross sectional study. Pan Afr Med J. 2018;31:31. doi:10.11604/pamj.2018.31.165.1599130918558
  • Siraj J, Ahmed S. Evaluation of crystalline penicillin use in pediatrics ward of Jimma University specialized hospital, South West Ethiopia. Clin Exp Pharmacol. 2013;3(135):2161–1459.1000135.
  • Kaliamoorthy K, Sankaralingam R, Punniyakotti S, Janardhan V, Cheekala UMR. Drug utilization evaluation of third generation cephalosporins using core drug use indicators. Pak J Pharm Sci. 2012;25(2):339–342.22459458
  • Reveiz L, Cardona AF. Antibiotics for acute laryngitis in adults. Cochrane Database Syst Rev. 2015;(5). doi:10.1002/14651858.CD004783.pub5.
  • Nice C. Respiratory Tract Infections-Antibiotic Prescribing: Prescribing of Antibiotics for Self-Limiting Respiratory Tract Infections in Adults and Children in Primary Care. 2008.
  • El Garch F, de Jong A, Simjee S, et al. Monitoring of antimicrobial susceptibility of respiratory tract pathogens isolated from diseased cattle and pigs across Europe, 2009–2012: vetPath results. Vet Microbiol. 2016;194:11–22. doi:10.1016/j.vetmic.2016.04.00927102206
  • Yamamoto K, Kijima M, Yoshimura H, Takahashi T. Antimicrobial susceptibilities of Erysipelothrix rhusiopathiae isolated from pigs with swine erysipelas in Japan, 1988–1998. J Vet Med B. 2001;48(2):115–126. doi:10.1046/j.1439-0450.2001.00427.x
  • Goldman RD, Society CP, Therapy D, Committee HS. Treating cough and cold: guidance for caregivers of children and youth. Paediatr Child Health. 2011;16(9):564–566. doi:10.1093/pch/16.9.56423115499
  • CVM F. Guidance for Industry# 152. Evaluating the Safety of Antimicrobial New Animal Drugs with Regard to Their Microbiological Effects on Bacteria of Human Health Concern. Rockville, MD: Center for Veterinary Medicine, Food and Drug Administration; 2003.
  • EMA. Answers to the Requests for Scientific Advice on the Impact on Public Health and Animal Health of the Use of Antibiotics in Animals. 2014.
  • Geddes AM, Gould IM. Ampicillin, Amoxicillin and Other Ampicillin-Like Penicillins. Kucers’ the Use of Antibiotics. 6th ed. London (UK): Hodder Arnold; 2010:65.