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Infection and Drug Resistance Volume 14, 2021 - Issue
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Review

Direct-on-Target Microdroplet Growth Assay Applications for Clinical Antimicrobial Susceptibility Testing

Rongrong Li1 Department of Clinical Laboratory, Hefei Hospital Affiliated to Anhui Medical University the Second People’s Hospital of Hefei City, Hefei, Anhui Province, People’s Republic of China
,
Hao Tang2 The Fourth Affiliated Hospital of Anhui Medical University Laboratory, Hefei, People’s Republic of China
,
Huaming Xu2 The Fourth Affiliated Hospital of Anhui Medical University Laboratory, Hefei, People’s Republic of China
,
Yingli Ren3 The Second Affiliated Hospital of Anhui Medical University Laboratory, Hefei, People’s Republic of China
,
Shujin Li1 Department of Clinical Laboratory, Hefei Hospital Affiliated to Anhui Medical University the Second People’s Hospital of Hefei City, Hefei, Anhui Province, People’s Republic of China
&
Jilu Shen2 The Fourth Affiliated Hospital of Anhui Medical University Laboratory, Hefei, People’s Republic of ChinaCorrespondence[email protected]
Pages 1423-1425 | Published online: 14 Apr 2021

References

  • Paul S, Singh P, Shamanth AS, Rudramurthy SM, Chakrabarti A, Ghosh AK. Rapid detection of fluconazole resistance in Candida tropicalis by MALDI-TOF MS. Med Mycol. 2018;56(2):234–241. doi:10.1093/mmy/myx04228992333
  • Oviaño M, Rodríguez-Martínez JM, Pascual Á, Bou G, Pascual Á, Bou G. Rapid detection of the plasmid-mediated quinolone resistance determinant AAC(6ʹ)-Ib-cr in Enterobacteriaceae by MALDI-TOF MS analysis. J Antimicrob Chemother. 2017;72(4):1074–1080. doi:10.1093/jac/dkw55228065892
  • Oviaño M, Bou G. Matrix-assisted laser desorption ionization-time of flight mass spectrometry for the rapid detection of antimicrobial resistance mechanisms and beyond. Clin Microbiol Rev. 2018;32(1):e00037–18. doi:10.1128/CMR.00037-1830487165
  • Neonakis IK, Spandidos DA. MALDI-TOF MS-based direct-on-target microdroplet growth assay: latest developments. Exp Ther Med. 2020;20(3):2555–2556. doi:10.3892/etm.2020.897632765747
  • Neonakis IK, Spandidos DA. MALDI-TOF mass spectrometry-based direct-on-target microdroplet growth assay: a novel assay for susceptibility testing and beyond. Future Microbiol. 2019;14(9):729–731. doi:10.2217/fmb-2019-010631271061
  • Idelevich EA, Sparbier K, Kostrzewa M, Becker K. Rapid detection of antibiotic resistance by MALDI-TOF mass spectrometry using a novel direct-on-target microdroplet growth assay. Clin Microbiol Infect. 2018;24(7):738–743. doi:10.1016/j.cmi.2017.10.01629079147
  • Neonakis IK, Spandidos DA. Detection of carbapenemase producers by matrix-assisted laser desorption-ionization time-of-flight mass spectrometry (MALDI-TOF MS). Eur J Clin Microbiol Infect Dis. 2019;38(10):1795–1801. doi:10.1007/s10096-019-03620-031254128
  • Shen J, Huang S, Zhou C, Bijie H, Guo W. Rapid differential diagnosis value of MALDI-TOF MS direct target plate microdrop growth method for carbapenem resistant Enterobacteriaceae. Chin Clin Med. 2020;27(04):549–553.
  • Horseman TS, Lustik MB, Fong KSK. Rapid qualitative antibiotic resistance characterization using VITEK MS. Diagn Microbiol Infect Dis. 2020;97(4):115093. doi:10.1016/j.diagmicrobio.2020.11509332569920
  • Nix ID, Idelevich EA, Storck LM, et al. Detection of methicillin resistance in Staphylococcus aureus from agar cultures and directly from positive blood cultures using MALDI-TOF mass spectrometry-based direct-on-target microdroplet growth assay. Front Microbiol. 2020;11:232. doi:10.3389/fmicb.2020.0023232117194
  • Idelevich EA, Storck LM, Sparbier K, Drews O, Kostrzewa M, Becker K. Rapid direct susceptibility testing from positive blood cultures by the matrix-assisted laser desorption ionization-time of flight mass spectrometry-based direct-on-target microdroplet growth assay. J Clin Microbiol. 2018;56(10):e00913–18. doi:10.1128/JCM.00913-1830093392
  • Correa-Martínez CL, Idelevich EA, Sparbier K, Kostrzewa M, Becker K. Rapid detection of extended-spectrum β-lactamases (ESBL) and AmpC β-lactamases in Enterobacterales: development of a screening panel using the MALDI-TOF MS-based direct-on-target microdroplet growth assay. Front Microbiol. 2019;10:13. doi:10.3389/fmicb.2019.0001330733710
  • EUCAST. Guidelines for detection of resistance mechanisms and specific resistances of clinical and/or epidemiological importance. The European Committee on Antimicrobial Susceptibility Testing. Version 2.0; 2017. Available from: https://www.eucast.org/resistance_mechanisms/. Accessed April 8, 2021.
  • Correa-Martínez CL, Idelevich EA, Sparbier K, Kuczius T, Kostrzewa M, Becker K. Development of a MALDI-TOF MS-based screening panel for accelerated differential detection of carbapenemases in Enterobacterales using the direct-on-target microdroplet growth assay. Sci Rep. 2020;10(1):4988. doi:10.1038/s41598-020-61890-732193431

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