Surgical Antibiotic Prophylaxis in an Era of Antibiotic Resistance: Common Resistant Bacteria and Wider Considerations for Practice

References

• O’Neill J. Tackling drug-resistant infections globally: final report and recommendations. Government of the United Kingdom; 2016.
   Google Scholar
• World Health Organization. World action plan on antimicrobial resistance; 2015.
   Google Scholar
• Ademe M, Girma F. Candida auris: from multidrug resistance to pan-resistant strains. Infect Drug Resist. 2020;13:1287–1294. doi:10.2147/IDR.S24986432440165
   PubMed Web of Science ®Google Scholar
• Cosgrove SE. The relationship between antimicrobial resistance and patient outcomes: mortality, length of hospital stay, and health care costs. Clin Infect Dis. 2006;42(Supp2):S82–S89. doi:10.1086/49940616355321
   PubMed Web of Science ®Google Scholar
• Prestinaci F, Pezzotti P, Pantosti A. Antimicrobial resistance: a global multifaceted phenomenon. Pathog Glob Health. 2015;109(7):309–318. doi:10.1179/2047773215Y.000000003026343252
   PubMed Web of Science ®Google Scholar
• Vikesland P, Garner E, Gupta S, Kang S, Maile-Moskowitz A, Zhu N. Differential drivers of antimicrobial resistance across the world. Acc Chem Res. 2019;52(4):916–924. doi:10.1021/acs.accounts.8b0064330848890
   PubMed Web of Science ®Google Scholar
• Birgand G, Castro-Sánchez E, Hansen S, et al. Comparison of governance approaches for the control of antimicrobial resistance: analysis of three European countries. Antimicrob Resist Infect Control. 2018;7(1):28. doi:10.1186/s13756-018-0321-529468055
   PubMed Web of Science ®Google Scholar
• Munckhof W. Antibiotics for surgical prophylaxis. Aust Prescr. 2005;28:38–40. doi:10.18773/austprescr.2005.030
   Google Scholar
• Raymond DP, Kuehnert MJ, Sawyer RG. Preventing antimicrobial-resistant bacterial infections in surgical patients. Surg Infect. 2002;3(4):375–385. doi:10.1089/109629602762539599
   Google Scholar
• Strathdee SA, Davies SC, Marcelin JR. Confronting antimicrobial resistance beyond the COVID-19 pandemic and the 2020 US election. Lancet. 2020;396(10257):1050–1053. doi:10.1016/S0140-6736(20)32063-833007218
   PubMed Web of Science ®Google Scholar
• Cassini A, Högberg LD, Plachouras D, et al. Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis. Lancet Infect Dis. 2019;19(1):56–66. doi:10.1016/S1473-3099(18)30605-430409683
   PubMed Web of Science ®Google Scholar
• Oldenkamp R, Schultsz C, Mancini E, Cappuccio A. Filling the gaps in the global prevalence map of clinical antimicrobial resistance. Proc Natl Acad Sci USA. 2021;118(1):e2013515118. doi:10.1073/pnas.201351511833372157
   PubMed Web of Science ®Google Scholar
• Sipahi OR. Economics of antibiotic resistance. Expert Rev Anti Infect Ther. 2008;6(4):523–539. doi:10.1586/14787210.6.4.52318662118
   PubMed Web of Science ®Google Scholar
• Hofer U. The cost of antimicrobial resistance. Nat Rev Microbiol. 2019;17(1):3. doi:10.1038/s41579-018-0125-x30467331
   PubMedGoogle Scholar
• Magill SS, Edwards JR, Bamberg W, et al. Multistate point-prevalence survey of health care–associated infections. N Engl J Med. 2014;370(13):1198–1208. doi:10.1056/NEJMoa130680124670166
   PubMed Web of Science ®Google Scholar
• Owens CD, Stoessel K. Surgical site infections: epidemiology, microbiology and prevention. J Hosp Infect. 2008;70(Suppl 2):3–10. doi:10.1016/S0195-6701(08)60017-119022115
   PubMed Web of Science ®Google Scholar
• World Health Organization. Protocol for surgical site infection surveillance with a focus on settings with limited resources; 2018.
   Google Scholar
• Centers for Disease Control and Prevention. Surgical site infection event. National Healthcare Safety Network; 2021:1–39.
   Google Scholar
• Bratzler DW, Dellinger EP, Olsen KM, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J Health-Syst Pharm. 2013;70(3):195–283. doi:10.2146/ajhp12056823327981
   PubMedGoogle Scholar
• Anderson DJ, Sexton DJ. Antimicrobial prophylaxis for prevention of surgical site infection in adults. Waltham, MA: UptoDate; 2021.
   Google Scholar
• Bhangu A, Ademuyiwa AO, Aguilera ML, et al. Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study. Lancet Infect Dis. 2018;18(5):516–525.29452941
   PubMed Web of Science ®Google Scholar
• Vincent J-L, Rello J, Marshall J, et al. International study of the prevalence and outcomes of infection in intensive care units. JAMA. 2009;302(21):2323–2329. doi:10.1001/jama.2009.175419952319
   PubMed Web of Science ®Google Scholar
• Călina D, Docea AO, Rosu L, et al. Antimicrobial resistance development following surgical site infections. Mol Med Rep. 2017;15(2):681–688. doi:10.3892/mmr.2016.603427959419
   PubMed Web of Science ®Google Scholar
• Ben-Ami R, Rodríguez-Baño J, Arslan H, et al. A multinational survey of risk factors for infection with extended-spectrum beta-lactamase-producing Enterobacteriaceae in nonhospitalized patients. Clin Infect Dis. 2009;49(5):682–690. doi:10.1086/60471319622043
   PubMed Web of Science ®Google Scholar
• Crader MF, Varacallo M. Preoperative antibiotic prophylaxis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021.
