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Original Research

Undernutrition and Treatment Success in Drug-Resistant Tuberculosis in Uganda

ORCID Icon, , , &
Pages 3673-3681 | Published online: 09 Sep 2021

References

  • World Health Organization. Global tuberculosis report 2020. In: Global Tuberculosis Report 2020. World Health Organization; 2020.
  • UplekarM, WeilD, LonnrothK, et al. WHO’s new end TB strategy. Lancet. 2015;385(9979):1799–1801. doi:10.1016/S0140-6736(15)60570-025814376
  • ChaJ, ThwaitesGE, AshtonPM. An evaluation of progress towards the 2035 WHO end TB targets in 40 high burden countries. medRxiv. 2020. doi:10.1101/2020.10.02.20175307
  • KnightGM, McQuaidCF, DoddPJ, HoubenRMGJ. Global burden of latent multidrug-resistant tuberculosis: trends and estimates based on mathematical modelling. Lancet Infect Dis. 2019;19(8):903–912. doi:10.1016/S1473-3099(19)30307-X31281059
  • FelekeBE, FelekeTE, BiadglegneF. Nutritional status of tuberculosis patients, a comparative cross-sectional study. BMC Pulm Med. 2019;19(1):182. doi:10.1186/s12890-019-0953-031638950
  • WhiteLV, LeeN, MarinFP, SaludarNR, EdwardsT, CoxSE. Performance of alternative measures to body mass index in the assessment of moderate and severe under-nutrition among acutely unwell patients hospitalized in a TB ward in the Philippines: a cross-sectional study. PLoS One. 2019;14(5):e0215968. doi:10.1371/journal.pone.021596831095582
  • MusuengeBB, PodaGG, ChenP-C. Nutritional status of patients with tuberculosis and associated factors in the health centre region of Burkina Faso. Nutrients. 2020;12(9):2540. doi:10.3390/nu12092540
  • ChandrasekaranP, SaravananN, BethunaickanR, TripathyS. Malnutrition: modulator of immune responses in tuberculosis. Front Immunol. 2017;8:1316. doi:10.3389/fimmu.2017.0131629093710
  • AlebelA, DemantD, PetruckaP, SibbrittD. Effects of undernutrition on mortality and morbidity among adults living with HIV in sub-Saharan Africa: a systematic review and meta-analysis. BMC Infect Dis. 2021;21(1):1. doi:10.1186/s12879-020-05706-z33390160
  • CegielskiJP, ArabL, Cornoni-HuntleyJ. Nutritional risk factors for tuberculosis among adults in the United States, 1971–1992. Am J Epidemiol. 2012;176(5):409–422. doi:10.1093/aje/kws00722791739
  • SiZ-L, Kang-L-L, ShenX-B, ZhouY-Z. Adjuvant efficacy of nutrition support during pulmonary tuberculosis treating course: systematic review and meta-analysis. Chin Med J (Engl). 2015;128(23):3219–3230. doi:10.4103/0366-6999.17025526612299
  • CaiH, ChenL, YinC, et al. The effect of micro-nutrients on malnutrition, immunity and therapeutic effect in patients with pulmonary tuberculosis: a systematic review and meta‐analysis of randomised controlled trials. Tuberculosis. 2020;125:101994. doi:10.1016/j.tube.2020.10199433049436
  • ZhengY, MaA, WangQ, et al. Relation of leptin, ghrelin and inflammatory cytokines with body mass index in pulmonary tuberculosis patients with and without type 2 diabetes mellitus. PLoS One. 2013;8(11):e80122. doi:10.1371/journal.pone.008012224260344
  • WondmienehA, GedefawG, GetieA, DemisA. Prevalence of undernutrition among adult tuberculosis patients in Ethiopia: a systematic review and meta-analysis. J Clin Tuberc Other Mycobact Dis. 2020;22:100211. doi:10.1016/j.jctube.2020.100211.33458257
  • BhargavaA, ChatterjeeM, JainY, et al. Nutritional status of adult patients with pulmonary tuberculosis in rural central India and its association with mortality. PLoS One. 2013;8(10):e77979. doi:10.1371/journal.pone.007797924205052
  • SinhaP, LönnrothK, BhargavaA, et al. Food for thought: addressing undernutrition to end tuberculosis. Lancet Infect Dis. 2021. doi:10.1016/S1473-3099(20)30792-1
