128
Views
5
CrossRef citations to date
0
Altmetric
Original Research

Clinical Molecular Epidemiology of Carbapenem-Resistant Klebsiella pneumoniae Among Pediatric Patients in Jiangsu Province, China

, , , , &
Pages 4627-4635 | Published online: 22 Dec 2020

References

  • Logan LK. Carbapenem-resistant enterobacteriaceae: an emerging problem in children. Clin Infect Dis. 2012;55(6):852–859. doi:10.1093/cid/cis54322700827
  • WHO publishes list of bacteria for which new antibiotics are urgently needed; 2017 Available from: https://www.who.int/news-room/detail/27-02-2017-who-publishes-list-of-bacteria-for-which-new-antibiotics-are-urgently-needed. Accessed 1217, 2020.
  • Guo Y, Hu FP, Zhu DM, et al. Antimicrobial resistance changes of carbapenem-resistant strains isolated from children. Zhonghua Er Ke Za Zhi. 2018;56(12):907–914. doi:10.3760/cma.j.issn.0578-1310.2018.12.00530518004
  • Zhang Y, Wang Q, Yin Y, et al. Epidemiology of carbapenem-resistant enterobacteriaceae infections: report from the China CRE network. Antimicrob Agents Chemother. 2018;62(2):e01882–17. doi:10.1128/AAC.01882-1729203488
  • Dong F, Lu J, Wang Y, et al. A five-year surveillance of carbapenemase-producing Klebsiella pneumoniae in a pediatric hospital in China reveals increased predominance of NDM-1. Biomed Environ Sci. 2017;30(8):562–569. doi:10.3967/bes2017.07528807096
  • Munoz-Price LS, Quinn JP. The spread of Klebsiella pneumoniae carbapenemases: a tale of strains, plasmids, and transposons. Clin Infect Dis. 2009;49(11):1739–1741. doi:10.1086/64807819886796
  • Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing. M100 -S28. Wayne, PA: CLSI; 2018.
  • Kahlmeter G, Brown D, Goldstein F, et al. European Committee on Antimicrobial Susceptibility Testing (EUCAST) technical notes on antimicrobial susceptibility testing. Clin Microbiol Infect. 2006;12(6):501–503. doi:10.1111/j.1469-0691.2006.01454.x16700696
  • Endimiani A, Carias LL, Hujer AM, et al. Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States. Antimicrob Agents Chemother. 2008;52(7):2680–2682. doi:10.1128/AAC.00158-0818426899
  • Yang J, Chen Y, Jia X, et al. Dissemination and characterization of NDM-1-producing acinetobacter pittii in an intensive care unit in China. Clin Microbiol Infect. 2012;18(12):E506–E13. doi:10.1111/1469-0691.1203523036089
  • Senda K, Arakawa Y, Ichiyama S, et al. PCR detection of metallo-beta-lactamase gene (blaIMP) in gram-negative rods resistant to broad-spectrum beta-lactams. J Clin Microbiol. 1996;34(12):2909–2913. doi:10.1128/JCM.34.12.2909-2913.19968940421
  • Tsakris A, Pournaras S, Woodford N, et al. Outbreak of infections caused by pseudomonas aeruginosa producing VIM-1 carbapenemase in Greece. J Clin Microbiol. 2000;38(3):1290–1292. doi:10.1128/JCM.38.3.1290-1292.200010699045
  • Poirel L, Héritier C, Tolün V, Nordmann P. Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniae. Antimicrob Agents Chemother. 2004;48(1):15–22. doi:10.1128/AAC.48.1.15-22.200414693513
  • Yu Y, Ji S, Chen Y, et al. Resistance of strains producing extended-spectrum β-lactamases and genotype distribution in China. J Infect. 2007;54(1):53–57. doi:10.1016/j.jinf.2006.01.01416533535
  • Pérez-Pérez FJ, Hanson ND. Detection of plasmid-mediated AmpC β-lactamase genes in clinical isolates by using multiplex PCR. J Clin Microbiol. 2002;40(6):2153–2162. doi:10.1128/JCM.40.6.2153-2162.200212037080
