533
Views
2
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Incidence and Predictors of Viral Load Suppression After Enhanced Adherence Counseling Among HIV-Positive Adults in West Gojjam Zone, Amhara Region, Ethiopia

, ORCID Icon, & ORCID Icon
Pages 261-274 | Published online: 25 Jan 2022

References

  • UNAIDS. Fact sheet - global HIV statistics; 2021. Available from: https://www.unaids.org/sites/default/files/media_asset/UNAIDS_FactSheet_en.pdf. Accessed November 06, 2021.
  • UNAIDS. Country factsheets Ethiopia AIDSinfo; 2020. Available from: https://aidsinfo.unaids.org/. Accessed September 10, 2020.
  • ARHB. EFY 2013 Eight Month HIV Prevention & Control Program Performance Review. Debre Tabor: ARHB; 2021.
  • Instiute eph. HIV Related Estimates and Projections in Ethiopia for the Year-2019. Addis Ababa; February, 2020:6.
  • Department WGZH. Annual Report on HIV/AIDS. unit WGZHdoHcat, ed. Fenotselam: West Gojjam Zone Health Department; 2019/2020.
  • UNAIDS. 90-90-90 An Ambitious Treatment Target to Help End the AIDSEpidemic. Geneva, Switzerland; 2017.
  • (1)PEPFAR. The global HIV/AIDS epidemic; 2019. Available from: https://www.hiv.gov/hiv-basics/overview/data-and-trends/global-statistics. Accessed July 07, 2020.
  • Acollaboration of UNAIDS UaW. Global factsheets AIDSinfo; 2021. Available from: https://aidsinfo.unaids.org/. Accessed August 10, 2021.
  • Organisation WH. Adapting and Implementing New Recommendation on HIV Patient Monitoring. Geneva, Switzerland; 2017.
  • WHO. Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection, Recommendations for a Public Health Approach. Geneva, Switzerland; 2016.
  • Reference U. The need for routine viral load testing; 2016. Available from: https://www.unaids.org/sites/default/files/media_asset/JC2845_en.pdf. Accessed December 31, 2021.
  • Ethiopia MoHo. National Guidelines for Comprehensive HIV Prevention Care and Treatment, 2019. Addis Ababa, Ethiopia; 2019.
  • Etoori D, Ciglenecki I, Ndlangamandla M, et al. Successes and challenges in optimizing the viral load cascade to improve antiretroviral therapy adherence and rationalize second-line switches in Swaziland. J Int AIDS Soc. 2018;21(10):e25194. doi:10.1002/jia2.25194
  • Minstery of Health E. National Consolidated Guidelines for Comprehensive HIV Prevention, Care and Treatment. Addis Ababa: MoH; 2018.
  • Kerschberger B, Boulle AM, Kranzer K, et al. Superior virologic and treatment outcomes when viral load is measured at 3 months compared to 6 months on antiretroviral therapy. J Int AIDS Soc. 2015;18(1):20092. doi:10.7448/IAS.18.1.20092
  • (1)USAIDS. Global and regional statistics on the status of the AIDS epidemic. Available from: https://www.unaids.org/sites/default/files/media_asset/UNAIDS_FactSheet_en.pdf. Accessed August 22, 2021.
  • Diress G, Dagne S, Alemnew B, Adane S, Addisu A. Viral load suppression after enhanced adherence counseling and its predictors among high viral load HIV seropositive people in North Wollo Zone Public Hospitals, Northeast Ethiopia, 2019: Retrospective Cohort Study. AIDS Res Treat. 2020;2020:1–9. doi:10.1155/2020/8909232
  • Fox Z, Phillips A, Cohen C, et al. Viral re-suppression and detection of drug resistance following interruption of a suppressive NNRTI-based regimen. AIDS. 2008;22(17):2279. doi:10.1097/QAD.0b013e328311d16f
  • Leisegang R, Stewart A, Sunpath H, et al. Short term adherence tool predicts failure on second line protease inhibitor-based antiretroviral therapy: an observational cohort study. BMC Infect Dis. 2014;14(1):664. doi:10.1186/s12879-014-0664-3
  • Aidsmap. viral load; 2017. Review date May, 2017. Available from: https://www.aidsmap.com/about-hiv/viral-load. Accessed December 31, 2021.