  • ParkH-O, KimS-H, MoonS-H, et al. Association between body mass index and sputum culture conversion among South Korean patients with multidrug resistant tuberculosis in a tuberculosis referral hospital. Infect Chemother. 2016;48(4):317–323. doi:10.3947/ic.2016.48.4.31727883374
  • CegielskiJP, KurbatovaE, van der WaltM, et al. Multidrug-resistant tuberculosis treatment outcomes in relation to treatment and initial versus acquired second-line drug resistance. Clin Infect Dis. 2016;62(4):418–430. doi:10.1093/cid/civ91026508515
  • MeressaD, HurtadoRM, AndrewsJR, et al. Achieving high treatment success for multidrug-resistant TB in Africa: initiation and scale-up of MDR TB care in Ethiopia–an observational cohort study. Thorax. 2015;70(12):1181–1188. doi:10.1136/thoraxjnl-2015-20737426506854
  • TangS, TanS, YaoL, et al. Risk factors for poor treatment outcomes in patients with MDR-TB and XDR-TB in China: retrospective multi-center investigation. PLoS One. 2013;8(12):e82943. doi:10.1371/journal.pone.008294324349402
  • KangYA, KimSY, JoKW, et al. Impact of diabetes on treatment outcomes and long-term survival in multidrug-resistant tuberculosis. Respiration. 2013;86(6):472–478. doi:10.1159/00034837423689646
  • SharmaN, KhannaA, ChandraS, et al. Trends & treatment outcomes of multidrug-resistant tuberculosis in Delhi, India (2009–2014): a retrospective record-based study. Indian J Med Res. 2020;151(6):598–603. doi:10.4103/ijmr.IJMR_1048_1832719234
  • KassaGM, TadesseA, GelawYA, et al. Predictors of mortality among multidrug-resistant tuberculosis patients in central Ethiopia: a retrospective follow-up study. Epidemiol Infect. 2020;148:e258. doi:10.1017/S0950268820002514
  • KwonYS, KimYH, SuhGY, et al. Treatment outcomes for HIV-uninfected patients with multidrug-resistant and extensively drug-resistant tuberculosis. Clin Infect Dis. 2008;47(4):496–502. doi:10.1086/59000518611154
  • BenovaL, FieldingK, GreigJ, et al. Association of BMI category change with TB treatment mortality in HIV-positive smear-negative and extrapulmonary TB patients in Myanmar and Zimbabwe. PLoS One. 2012;7(4):e35948. doi:10.1371/journal.pone.003594822545150
  • LeveriTH, LekuleI, MollelE, LyamuyaF, KilonzoK. Predictors of treatment outcomes among multidrug resistant tuberculosis patients in Tanzania. Tuberc Res Treat. 2019;2019:1–10. doi:10.1155/2019/3569018
  • WahidA, AhmadN, GhafoorA, et al. Effectiveness of shorter treatment regimen in multidrug-resistant tuberculosis patients in Pakistan: a multicenter retrospective record review. Am J Trop Med Hyg. 2021;104(5):1784–1791. doi:10.4269/ajtmh.20-1134
  • SchwœbelV, TrébucqA, KashongweZ, et al. Outcomes of a nine-month regimen for rifampicin-resistant tuberculosis up to 24 months after treatment completion in nine African countries. EClinicalMedicine. 2020;20:100268. doi:10.1016/j.eclinm.2020.10026832300732
  • MagassoubaAS, TouréAA, DialloBD, et al. Malnutrition prevalence and associated biochemical factors among drug-resistance tuberculosis (DR-TB) patients at key treatment sites in Conakry City, Republic of Guinea. Pan Afr Med J. 2021;38(279). doi:10.11604/pamj.2021.38.279.27270
  • WhitehouseER, PerrinN, LevittN, HillM, FarleyJE. Cardiovascular risk prevalence in South Africans with drug-resistant tuberculosis: a cross-sectional study. Int J Tuberc Lung Dis. 2019;23(5):587–593. doi:10.5588/ijtld.18.037431097067
  • NambiE. Prevalence and factors associated with malnutrition among adult Tuberculosis patients attending the national referral tuberculosis program clinic at Mulago Hospital; 2015. Available from: http://makir.mak.ac.ug/handle/10570/5691. Accessed 717, 2021.
  • World Health Organisation. WHO Global Lists of High Burden Countries for Tuberculosis (TB), TB/HIV and Multidrug/Rifampicin-Resistant TB (MDR/RR-TB), 2021–2025. World Health Organisation; 2021.