   Google Scholar
• Crawford T, Rodvold KA, Solomkin JS. Vancomycin for surgical prophylaxis? Clin Infect Dis. 2012;54(10):1474–1479. doi:10.1093/cid/cis02722328468
   PubMed Web of Science ®Google Scholar
• Korol E, Johnston K, Waser N, et al. A systematic review of risk factors associated with surgical site infections among surgical patients. PLoS One. 2013;8(12):e83743. doi:10.1371/journal.pone.008374324367612
   PubMed Web of Science ®Google Scholar
• Cheadle WG. Risk factors for surgical site infection. Surg Infect. 2006;7(Suppl 1):S7–S11. doi:10.1089/sur.2006.7.s1-7
   PubMedGoogle Scholar
• Biccard BM, Madiba TE, Kluyts HL, et al. Perioperative patient outcomes in the African surgical outcomes study: a 7-day prospective observational cohort study. Lancet. 2018;391(10130):1589–1598. doi:10.1016/S0140-6736(18)30001-129306587
   PubMed Web of Science ®Google Scholar
• Forrester JA, Koritsanszky LA, Amenu D, et al. Developing process maps as a tool for a surgical infection prevention quality improvement Initiative in resource-constrained settings. J Am Coll Surg. 2018;226(6):1103–1116.e1103. doi:10.1016/j.jamcollsurg.2018.03.02029574175
   PubMed Web of Science ®Google Scholar
• Holubar S. Antimicrobial stewardship in hospital settings. In: Hooper DC, editor. UpToDate. Waltham, MA: UpToDate; 2021.
   Google Scholar
• Bischoff P, Kubilay NZ, Allegranzi B, Egger M, Gastmeier P. Effect of laminar airflow ventilation on surgical site infections: a systematic review and meta-analysis. Lancet Infect Dis. 2017;17(5):553–561. doi:10.1016/S1473-3099(17)30059-228216243
   PubMed Web of Science ®Google Scholar
• Wenzel RP. Minimizing surgical-site infections. N Engl J Med. 2010;362(1):75–77. doi:10.1056/NEJMe090875320054050
   PubMed Web of Science ®Google Scholar
• Lowy FD. Staphylococcus aureus Infections. N Engl J Med. 1998;339(8):520–532. doi:10.1056/NEJM1998082033908069709046
   PubMed Web of Science ®Google Scholar
• Gern BH, Greninger AL, Weissman SJ, Stapp JR, Tao Y, Qin X. Continued in vitro cefazolin susceptibility in methicillin-susceptible Staphylococcus aureus. Ann Clin Microbiol Antimicrob. 2018;17(1):5. doi:10.1186/s12941-018-0257-x29463249
   PubMed Web of Science ®Google Scholar
• Stapleton PD, Taylor PW. Methicillin resistance in Staphylococcus aureus: mechanisms and modulation. Sci Prog. 2002;85(Pt 1):57–72. doi:10.3184/00368500278323887011969119
   PubMedGoogle Scholar
• Malabarba A, Nicas TI, Thompson RC. Structural modifications of glycopeptide antibiotics. Med Res Rev. 1997;17(1):69–137. doi:10.1002/(SICI)1098-1128(199701)17:1<69::AID-MED3>3.0.CO;2-R8979249
   PubMed Web of Science ®Google Scholar
• World Health Organization. Antimicrobial resistance: global report on surveillance. Geneva: World Health Organization; 2014.
   Google Scholar
• Centers for Disease Control and Prevention. Staphylococcus aureus resistant to vancomycin–United States, 2002. MMWR Morb Mortal Wkly Rep. 2002;51(26):565–567.12139181
   PubMedGoogle Scholar
• Centers for Disease Control and Prevention. Vancomycin-resistant Staphylococcus aureus–New York, 2004. MMWR Morb Mortal Wkly Rep. 2004;53(15):322–323.15103297
   PubMedGoogle Scholar
• World Health Organization. Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics, Geneva; 2017.
   Google Scholar
• Cong Y, Yang S, Rao X. Vancomycin resistant Staphylococcus aureus infections: a review of case updating and clinical features. J Adv Res. 2019;21:169–176. doi:10.1016/j.jare.2019.10.00532071785
   PubMed Web of Science ®Google Scholar
• McGuinness WA, Malachowa N, DeLeo FR. Vancomycin resistance in Staphylococcus aureus. Yale J Biol Med. 2017;90(2):269–281.28656013
   PubMed Web of Science ®Google Scholar
• Shariati A, Dadashi M, Moghadam MT, van Belkum A, Yaslianifard S, Darban-Sarokhalil D. Global prevalence and distribution of vancomycin resistant, vancomycin intermediate and heterogeneously vancomycin intermediate Staphylococcus aureus clinical isolates: a systematic review and meta-analysis. Sci Rep. 2020;10(1):12689. doi:10.1038/s41598-020-69058-z32728110
   PubMed Web of Science ®Google Scholar
• Saravolatz LD, Pawlak J, Johnson LB. In vitro susceptibilities and molecular analysis of vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus isolates. Clin Infect Dis. 2012;55(4):582–586. doi:10.1093/cid/cis49222615331
   PubMed Web of Science ®Google Scholar
• Cetinkaya Y, Falk P, Mayhall CG. Vancomycin-resistant enterococci. Clin Microbiol Rev. 2000;13(4):686–707. doi:10.1128/CMR.13.4.68611023964
   PubMed Web of Science ®Google Scholar
• Wisplinghoff H, Bischoff T, Tallent SM, Seifert H, Wenzel RP, Edmond MB. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin Infect Dis. 2004;39(3):309–317. doi:10.1086/42194615306996
   PubMed Web of Science ®Google Scholar
• Eliopoulos GM, Gold HS. Vancomycin-resistant Enterococci: mechanisms and clinical observations. Clin Infect Dis. 2001;33(2):210–219. doi:10.1086/32181511418881
   PubMed Web of Science ®Google Scholar
• Centers for Disease Prevention and Control. Antibiotic resistance threats in the United States; 2013.
