241
Views
2
CrossRef citations to date
0
Altmetric
Original Research

Appropriateness of Empirical Fluoroquinolones Therapy in Patients Infected with Escherichia coli, Klebsiella pneumoniae, or Pseudomonas aeruginosa: The Importance of the CLSI Breakpoints Revision

, ORCID Icon, &
Pages 3541-3552 | Published online: 31 Aug 2021

References

  • World Health Organization. Antimicrobial Resistance: Global Report on Surveillance 2014. Geneva, Switzerland: World Health Organization; 2014.
  • ZengS, XuZ, WangX, et al. Time series analysis of antibacterial usage and bacterial resistance in China: observations from a tertiary hospital from 2014 to 2018. Infect Drug Resist. 2019;12:2683–2691. doi:10.2147/IDR.S22018331695444
  • RoopeLSJ, SmithRD, PouwelsKB, et al. The challenge of antimicrobial resistance: what economics can contribute. Science. 2019;364(6435):eaau4679. doi:10.1126/science.aau467930948524
  • BolonMK. The newer fluoroquinolones. Infect Dis Clin North Am. 2009;23(4):1027–x. doi:10.1016/j.idc.2009.06.00319909896
  • EzelarabHAA, AbbasSH, HassanHA, Abuo-RahmaGEA. Recent updates of fluoroquinolones as antibacterial agents. Arch Pharm (Weinheim). 2018;351(9):e1800141. doi:10.1002/ardp.20180014130048015
  • LinderJA, HuangES, SteinmanMA, GonzalesR, StaffordRS. Fluoroquinolone prescribing in the United States: 1995 to 2002. Am J Med. 2005;118(3):259–268. doi:10.1016/j.amjmed.2004.09.01515745724
  • BaggsJ, FridkinSK, PollackLA, SrinivasanA, JerniganJA. Estimating national trends in inpatient antibiotic use among US hospitals from 2006 to 2012. JAMA Intern Med. 2016;176(11):1639–1648. doi:10.1001/jamainternmed.2016.565127653796
  • Centers for Disease Control and Prevention, US Department of Health and Human Services [Website on the Internet]. Antibiotic resistance threats in the United States. US; 2013. Available from: http://www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf. Accessed 820, 2021.
  • YangP, ChenY, JiangS, ShenP, LuX, XiaoY. Association between the rate of fluoroquinolones-resistant gram-negative bacteria and antibiotic consumption from China based on 145 tertiary hospitals data in 2014. BMC Infect Dis. 2020;20(1):269. doi:10.1186/s12879-020-04981-032264851
  • MutnickAH, RhombergPR, SaderHS, JonesRN. Antimicrobial usage and resistance trend relationships from the MYSTIC programme in North America (1999–2001). J Antimicrob Chemother. 2004;53(2):290–296. doi:10.1093/jac/dkh03914711839
  • KimB, KimY, HwangH, et al. Trends and correlation between antibiotic usage and resistance pattern among hospitalized patients at university hospitals in Korea, 2004 to 2012: a Nationwide Multicenter Study. Medicine (Baltimore). 2018;97(51):e13719. doi:10.1097/MD.000000000001371930572507
  • WeistK, HögbergLD. ECDC publishes 2015 surveillance data on antimicrobial resistance and antimicrobial consumption in Europe. Euro Surveill. 2016;21(46):30401. doi:10.2807/1560-7917.ES.2016.21.46.30399
  • U.S. Department of Health and Human Services. Antibiotic Resistance Threats in the United States, 2013. Centers for Disease Control and Prevention. 2013.