  • BalukuJB, NakazibweB, NalokaJ, et al. Treatment outcomes of drug resistant tuberculosis patients with multiple poor prognostic indicators in Uganda: a countrywide 5-year retrospective study. J Clin Tuberculos Other Mycobacter Dis. 2021;23:100221. doi:10.1016/j.jctube.2021.100221
  • KasoziS, KirirabwaNS, KimuliD, et al. Addressing the drug-resistant tuberculosis challenge through implementing a mixed model of care in Uganda. PLoS One. 2020;15(12):e0244451. doi:10.1371/journal.pone.024445133373997
  • BalukuJB, BongominF. Treatment outcomes of pregnant women with drug resistant tuberculosis in Uganda: a retrospective review of 18 cases. Int J Infect Dis. 2021;105:230–233. doi:10.1016/j.ijid.2021.02.03233610787
  • World Health Organization. Haemoglobin Concentrations for the Diagnosis of Anaemia and Assessment of Severity. World Health Organization; 2011.
  • BaileyKV, Ferro-LuzziA. Use of body mass index of adults in assessing individual and community nutritional status. Bull World Health Organ. 1995;73(5):673–680.8846494
  • World Health Organization. Definitions and Reporting Framework for Tuberculosis–2013 Revision. World Health Organization; 2013.
  • GroblerL, NagpalS, SudarsanamTD, SinclairD. Nutritional supplements for people being treated for active tuberculosis. Cochrane Database Syst Rev. 2016;(6). doi:10.1002/14651858.CD006086.pub4
  • DialloA, DialloBD, CamaraLM, et al. Different profiles of body mass index variation among patients with multidrug-resistant tuberculosis: a retrospective cohort study. BMC Infect Dis. 2020;20:315. doi:10.1186/s12879-020-05028-032345228
  • NarasimhanP, WoodJ, MacIntyreCR, MathaiD. Risk factors for tuberculosis. Pulm Med. 2013;2013:828939. doi:10.1155/2013/82893923476764
  • GelawY, GetanehZ, MelkuM. Anemia as a risk factor for tuberculosis: a systematic review and meta-analysis. Environ Health Prev Med. 2021;26(1):13. doi:10.1186/s12199-020-00931-z33485299
  • Valdez-MiramontesCE, MartínezLAT, Torres-JuárezF, et al. Nicotine modulates molecules of the innate immune response in epithelial cells and macrophages during infection with M. tuberculosis. Clin Exp Immunol. 2020;199(2):230–243. doi:10.1111/cei.1338831631328
  • O’LearySM, ColemanMM, ChewWM, et al. Cigarette smoking impairs human pulmonary immunity to Mycobacterium tuberculosis. Am J Respir Crit Care Med. 2014;190(12):1430–1436. doi:10.1164/rccm.201407-1385OC25390734
  • BalukuJ, MusaaziJ, MulwanaR, MugaboA, BongominF, KatagiraW. Prevalence and predictors of CD4+ T-lymphocytopenia among HIV-negative tuberculosis patients in Uganda. Res Rep Trop Med. 2020;11:45–51. doi:10.2147/RRTM.S25255032612406
  • MendonçaEB, SchmaltzCA, Sant’AnnaFM, et al. Anemia in tuberculosis cases: a biomarker of severity?PLoS One. 2021;16(2):e0245458. doi:10.1371/journal.pone.024545833529195
  • NaguTJ, SpiegelmanD, HertzmarkE, et al. Anemia at the initiation of tuberculosis therapy is associated with delayed sputum conversion among pulmonary tuberculosis patients in Dar-es-Salaam, Tanzania. PLoS One. 2014;9(3):e91229. doi:10.1371/journal.pone.009122924642636
  • ShangaseZP, Tsoka-GwegweniJM, EgbeCO. Barriers to smoking cessation among drug-resistant tuberculosis patients in South Africa. Ann Glob Health. 2017;83(3–4):501–508. doi:10.1016/j.aogh.2017.05.00729221522
  • HellaJ, CercamondiCI, MhimbiraF, et al. Anemia in tuberculosis cases and household controls from Tanzania: contribution of disease, coinfections, and the role of hepcidin. PLoS One. 2018;13(4):e0195985. doi:10.1371/journal.pone.019598529677205
  • DemittoFO, Araújo-PereiraM, SchmaltzCA, et al. Impact of persistent anemia on systemic inflammation and tuberculosis outcomes in persons living with HIV. Front Immunol. 2020;11:2465. doi:10.3389/fimmu.2020.588405
  • KliimanK, AltrajaA. Predictors of poor treatment outcome in multi- and extensively drug-resistant pulmonary TB. Eur Respir J. 2009;33(5):1085–1094. doi:10.1183/09031936.0015570819164345
  • AliMH, AlrasheedyAA, HassaliMA, KibuuleD, GodmanB. Predictors of multidrug-resistant tuberculosis (MDR-TB) in Sudan. Antibiotics (Basel). 2019;8(3):90. doi:10.3390/antibiotics8030090