303
Views
23
CrossRef citations to date
0
Altmetric
Original Research

Clinical Outcomes and Prevalence of Hepatitis E Virus (HEV) Among Non-A-C Hepatitis Patients in Egypt

ORCID Icon, ORCID Icon, , ORCID Icon, , , , & show all
Pages 59-69 | Published online: 12 Jan 2021

References

  • Sayed IM, Vercouter AS, Abdelwahab SF, Vercauteren K, Meuleman P. Is hepatitis E virus an emerging problem in industrialized countries? Hepatology (Baltimore, Md). 2015;62(6):1883–1892. doi:10.1002/hep.27990
  • Smith DB, Simmonds P, Izopet J, et al. Proposed reference sequences for hepatitis E virus subtypes. J General Virol. 2016;97(3):537–542. doi:10.1099/jgv.0.000393
  • Rein DB, Stevens GA, Theaker J, Wittenborn JS, Wiersma ST. The global burden of hepatitis E virus genotypes 1 and 2 in 2005. Hepatology (Baltimore, Md). 2012;55(4):988–997. doi:10.1002/hep.25505
  • Sharma S, Kumar A, Kar P, et al. Risk factors for vertical transmission of hepatitis E virus infection. J Viral Hepat. 2017;24(11):1067–1075. doi:10.1111/jvh.1273028570034
  • Pavio N, Doceul V, Bagdassarian E, Johne R. Recent knowledge on hepatitis E virus in Suidae reservoirs and transmission routes to human. Vet Res. 2017;48(1):78. doi:10.1186/s13567-017-0483-929157309
  • Abravanel F, Lhomme S, El Costa H, et al. Rabbit Hepatitis E virus infections in humans, France. Emerg Infect Dis. 2017;23(7):1191–1193. doi:10.3201/eid2307.17031828628452
  • Colson P, Borentain P, Queyriaux B, et al. Pig liver sausage as a source of hepatitis E virus transmission to humans. J Infect Dis. 2010;202(6):825–834. doi:10.1086/65589820695796
  • Lee GH, Tan BH, Teo EC, et al. Chronic infection with camelid hepatitis E virus in a liver transplant recipient who regularly consumes camel meat and milk. Gastroenterology. 2016;150(2):355–357.e353. doi:10.1053/j.gastro.2015.10.04826551551
  • Sayed IM, Vercauteren K, Abdelwahab SF, Meuleman P. The emergence of hepatitis E virus in Europe. Future Virology. 2015;10(6):763–778. doi:10.2217/fvl.15.29
  • Al-Sadeq DW, Majdalawieh AF. Seroprevalence and incidence of hepatitis E virus among blood donors, a review. 2017;27(5):e1937. doi:10.1002/rmv.1937
  • Péron JM, Bureau C, Poirson H, et al. Fulminant liver failure from acute autochthonous hepatitis E in France, description of seven patients with acute hepatitis E and encephalopathy. J Viral Hepat. 2007;14(5):298–303. doi:10.1111/j.1365-2893.2007.00858.x17439518
  • Aherfi S, Borentain P, Raissouni F, et al. Liver transplantation for acute liver failure related to autochthonous genotype 3 hepatitis E virus infection. Clinics and Research in Hepatology and Gastroenterology. 2014;38(1):24–31. doi:10.1016/j.clinre.2013.05.01324462173
  • Kamar N, Selves J, Mansuy JM, et al. Hepatitis E virus and chronic hepatitis in organ-transplant recipients. N Engl J Med. 2008;358(8):811–817. doi:10.1056/NEJMoa070699218287603
  • Kenfak-Foguena A, Schöni-Affolter F, Bürgisser P, et al. Hepatitis E Virus seroprevalence and chronic infections in patients with HIV, Switzerland. Emerg Infect Dis. 2011;17(6):1074–1078. doi:10.3201/eid/1706.10106721749774