   Google Scholar
• Remschmidt C, Schröder C, Behnke M, Gastmeier P, Geffers C, Kramer TS. Continuous increase of vancomycin resistance in enterococci causing nosocomial infections in Germany - 10 years of surveillance. Antimicrob Resist Infect Control. 2018;7:54. doi:10.1186/s13756-018-0353-x29760912
   PubMed Web of Science ®Google Scholar
• Bush K, Bradford PA. Interplay between β-lactamases and new β-lactamase inhibitors. Nat Rev Microbiol. 2019;17(5):295–306. doi:10.1038/s41579-019-0159-830837684
   PubMed Web of Science ®Google Scholar
• Bassetti M, Vena A, Croxatto A, Righi E, Guery B. How to manage Pseudomonas aeruginosa infections. Drugs Context. 2018;7:212527. doi:10.7573/dic.21252729872449
   PubMedGoogle Scholar
• Bush K. The ABCD’s of β-lactamase nomenclature. J Infect Chemother. 2013;19(4):549–559. doi:10.1007/s10156-013-0640-723828655
   PubMed Web of Science ®Google Scholar
• Bush K, Jacoby GA. Updated functional classification of β-lactamases. Antimicrob Agents Chemother. 2010;54(3):969–976. doi:10.1128/AAC.01009-0919995920
   PubMed Web of Science ®Google Scholar
• Page MI, Badarau A. The mechanisms of catalysis by metallo beta-lactamases. Bioinorg Chem Appl. 2008;2008:576297. doi:10.1155/2008/576297
   Web of Science ®Google Scholar
• Brem J, Cain R, Cahill S, et al. Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates. Nat Commun. 2016;7:12406. doi:10.1038/ncomms1240627499424
   PubMed Web of Science ®Google Scholar
• Iovleva A, Doi Y. Carbapenem-resistant Enterobacteriaceae. Clin Lab Med. 2017;37(2):303–315. doi:10.1016/j.cll.2017.01.00528457352
   PubMed Web of Science ®Google Scholar
• Jacoby GA. AmpC β-lactamases. Clin Microbiol Rev. 2009;22(1):161–182. doi:10.1128/CMR.00036-0819136439
   PubMed Web of Science ®Google Scholar
• Grover N, Sahni AK, Bhattacharya S. Therapeutic challenges of ESBLS and AmpC beta-lactamase producers in a tertiary care center. Med J Armed Forces India. 2013;69(1):4–10. doi:10.1016/j.mjafi.2012.02.00124532926
   PubMedGoogle Scholar
• Paterson DL, Bonomo RA. Extended-spectrum β-lactamases: a clinical update. Clin Microbiol Rev. 2005;18(4):657–686. doi:10.1128/CMR.18.4.657-686.200516223952
   PubMed Web of Science ®Google Scholar
• Lahiri SD, Johnstone MR, Ross PL, McLaughlin RE, Olivier NB, Alm RA. Avibactam and class C β-lactamases: mechanism of inhibition, conservation of the binding pocket, and implications for resistance. Antimicrob Agents Chemother. 2014;58(10):5704–5713. doi:10.1128/AAC.03057-1425022578
   PubMed Web of Science ®Google Scholar
• Drawz SM, Bonomo RA. Three decades of beta-lactamase inhibitors. Clin Microbiol Rev. 2010;23(1):160–201. doi:10.1128/CMR.00037-0920065329
   PubMed Web of Science ®Google Scholar
• Pilmis B, Cattoir V, Lecointe D, et al. Carriage of ESBL-producing Enterobacteriaceae in French hospitals: the PORTABLSE study. J Hosp Infect. 2018;98(3):247–252. doi:10.1016/j.jhin.2017.11.02229222035
   PubMed Web of Science ®Google Scholar
• Chen LF, Anderson DJ, Paterson DL. Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases (KPC) resistance. Infect Drug Resist. 2012;5:133–141. doi:10.2147/IDR.S2661323055754
   PubMedGoogle Scholar
• Arnold RS, Thom KA, Sharma S, Phillips M, Kristie Johnson J, Morgan DJ. Emergence of Klebsiella pneumoniae carbapenemase-producing bacteria. South Med J. 2011;104(1):40–45. doi:10.1097/SMJ.0b013e3181fd7d5a21119555
   PubMed Web of Science ®Google Scholar
• van Duin D, Doi Y. The global epidemiology of carbapenemase-producing Enterobacteriaceae. Virulence. 2017;8(4):460–469. doi:10.1080/21505594.2016.122234327593176
   PubMed Web of Science ®Google Scholar
• Pesesky MW, Hussain T, Wallace M, et al. KPC and NDM-1 genes in related Enterobacteriaceae strains and plasmids from Pakistan and the United States. Emerg Infect Dis. 2015;21(6):1034–1037. doi:10.3201/eid2106.14150425988236
   PubMed Web of Science ®Google Scholar
• Palzkill T. Structural and mechanistic basis for extended-spectrum drug-resistance mutations in altering the specificity of TEM, CTX-M, and KPC β-lactamases. Front Mol Biosci. 2018;5(16). doi:10.3389/fmolb.2018.00016
   Web of Science ®Google Scholar
• Bassetti M, Giacobbe DR, Giamarellou H, et al. Management of KPC-producing Klebsiella pneumoniae infections. Clin Microbiol Infect. 2018;24(2):133–144. doi:10.1016/j.cmi.2017.08.03028893689
   PubMed Web of Science ®Google Scholar
• Palzkill T. Metallo-β-lactamase structure and function. Ann N Y Acad Sci. 2013;1277:91–104. doi:10.1111/j.1749-6632.2012.06796.x23163348
   PubMed Web of Science ®Google Scholar
• Mojica MF, Bonomo RA, Fast W. B1-metallo-β-lactamases: where do we stand? Curr Drug Targets. 2016;17(9):1029–1050. doi:10.2174/138945011666615100110562226424398
   PubMed Web of Science ®Google Scholar
• Oliphant CM, Green GM. Quinolones: a comprehensive review. Am Fam Physician. 2002;65(3):455–464.11858629
   PubMed Web of Science ®Google Scholar