  • RhombergPR, JonesRN. Summary trends for the meropenem yearly susceptibility test information collection program: a 10-year experience in the United States (1999–2008). Diagn Microbiol Infect Dis. 2009;65(4):414–426. doi:10.1016/j.diagmicrobio.2009.08.02019833471
  • ReddyP. Empiric antibiotic therapy of nosocomial bacterial infections. Am J Ther. 2016;23(4):e982–e994. doi:10.1097/MJT.000000000000004224413366
  • MuscedereJG, ShorrAF, JiangX, DayA, HeylandDK; Canadian Critical Care Trials Group. The adequacy of timely empiric antibiotic therapy for ventilator-associated pneumonia: an important determinant of outcome. J Crit Care. 2012;27(3):322.e7–322.e14. doi:10.1016/j.jcrc.2011.09.004
  • Membrilla-FernándezE, Sancho-InsenserJJ, Girvent-MontllorM, Álvarez-lermaF, Sitges-SerraA; Secondary Peritonitis Spanish Study Group. Effect of initial empiric antibiotic therapy combined with control of the infection focus on the prognosis of patients with secondary peritonitis. Surg Infect (Larchmt). 2014;15(6):806–814. doi:10.1089/sur.2013.24025397738
  • FitzpatrickJM, BiswasJS, EdgeworthJD, et al. Gram-negative bacteraemia; a multi-centre prospective evaluation of empiric antibiotic therapy and outcome in English acute hospitals. Clin Microbiol Infect. 2016;22(3):244–251. doi:10.1016/j.cmi.2015.10.03426577143
  • AypakC, AltunsoyA, DüzgünN. Empiric antibiotic therapy in acute uncomplicated urinary tract infections and fluoroquinolone resistance: a Prospective Observational Study. Ann Clin Microbiol Antimicrob. 2009;8:27. doi:10.1186/1476-0711-8-2719852849
  • Castro-SánchezE, Bennasar-VenyM, SmithM, et al. European commission guidelines for the prudent use of antimicrobials in human health: a missed opportunity to embrace nursing participation in stewardship. Clin Microbiol Infect. 2018;24(8):914–915. doi:10.1016/j.cmi.2018.02.03029505878
  • World Health Organization. Laboratory leadership competency framework; 2019. Available from: https://apps.who.int/iris/handle/10665/311445. Accessed 820, 2021.
  • CuiY, LiuJ, ZhangX. Effects of laboratory capabilities on combating antimicrobial resistance, 2013–2016: a static model panel data analysis. J Glob Antimicrob Resist. 2019;19:116–121. doi:10.1016/j.jgar.2019.03.00730904685
  • VanTT, MinejimaE, ChiuCA, Butler-WuSM. Don’t get wound up: revised fluoroquinolone breakpoints for Enterobacteriaceae and Pseudomonas aeruginosa. J Clin Microbiol. 2019;57(7):e02072–18. doi:10.1128/JCM.02072-1831043468
  • Morency-PotvinP, SchwartzDN, WeinsteinRA. Antimicrobial stewardship: how the microbiology laboratory can right the ship. Clin Microbiol Rev. 2016;30(1):381–407. doi:10.1128/CMR.00066-1627974411
  • HeilEL, JohnsonJK. Impact of CLSI breakpoint changes on microbiology laboratories and antimicrobial stewardship programs. J Clin Microbiol. 2016;54(4):840–844. doi:10.1128/JCM.02424-1526791363
  • GinocchioCC. Role of NCCLS in antimicrobial susceptibility testing and monitoring. Am J Health Syst Pharm. 2002;59(8 Suppl 3):S7–S11. doi:10.1093/ajhp/59.suppl_3.S7
  • CLSI. Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Ninth Informational Supplement. CLSI document M100-S29. Wayne: Clinical and Laboratory Standards Institute; 2019.
  • CLSI. Performance Standards for Antimicrobial Susceptibility Testing; 28th Informational Supplement. CLSI document M100-S28. Wayne: Clinical and Laboratory Standards Institute; 2018.
  • CLSI. Performance Standards for Antimicrobial Susceptibility Testing. 27th informational supplement M100-S27. Wayne: Clinical and Laboratory Standards Institute. 2017.
  • TsengYT, ChuangYC, ShuCC, HungCC, HsuCF, WangJY. Empirical use of fluoroquinolones improves the survival of critically ill patients with tuberculosis mimicking severe pneumonia. Crit Care. 2012;16(5):R207. doi:10.1186/cc1183923098258
  • ChenCH, WuB, TongHC. Analysis on drug resistance of pathogens and empiric medication in urinary tract infections. Mod Med J. 2015;43(2):173–176. In Chinese.