  • Péron JM, Abravanel F, Guillaume M, et al. Treatment of autochthonous acute hepatitis E with short-term ribavirin, a multicenter retrospective study. Liver Int. 2016;36(3):328–333. doi:10.1111/liv.1291126179015
  • Kamar N, Izopet J, Tripon S, et al. Ribavirin for chronic hepatitis E virus infection in transplant recipients. N Engl J Med. 2014;370(12):1111–1120. doi:10.1056/NEJMoa121524624645943
  • EASL Clinical Practice Guidelines on hepatitis E virus infection. Journal of Hepatology. 2018;68(6):1256–1271. doi:10.1016/j.jhep.2018.03.00529609832
  • Vollmer T, Knabbe C, Dreier J. Comparison of real-time PCR and antigen assays for detection of hepatitis E virus in blood donors. J Clin Microbiol. 2014;52(6):2150–2156. doi:10.1128/JCM.03578-1324740079
  • Trémeaux P, Lhomme S, Chapuy-Regaud S, et al. Performance of an antigen assay for diagnosing acute hepatitis E virus genotype 3 infection. J Clin Virol. 2016;79:1–5. doi:10.1016/j.jcv.2016.03.01927038538
  • Al-Sadeq DW, Majdalawieh AF, Mesleh AG, Abdalla OM, Nasrallah GK. Laboratory challenges in the diagnosis of hepatitis E virus. J Med Microbiol. 2018;67(4):466–480. doi:10.1099/jmm.0.00070629485390
  • Stoszek SK, Abdel-Hamid M, Saleh DA, et al. High prevalence of hepatitis E antibodies in pregnant Egyptian women. Trans R Soc Trop Med Hyg. 2006;100(2):95–101. doi:10.1016/j.trstmh.2004.12.00516257426
  • Stoszek SK, Engle RE, Abdel-Hamid M, et al. Hepatitis E antibody seroconversion without disease in highly endemic rural Egyptian communities. Trans R Soc Trop Med Hyg. 2006;100(2):89–94. doi:10.1016/j.trstmh.2005.05.01916257427
  • Shata MT, Daef EA, Zaki ME, et al. Protective role of humoral immune responses during an outbreak of hepatitis E in Egypt. Trans R Soc Trop Med Hyg. 2012;106(10):613–618. doi:10.1016/j.trstmh.2012.07.00422938992
  • Sayed IM, Foquet L, Verhoye L, et al. Transmission of hepatitis E virus infection to human-liver chimeric FRG mice using patient plasma. Antiviral Res. 2017;141:150–154. doi:10.1016/j.antiviral.2017.02.01128232247
  • Sayed IM, Meuleman P. Murine tissues of human liver chimeric mice are not susceptible to Hepatitis E virus genotypes 1 and 3. J Infect Dis. 2017;216(7):919–920. doi:10.1093/infdis/jix42228968853
  • Sayed IM, Verhoye L, Cocquerel L, et al. Study of hepatitis E virus infection of genotype 1 and 3 in mice with humanised liver. Gut. 2017;66(5):920–929. doi:10.1136/gutjnl-2015-31110927006186
  • Sayed IM, Verhoye L, Montpellier C, et al. Study of hepatitis E virus ORF2 antigen kinetics in human-liver chimeric mice and its impact on HEV diagnosis. J Infect Dis. 2019;220(5):811–819. doi:10.1093/infdis/jiz17131001628
  • Sayed IM, Elkhawaga AA, El-Mokhtar MA. Circulation of hepatitis E virus (HEV) and/or HEV-like agent in non-mixed dairy farms could represent a potential source of infection for Egyptian people. Int J Food Microbiol. 2020;317:108479. doi:10.1016/j.ijfoodmicro.2019.10847931874303
  • El-Mokhtar MA, Elgendy SG, Eldin AS, et al. Hepatitis C virus affects tuberculosis-specific T cells in HIV-negative patients. Viruses. 2020;12:1. doi:10.3390/v12010101
  • Ali ME, El-Badawy O, Afifi NA, et al. Role of T-Helper 9 cells in chronic hepatitis C-infected patients. Viruses. 2018;10:7. doi:10.3390/v10070341