• Shandera KC, Thibault GP, Deshon GE. Efficacy of one dose fluoroquinolone before prostate biopsy. Urology. 1998;52(4):641–643. doi:10.1016/S0090-4295(98)00311-29763085
   PubMed Web of Science ®Google Scholar
• Ruiz J. Mechanisms of resistance to quinolones: target alterations, decreased accumulation and DNA gyrase protection. J Antimicrob Chemother. 2003;51(5):1109–1117. doi:10.1093/jac/dkg22212697644
   PubMed Web of Science ®Google Scholar
• Hooper DC, Jacoby GA. Mechanisms of drug resistance: quinolone resistance. Ann N Y Acad Sci. 2015;1354(1):12–31. doi:10.1111/nyas.1283026190223
   PubMed Web of Science ®Google Scholar
• Aldred KJ, Kerns RJ, Osheroff N. Mechanism of quinolone action and resistance. Biochemistry. 2014;53(10):1565–1574. doi:10.1021/bi500056424576155
   PubMed Web of Science ®Google Scholar
• Lautenbach E, Fishman NO, Bilker WB, et al. Risk factors for fluoroquinolone resistance in nosocomial Escherichia coli and Klebsiella pneumoniae infections. Arch Intern Med. 2002;162(21):2469–2477. doi:10.1001/archinte.162.21.246912437407
   PubMedGoogle Scholar
• Zhu D-M, Li Q-H, Shen Y, Zhang Q. Risk factors for quinolone-resistant Escherichia coli infection: a systematic review and meta-analysis. Antimicrob Resist Infec Control. 2020;9(1):11. doi:10.1186/s13756-019-0675-331938541
   PubMed Web of Science ®Google Scholar
• Rezazadeh M, Baghchesaraei H, Peymani A. Plasmid-mediated quinolone-resistance (qnr) genes in clinical isolates of Escherichia coli collected from several hospitals of Qazvin and Zanjan Provinces, Iran. Osong Public Health Res Perspect. 2016;7(5):307–312. doi:10.1016/j.phrp.2016.08.00327812489
   PubMedGoogle Scholar
• Robicsek A, Jacoby GA, Hooper DC. The worldwide emergence of plasmid-mediated quinolone resistance. Lancet Infect Dis. 2006;6(10):629–640. doi:10.1016/S1473-3099(06)70599-017008172
   PubMed Web of Science ®Google Scholar
• Kim ES, Hooper DC. Clinical importance and epidemiology of quinolone resistance. Infect Chemother. 2014;46(4):226–238. doi:10.3947/ic.2014.46.4.22625566402
   PubMedGoogle Scholar
• Phillips CJ, Gilchrist M, Cooke FJ, et al. Adherence to antibiotic guidelines and reported penicillin allergy: pooled cohort data on prescribing and allergy documentation from two English National Health Service (NHS) trusts. BMJ Open. 2019;9(2):e026624. doi:10.1136/bmjopen-2018-026624
   Web of Science ®Google Scholar
• Savic LC, Khan DA, Kopac P, et al. Management of a surgical patient with a label of penicillin allergy: narrative review and consensus recommendations. Br J Anaesth. 2019;123(1):e82–e94. doi:10.1016/j.bja.2019.01.02630916014
   PubMed Web of Science ®Google Scholar
• Blumenthal KG, Ryan EE, Li Y, Lee H, Kuhlen JL, Shenoy ES. The impact of a reported penicillin allergy on surgical site infection risk. Clin Infect Dis. 2018;66(3):329–336. doi:10.1093/cid/cix79429361015
   PubMed Web of Science ®Google Scholar
• Macy E, Contreras R. Health care use and serious infection prevalence associated with penicillin “allergy” in hospitalized patients: a cohort study. J Allergy Clin Immunol. 2014;133(3):790–796. doi:10.1016/j.jaci.2013.09.02124188976
   PubMed Web of Science ®Google Scholar
• Ponce B, Raines BT, Reed RD, Vick C, Richman J, Hawn M. Surgical site infection after arthroplasty: comparative effectiveness of prophylactic antibiotics: do surgical care improvement project guidelines need to be updated? J Bone Joint Surg Am. 2014;96(12):970–977. doi:10.2106/JBJS.M.0066324951731
   PubMed Web of Science ®Google Scholar
• Pool C, Kass J, Spivack J, et al. Increased surgical site infection rates following clindamycin use in head and neck free tissue transfer. Otolaryngol Head Neck Surg. 2016;154(2):272–278. doi:10.1177/019459981561712926573570
   PubMed Web of Science ®Google Scholar
• Dhopeshwarkar N, Sheikh A, Doan R, et al. Drug-induced anaphylaxis documented in electronic health records. J Allergy Clin Immunol Pract. 2019;7(1):103–111. doi:10.1016/j.jaip.2018.06.01029969686
   PubMed Web of Science ®Google Scholar
• Blumenthal KG, Shenoy ES, Varughese CA, Hurwitz S, Hooper DC, Banerji A. Impact of a clinical guideline for prescribing antibiotics to inpatients reporting penicillin or cephalosporin allergy. Ann Allergy, Asthma Immunol. 2015;115(4):294–300.e292. doi:10.1016/j.anai.2015.05.01126070805
   PubMed Web of Science ®Google Scholar
• Park M, Markus P, Matesic D, Li JT. Safety and effectiveness of a preoperative allergy clinic in decreasing vancomycin use in patients with a history of penicillin allergy. Ann Allergy Asthma Immunol. 2006;97(5):681–687. doi:10.1016/S1081-1206(10)61100-317165279
   PubMed Web of Science ®Google Scholar
• Hruby A, Hu FB. The epidemiology of obesity: a big picture. Pharmacoeconomics. 2015;33(7):673–689. doi:10.1007/s40273-014-0243-x25471927
   PubMed Web of Science ®Google Scholar
• Charani E, Gharbi M, Frost G, Drumright L, Holmes A. Antimicrobial therapy in obesity: a multicentre cross-sectional study. J Antimicrob Chemother. 2015;70(10):2906–2912. doi:10.1093/jac/dkv18926174720