  • Ahmed M, Merga H, Jarso H. Predictors of virological treatment failure among adult HIV patients on first-line antiretroviral therapy in Woldia and Dessie hospitals, Northeast Ethiopia: a case-control study. BMC Infect Dis. 2019;19(1):1–7. doi:10.1186/s12879-019-3924-4
  • Maina E, Mureithi H, Adan A, Muriuki J, Lwembe R, Bukusi E. Incidences and factors associated with viral suppression or rebound among HIV patients on combination antiretroviral therapy from three counties in Kenya. Int J Infect Dis. 2020;97:151–158. doi:10.1016/j.ijid.2020.05.097
  • Ali JH, Yirtaw TG. Time to viral load suppression and its associated factors in cohort of patients taking antiretroviral treatment in East Shewa zone, Oromiya, Ethiopia, 2018. BMC Infect Dis. 2019;19(1):1084. doi:10.1186/s12879-019-4702-z
  • Orrell C, Harling G, Lawn SD, et al. Conservation of first-line antiretroviral treatment regimen where therapeutic options are limited. Antivir Ther. 2007;12(1):83.
  • Hussen S, Mama M, Mekonnen B, et al. Predictors of time to viral load suppression of adult PLWHIV on ART in Arba Minch General Hospital: a Follow up Study. Ethiop J Health Sci. 2019;29(6):751–758. doi:10.4314/ejhs.v29i6.12
  • d’Arminio Monforte A, Testa L, Adorni F, et al. Clinical outcome and predictive factors of failure of highly active antiretroviral therapy in antiretroviral-experienced patients in advanced stages of HIV-1 infection. AIDS. 1998;12(13):1631–1637. doi:10.1097/00002030-199813000-00010
  • Thiébaut R, Morlat P, Jacqmin-Gadda H, et al. Clinical progression of HIV-1 infection according to the viral response during the first year of antiretroviral treatment. Groupe d’Epidémiologie du SIDA en Aquitaine (GECSA). AIDS. 2000;14(8):971–978. doi:10.1097/00002030-200005260-00008
  • Kipp W, Alibhai A, Saunders LD, et al. Gender differences in antiretroviral treatment outcomes of HIV patients in rural Uganda. AIDS Care. 2010;22(3):271–278. doi:10.1080/09540120903193625
  • Haider MR, Brown MJ, Harrison S. Sociodemographic factors affecting viral load suppression among people living with HIV in South Carolina. AIDS Care. 2021;33(3):290–298. doi:10.1080/09540121.2019.1703892
  • Bvochora T, Satyanarayana S, Takarinda KC, et al. Enhanced adherence counselling and viral load suppression in HIV seropositive patients with an initial high viral load in Harare, Zimbabwe: operational issues. PLoS One. 2019;14(2):e0211326. doi:10.1371/journal.pone.0211326
  • Hicham T, Ilyas E, Tarik H, et al. Risk factors associated with unsuppressed viral load in HIV-1 infected patients at the first antiretroviral therapy in Morocco. Int J Mycobacteriol. 2019;8(2):113. doi:10.4103/ijmy.ijmy_41_19
  • Jobanputra K, Parker LA, Azih C, et al. Factors associated with virological failure and suppression after enhanced adherence counselling, in children, adolescents and adults on antiretroviral therapy for HIV in Swaziland. PLoS One. 2015;10(2):e0116144. doi:10.1371/journal.pone.0116144
  • Joseph Davey D, Abrahams Z, Feinberg M, et al. Factors associated with recent unsuppressed viral load in HIV-1-infected patients in care on first-line antiretroviral therapy in South Africa. Int J STD AIDS. 2018;29(6):11–14. doi:10.1177/0956462417748859
  • Ekwaru JP, Campbell J, Malamba S, Moore D, Were W, Mermin J. The effect of opportunistic illness on HIV RNA viral load and CD4+ T cell count among HIV-positive adults taking antiretroviral therapy. J Int AIDS Soc. 2013;16:17355. doi:10.7448/IAS.16.1.17355
  • Yehia BR, Stephens-Shield AJ, Momplaisir F, et al. Health outcomes of HIV-infected people with mental illness. AIDS Behav. 2015;19(8):4–5. doi:10.1007/s10461-015-1080-4
  • Hartzell JD, Janke IE, Weintrob AC. Impact of depression on HIV outcomes in the HAART era. J Antimicrob Chemother. 2008;62(2):246–255. doi:10.1093/jac/dkn193
  • Modi RA. HIV Disclosure, Retention in HIV Care, and Viral Load Suppression: A Study Among New to HIV Care Patients. The University of Alabama at Birmingham; 2018.