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Original Research

Differentiating Lower Extremity Necrotizing Soft Tissue Infection from Severe Cellulitis by Laboratory Parameters and Relevant History Points

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Pages 3563-3569 | Published online: 02 Sep 2021

References

  • WongC-H, ChangH-C, PasupathyS, KhinL-W, TanJ-L, LowC-O. Necrotizing fasciitis: clinical presentation, microbiology, and determinants of mortality. J Bone Joint Surg Am. 2003;85–A:1454–60.
  • AnayaDA, McMahonK, NathensAB, SullivanSR, FoyH, BulgerE. Predictors of mortality and limb loss in necrotizing soft tissue infections. Arch Surg Chic Ill 1960. 2005;140(2):151–157; discussion 158. doi:10.1001/archsurg.140.2.151
  • WongC-H, ChangH-C, PasupathyS, KhinL-W, TanJ-L, LowC-O. Necrotizing fasciitis: clinical presentation, microbiology, and determinants of mortality. J Bone Joint Surg Am. 2003;85(8):1454–1460. doi:10.2106/00004623-200308000-0000512925624
  • MajeskiJA, AlexanderJW. Early diagnosis, nutritional support, and immediate extensive debridement improve survival in necrotizing fasciitis. Am J Surg. 1983;145(6):784–787. doi:10.1016/0002-9610(83)90140-X6344676
  • LeeA, MayA, ObremskeyWT. Necrotizing soft-tissue infections: an orthopaedic emergency. J Am Acad Orthop Surg. 2019;27(5):e199–e206. doi:10.5435/JAAOS-D-17-0061630431504
  • AnayaDA, DellingerEP. Necrotizing soft-tissue infection: diagnosis and management. Clin Infect Dis. 2007;44(5):705–710. doi:10.1086/51163817278065
  • AvalahalliMG, MunirajaPK, KhalidMS, KaverappaK, DevarajL, RaoA. Comparative study of LRINEC score: procalcitonin and lrinec score: c-reactive protein in predicting duration of hospital stay and severity in necrotizing fasciitis. J Evol Med Dent Sci. 2016;5(51):3248. doi:10.14260/jemds/2016/754
  • TavilogluK, YanarH. Necrotizing fasciitis: strategies for diagnosis and management. World J Emerg Surg WJES. 2007;2(1):19. doi:10.1186/1749-7922-2-1917683625
  • WongC-H, KhinL-W, HengK-S, TanK-C, LowC-O. The LRINEC (laboratory risk indicator for necrotizing fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections. Crit Care Med. 2004;32(7):1535–1541. doi:10.1097/01.ccm.0000129486.35458.7d15241098
  • TanJ, KohB, HongC, et al. A comparison of necrotising fasciitis in diabetics and non-diabetics: a review of 127 patients. Bone Joint J. 2016;11(11):1563–1568. doi:10.1302/0301-620X.98B11.37526
  • HollandMJ. Application of the Laboratory Risk Indicator in Necrotising Fasciitis (LRINEC) score to patients in a tropical tertiary referral centre. Anaesth Intensive Care. 2009;37(4):588–592. doi:10.1177/0310057X090370041619681416
  • AbdullahM, McWilliamsB, KhanSU. Reliability of the Laboratory Risk Indicator in Necrotising Fasciitis (LRINEC) score. Surgeon. 2019;17(5):309–318. doi:10.1016/j.surge.2018.08.00130166238
  • JohnsonL, CrisologoP, SivaganesanS, CaldwellC, HenningJ. Evaluation of the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score for detecting necrotizing soft tissue infections in patients with diabetes and lower extremity infection. Diabetes Res Clin Pract. 2020;171:108520. doi:10.1016/j.diabres.2020.10852033096188
  • HansenMB, RasmussenLS, SvenssonM, et al. Association between cytokine response, the LRINEC score and outcome in patients with necrotizing soft tissue infection: a Multicentre, Prospective Study. Sci Rep. 2017;7(1):42179. doi:10.1038/srep4217928176831
  • WiggenhauserPS, HoffmannTK. Comment on: “cervical necrotizing fasciitis—the value of the laboratory risk indicator for necrotizing fasciitis score as an indicative parameter. J Oral Maxillofac Surg. 2016;74(6):1104–1105. doi:10.1016/j.joms.2015.12.025