  • WarrenJW, AbrutynE, HebelJR, JohnsonJR, SchaefferAJ, StammWE. Guidelines for antimicrobial treatment of uncomplicated acute bacterial cystitis and acute pyelonephritis in women. Infectious Diseases Society of America (IDSA). Clin Infect Dis. 1999;29(4):745–758. doi:10.1086/52042710589881
  • GrossmanC, KellerN, BornsteinG, Ben-ZviI, Koren-MoragN, RahavG. Factors associated with suitability of empiric antibiotic therapy in hospitalized patients with bloodstream infections. J Chemother. 2017;29(3):159–163. doi:10.1080/1120009X.2016.118277027352218
  • HsuDI, OkamotoMP, MurthyR, Wong-BeringerA. Fluoroquinolone-resistant Pseudomonas aeruginosa: risk factors for acquisition and impact on outcomes. J Antimicrob Chemother. 2005;55(4):535–541. doi:10.1093/jac/dki02615728150
  • LiuPY, ShiZY, TungKC, et al. Antimicrobial resistance to cefotaxime and ertapenem in Enterobacteriaceae: the effects of altering clinical breakpoints. J Infect Dev Ctries. 2014;8(3):289–296. doi:10.3855/jidc.333524619258
  • ChuYW, TseH, TsangD. Adoption of the new CLSI fluoroquinolone breakpoints for Enterobacteriaceae. J Clin Microbiol. 2019;57(11):e01176–19. doi:10.1128/JCM.01176-1931645411
  • BolonMK, WrightSB, GoldHS, CarmeliY. The magnitude of the association between fluoroquinolone use and quinolone-resistant Escherichia coli and Klebsiella pneumoniae may be lower than previously reported. Antimicrob Agents Chemother. 2004;48(6):1934–1940. doi:10.1128/AAC.48.6.1934-1940.200415155181
  • DurhamLK, GeM, CucciaAJ, QuinnJP. Modeling antibiotic resistance to project future rates: quinolone resistance in Escherichia coli. Eur J Clin Microbiol Infect Dis. 2010;29(3):353–356. doi:10.1007/s10096-009-0862-x20119677
  • BischoffS, WalterT, GerigkM, EbertM, VogelmannR. Empiric antibiotic therapy in urinary tract infection in patients with risk factors for antibiotic resistance in a German emergency department. BMC Infect Dis. 2018;18(1):56. doi:10.1186/s12879-018-2960-929373965
  • ArslanH, AzapOK, ErgönülO, TimurkaynakF; Urinary Tract Infection Study Group. Risk factors for ciprofloxacin resistance among Escherichia coli strains isolated from community-acquired urinary tract infections in Turkey. J Antimicrob Chemother. 2005;56(5):914–918. doi:10.1093/jac/dki34416174685
  • AzapOK, ArslanH, SerefhanoğluK, et al. Risk factors for extended-spectrum beta-lactamase positivity in uropathogenic Escherichia coli isolated from community-acquired urinary tract infections. Clin Microbiol Infect. 2010;16(2):147–151. doi:10.1111/j.1469-0691.2009.02941.x19689464
  • Al-ZahraniJ, Al DossariK, GabrAH, AhmedAF, Al ShahraniSA, Al-GhamdiS. Antimicrobial resistance patterns of Uropathogens isolated from adult women with acute uncomplicated cystitis. BMC Microbiol. 2019;19(1):237. doi:10.1186/s12866-019-1612-631666014
  • ZhangYY, WangF, WangZM, et al. The indications and rational use of quinolones in the treatment of infectious diseases: a consensus. Chin J Infect Chemother. 2009;9(02):81–88. ( In Chinese.)
  • KhaliqY, ZhanelGG. Fluoroquinolone-associated tendinopathy: a critical review of the literature. Clin Infect Dis. 2003;36(11):1404–1410. doi:10.1086/37507812766835
  • Zhong NS, Wan XR, Ma XJ, et al.Guidelines for the clinical application of antibacterial drugs. National health commission of the People’s Republic of China, national administration of traditional Chinese medicine, medical department of general logistics department. 2015. ( In Chinese).
  • DiamantisS, RiouxC, BonnalC, et al. Suitability of initial antibiotic therapy for the treatment of bloodstream infections and the potential role of antibiotic management teams in improving it. Eur J Clin Microbiol Infect Dis. 2012;31(7):1667–1671. doi:10.1007/s10096-011-1491-822134774
  • LeeCC, LeeCH, ChuangMC, HongMY, HsuHC, KoWC. Impact of inappropriate empirical antibiotic therapy on outcome of bacteremic adults visiting the ED. Am J Emerg Med. 2012;30(8):1447–1456. doi:10.1016/j.ajem.2011.11.01022205015
  • MosdellDM, MorrisDM, VolturaA, et al. Antibiotic treatment for surgical peritonitis. Ann Surg. 1991;214(5):543–549. doi:10.1097/00000658-199111000-000011953104
  • GuoN, XueW, TangD, DingJ, ZhaoB. Risk factors and outcomes of hospitalized patients with blood infections caused by multidrug-resistant Acinetobacter baumannii complex in a hospital of Northern China. Am J Infect Control. 2016;44(4):e37–e39. doi:10.1016/j.ajic.2015.11.01926804303