   PubMed Web of Science ®Google Scholar
• Polso AK, Lassiter JL, Nagel JL. Impact of hospital guideline for weight-based antimicrobial dosing in morbidly obese adults and comprehensive literature review. J Clin Pharm Therap. 2014;39(6):584–608. doi:10.1111/jcpt.1220025203631
   PubMed Web of Science ®Google Scholar
• Janson B, Thursky K. Dosing of antibiotics in obesity. Curr Opin Infect Dis. 2012;25(6):634–649. doi:10.1097/QCO.0b013e328359a4c123041773
   PubMed Web of Science ®Google Scholar
• Chopra T, Zhao JJ, Alangaden G, Wood MH, Kaye KS. Preventing surgical site infections after bariatric surgery: value of perioperative antibiotic regimens. Expert Rev Pharmacoecon Outcomes Res. 2010;10(3):317–328. doi:10.1586/erp.10.2620545596
   PubMed Web of Science ®Google Scholar
• Meng L, Mui E, Holubar MK, Deresinski SC. Comprehensive guidance for antibiotic dosing in obese adults. Pharmacother. 2017;37(11):1415–1431. doi:10.1002/phar.2023
   PubMed Web of Science ®Google Scholar
• Branch-Elliman W, O’Brien W, Strymish J, Itani K, Wyatt C, Gupta K. Association of duration and type of surgical prophylaxis with antimicrobial-associated adverse events. JAMA Surg. 2019;154(7):590–598. doi:10.1001/jamasurg.2019.056931017647
   PubMed Web of Science ®Google Scholar
• Scher KS. Studies on the duration of antibiotic administration for surgical prophylaxis. Am Surg. 1997;63(1):59–62.8985073
   PubMed Web of Science ®Google Scholar
• Australian Commission on Safety and Quality in Health Care. Antimicrobial prescribing practice in Australian Hospitals: results of the 2019 Hospital National Antimicrobial Prescribing survey; 2021:1–45.
   Google Scholar
• Zelenitsky SA, Ariano RE, Harding GK, Silverman RE. Antibiotic pharmacodynamics in surgical prophylaxis: an association between intraoperative antibiotic concentrations and efficacy. Antimicrob Agents Chemother. 2002;46(9):3026–3030. doi:10.1128/AAC.46.9.3026-3030.200212183263
   PubMed Web of Science ®Google Scholar
• Naik BI, Roger C, Ikeda K, et al. Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trial. Br J Anaesth. 2017;118(6):876–882. doi:10.1093/bja/aex02628505360
   PubMed Web of Science ®Google Scholar
• Swoboda SM, Merz C, Kostuik J, Trentler B, Lipsett PA. Does intraoperative blood loss affect antibiotic serum and tissue concentrations? Arch Surg. 1996;131(11):1165–1171. doi:10.1001/archsurg.1996.014302300470098911256
   PubMedGoogle Scholar
• Zanetti G, Giardina R, Platt R. Intraoperative redosing of cefazolin and risk for surgical site infection in cardiac surgery. Emerg Infect Dis. 2001;7(5):828–831. doi:10.3201/eid0705.01750911791504
   PubMed Web of Science ®Google Scholar
• Costa AD. Assessment of operative times of multiple surgical specialties in a public university hospital. Einstein. 2017;15(2):200–205. doi:10.1590/s1679-45082017gs390228767919
   PubMedGoogle Scholar
• Markantonis SL, Kostopanagiotou G, Panidis D, Smirniotis V, Voros D. Effects of blood loss and fluid volume replacement on serum and tissue gentamicin concentrations during colorectal surgery. Clin Ther. 2004;26(2):271–281. doi:10.1016/S0149-2918(04)90025-215038949
   PubMed Web of Science ®Google Scholar
• Ben-Ami R, Schwaber MJ, Navon-Venezia S, et al. Influx of extended-spectrum β-lactamase—producing Enterobacteriaceae into the hospital. Clin Infect Dis. 2006;42(7):925–934. doi:10.1086/50093616511754
   PubMed Web of Science ®Google Scholar
• Bhattacharya S. Is screening patients for antibiotic-resistant bacteria justified in the Indian context? Indian J Med Microbiol. 2011;29(3):213–217. doi:10.4103/0255-0857.8390221860099
   PubMed Web of Science ®Google Scholar
• Saied T, Hafez SF, Kandeel A, et al. Antimicrobial stewardship to optimize the use of antimicrobials for surgical prophylaxis in Egypt: a multicenter pilot intervention study. Am J Infect Control. 2015;43(11):e67–e71. doi:10.1016/j.ajic.2015.07.00426315059
   PubMed Web of Science ®Google Scholar
• Berríos-Torres SI, Umscheid CA, Bratzler DW, et al. Centers for disease control and prevention guideline for the prevention of surgical site infection, 2017. JAMA Surg. 2017;152(8):784–791. doi:10.1001/jamasurg.2017.090428467526
   PubMed Web of Science ®Google Scholar
• Labricciosa FM, Sartelli M, Correia S, et al. Emergency surgeons’ perceptions and attitudes towards antibiotic prescribing and resistance: a worldwide cross-sectional survey. World J Emerg Surg. 2018;13(1):27. doi:10.1186/s13017-018-0190-529988647
   PubMed Web of Science ®Google Scholar
• Tan JA, Naik VN, Lingard L. Exploring obstacles to proper timing of prophylactic antibiotics for surgical site infections. Qual Saf Health Care. 2006;15(1):32–38. doi:10.1136/qshc.2004.01253416456207
   PubMedGoogle Scholar
• Abdel-Aziz A, El-Menyar A, Al-Thani H, et al. Adherence of surgeons to antimicrobial prophylaxis guidelines in a tertiary general hospital in a rapidly developing country. Adv Pharmaco Sci. 2013;2013:842593.
