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Original Research

Vulvovaginitis Prevalence Among Women in Gondar, Northwest Ethiopia: Special Emphasis on Aerobic Vaginitis Causing Bacterial Profile, Antimicrobial Susceptibility Pattern, and Associated Factors

, ORCID Icon, ORCID Icon, & ORCID Icon
Pages 4567-4580 | Published online: 02 Nov 2021

References

  • Amabebe E, Anumba DOC. The vaginal microenvironment: the physiologic role of lactobacilli. Front Med. 2018;5:181. doi:10.3389/fmed.2018.00181
  • Sonthalia S, Aggarwal P, Das S, Sharma P, Sharma R, Singh S. Aerobic vaginitis - an underdiagnosed cause of vaginal discharge - narrative review. Int J STD AIDS. 2020;31(11):1018–1027. doi:10.1177/095646242091343532842907
  • Zhang T, Xue Y, Yue T, et al. Characteristics of aerobic vaginitis among women in Xi’an district: a hospital-based study. BMC Women's Health. 2020;20(1):138. doi:10.1186/s12905-020-00997-532605571
  • Donders GG, Vereecken A, Bosmans E, Dekeersmaecker A, Salembier G, Spitz B. Definition of a type of abnormal vaginal flora that is distinct from bacterial vaginosis: aerobic vaginitis. BJOG. 2002;109(1):34–43. doi:10.1111/j.1471-0528.2002.00432.x11845812
  • Kaambo E, Africa C, Chambuso R, Passmore JA. Vaginal microbiomes associated with aerobic vaginitis and bacterial vaginosis. Front Public Health. 2018;6:78. doi:10.3389/fpubh.2018.0007829632854
  • Donders G, Bellen G, Rezeberga D. Aerobic vaginitis in pregnancy. BJOG. 2011;118(10):1163–1170. doi:10.1111/j.1471-0528.2011.03020.x21668769
  • Kaambo E, Africa CWJ. The threat of aerobic vaginitis to pregnancy and neonatal morbidity. Afr J Reprod Health. 2017;21(2):108–118. doi:10.29063/ajrh2017/v21i2.1229624945
  • Vieira-Baptista P, Lima-Silva J, Pinto C, et al. Bacterial vaginosis, aerobic vaginitis, vaginal inflammation and major pap smear abnormalities. Eur J Clin Microbiol Infect Dis. 2016;35(4):657–664. doi:10.1007/s10096-016-2584-126810061
  • Hassan MF, Rund NMA, El-Tohamy O, et al. Does aerobic vaginitis have adverse pregnancy outcomes? Prospective Observational Study. Infect Dis Obstet Gynecol. 2020;2020:e5842150. doi:10.1155/2020/5842150
  • Villaseca R, Ovalle A, Amaya F, et al. [Vaginal infections in a family health clinic in the Metropolitan Region, Chile]. Rev Chilena Infectol. 2015;32(1):30–36. Spanish. doi:10.4067/S0716-1018201500020000525860041
  • Zodzika J, Rezeberga D, Jermakova I, Vasina O, Vedmedovska N, Donders G. Factors related to elevated vaginal pH in the first trimester of pregnancy. Acta Obstet Gynecol Scand. 2011;90(1):41–46. doi:10.1111/j.1600-0412.2010.01011.x21275914
  • Pacha-Herrera D, Vasco G, Cruz-Betancourt C, Galarza JM, Barragán V, Machado A. Vaginal microbiota evaluation and lactobacilli quantification by qPCR in pregnant and non-pregnant women: a Pilot Study. Front Cell Infect Microbiol. 2020;10:303. doi:10.3389/fcimb.2020.0030332637367
  • Mulu W, Yimer M, Zenebe Y, Abera B. Common causes of vaginal infections and antibiotic susceptibility of aerobic bacterial isolates in women of reproductive age attending at Felegehiwot Referral Hospital, Ethiopia: a cross sectional study. BMC Women's Health. 2015;15:42. doi:10.1186/s12905-015-0197-y25968607
  • Krauss-Silva L, Almada-Horta A, Alves MB, Camacho KG, Moreira MEL, Braga A. Basic vaginal pH, bacterial vaginosis and aerobic vaginitis: prevalence in early pregnancy and risk of spontaneous preterm delivery, a prospective study in a low socioeconomic and multiethnic South American population. BMC Pregnancy Childbirth. 2014;14:107. doi:10.1186/1471-2393-14-10724641730
  • Vieira-Baptista P, Bornstein J. Candidiasis, bacterial vaginosis, trichomoniasis and other vaginal conditions affecting the vulva. In: Vulvar Disease. Springer; 2019:167–205.