  • LiaoC-I, LeeY-K, SuY-C, ChuangC-H, WongC-H. Validation of the laboratory risk indicator for necrotizing fasciitis (LRINEC) score for early diagnosis of necrotizing fasciitis. Tzu Chi Med J. 2012;24(2):73–76. doi:10.1016/j.tcmj.2012.02.009
  • HsiaoCT, ChangCP, HuangTY, ChenYC, FannWC. Prospective validation of the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score for necrotizing fasciitis of the extremities. PLoS One. 2020;15(1):e0227748. doi:10.1371/journal.pone.022774831978094
  • WuH, LiuS, LiC, SongZ. Modified Laboratory Risk Indicator for Necrotizing Fasciitis (m-LRINEC) score system in diagnosing necrotizing fasciitis: a Nested Case–Control Study. Infect Drug Resist. 2021;14:2105–2112. doi:10.2147/IDR.S31332134113137
  • BakkerJ, NijstenMW, JansenTC. Clinical use of lactate monitoring in critically ill patients. Ann Intensive Care. 2013;3(1):12. doi:10.1186/2110-5820-3-1223663301
  • WuP-H, WuK-H, HsiaoC-T, WuS-R, ChangC-P. Utility of modified Laboratory Risk Indicator for Necrotizing Fasciitis (MLRINEC) score in distinguishing necrotizing from non-necrotizing soft tissue infections. World J Emerg Surg. 2021;16(1):26. doi:10.1186/s13017-021-00373-034039397
  • DanielsM, OberländerH, SchieferJ, et al. Lactate based scoring system in the diagnosis of necrotizing fasciitis. J Burn Care Res. 2021;irab148. doi:10.1093/jbcr/irab14834324681
  • JansenTC, van BommelJ, BakkerJ. Blood lactate monitoring in critically ill patients: a systematic health technology assessment. Crit Care Med. 2009;37(10):2827–2839. doi:10.1097/CCM.0b013e3181a9889919707124
  • ChangC-P, FannW-C, WuS-R, LinC-N, HsiaoC-T. Lactate on emergency department arrival as a predictor of in-hospital mortality in necrotizing fasciitis: a retrospective study. J Orthop Surg. 2019;14(1):73. doi:10.1186/s13018-019-1108-y
  • YaghoubianA, de VirgilioC, DauphineC, LewisRJ, LinM. Use of admission serum lactate and sodium levels to predict mortality in necrotizing soft-tissue infections. Arch Surg. 2007;142(9):840–846. doi:10.1001/archsurg.142.9.84017875838
  • WallaceHA, WaheedA, PereraTB. Necrotizing fasciitis. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2019.
  • DworkinMS, WestercampMD, ParkL, McintyreA. The epidemiology of necrotizing fasciitis including factors associated with death and amputation. Epidemiol Infect. 2009;137(11):1609–1614. doi:10.1017/S095026880900253219351432
  • KhamnuanP, ChongruksutW, JearwattanakanokK, PatumanondJ, YodluangfunS, TantraworasinA. Necrotizing fasciitis: risk factors of mortality. Risk Manag Healthc Policy. 2015;8:1–7. doi:10.2147/RMHP.S7769125733938
  • MositesE, ZulzT, BrudenD, et al. Risk for Invasive streptococcal infections among adults experiencing homelessness, Anchorage, Alaska, USA, 2002–2015. Emerg Infect Dis. 2019;25(10):1911–1918. doi:10.3201/eid2510.181408
  • BruunT, OppegaardO, KittangBR, MylvaganamH, LangelandN, SkredeS. Etiology of cellulitis and clinical prediction of streptococcal disease: a Prospective Study. Open Forum Infect Dis. 2015;3:1. doi:10.1093/ofid/ofv181
  • Ellis SimonsenSM, Van OrmanER, HatchBE, et al. Cellulitis incidence in a defined population. Epidemiol Infect. 2006;134(2):293–299. doi:10.1017/S095026880500484X16490133
  • MisiakosEP, BagiasG, PatapisP, SotiropoulosD, KanavidisP, MachairasA. Current concepts in the management of necrotizing fasciitis. Front Surg. 2014;1:36. doi:10.3389/fsurg.2014.0003625593960
  • BorschitzT, SchlichtS, SiegelE, HankeE, von StebutE. Improvement of a clinical score for necrotizing fasciitis: ‘pain out of proportion’ and high CRP levels aid the diagnosis. PLoS One. 2015;10(7):e0132775. doi:10.1371/journal.pone.013277526196941