   Google Scholar
• Bedouch P, Labarère J, Chirpaz E, et al. Compliance with guidelines on antibiotic prophylaxis in total hip replacement surgery: results of a retrospective study of 416 patients in a teaching hospital. Infect Control Hosp Epidemiol. 2004;25(4):302–307. doi:10.1086/50239615108727
   PubMed Web of Science ®Google Scholar
• Bull AL, Russo PL, Friedman ND, Bennett NJ, Boardman CJ, Richards MJ. Compliance with surgical antibiotic prophylaxis – reporting from a statewide surveillance programme in Victoria, Australia. J Hosp Infect. 2006;63(2):140–147. doi:10.1016/j.jhin.2006.01.01816621135
   PubMed Web of Science ®Google Scholar
• Graham H, Vasireddy A, Nehra D. A national audit of antibiotic prophylaxis in elective laparoscopic cholecystectomy. Ann R Coll Surg Engl. 2014;96(5):377–380. doi:10.1308/003588414X1394618490068824992423
   PubMedGoogle Scholar
• Miliani K, L’Hériteau F, Astagneau P. Group obotINS. Non-compliance with recommendations for the practice of antibiotic prophylaxis and risk of surgical site infection: results of a multilevel analysis from the INCISO Surveillance Network. J Antimicrob Chemother. 2009;64(6):1307–1315. doi:10.1093/jac/dkp36719837713
   PubMed Web of Science ®Google Scholar
• Mohamed Rizvi Z, Palasanthiran P, Wu C, Mostaghim M, McMullan B. Adherence to surgical antibiotic prophylaxis guidelines in children: a cohort study. J Paed Child Health. 2020;56(1):34–40. doi:10.1111/jpc.14484
   Web of Science ®Google Scholar
• Wright JD, Hassan K, Ananth CV, et al. Use of guideline-based antibiotic prophylaxis in women undergoing gynecologic surgery. Obstet Gynecol. 2013;122(6):1145–1153. doi:10.1097/AOG.0b013e3182a8a36a24201674
   PubMed Web of Science ®Google Scholar
• Romero Viamonte K, Salvent Tames A, Sepúlveda Correa R, Rojo Manteca MV, Martín-Suárez A. Compliance with antibiotic prophylaxis guidelines in caesarean delivery: a retrospective, drug utilization study (indication-prescription type) at an Ecuadorian hospital. Antimicrob Resist Infect Control. 2021;10(1):12. doi:10.1186/s13756-020-00843-133436096
   PubMedGoogle Scholar
• Hawkins RB, Levy SM, Senter CE, et al. Beyond surgical care improvement program compliance: antibiotic prophylaxis implementation gaps. Am J Surg. 2013;206(4):451–456. doi:10.1016/j.amjsurg.2013.02.00923809676
   PubMed Web of Science ®Google Scholar
• Haney V, Maman S, Prozesky J, Bezinover D, Karamchandani K. Improving intraoperative administration of surgical antimicrobial prophylaxis: a quality improvement report. BMJ Open Quality. 2020;9(3):e001042. doi:10.1136/bmjoq-2020-001042
   Google Scholar
• Mahmoudi L, Ghouchani M, Mahi-Birjand M, Bananzadeh A, Akbari A. Optimizing compliance with surgical antimicrobial prophylaxis guidelines in patients undergoing gastrointestinal surgery at a referral teaching hospital in southern Iran: clinical and economic impact. Infect Drug Resist. 2019;12:2437–2444. doi:10.2147/IDR.S21272831496756
   PubMed Web of Science ®Google Scholar
• Telfah S, Nazer L, Dirani M, Daoud F. Improvement in adherence to surgical antimicrobial prophylaxis guidelines after implementation of a multidisciplinary quality improvement project. Sultan Qaboos Univ Med J. 2015;15(4):e523–e527. doi:10.18295/squmj.2015.15.04.01426629381
   PubMedGoogle Scholar
• Segala FV, Murri R, Taddei E, et al. Antibiotic appropriateness and adherence to local guidelines in perioperative prophylaxis: results from an antimicrobial stewardship intervention. Antimicrob Resist Infect Control. 2020;9(1):164. doi:10.1186/s13756-020-00814-633106190
   PubMedGoogle Scholar
• Cohen ME, Salmasian H, Li J, et al. Surgical antibiotic prophylaxis and risk for postoperative antibiotic-resistant infections. J Am Coll Surg. 2017;225(5):631–638.e633. doi:10.1016/j.jamcollsurg.2017.08.01029030239
   PubMedGoogle Scholar
• Ribed A, Monje B, García-González X, et al. Improving surgical antibiotic prophylaxis adherence and reducing hospital readmissions: a bundle of interventions including health information technologies. Eur J Hosp Pharm. 2020;27(4):237–242. doi:10.1136/ejhpharm-2018-00166632587084
   PubMedGoogle Scholar
• Pons-Busom M, Aguas-Compaired M, Delás J, Eguileor-Partearroyo B. Compliance with local guidelines for antibiotic prophylaxis in surgery. Infect Control Hosp Epidemiol. 2004;25(4):308–312. doi:10.1086/50239715108728
   PubMed Web of Science ®Google Scholar
• World Health Organization. World Health Alliance for Patient Safety. Implementation Manual: WHO Surgical Safety Checklist. 1st ed. Geneva: World Health Organization; 2008.