  • Yongjun T, Samuelson J, Qingsheng D, et al. The prevalence of sexually transmitted and other lower reproductive tract infections among rural women in Sichuan Province, China. Southeast Asian J Trop Med Public Health. 2009;40(5):1038–1047.19842387
  • Goldenberg RL, Klebanoff MA, Nugent R, Krohn MA, Hillier S, Andrews WW. Bacterial colonization of the vagina during pregnancy in four ethnic groups. Vaginal Infections and Prematurity Study Group. Am J Obstet Gynecol. 1996;174(5):1618–1621. doi:10.1016/S0002-9378(96)70617-89065140
  • Salinas AM, Osorio VG, Pacha-Herrera D, Vivanco JS, Trueba AF, Machado A. Vaginal microbiota evaluation and prevalence of key pathogens in Ecuadorian women: an epidemiologic analysis. Sci Rep. 2020;10(1):18358. doi:10.1038/s41598-020-74655-z33110095
  • Kenyon C, Colebunders R, Crucitti T. The global epidemiology of bacterial vaginosis: a systematic review. Am J Obstet Gynecol. 2013;209(6):505–523. doi:10.1016/j.ajog.2013.05.00623659989
  • Mengistie Z, Woldeamanuel Y, Asrat D, Yigeremu M. Comparison of clinical and gram stain diagnosis methods of bacterial vaginosis among pregnant women in Ethiopia. J Clin Diagn Res. 2013;7(12):2701–2703.24551617
  • Ayenalem S, Yusuf L, Ashenafi M. Lactic acid bacterial vaginosis among outpatients in Addis Ababa. Ethiop J Health Dev. 2010;24(3). doi:10.4314/ejhd.v24i3.68385
  • Mengistie Z, Woldeamanuel Y, Asrat D, Adera A. Prevalence of bacterial vaginosis among pregnant women attending antenatal care in Tikur Anbessa University Hospital, Addis Ababa, Ethiopia. BMC Res Notes. 2014;7:822. doi:10.1186/1756-0500-7-82225409756
  • Sobel JD. Vulvovaginal candidosis. Lancet. 2007;369(9577):1961–1971. doi:10.1016/S0140-6736(07)60917-917560449
  • Sobel JD, Subramanian C, Foxman B, Fairfax M, Gygax SE. Mixed vaginitis-more than coinfection and with therapeutic implications. Curr Infect Dis Rep. 2013;15(2):104–108. doi:10.1007/s11908-013-0325-523354954
  • Haltas H, Bayrak R, Yenidunya S. To determine of the prevalence of Bacterial Vaginosis, Candida sp, mixed infections (Bacterial Vaginosis + Candida sp), trichomonas vaginalis, actinomyces sp in Turkish women from Ankara, Turkey. Ginekol Pol. 2012;83(10):744–748.23383559
  • Sobel JD, Faro S, Force RW, et al. Vulvovaginal candidiasis: epidemiologic, diagnostic, and therapeutic considerations. Am J Obstet Gynecol. 1998;178(2):203–211. doi:10.1016/S0002-9378(98)80001-X9500475
  • Wiese W, Patel SR, Patel SC, Ohl CA, Estrada CA. A meta-analysis of the Papanicolaou smear and wet mount for the diagnosis of vaginal trichomoniasis. Am J Med. 2000;108(4):301–308. doi:10.1016/S0002-9343(99)00466-011014723
  • Nu PAT, Nguyen VQH, Cao NT, Dessì D, Rappelli P, Fiori PL. Prevalence of Trichomonas vaginalis infection in symptomatic and asymptomatic women in Central Vietnam. J Infect Dev Ctries. 2015;9(06):655–660. doi:10.3855/jidc.719026142677
  • Weinberger MW, Harger JH. Accuracy of the Papanicolaou smear in the diagnosis of asymptomatic infection with Trichomonas vaginalis. Obstet Gynecol. 1993;82(3):425–429.8355946
  • World Health Organization. Global Incidence and Prevalence of Selected Curable Sexually Transmitted Infections-2008; 2012.