  • Hassan EA, Ahmed EH, Nafee AM, El-Gafary N, Hetta HF, El-Mokhtar MA. Regulatory T Cells, IL10 and IL6 in HCV related hepatocellular carcinoma after Transarterial Chemoembolization (TACE). Egypt j Immunol. 2019;26(1):69–78.31332997
  • Zakaria S, Fouad R, Shaker O, et al. Changing patterns of acute viral hepatitis at a major urban referral center in Egypt. Clin Infect Dis. 2007;44(4):e30–36. doi:10.1086/51107417243045
  • Divizia M, Gabrieli R, Stefanoni ML, et al. HAV and HEV infection in hospitalised hepatitis patients in Alexandria, Egypt. Eur J Epidemiol. 1999;15(7):603–609. doi:10.1023/A:100751403006210543349
  • Hasan G, Assiri A, Marzuuk N, et al. Incidence and characteristics of hepatitis E virus infection in children in Assiut, Upper Egypt. J Int Med Res. 2016;44(5):1115–1122. doi:10.1177/030006051665957527688687
  • Blackard JT, Rouster SD, Nady S, et al. Genotypic characterization of symptomatic hepatitis E virus (HEV) infections in Egypt. J Clin Virol. 2009;46(2):140–144. doi:10.1016/j.jcv.2009.07.00719651539
  • El-Mokhtar MA, Othman ER, Khashbah MY, et al. Evidence of the extrahepatic replication of Hepatitis E virus in human endometrial stromal cells. Pathogens. 2020;9:4. doi:10.3390/pathogens9040295
  • Sayed IM, Seddik MI, Gaber MA, Saber SH, Mandour SA, El-Mokhtar MA. Replication of Hepatitis E Virus (HEV) in primary human-derived monocytes and macrophages in vitro. Vaccines (Basel. 2020;8:2.
  • El-Mokhtar MA, Seddik MI, Osman A, et al. Hepatitis E virus mediates renal injury via the interaction between the immune cells and renal epithelium. Vaccines (Basel. 2020;8:3.
  • Eldin SS, Seddik I, Daef EA, et al. Risk factors and immune response to hepatitis E viral infection among acute hepatitis patients in Assiut, Egypt. Egypt j Immunol. 2010;17(1):73–86.22053611
  • Wallace SJ, Webb GW, Madden RG, et al. Investigation of liver dysfunction, who should we test for hepatitis E? European Journal of Gastroenterology & Hepatology. 2017;29(2):215–220. doi:10.1097/MEG.000000000000078127832041
  • Saravanabalaji S, Tripathy AS, Dhoot RR, Chadha MS, Kakrani AL, Arankalle VA. Viral load, antibody titers and recombinant open reading frame 2 protein-induced TH1/TH2 cytokines and cellular immune responses in self-limiting and fulminant hepatitis e. Intervirology. 2009;52(2):78–85. doi:10.1159/00021486219401616
  • Pischke S, Hartl J, Pas SD, Lohse AW, Jacobs BC, Van der Eijk AA. Hepatitis E virus, infection beyond the liver? J Hepatol. 2017;66(5):1082–1095. doi:10.1016/j.jhep.2016.11.01627913223
  • Suzuki K, Aikawa T, Okamoto H. Fulminant hepatitis E in Japan. N Engl J Med. 2002;347(18):1456. doi:10.1056/NEJM20021031347181912409557
  • Kar P, Jilani N, Husain SA, et al. Does hepatitis E viral load and genotypes influence the final outcome of acute liver failure during pregnancy? Am J Gastroenterol. 2008;103(10):2495–2501. doi:10.1111/j.1572-0241.2008.02032.x18785952
  • Chalupa P, Vasickova P, Pavlik I, Holub M. Endemic hepatitis E in the Czech Republic. Clin Infect Dis. 2014;58(4):509–516. doi:10.1093/cid/cit78224280093
  • Sayed IM, Elkhawaga AA, El-Mokhtar MA. In vivo models for studying Hepatitis E virus infection; Updates and applications. Virus Res. 2019;274:197765. doi:10.1016/j.virusres.2019.19776531563457