   Google Scholar
• Haynes AB, Weiser TG, Berry WR, et al. A surgical safety checklist to reduce morbidity and mortality in a global population. N Engl J Med. 2009;360(5):491–499. doi:10.1056/NEJMsa081011919144931
   PubMed Web of Science ®Google Scholar
• de Vries EN, Dijkstra L, Smorenburg SM, Meijer RP, Boermeester MA. The SURgical PAtient Safety System (SURPASS) checklist optimizes timing of antibiotic prophylaxis. Patient Saf Surg. 2010;4(1):6. doi:10.1186/1754-9493-4-620388204
   PubMedGoogle Scholar
• White MC, Peven K, Clancy O, et al. Implementation strategies and the uptake of the World Health Organization surgical safety checklist in low and middle income countries: a systematic review and meta-analysis. Ann Surg. 2021;273:6. doi:10.1097/SLA.0000000000003944
   Google Scholar
• White MC, Randall K, Ravelojaona VA, et al. Sustainability of using the WHO surgical safety checklist: a mixed-methods longitudinal evaluation following a nationwide blended educational implementation strategy in Madagascar. BMJ Glob Health. 2018;3(6):e001104. doi:10.1136/bmjgh-2018-001104
   PubMed Web of Science ®Google Scholar
• White MC, Daya L, Karel FKB, et al. Using the knowledge to action framework to describe a nationwide implementation of the WHO surgical safety checklist in cameroon. Anesth Analg. 2020;130(5):1425–1434. doi:10.1213/ANE.000000000000458631856007
   PubMedGoogle Scholar
• White MC, Randall K, Capo-Chichi NFE, et al. Implementation and evaluation of nationwide scale-up of the surgical safety checklist. Br J Surg. 2019;106(2):e91–e102. doi:10.1002/bjs.1103430620076
   PubMedGoogle Scholar
• White MC, Leather AJM, Sevdalis N, Healey A. Economic case for scale-up of the WHO surgical safety checklist at the national level in Sub-Saharan Africa. Ann Surg. 2020. doi:10.1097/SLA.0000000000004498
   Google Scholar
• Kavanagh KT, Calderon LE, Saman DM, Abusalem SK. The use of surveillance and preventative measures for methicillin-resistant Staphylococcus aureus infections in surgical patients. Antimicrob Resist Infect Control. 2014;3(1):18. doi:10.1186/2047-2994-3-1824847437
   PubMedGoogle Scholar
• Lee AS, Cooper BS, Malhotra-Kumar S, et al. Comparison of strategies to reduce meticillin-resistant Staphylococcus aureus rates in surgical patients: a controlled multicentre intervention trial. BMJ Open. 2013;3(9):e003126. doi:10.1136/bmjopen-2013-003126
   Google Scholar
• Saraswat MK, Magruder JT, Crawford TC, et al. Preoperative Staphylococcus aureus screening and targeted decolonization in cardiac surgery. Ann Thorac Surg. 2017;104(4):1349–1356. doi:10.1016/j.athoracsur.2017.03.01828577844
   PubMedGoogle Scholar
• World Health Organization. WHO surgical site infection prevention guidelines web appendix 4. Summary of a systematic review on screening for extended spectrum beta-lactamase and the impact on surgical antibiotic prophylaxis. Geneva; 2018.
   Google Scholar
• Dubinsky-Pertzov B, Temkin E, Harbarth S, et al. Carriage of extended-spectrum beta-lactamase-producing Enterobacteriaceae and the risk of surgical site infection after colorectal surgery: a prospective cohort study. Clin Infect Dis. 2019;68(10):1699–1704. doi:10.1093/cid/ciy76830204851
   PubMed Web of Science ®Google Scholar
• Bonkat G, Pilatz A, Wagenlehner F. Time to adapt our practice? The European commission has restricted the use of fluoroquinolones since March 2019. Eur Urol. 2019;76(3):273–275. doi:10.1016/j.eururo.2019.06.01131239078
   PubMed Web of Science ®Google Scholar
• Freitas DM, Moreira DM. Fosfomycin trometamol vs ciprofloxacin for antibiotic prophylaxis before transrectal ultrasonography-guided prostate biopsy: a meta-analysis of clinical studies. Arab J Urol. 2019;17(2):114–119. doi:10.1080/2090598X.2019.159263631285922
   PubMed Web of Science ®Google Scholar
• Guss J, Abuzeid WM, Doghramji L, Edelstein PH, Chiu AG. Fluoroquinolone-resistant Pseudomonas aeruginosa in chronic rhinosinusitis. Orl J Otorhinolaryngol Relat Spec. 2009;71(5):263–267. doi:10.1159/00024242819797934
   PubMedGoogle Scholar
• Bratzler DW, Houck PM. Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project. Am J Surg. 2005;189(4):395–404. doi:10.1016/j.amjsurg.2005.01.01515820449
   PubMed Web of Science ®Google Scholar
• Classen DC, Evans RS, Pestotnik SL, Horn SD, Menlove RL, Burke JP. The timing of prophylactic administration of antibiotics and the risk of surgical-wound infection. N Engl J Med. 1992;326(5):281–286. doi:10.1056/NEJM1992013032605011728731
   PubMed Web of Science ®Google Scholar
• de Jonge SW, Gans SL, Atema JJ, Solomkin JS, Dellinger PE, Boermeester MA. Timing of preoperative antibiotic prophylaxis in 54,552 patients and the risk of surgical site infection: a systematic review and meta-analysis. Medicine. 2017;96(29):e6903. doi:10.1097/MD.000000000000690328723736
   PubMed Web of Science ®Google Scholar
• Spencer S, Ipema H, Hartke P, et al. Intravenous push administration of antibiotics: literature and considerations. Hosp Pharm. 2018;53(3):157–169. doi:10.1177/001857871876025730147136
   PubMed Web of Science ®Google Scholar
• Lexicomp. Adult Drug Information Handbook. Waltham, MA; 2020.