  • Schönfeld A, Feldt T, Tufa TB, et al. Prevalence and impact of sexually transmitted infections in pregnant women in central Ethiopia. Int J STD AIDS. 2018;29(3):251–258. doi:10.1177/095646241772354528776463
  • Zenebe MH, Mekonnen Z, Loha E, Padalko E, Peters RP. Prevalence, risk factors and association with delivery outcome of curable sexually transmitted infections among pregnant women in Southern Ethiopia. PLoS One. 2021;16(3):e0248958. doi:10.1371/journal.pone.024895833760867
  • Eshete A, Mekonnen Z, Zeynudin A. Trichomonas vaginalis infection among pregnant women in Jimma University specialized hospital, southwest Ethiopia. Int Sch Res Notices. 2013;2013. doi:10.5402/2013/485439
  • Nugent RP, Krohn MA, Hillier SL. Reliability of diagnosing bacterial vaginosis is improved by a standardized method of gram stain interpretation. J Clin Microbiol. 1991;29(2):297–301. doi:10.1128/jcm.29.2.297-301.19911706728
  • Magiorakos A-P, Srinivasan A, Carey RB, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect. 2012;18(3):268–281. doi:10.1111/j.1469-0691.2011.03570.x21793988
  • M100. Performance Standards for Antimicrobial Susceptibility Testing [Internet]. Clinical & Laboratory Standards Institute; 2019.
  • Fan A, Yue Y, Geng N, Zhang H, Wang Y, Xue F. Aerobic vaginitis and mixed infections: comparison of clinical and laboratory findings. Arch Gynecol Obstet. 2013;287(2):329–335. doi:10.1007/s00404-012-2571-423015152
  • Donders GG, Van Calsteren K, Bellen G, et al. Predictive value for preterm birth of abnormal vaginal flora, bacterial vaginosis and aerobic vaginitis during the first trimester of pregnancy. BJOG. 2009;116(10):1315–1324. doi:10.1111/j.1471-0528.2009.02237.x19538417
  • Cheng L, Wang J. The vaginal micro-flora of aerobic vaginitis and bacterial vaginosis. Zhongguo Weishengtaxixue Zazhi. 2009;21(12):1107–1109.