  • Antachopoulos C, Iosifidis E. Colistin use in neonates and children with infections due to carbapenem-resistant bacteria. Pediatr Infect Dis J. 2017;36(9):905–907. doi:10.1097/INF.000000000000165528650936
  • Quan J, Li X, Chen Y, et al. Prevalence of mcr-1 in escherichia coli and Klebsiella pneumoniae recovered from bloodstream infections in China: a multicentre longitudinal study. Lancet Infect Dis. 2017;17(4):400–410. doi:10.1016/S1473-3099(16)30528-X28139430
  • Wang Q, Wang X, Wang J, et al. Phenotypic and genotypic characterization of carbapenem-resistant Enterobacteriaceae: data from a longitudinal large-scale CRE study in China (2012–2016). Clin Infect Dis. 2018;67(suppl_2):S196–S205. doi:10.1093/cid/ciy66030423057
  • Andrade LN, Vitali L, Gaspar GG, Bellissimo-Rodrigues F, Martinez R, Darini AL. Expansion and evolution of a virulent, extensively drug-resistant (polymyxin B-resistant), QnrS1-, CTX-M-2-, and KPC-2-producing Klebsiella pneumoniae ST11 international high-risk clone. J Clin Microbiol. 2014;52(7):2530–2535. doi:10.1128/JCM.00088-1424808234
  • Zhu J, Sun L, Ding B, et al. Outbreak of NDM-1-producing Klebsiella pneumoniae ST76 and ST37 isolates in neonates. Eur J Clin Microbiol Infect Dis. 2016;35(4):611–618. doi:10.1007/s10096-016-2578-z26803822
  • Jin Y, Shao C, Li J, Fan H, Bai Y, Wang Y. Outbreak of multidrug resistant NDM-1-producing Klebsiella pneumoniae from a neonatal unit in Shandong Province, China. PLoS One. 2015;10(3):e0119571. doi:10.1371/journal.pone.011957125799421
  • Hornsey M, Phee L, Wareham DW. A novel variant, NDM-5, of the New Delhi metallo-β-lactamase in a multidrug-resistant escherichia coli ST648 isolate recovered from a patient in the United Kingdom. Antimicrob Agents Chemother. 2011;55(12):5952–5954. doi:10.1128/AAC.05108-1121930874
  • Rahman M, Shukla SK, Prasad KN, et al. Prevalence and molecular characterisation of New Delhi metallo-β-lactamases NDM-1, NDM-5, NDM-6 and NDM-7 in multidrug-resistant enterobacteriaceae from India. Int J Antimicrob Agents. 2014;44(1):30–37. doi:10.1016/j.ijantimicag.2014.03.00324831713
  • Kong Z, Cai R, Cheng C, et al. First reported nosocomial outbreak of NDM-5-producing Klebsiella pneumoniae in a neonatal unit in China. Infect Drug Resist. 2019;12:3557–3566. doi:10.2147/IDR.S21894531814744
  • Chiotos K, Hayes M, Gerber JS, Tamma PD. Treatment of carbapenem-resistant enterobacteriaceae infections in Children. J Pediatric Infect Dis Soc. 2020;9(1):56–66. doi:10.1093/jpids/piz08531872226
  • Tian D, Pan F, Wang C, Sun Y, Zhang H. Resistance phenotype and clinical molecular epidemiology of carbapenem-resistant Klebsiella pneumoniae among pediatric patients in Shanghai. Infect Drug Resist. 2018;11:1935. doi:10.2147/IDR.S17558430498365
  • Zhou J, Yang J, Hu F, Gao K, Sun J, Yang J. Clinical and molecular epidemiologic characteristics of ceftazidime/avibactam-resistant carbapenem-resistant Klebsiella pneumoniae in a neonatal intensive care unit in China. Infect Drug Resist. 2020;13:2571. doi:10.2147/IDR.S25692232801794
  • Gao H, Liu Y, Wang R, Wang Q, Jin L, Wang H. The transferability and evolution of NDM-1 and KPC-2 co-producing Klebsiella pneumoniae from clinical settings. EBioMedicine. 2020;51:102599. doi:10.1016/j.ebiom.2019.10259931911273