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Original Research

Functional Insights of MraZ on the Pathogenicity of Staphylococcus aureus

, , , , , , , , & show all
Pages 4539-4551 | Published online: 02 Nov 2021

References

  • Otto M. Staphylococcus colonization of the skin and antimicrobial peptides. Expert Rev Dermatol. 2010;5(2):183–195. doi:10.1586/edm.10.620473345
  • Tong SY, Davis JS, Eichenberger E, Holland TL, Fowler VG. Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management. Clin Microbiol Rev. 2015;28(3):603–661. doi:10.1128/CMR.00134-1426016486
  • Tacconelli E, Tumbarello M, Cauda R. Staphylococcus aureus infections. N Engl J Med. 1998;339(27):2026–2027.
  • Centers for Disease Control and Prevention. Active bacterial core surveillance report, emerging infections program network, methicillin-resistant Staphylococcus aureus. 2014.
  • Dinges MM, Orwin PM, Schlievert PM. Exotoxins of Staphylococcus aureus. Clin Microbiol Rev. 2000;13(1):16–34, table of contents. doi:10.1128/CMR.13.1.1610627489
  • Risley AL, Loughman A, Cywes-Bentley C, Foster TJ, Lee JC. Capsular polysaccharide masks clumping factor A-mediated adherence of Staphylococcus aureus to fibrinogen and platelets. J Infect Dis. 2007;196(6):919–927. doi:10.1086/52093217703424
  • Thammavongsa V, Kim HK, Missiakas D, Schneewind O. Staphylococcal manipulation of host immune responses. Nat Rev Microbiol. 2015;13(9):529–543. doi:10.1038/nrmicro352126272408
  • Otto M. Staphylococcus aureus toxins. Curr Opin Microbiol. 2014;17:32–37. doi:10.1016/j.mib.2013.11.00424581690
  • Dickey SW, Cheung GYC, Otto M. Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance. Nat Rev Drug Discov. 2017;16(7):457–471. doi:10.1038/nrd.2017.2328337021
  • Rasko DA, Sperandio V. Anti-virulence strategies to combat bacteria-mediated disease. Nat Rev Drug Discov. 2010;9(2):117–128. doi:10.1038/nrd301320081869
  • Eraso JM, Markillie LM, Mitchell HD, Taylor RC, Orr G, Margolin W. The highly conserved MraZ protein is a transcriptional regulator in Escherichia coli. J Bacteriol. 2014;196(11):2053–2066. doi:10.1128/JB.01370-1324659771
  • Maeda T, Tanaka Y, Takemoto N, Hamamoto N, Inui M. RNase III mediated cleavage of the coding region of mraZ mRNA is required for efficient cell division in Corynebacterium glutamicum. Mol Microbiol. 2016;99(6):1149–1166. doi:10.1111/mmi.1329526713407
  • Trespidi G, Scoffone VC, Barbieri G, Riccardi G, Rossi ED, Buroni S. Molecular characterization of the Burkholderia cenocepacia dcw Operon and FtsZ Interactors as new targets for novel antimicrobial design. Antibiotics. 2020;9(12):841. doi:10.3390/antibiotics9120841
  • Bae T, Schneewind O. Allelic replacement in Staphylococcus aureus with inducible counter-selection. Plasmid. 2006;55(1):58–63. doi:10.1016/j.plasmid.2005.05.00516051359
  • Montgomery CP, Boyle-Vavra S, Roux A, Ebine K, Sonenshein AL, Daum RS. CodY deletion enhances in vivo virulence of community-associated methicillin-resistant Staphylococcus aureus clone USA300. Infect Immun. 2012;80(7):2382–2389. doi:10.1128/IAI.06172-1122526672
  • Collins LV, Kristian SA, Weidenmaier C, et al. Staphylococcus aureus strains lacking D-alanine modifications of teichoic acids are highly susceptible to human neutrophil killing and are virulence attenuated in mice. J Infect Dis. 2002;186(2):214–219. doi:10.1086/34145412134257
  • Farnsworth CW, Schott EM, Jensen SE, et al. Adaptive upregulation of clumping factor A (ClfA) by Staphylococcus aureus in the obese, type 2 diabetic host mediates increased virulence. Infect Immun. 2017;85(6). doi:10.1128/IAI.01005-16.
  • Jenul C, Horswill AR, Fischetti VA. Regulation of Staphylococcus aureus virulence. Microbiol Spectr. 2019;7(2). doi:10.1128/microbiolspec.GPP3-0031-2018
  • Hua L, Hilliard JJ, Shi Y, et al. Assessment of an anti-alpha-toxin monoclonal antibody for prevention and treatment of Staphylococcus aureus-induced pneumonia. Antimicrob Agents Chemother. 2014;58(2):1108–1117. doi:10.1128/AAC.02190-1324295977
  • Wang Y, Di H, Chen F, et al. Discovery of benzocycloalkane derivatives efficiently blocking bacterial virulence for the treatment of methicillin-resistant S. aureus (MRSA) infections by targeting diapophytoene desaturase (CrtN). J Med Chem. 2016;59(10):4831–4848. doi:10.1021/acs.jmedchem.6b0012227139780
  • Chan WT, Espinosa M, Yeo CC. Keeping the wolves at bay: antitoxins of prokaryotic type II toxin-antitoxin systems. Front Mol Biosci. 2016;3:9. doi:10.3389/fmolb.2016.0000927047942
  • Dienemann C, Bøggild A, Winther KS, Gerdes K, Brodersen DE. Crystal structure of the VapBC toxin–antitoxin complex from Shigella flexneri reveals a hetero-octameric DNA-binding assembly. J Mol Biol. 2011;414(5):713–722. doi:10.1016/j.jmb.2011.10.02422037005
  • Kyuma T, Kimura S, Hanada Y, Suzuki T, Sekimizu K, Kaito C. Ribosomal RNA methyltransferases contribute to Staphylococcus aureus virulence. Febs J. 2015;282(13):2570–2584. doi:10.1111/febs.1330225893373
  • Vandenesch F, Lina G, Henry T. Staphylococcus aureus hemolysins, bi-component leukocidins, and cytolytic peptides: a redundant arsenal of membrane-damaging virulence factors? Front Cell Infect. 2012;2:12.
  • Cheung GYC, Bae JS, Otto M. Pathogenicity and virulence of Staphylococcus aureus. Virulence. 2021;12(1):547–569. doi:10.1080/21505594.2021.187868833522395
  • Jong NW, Kessel KP, Strijp JA. Immune evasion by Staphylococcus aureus. Microbiol Spectr. 2019;7(2):7–12.
  • Peschel A, Otto M, Jack RW, Kalbacher H, Jung G, Götz F. Inactivation of the dlt Operon inStaphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides. J Biol Chem. 1999;274(13):8405–8410. doi:10.1074/jbc.274.13.840510085071
  • Cheung GY, Wang R, Khan BA, Sturdevant DE, Otto M, Payne SM. Role of the accessory gene regulator agr in community-associated methicillin-resistant Staphylococcus aureus pathogenesis. Infect Immun. 2011;79(5):1927–1935. doi:10.1128/IAI.00046-1121402769
  • Zielinska AK, Beenken KE, Joo HS, et al. Defining the strain-dependent impact of the Staphylococcal accessory regulator (sarA) on the alpha-toxin phenotype of Staphylococcus aureus. J Bacteriol. 2011;193(12):2948–2958. doi:10.1128/JB.01517-1021478342