  • Manka P, Bechmann LP, Coombes JD, et al. Hepatitis E virus infection as a possible cause of acute liver failure in Europe. Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc. 2015;13(10):1836–1842.e1832; quiz e1157–1838. doi:10.1016/j.cgh.2015.04.014
  • Crossan CL, Simpson KJ, Craig DG, et al. Hepatitis E virus in patients with acute severe liver injury. World J Hepatol. 2014;6(6):426–434. doi:10.4254/wjh.v6.i6.42625018853
  • Chau TN, Lai ST, Tse C, et al. Epidemiology and clinical features of sporadic hepatitis E as compared with hepatitis A. Am J Gastroenterol. 2006;101(2):292–296. doi:10.1111/j.1572-0241.2006.00416.x16454833
  • Delarocque-Astagneau E, Abravanel F, Moshen A, et al. Epidemiological and virological characteristics of symptomatic acute hepatitis E in Greater Cairo, Egypt. Clin Microbiol Infect. 2012;18(10):982–988. doi:10.1111/j.1469-0691.2011.03727.x22264267
  • El-Mokhtar MA, Elkhawaga AA, Sayed IM. Assessment of hepatitis E virus (HEV) in the edible goat products pointed out a risk for human infection in Upper Egypt. Int J Food Microbiol. 2020;330:108784. doi:10.1016/j.ijfoodmicro.2020.10878432659521
  • Sayed IM, Hammam ARA. Enhancement of the molecular and serological assessment of Hepatitis E virus in milk samples. 2020;8:8.
  • Kumar M, Sharma BC, Sarin SK. Hepatitis E virus as an etiology of acute exacerbation of previously unrecognized asymptomatic patients with hepatitis B virus-related chronic liver disease. J Gastroenterol Hepatol. 2008;23(6):883–887. doi:10.1111/j.1440-1746.2007.05243.x18070014
  • López-Fabal MF, Gómez-Garcés JL. [Seroprevalence of hepatitis E virus in patients with hepatitis C and/or infected with HIV]. Revista Espanola De Quimioterapia, Publicacion Oficial De La Sociedad Espanola De Quimioterapia. 2015;28(6):314–316.26621176
  • Dalton HR, Fellows HJ, Stableforth W, et al. The role of hepatitis E virus testing in drug-induced liver injury. Aliment Pharmacol Ther. 2007;26(10):1429–1435. doi:10.1111/j.1365-2036.2007.03504.x17850420
  • Sayed IM, Vercouter AS, Meuleman P. Hepatitis E virus in acute liver failure, an unusual suspect? Hepatology (Baltimore, Md). 2016;64(6):1837–1839. doi:10.1002/hep.28759
  • Llovet LP, Gratacós-Ginés J, Ortiz O, Rodriguez-Tajes S. Higher seroprevalence of hepatitis E virus in autoimmune hepatitis, role of false-positive antibodies. 2020;40(3):558–564. doi:10.1111/liv.14332
  • Nasrallah GK, Al Absi ES, Ghandour R, et al. Seroprevalence of hepatitis E virus among blood donors in Qatar (2013-2016). Transfusion. 2017;57(7):1801–1807. doi:10.1111/trf.1411628453178
  • Abravanel F, Chapuy-Regaud S, Lhomme S, et al. Performance of two commercial assays for detecting hepatitis E virus RNA in acute or chronic infections. Journal of Clinical Microbiology. 2013;51(6):1913–1916. doi:10.1128/JCM.00661-1323515544
  • Aldisi RS, Elsidiq MS, Dargham SR, et al. Performance evaluation of four type-specific commercial assays for detection of herpes simplex virus type 1 antibodies in a Middle East and North Africa population. Journal of Clinical Virology. 2018;103:1–7. doi:10.1016/j.jcv.2018.03.01129597097