Increased Expression of IL-10 in Peripheral Blood Mononuclear Cells Correlates with Negative Interferon-γ Release Assay Results in Culture-Confirmed Tuberculosis Patients

References

• World Health Organization. Global Tuberculosis Report 2020. Geneva: World Health Organization;2020. Licence: CC BY-NC-SA 3.0 IGO.
   Google Scholar
• FloydK, GlaziouP, ZumlaA, RaviglioneM. The global tuberculosis epidemic and progress in care, prevention, and research: an overview in year 3 of the end TB era. Lancet Respir Med. 2018;6(4):299–314. doi:10.1016/S2213-2600(18)30057-229595511
   PubMed Web of Science ®Google Scholar
• WangL, ZhangH, RuanY, et al. Tuberculosis prevalence in China, 1990–2010; a longitudinal analysis of national survey data. Lancet. 2014;383(9934):2057–2064. doi:10.1016/S0140-6736(13)62639-224650955
   PubMed Web of Science ®Google Scholar
• DuJ, ShuW, LiuY, et al. Development and validation of external quality assessment panels for mycobacterial culture testing to diagnose tuberculosis in China. Eur J Clin Microbiol Infect Dis. 2019;38(10):1961–1968. doi:10.1007/s10096-019-03634-831342215
   PubMed Web of Science ®Google Scholar
• WalzlG, McNerneyR, Du PlessisN, et al. Tuberculosis: advances and challenges in development of new diagnostics and biomarkers. Lancet Infect Dis. 2018;18(7):e199–e210. doi:10.1016/S1473-3099(18)30111-729580818
   PubMed Web of Science ®Google Scholar
• PaiM, ZwerlingA, MenziesD. Systematic review: t-cell-based assays for the diagnosis of latent tuberculosis infection: an update. Ann Intern Med. 2008;149(3):177–184. doi:10.7326/0003-4819-149-3-200808050-0024118593687
   PubMed Web of Science ®Google Scholar
• StephanC, WolfT, GoetschU, et al. Comparing QuantiFERON-tuberculosis gold, T-SPOT tuberculosis and tuberculin skin test in HIV-infected individuals from a low prevalence tuberculosis country. AIDS. 2008;22(18):2471–2479. doi:10.1097/QAD.0b013e328318841519005270
   PubMed Web of Science ®Google Scholar
• NicolMP, DaviesMA, WoodK, et al. Comparison of T-SPOT.TB assay and tuberculin skin test for the evaluation of young children at high risk for tuberculosis in a community setting. Pediatrics. 2009;123(1):38–43. doi:10.1542/peds.2008-061119117858
   PubMed Web of Science ®Google Scholar
• LingDI, PaiM, DavidsV, et al. Are interferon-gamma release assays useful for diagnosing active tuberculosis in a high-burden setting?Eur Respir J. 2011;38(3):649–656. doi:10.1183/09031936.0018161021349910
   PubMed Web of Science ®Google Scholar
• World Health Organization. Latent Tuberculosis Infection: Updated and Consolidated Guidelines for Programmatic Management. Geneva: World Health Organization; 2018.
   Google Scholar
• SesterM, SotgiuG, LangeC, et al. Interferon-gamma release assays for the diagnosis of active tuberculosis: a systematic review and meta-analysis. Eur Respir J. 2011;37(1):100–111. doi:10.1183/09031936.0011481020847080
   PubMed Web of Science ®Google Scholar
• YamasueM, KomiyaK, UsagawaY, et al. Factors associated with false negative interferon-gamma release assay results in patients with tuberculosis: a systematic review with meta-analysis. Sci Rep. 2020;10(1):1607. doi:10.1038/s41598-020-58459-932005930
   PubMed Web of Science ®Google Scholar
• GideonHP, PhuahJ, MyersAJ, et al. Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization. PLoS Pathog. 2015;11(1):e1004603. doi:10.1371/journal.ppat.100460325611466
   PubMed Web of Science ®Google Scholar
• SchroderK, HertzogPJ, RavasiT, HumeDA. Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol. 2004;75(2):163–189.14525967
   PubMed Web of Science ®Google Scholar
• Domingo-GonzalezR, PrinceO, CooperA, KhaderSA. Cytokines and chemokines in mycobacterium tuberculosis infection. Microbiol Spectr. 2016;4(5):4–5. doi:10.1128/microbiolspec.TBTB2-0018-2016
   Web of Science ®Google Scholar
• TanY, LiQ, WangQ, et al. Evaluation of the MTBDRplus 2.0 assay for the detection of multidrug resistance among persons with presumptive pulmonary TB in China. Sci Rep. 2017;7(1):3364. doi:10.1038/s41598-017-03473-728611407
   PubMed Web of Science ®Google Scholar
• Alhassan MohammedH, Saboor-YaraghiAA, VahediH, et al. Immunotherapeutic effects of beta-D mannuronic acid on IL-4, GATA3, IL-17 and RORC gene expression in the PBMC of patients with inflammatory bowel diseases. Iran J Allergy Asthma Immunol. 2018;17(4):308–317.30537794
   PubMed Web of Science ®Google Scholar
• ChungY, FuE, WangM. Crosstalk between Shh and TGF-beta signaling in cyclosporine-enhanced cell proliferation in human gingival fibroblasts. PLoS One. 2013;8(7):e70128. doi:10.1371/journal.pone.007012823922933
   PubMed Web of Science ®Google Scholar
• NguyenDT, TeeterLD, GravesJ, GravissEA. Characteristics associated with negative interferon-gamma release assay results in culture-confirmed tuberculosis patients, Texas, USA, 2013–2015. Emerg Infect Dis. 2018;24(3):534–540. doi:10.3201/eid2403.17163329460756
   PubMed Web of Science ®Google Scholar
• PanL, JiaH, LiuF, et al. Risk factors for false-negative T-SPOT.TB assay results in patients with pulmonary and extra-pulmonary TB. J Infect. 2015;70(4):367–380. doi:10.1016/j.jinf.2014.12.01825597825
   PubMed Web of Science ®Google Scholar
• BrooksDG, WalshKB, ElsaesserH, OldstoneMB. IL-10 directly suppresses CD4 but not CD8 T cell effector and memory responses following acute viral infection. Proc Natl Acad Sci USA. 2010;107(7):3018–3023. doi:10.1073/pnas.091450010720133700
   PubMed Web of Science ®Google Scholar
• BereshchenkoO, BruscoliS, RiccardiC. Glucocorticoids, sex hormones, and immunity. Front Immunol. 2018;9:1332. doi:10.3389/fimmu.2018.0133229946321
   PubMed Web of Science ®Google Scholar
• RichardsDF, FernandezM, CaulfieldJ, HawrylowiczCM. Glucocorticoids drive human CD8(+) T cell differentiation towards a phenotype with high IL-10 and reduced IL-4, IL-5 and IL-13 production. Eur J Immunol. 2000;30(8):2344–2354. doi:10.1002/1521-4141(2000)30:8<2344::AID-IMMU2344>3.0.CO;2-710940925
   PubMed Web of Science ®Google Scholar
• ZhouXX, LiuYL, ZhaiK, ShiHZ, TongZH. Body fluid interferon-gamma release assay for diagnosis of extrapulmonary tuberculosis in adults: a systematic review and meta-analysis. Sci Rep. 2015;5:15284. doi:10.1038/srep1528426503802
   PubMed Web of Science ®Google Scholar