  • Razzak MSA, Al-Charrakh AH, Al-Greitty BH. Relationship between lactobacilli and opportunistic bacterial pathogens associated with vaginitis. N Am J Med Sci. 2011;3(4):185–192. doi:10.4297/najms.2011.318522540089
  • Mobasheri M, Saeedi Varnamkhast N, Karimi A, Banaeiyan S. Prevalence study of genital tract infections in pregnant women referred to health centers in Iran. Turk J Med Sci. 2014;44(2):232–236. doi:10.3906/sag-1208-3325536729
  • Amanre I. Prevalence of bacterial and Candida albicans infection amongst women attending irrua specialist teaching hospital, Irrua, Nigeria. Afr J Microbiol Res. 2011;5(20):3126–3130. doi:10.5897/AJMR10.410
  • Nelson M, Wanjiru W, Margaret MW. Prevalence of vaginal candidiasis and determination of the occurrence of Candida species in pregnant women attending the antenatal clinic of Thika District Hospital, Kenya. Open J Med Microbiol. 2013;2013. doi:10.4236/ojmm.2013.34040
  • Bitew A, Abebaw Y. Vulvovaginal candidiasis: species distribution of Candida and their antifungal susceptibility pattern. BMC Women's Health. 2018;18(1):94. doi:10.1186/s12905-018-0607-z29902998
  • Kadir M, Sulyman M, Dawood I, Shams-Eldin S. Trichomonas vaginalis and associated microorganisms in women with vaginal discharge in Kerkuk-Iraq. Ank Med J. 2014;14(3):91–99. doi:10.17098/amj.47284
  • Abdelaziz ZA, Ibrahim ME, Bilal NE, Hamid ME. Vaginal infections among pregnant women at Omdurman Maternity Hospital in Khartoum, Sudan. J Infect Dev Ctries. 2014;8(4):490–497. doi:10.3855/jidc.319724727516
  • Madhivanan P, Bartman MT, Pasutti L, et al. Prevalence of Trichomonas vaginalis infection among young reproductive age women in India: implications for treatment and prevention. Sex Health. 2009;6(4):339–344. doi:10.1071/SH0903819917204
  • Zarbo G, Coco L, Leanza V, et al. Aerobic vaginitis during pregnancy. Res Obstet Gynecol. 2013;2(2):7–11.
  • Sangeetha KT, Golia S, Vasudha CL. A study of aerobic bacterial pathogens associated with vaginitis in reproductive age group women (15–45 years) and their sensitivity pattern. Int J Res Med Sci. 2017;3(9):2268–2273.
  • Han C, Wu W, Fan A, et al. Diagnostic and therapeutic advancements for aerobic vaginitis. Arch Gynecol Obstet. 2015;291(2):251–257. doi:10.1007/s00404-014-3525-925367602
  • Pal K, Sidhu SK, Devi P, et al; Department of Microbiology, Government Medical College, Amritsar, Punjab, India. Etiology of vaginal infections and antimicrobial resistance pattern of aerobic bacterial isolates in women of reproductive age group attending a tertiary care hospital. APJHS. 2017;4(4):15. doi:10.21276/apjhs.2017.4.4.5
  • Singh S, Swain S, Das L, Das PC, Sahoo S. Isolation and characterization of organisms in high vaginal swab culture in preterm pregnancy (28–37 week). Int J Reprod Contracept Obstet Gynecol. 2016;5(11):3853–3858. doi:10.18203/2320-1770.ijrcog20163853
  • Mumtaz S, Ahmad M, Aftab I, Akhtar N, Ul Hassan M, Hamid A. Aerobic vaginal pathogens and their sensitivity pattern. J Ayub Med Coll Abbottabad. 2008;20(1):113–117.19024202
  • Ventola CL. The antibiotic resistance crisis: part 1: causes and threats. Pharm Ther. 2015;40(4):277.
  • Donadu MG, Zanetti S, Nagy ÁL, Barrak I, Gajdács M. Insights on carbapenem-resistant Acinetobacter baumannii: phenotypic characterization of relevant isolates. Acta Biol Szeged. 2021;65(1):85–92. doi:10.14232/abs.2021.1.85-92
  • Gajdács M, Kárpáti K, Stájer A, Zanetti S, Donadu MG. Insights on carbapenem-resistant Pseudomonas aeruginosa: phenotypic characterization of relevant isolates. Acta Biol Szeged. 2021;65(1):105–112. doi:10.14232/abs.2021.1.105-112
  • Donadu MG, Peralta-Ruiz Y, Usai D, et al. Colombian essential oil of ruta graveolens against nosocomial antifungal resistant Candida strains. J Fungi. 2021;7(5):383. doi:10.3390/jof7050383
  • Donadu MG, Usai D, Marchetti M, et al. Antifungal activity of oils macerates of North Sardinia plants against Candida species isolated from clinical patients with candidiasis. Nat Prod Res. 2020;34(22):3280–3284. doi:10.1080/14786419.2018.155717530676066