   Google Scholar
• Knox MC, Edye M. Adherence to surgical antibiotic prophylaxis guidelines in New South Wales, Australia: identifying deficiencies and regression analysis of contributing factors. Surg Infect (Larchmt). 2016;17(2):203–209. doi:10.1089/sur.2015.19526588725
   PubMed Web of Science ®Google Scholar
• Zvonar RK, Bush P, Roth V. Practice changes to improve delivery of surgical antibiotic prophylaxis. Healthc Q. 2008;11(3):141–144. doi:10.12927/hcq.2008.1966418382176
   PubMedGoogle Scholar
• Charani E, Ahmad R, Rawson TM, Castro-Sanchèz E, Tarrant C, Holmes AH. The differences in antibiotic decision-making between acute surgical and acute medical teams: an ethnographic study of culture and team dynamics. Clin Infect Dis. 2019;69(1):12–20. doi:10.1093/cid/ciy84430445453
   PubMed Web of Science ®Google Scholar
• Charani E, Tarrant C, Moorthy K, Sevdalis N, Brennan L, Holmes AH. Understanding antibiotic decision making in surgery-a qualitative analysis. Clin Microbiol Infect. 2017;23(10):752–760. doi:10.1016/j.cmi.2017.03.01328341492
   PubMed Web of Science ®Google Scholar
• Charani E, Smith I, Skodvin B, et al. Investigating the cultural and contextual determinants of antimicrobial stewardship programmes across low-, middle- and high-income countries-a qualitative study. PLoS One. 2019;14(1):e0209847. doi:10.1371/journal.pone.020984730650099
   PubMed Web of Science ®Google Scholar
• Davey P, Marwick CA, Scott CL, et al. Interventions to improve antibiotic prescribing practices for hospital inpatients. Cochrane Database Syst Rev. 2017;2:CD003543.28178770
   PubMed Web of Science ®Google Scholar
• Singh S, Mendelson M, Surendran S, et al. Investigating infection management and antimicrobial stewardship in surgery: a qualitative study from India and South Africa. Clin Microbiol Infect. 2021;27(10):1455–1464. doi:10.1016/j.cmi.2020.12.01333422658
   PubMedGoogle Scholar
• Ierano C, Thursky K, Peel T, Rajkhowa A, Marshall C, Ayton D. Influences on surgical antimicrobial prophylaxis decision making by surgical craft groups, anaesthetists, pharmacists and nurses in public and private hospitals. PLoS One. 2019;14(11):e0225011. doi:10.1371/journal.pone.022501131725771
   PubMed Web of Science ®Google Scholar
• Charani E, Castro-Sanchez E, Sevdalis N, et al. Understanding the determinants of antimicrobial prescribing within hospitals: the role of “prescribing etiquette”. Clin Infect Dis. 2013;57(2):188–196. doi:10.1093/cid/cit21223572483
   PubMed Web of Science ®Google Scholar
• Charani E, de Barra E, Rawson TM, et al. Antibiotic prescribing in general medical and surgical specialties: a prospective cohort study. Antimicrob Resist Infect Control. 2019;8:151. doi:10.1186/s13756-019-0603-631528337
   PubMedGoogle Scholar
• de Jonge SW, Boldingh QJJ, Solomkin JS, et al. Effect of postoperative continuation of antibiotic prophylaxis on the incidence of surgical site infection: a systematic review and meta-analysis. Lancet Infect Dis. 2020;20(10):1182–1192. doi:10.1016/S1473-3099(20)30084-032470329
   PubMed Web of Science ®Google Scholar
• Bonaconsa C, Mbamalu O, Mendelson M, et al. Visual mapping of team dynamics and communication patterns on surgical ward rounds: an ethnographic study. BMJ Qual Saf. 2021;30:812–824. doi:10.1136/bmjqs-2020-012372
   Google Scholar
• Anahtar MN, Yang JH, Kanjilal S, McAdam AJ. Applications of machine learning to the problem of antimicrobial resistance: an emerging model for translational research. J Clin Microbiol. 2021;59(7):e01260–01220. doi:10.1128/JCM.01260-20
   Web of Science ®Google Scholar
• Feretzakis G, Loupelis E, Sakagianni A, et al. Using machine learning techniques to aid empirical antibiotic therapy decisions in the intensive care unit of a general hospital in Greece. Antibiotics. 2020;9(2):50. doi:10.3390/antibiotics9020050
   Google Scholar
• Luong T, Salabarria AC, Roach DR. Phage therapy in the resistance era: where do we Stand and where are we going? Clin Ther. 2020;42(9):1659–1680. doi:10.1016/j.clinthera.2020.07.01432883528
   PubMed Web of Science ®Google Scholar
• Rubalskii E, Ruemke S, Salmoukas C, et al. Bacteriophage therapy for critical infections related to cardiothoracic surgery. Antibiotics. 2020;9(5):232. doi:10.3390/antibiotics9050232
   Google Scholar
• Brives C, Pourraz J. Phage therapy as a potential solution in the fight against AMR: obstacles and possible futures. Palgrave Commun. 2020;6(1):100. doi:10.1057/s41599-020-0478-4
   Web of Science ®Google Scholar
• Narasimhaiah MH, Asrani JY, Palaniswamy SM, et al. Therapeutic potential of Staphylococcal bacteriophages for nasal decolonization of Staphylococcus aureus in Mice. Adv Microbiol. 2013;03(01):9. doi:10.4236/aim.2013.31008
   Google Scholar
• Rohlke F, Stollman N. Fecal microbiota transplantation in relapsing Clostridium difficile infection. Therap Adv Gastroenterol. 2012;5(6):403–420. doi:10.1177/1756283X12453637
   PubMed Web of Science ®Google Scholar
• Gargiullo L, Del Chierico F, D’Argenio P, Putignani L. Gut Microbiota modulation for multidrug-resistant organism decolonization: present and future perspectives. Front Microbiol. 2019;10:1704. doi:10.3389/fmicb.2019.0170431402904
   PubMed Web of Science ®Google Scholar
• Tavoukjian V. Faecal microbiota transplantation for the decolonization of antibiotic-resistant bacteria in the gut: a systematic review and meta-analysis. J Hosp Infect. 2019;102(2):174–188. doi:10.1016/j.jhin.2019.03.01030926290
   PubMed Web of Science ®Google Scholar
• Paskovaty A, Pflomm JM, Myke N, Seo SK. A multidisciplinary approach to antimicrobial stewardship: evolution into the 21st century. Int J Antimicrob Agents. 2005;25(1):1–10. doi:10.1016/j.ijantimicag.2004.09.00115620820
   PubMed Web of Science ®Google Scholar